Xuefeng Zhu

Summary

Country: Sweden

Publications

  1. pmc Distinct differences in chromatin structure at subtelomeric X and Y' elements in budding yeast
    Xuefeng Zhu
    Department of Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden
    PLoS ONE 4:e6363. 2009
  2. pmc Mediator influences telomeric silencing and cellular life span
    Xuefeng Zhu
    Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Medicinaregatan 9A, SE 40530 Goteborg, Sweden
    Mol Cell Biol 31:2413-21. 2011
  3. pmc Histone modifications influence mediator interactions with chromatin
    Xuefeng Zhu
    Department of Biochemistry and Cell Biology, University of Gothenburg, SE 405 30 Gothenburg, Sweden
    Nucleic Acids Res 39:8342-54. 2011
  4. doi request reprint The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication
    Bertil Macao
    Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Medicinaregatan 9 A, P O Box 440, SE 40530 Gothenburg, Sweden
    Nat Commun 6:7303. 2015
  5. doi request reprint Mediator tail subunits can form amyloid-like aggregates in vivo and affect stress response in yeast
    Xuefeng Zhu
    Institute of Biomedicine, University of Gothenburg, P O Box 440, SE 405 30 Goteborg, Sweden
    Nucleic Acids Res 43:7306-14. 2015
  6. pmc Mediator promotes CENP-a incorporation at fission yeast centromeres
    Jonas O Carlsten
    Institute of Biomedicine, University of Gothenburg, Goteborg, Sweden
    Mol Cell Biol 32:4035-43. 2012
  7. doi request reprint The multitalented Mediator complex
    Jonas O P Carlsten
    University of Gothenburg, Institute of Biomedicine, PO Box 440, 40530 Gothenburg, Sweden
    Trends Biochem Sci 38:531-7. 2013
  8. pmc In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication
    Javier Miralles Fusté
    Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden
    PLoS Genet 10:e1004832. 2014

Collaborators

Detail Information

Publications8

  1. pmc Distinct differences in chromatin structure at subtelomeric X and Y' elements in budding yeast
    Xuefeng Zhu
    Department of Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden
    PLoS ONE 4:e6363. 2009
    ..Our analyses suggest that the presence of X and Y' elements govern chromatin structure and transcription activity at individual chromosome ends...
  2. pmc Mediator influences telomeric silencing and cellular life span
    Xuefeng Zhu
    Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Medicinaregatan 9A, SE 40530 Goteborg, Sweden
    Mol Cell Biol 31:2413-21. 2011
    ..Increases in H4K16 acetylation have been observed at telomeres in aging cells. In agreement with this observation, we found that the loss of MED5 leads to shortening of the Saccharomyces cerevisiae (budding yeast) replicative life span...
  3. pmc Histone modifications influence mediator interactions with chromatin
    Xuefeng Zhu
    Department of Biochemistry and Cell Biology, University of Gothenburg, SE 405 30 Gothenburg, Sweden
    Nucleic Acids Res 39:8342-54. 2011
    ..Our studies show that chromatin structure and the acetylation state of histones are intimately connected to Mediator localization...
  4. doi request reprint The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication
    Bertil Macao
    Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Medicinaregatan 9 A, P O Box 440, SE 40530 Gothenburg, Sweden
    Nat Commun 6:7303. 2015
    ..In the subsequent round of replication, the nicks lead to double-strand breaks and linear fragment formation. ..
  5. doi request reprint Mediator tail subunits can form amyloid-like aggregates in vivo and affect stress response in yeast
    Xuefeng Zhu
    Institute of Biomedicine, University of Gothenburg, P O Box 440, SE 405 30 Goteborg, Sweden
    Nucleic Acids Res 43:7306-14. 2015
    ..In combination with genome wide transcription analysis, our data demonstrate that amyloid formation can change the subunit composition of Mediator and thereby influence transcriptional output in budding yeast...
  6. pmc Mediator promotes CENP-a incorporation at fission yeast centromeres
    Jonas O Carlsten
    Institute of Biomedicine, University of Gothenburg, Goteborg, Sweden
    Mol Cell Biol 32:4035-43. 2012
    ..Our data thus identify Mediator as a crucial regulator of ncRNA transcription at fission yeast centromeres and add another crucial layer of regulation to centromere function...
  7. doi request reprint The multitalented Mediator complex
    Jonas O P Carlsten
    University of Gothenburg, Institute of Biomedicine, PO Box 440, 40530 Gothenburg, Sweden
    Trends Biochem Sci 38:531-7. 2013
    ..We also discuss the inherent difficulties associated with in vivo characterization of a coactivator complex that can indirectly affect diverse cellular processes via changes in gene transcription. ..
  8. pmc In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication
    Javier Miralles Fusté
    Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden
    PLoS Genet 10:e1004832. 2014
    ..The pattern correlates with the replication products expected for the strand displacement mode of mtDNA synthesis, lending strong in vivo support for this debated model for mitochondrial DNA replication. ..