L Wilhelmsen

Summary

Country: Sweden

Publications

  1. ncbi request reprint Role of the Data and Safety Monitoring Committee (DSMC)
    Lars Wilhelmsen
    The Cardiovascular Institute, Goteborg University, Drakegatan 6, 5 tr, SE 412 50 Göteborg, Sweden
    Stat Med 21:2823-9. 2002
  2. ncbi request reprint Heart failure in the general population of men--morbidity, risk factors and prognosis
    L Wilhelmsen
    Section of Preventive Cardiology, Goteborg University, Goteborg, Sweden
    J Intern Med 249:253-61. 2001
  3. ncbi request reprint Hospitalizations for atrial fibrillation in the general male population: morbidity and risk factors
    L Wilhelmsen
    Section of Preventive Cardiology, The Cardiovascular Institute, Goteborg University, Sweden
    J Intern Med 250:382-9. 2001
  4. ncbi request reprint [Risk factors smoking, serum cholesterol and blood pressure analyzed. Excess risk also in the "moderate" groups]
    Lars Wilhelmsen
    Hjärt kärlinstitutionen, Göteborgs Universitet
    Lakartidningen 99:4966-73. 2002
  5. doi request reprint Factors associated with reaching 90 years of age: a study of men born in 1913 in Gothenburg, Sweden
    L Wilhelmsen
    Section of Preventive Cardiology, Sahlgrenska University Hospital Ostra, Sahlgrenska Academy, University of Gothenburg, Sweden
    J Intern Med 269:441-51. 2011
  6. doi request reprint Obesity and trends in cardiovascular risk factors over 40 years in Swedish men aged 50
    A Rosengren
    Department of Emergency and Cardiovascular Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 266:268-76. 2009
  7. doi request reprint Obesity, smoking and secular trends in cardiovascular risk factors in middle-aged women: data from population studies in Göteborg from 1980 to 2003
    S Johansson
    Department of Emergency and Cardiovascular Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 268:594-603. 2010
  8. ncbi request reprint Secular changes in cardiovascular risk factors over 30 years in Swedish men aged 50: the study of men born in 1913, 1923, 1933 and 1943
    A Rosengren
    Section of Preventive Cardiology, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 247:111-8. 2000
  9. ncbi request reprint Osteoporosis and fractures in Turner syndrome-importance of growth promoting and oestrogen therapy
    K Landin-Wilhelmsen
    Research Centre for Endocrinology and Metabolism, Sahlgrenska University Hospital, Goteborg, Sweden
    Clin Endocrinol (Oxf) 51:497-502. 1999
  10. doi request reprint Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models
    L Wilhelmsen
    Section of Preventive Cardiology, Goteborg University, Goteborg, Sweden
    J Intern Med 263:636-43. 2008

Collaborators

Detail Information

Publications46

  1. ncbi request reprint Role of the Data and Safety Monitoring Committee (DSMC)
    Lars Wilhelmsen
    The Cardiovascular Institute, Goteborg University, Drakegatan 6, 5 tr, SE 412 50 Göteborg, Sweden
    Stat Med 21:2823-9. 2002
    ..Legal requirements to report serious adverse events to legal authorities may be taken over by the DSMC, which ideally is the only body that has access to unblinded data...
  2. ncbi request reprint Heart failure in the general population of men--morbidity, risk factors and prognosis
    L Wilhelmsen
    Section of Preventive Cardiology, Goteborg University, Goteborg, Sweden
    J Intern Med 249:253-61. 2001
    ..To analyse the prevalence, aetiology and prognosis of heart failure...
  3. ncbi request reprint Hospitalizations for atrial fibrillation in the general male population: morbidity and risk factors
    L Wilhelmsen
    Section of Preventive Cardiology, The Cardiovascular Institute, Goteborg University, Sweden
    J Intern Med 250:382-9. 2001
    ..To analyse the incidence, prevalence, aetiology, risk factors and prognosis of hospitalizations for atrial fibrillation...
  4. ncbi request reprint [Risk factors smoking, serum cholesterol and blood pressure analyzed. Excess risk also in the "moderate" groups]
    Lars Wilhelmsen
    Hjärt kärlinstitutionen, Göteborgs Universitet
    Lakartidningen 99:4966-73. 2002
    ..Non-pharmacological measures are indicated to reduce these levels...
  5. doi request reprint Factors associated with reaching 90 years of age: a study of men born in 1913 in Gothenburg, Sweden
    L Wilhelmsen
    Section of Preventive Cardiology, Sahlgrenska University Hospital Ostra, Sahlgrenska Academy, University of Gothenburg, Sweden
    J Intern Med 269:441-51. 2011
    ..Increasing numbers of people reach old age. We wanted to identify variables of importance for reaching 90 years old and determine how the predictive ability of these variables might change over time...
  6. doi request reprint Obesity and trends in cardiovascular risk factors over 40 years in Swedish men aged 50
    A Rosengren
    Department of Emergency and Cardiovascular Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 266:268-76. 2009
    ..To study trends over 40 years in cardiovascular risk factors in normal weight, overweight and obese men, all aged 50 when examined. Design. Cross-sectional studies of five successive cohorts of men aged 50...
  7. doi request reprint Obesity, smoking and secular trends in cardiovascular risk factors in middle-aged women: data from population studies in Göteborg from 1980 to 2003
    S Johansson
    Department of Emergency and Cardiovascular Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 268:594-603. 2010
    ..To study the trends in cardiovascular risk factors in middle-aged city-dwelling Swedish women from 1980 to 2003...
  8. ncbi request reprint Secular changes in cardiovascular risk factors over 30 years in Swedish men aged 50: the study of men born in 1913, 1923, 1933 and 1943
    A Rosengren
    Section of Preventive Cardiology, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 247:111-8. 2000
    ..To study secular trends in cardiovascular risk factors in men aged 50 over a period of 30 years...
  9. ncbi request reprint Osteoporosis and fractures in Turner syndrome-importance of growth promoting and oestrogen therapy
    K Landin-Wilhelmsen
    Research Centre for Endocrinology and Metabolism, Sahlgrenska University Hospital, Goteborg, Sweden
    Clin Endocrinol (Oxf) 51:497-502. 1999
    ..The aim was to study body composition, bone mineral density, fracture frequency, social and life style factors and biochemical bone markers, as well as hormones, in adults with TS in comparison with a female random population sample...
  10. doi request reprint Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models
    L Wilhelmsen
    Section of Preventive Cardiology, Goteborg University, Goteborg, Sweden
    J Intern Med 263:636-43. 2008
    ..Coronary risk factor changes were related to attack rate of acute myocardial infarction (AMI)...
  11. ncbi request reprint Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men
    A Rosengren
    Department of Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Thromb Haemost 6:558-64. 2008
    ....
  12. ncbi request reprint Calcaneal ultrasound measurements are determined by age and physical activity. Studies in two Swedish random population samples
    K Landin-Wilhelmsen
    Research Centre for Endocrinology, Section of Preventive Cardiology, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden
    J Intern Med 247:269-78. 2000
    ..To present reference values and correlations with body composition, blood variables and lifestyle factors...
  13. ncbi request reprint Postmenopausal osteoporosis is more related to hormonal aberrations than to lifestyle factors
    K Landin-Wilhelmsen
    Research Centre for Endocrinology and Metabolism, Department of Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
    Clin Endocrinol (Oxf) 51:387-94. 1999
    ....
  14. ncbi request reprint Hypertension and long-term cancer incidence and mortality among Swedish men
    A Rosengren
    Section of Preventive Cardiology, Sahlgrenska University Hospital, Ostra, Goteborg, Sweden
    J Hypertens 16:933-40. 1998
    ..To examine incidence of cancer and cancer mortality in relation to high blood pressure...
  15. ncbi request reprint Cardiac malformations and hypertension, but not metabolic risk factors, are common in Turner syndrome
    K Landin-Wilhelmsen
    Research Center for Endocrinology and Metabolism, Sahlgrenska University Hospital, Goteborg, Sweden
    J Clin Endocrinol Metab 86:4166-70. 2001
    ..In conclusion, congenital cardiovascular malformations were frequent. Most cardiovascular risk factors (glucose and lipid levels, fibrinogen, smoking habits) were not increased, but hypertension was more common in Turner syndrome women...
  16. ncbi request reprint Coronary risk factors, diet and vitamins as possible explanatory factors of the Swedish north-south gradient in coronary disease: a comparison between two MONICA centres
    A Rosengren
    Department of Preventive Cardiology, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 246:577-86. 1999
    ..To investigate whether differences in serum lipids, diet, plasma vitamins or other risk factors explain the higher incidence of cardiovascular disease in the northern parts of Sweden, compared to Göteborg on the west coast...
  17. ncbi request reprint Coffee and incidence of diabetes in Swedish women: a prospective 18-year follow-up study
    A Rosengren
    Department of Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    J Intern Med 255:89-95. 2004
    ..To examine the long-term incidence of diabetes in relation to coffee consumption in Swedish women...
  18. ncbi request reprint Stroke and coronary heart disease in treated hypertension -- a prospective cohort study over three decades
    T Almgren
    Hypertension Clinic, Department of Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
    J Intern Med 257:496-502. 2005
    ....
  19. ncbi request reprint Risk of coronary events by baseline factors during 28 years follow-up and three periods in a random population sample of men
    L Wilhelmsen
    Section of Preventive Cardiology, The Cardiovascular Institute, Goteborg University, Drakegatan 6, SE 412 50 Göteborg, Sweden
    J Intern Med 256:298-307. 2004
    ..To investigate the predictive value of risk factors for coronary events measured in midlife during three separate periods over a follow-up period extending through 28 years...
  20. ncbi request reprint Autoantibodies against oxidized low-density lipoprotein and C-reactive protein are associated with diabetes and myocardial infarction in women
    A Dotevall
    Section of Preventive Cardiology, Department of Medicine, SU/Ostra, Sahlgrenska University Hospital, , , Sweden
    Clin Sci (Lond) 101:523-31. 2001
    ..These findings might indicate a differentiated immune response against modified LDL, more pronounced inflammation and a more aggressive atherosclerotic process in women with diabetes...
  21. ncbi request reprint Parental age and coronary disease in the general male population
    A Rosengren
    Preventive Cardiology, Sahlgrenska University Hospital, Ostra, Goteborg, Sweden
    J Intern Med 251:258-67. 2002
    ..To investigate the role of achieved age in father or mother for long-term prognosis in men with respect to fatal and nonfatal coronary events, and mortality from cardiovascular disease, cancer, and all causes...
  22. ncbi request reprint Application of a disease-specific, quality-of-life measure (QoL-AGHDA) in growth hormone-deficient adults and a random population sample in Sweden: validation of the measure by rasch analysis
    L Wiren
    Research Centre for Endocrinology and Metabolism, Sahlgrenska University Hospital, Goteborg, Sweden
    Clin Endocrinol (Oxf) 52:143-52. 2000
    ..The study also sought to compare, by using the QoL-AGHDA, the QoL of a relatively large Swedish cohort of adults with untreated GHD with that of a reference population also from Sweden...
  23. ncbi request reprint Effects of cessation of smoking after myocardial infarction
    L Wilhelmsen
    Section of Preventive Cardiology, Goteborg University, Sweden
    J Cardiovasc Risk 5:173-6. 1998
    ....
  24. ncbi request reprint Preserved tissue-type plasminogen activator release and endothelium-dependent vasodilation in postmenopausal women with NIDDM
    K Manhem
    Clinical Experimental Research Laboratory, Sahlgrenska University Hospital, East Göteborg University, Goteborg, Sweden
    J Diabetes Complications 14:127-34. 2000
    ..Acute intra-arterial infusion of 17-beta estradiol did not affect the vasodilation or the t-PA net release...
  25. ncbi request reprint Long-term risk factors for stroke: twenty-eight years of follow-up of 7457 middle-aged men in Göteborg, Sweden
    Per Harmsen
    Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg, Sweden
    Stroke 37:1663-7. 2006
    ..To estimate the predictive value of risk factors for stroke measured in midlife over follow-up extending through 28 years...
  26. ncbi request reprint Trends in blood lipid levels, blood pressure, alcohol and smoking habits from 1985 to 2002: results from INTERGENE and GOT-MONICA
    Christina M Berg
    The Cardiovascular Institute, Sahlgrenska Academy at Goteborg University, Göteborg bInstitute of Community Medicine Primary Health Care, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Eur J Cardiovasc Prev Rehabil 12:115-25. 2005
    ..Favourable trends in cardiovascular disease have been observed in Sweden. The aim of this study was to study secular trends in a variety of cardiovascular risk factors...
  27. ncbi request reprint [The Swedish SCORE chart for cardiovascular risk. Better possibilities for prevention of cardiovascular diseases]
    Lars Wilhelmsen
    Hjärt kärlinstitutionen, Göteborgs Universitet
    Lakartidningen 101:1798-801. 2004
  28. ncbi request reprint Predictors of coronary bypass grafting in a population of middle-aged men
    Kerstin A Dudas
    Department of Medicine, Sahlgrenska University Hospital, Ostra, Goteborg, Sweden
    Eur J Cardiovasc Prev Rehabil 14:122-7. 2007
    ..The aim of this study was to assess risk factors for future coronary bypass grafting as a first coronary event, and to compare them with risk factors for a first acute myocardial infarction...
  29. ncbi request reprint Chromosomal mosaicism mitigates stigmata and cardiovascular risk factors in Turner syndrome
    Mostafa El-Mansoury
    Department of Internal Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    Clin Endocrinol (Oxf) 66:744-51. 2007
    ..To study genotype-phenotype correlations in Turner syndrome (TS) regarding body composition, cardiovascular risk factors, stigmata and age at diagnosis vs. degree of mosaicism estimated as the percentage of 45,X and 46,XX cells...
  30. ncbi request reprint Diabetes in treated hypertension is common and carries a high cardiovascular risk: results from a 28-year follow-up
    Torbjörn Almgren
    Department of Internal Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
    J Hypertens 25:1311-7. 2007
    ..The objective of this study was to analyse predictive factors for development of type 2 diabetes during life-long therapy for hypertension and the alleged additional cardiovascular risk this constitutes...
  31. doi request reprint Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial
    Anne Katrin Sjølie
    Department of Ophthalmology, Odense University Hospital, Odense, Denmark
    Lancet 372:1385-93. 2008
    ..Diabetic retinopathy remains a leading cause of visual loss in people of working age. We examined whether candesartan treatment could slow the progression and, secondly, induce regression of retinopathy in people with type 2 diabetes...
  32. ncbi request reprint High lipid levels and coronary disease in women in Göteborg--outcome and secular trends: a prospective 19 year follow-up in the BEDA*study
    Saga Johansson
    Department of Medicine, The Cardiovascular Institute, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    Eur Heart J 24:704-16. 2003
    ....
  33. ncbi request reprint Bundle-branch block in middle-aged men: risk of complications and death over 28 years. The Primary Prevention Study in Göteborg, Sweden
    Peter Eriksson
    Clinical Experimental Research Lab, The Cardiovascular Institute, Goteborg University, Drakeg 6, SE 41250 Göteborg, Sweden
    Eur Heart J 26:2300-6. 2005
    ..To investigate the long-term fate of men with bundle-branch block (BBB) from a general population sample...
  34. ncbi request reprint Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial
    John A Dormandy
    Department of Clinical Vascular Research, Ingelby House, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK
    Lancet 366:1279-89. 2005
    ..Our aim, therefore, was to ascertain whether pioglitazone reduces macrovascular morbidity and mortality in high-risk patients with type 2 diabetes...
  35. ncbi request reprint Differences between coronary disease and stroke in incidence, case fatality, and risk factors, but few differences in risk factors for fatal and non-fatal events
    Lars Wilhelmsen
    Section of Preventive Cardiology, The Cardiovascular Institute, Goteborg University, Drakegatan 6, SE 412 50 Göteborg, Sweden lars wilhelmsen scri se
    Eur Heart J 26:1916-22. 2005
    ..To compare incidence and mortality of coronary and stroke events, and risk factors for non-fatal and fatal events, respectively...
  36. ncbi request reprint Cancer incidence, mortality from cancer and survival in men of different occupational classes
    Annika Rosengren
    Section of Preventive Cardiology, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    Eur J Epidemiol 19:533-40. 2004
    ..75 (95% confidence interval 1.22-2.50) in unskilled workers compared to higher officials (p for trend 0.015)...
  37. ncbi request reprint Coronary disease in relation to social support and social class in Swedish men. A 15 year follow-up in the study of men born in 1933
    Annika Rosengren
    Department of Medicine, Sahlgrenska University Hospital Ostra, SE 416 85 Goteborg, Sweden
    Eur Heart J 25:56-63. 2004
    ..In this prospective cohort study of men we sought to estimate the impact of social network factors on the risk of incident coronary heart disease and mortality from all causes...
  38. ncbi request reprint Body mass index in mid-life is associated with a first stroke in men: a prospective population study over 28 years
    Katarina Jood
    Institute of Clinical Neuroscience, Department of Neurology, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Stroke 35:2764-9. 2004
    ..We examined the possible association between mid-life body mass index (BMI) and risk of stroke in the prospective Multifactor Primary Prevention Study in Göteborg, Sweden...
  39. ncbi request reprint The data monitoring experience in the MOXCON trial
    Stuart Pocock
    Medical Statistics Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Eur Heart J 25:1974-8. 2004
    ....
  40. ncbi request reprint [New European guidelines for cardiovascular prevention]
    Lars Wilhelmsen
    Hjärt kärlinstitutionen, Göteborgs Universitet, Goteborg
    Lakartidningen 101:3677-8, 3680-2. 2004
  41. ncbi request reprint Considerable disturbances of cardiovascular risk factors in women with diabetes and myocardial infarction
    Annika Dotevall
    Section of Preventive Cardiology, Department of Medicine, Sahlgrenska University, Hospital Ostra, Goteborg University, S 416 85 Goteborg, Sweden
    J Diabetes Complications 19:26-34. 2005
    ..To investigate to which extent differences in cardiovascular risk factors explain the increased risk of myocardial infarction (MI) and complication rate in women with diabetes mellitus (DM)...
  42. ncbi request reprint Body mass index, coronary heart disease and stroke in Swedish women. A prospective 19-year follow-up in the BEDA study
    Annika Rosengren
    The Cardiovascular Institute, Department of Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    Eur J Cardiovasc Prev Rehabil 10:443-50. 2003
    ..Although obesity is an important determinant of an unfavourable risk factor pattern reported associations between cardiovascular disease and obesity in women have been remarkably inconsistent...
  43. ncbi request reprint The data monitoring experience in the Candesartan in Heart Failure Assessment of Reduction in Mortality and morbidity (CHARM) program
    Stuart Pocock
    Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am Heart J 149:939-43. 2005
    ..40; (2) were on angiotensin-converting enzyme inhibitor and had LVEF < or =0.40; or (3) had LVEF >0.40. CHARM provides an interesting example of the challenges faced by a Data and Safety Monitoring Committee (DSMC)...
  44. ncbi request reprint [New European diagrams for assessment of cardiovascular risk]
    Lars Wilhelmsen
    Hiärt kärlinstitutionen, Göteborgs Universitet, Goteborg
    Lakartidningen 100:2764-6. 2003
  45. ncbi request reprint Optimising health care within given budgets: primary prevention of cardiovascular disease in different regions of Sweden
    Emil Löfroth
    Department of Public Health and Clinical Medicine, Umeå University Centre for Epidemiology, National Board of Health and Welfare, SE 106 30, Stockholm, Sweden
    Health Policy 75:214-29. 2006
    ..One advantage of this method is that the results are very concrete. Recommendations can thereby be more precise which hopefully will create a public debate between decision-makers, practising physicians and patient groups...
  46. ncbi request reprint Trends in the prevalence, awareness, treatment and control of hypertension: the WHO MONICA Project
    Riitta L Antikainen
    Department of Internal Medicine, University of Oulu and Oulu City Hospital, Oulu, Finland
    Eur J Cardiovasc Prev Rehabil 13:13-29. 2006
    ..To describe the secular changes in the prevalence, awareness, treatment and control of hypertension...