Jenny Welander

Summary

Country: Sweden

Publications

  1. ncbi request reprint Frequent EPAS1/HIF2α exons 9 and 12 mutations in non-familial pheochromocytoma
    Jenny Welander
    Department of Clinical and Experimental MedicineFaculty of Health Sciences, Linkoping University, Linköping SE 58185, SwedenDepartment of Oncology PathologyKarolinska Institutet, CCK, Karolinska University Hospital, Stockholm SE 17176, SwedenDepartment of SurgeryHaukeland University Hospital, Bergen, NorwayDepartment of Clinical ScienceUniversity of Bergen, Bergen NO 5021, NorwayDepartment of Molecular Medicine and SurgeryKarolinska Institutet, Karolinska University Hospital, Stockholm SE 17176, SwedenDepartment of SurgeryCounty Council of Östergötland, Linköping SE 58185, Sweden
    Endocr Relat Cancer 21:495-504. 2014
  2. doi request reprint Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas
    Jenny Welander
    Department of Clinical and Experimental Medicine, Linkoping University, Linkoping, Sweden
    Hum Mol Genet 21:5406-16. 2012
  3. doi request reprint The NF1 gene: a frequent mutational target in sporadic pheochromocytomas and beyond
    Jenny Welander
    Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    Endocr Relat Cancer 20:C13-7. 2013
  4. ncbi request reprint Rare germline mutations identified by targeted next-generation sequencing of susceptibility genes in pheochromocytoma and paraganglioma
    Jenny Welander
    Department of Clinical and Experimental Medicine J W, O G, P S, Faculty of Health Sciences, Linkoping University, Departments of Surgery O G and Clinical Genetics P S, County Council of Ostergotland, Linköping SE 58185, Sweden Department of Oncology Pathology A A, C C J, A H, C L, Karolinska Institutet, Cancer Center Karolinska A A, C C J, A H, C L, Karolinska University Hospital Solna, and Department of Molecular Medicine and Surgery A A, C C J, M B, C L, Karolinska Institutet, Karolinska University Hospital, Stockholm SE 17176, Sweden and Wisconsin National Primate Research Center R W W, University of Wisconsin Madison, Madison, Wisconsin 53715
    J Clin Endocrinol Metab 99:E1352-60. 2014
  5. doi request reprint Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas
    Jenny Welander
    Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, 58185 Linkoping, Sweden
    Endocr Relat Cancer 18:R253-76. 2011
  6. doi request reprint Role of SDHAF2 and SDHD in von Hippel-Lindau associated pheochromocytomas
    Johan Kugelberg
    Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    World J Surg 38:724-32. 2014

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Frequent EPAS1/HIF2α exons 9 and 12 mutations in non-familial pheochromocytoma
    Jenny Welander
    Department of Clinical and Experimental MedicineFaculty of Health Sciences, Linkoping University, Linköping SE 58185, SwedenDepartment of Oncology PathologyKarolinska Institutet, CCK, Karolinska University Hospital, Stockholm SE 17176, SwedenDepartment of SurgeryHaukeland University Hospital, Bergen, NorwayDepartment of Clinical ScienceUniversity of Bergen, Bergen NO 5021, NorwayDepartment of Molecular Medicine and SurgeryKarolinska Institutet, Karolinska University Hospital, Stockholm SE 17176, SwedenDepartment of SurgeryCounty Council of Östergötland, Linköping SE 58185, Sweden
    Endocr Relat Cancer 21:495-504. 2014
    ..One of the tumors with an EPAS1 mutation also had a gain in DNA copy number at the EPAS1 locus. All EPAS1-mutated tumors displayed a pseudo-hypoxic gene expression pattern, indicating an oncogenic role of the identified mutations. ..
  2. doi request reprint Integrative genomics reveals frequent somatic NF1 mutations in sporadic pheochromocytomas
    Jenny Welander
    Department of Clinical and Experimental Medicine, Linkoping University, Linkoping, Sweden
    Hum Mol Genet 21:5406-16. 2012
    ..Our results thus suggest that the NF1 gene constitutes the most frequent (24%) target of somatic mutations so far known in sporadic pheochromocytomas...
  3. doi request reprint The NF1 gene: a frequent mutational target in sporadic pheochromocytomas and beyond
    Jenny Welander
    Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    Endocr Relat Cancer 20:C13-7. 2013
    ..A literature and public mutation database review has revealed that pheochromocytomas are among those human neoplasms in which somatic NF1 alterations are most frequent. ..
  4. ncbi request reprint Rare germline mutations identified by targeted next-generation sequencing of susceptibility genes in pheochromocytoma and paraganglioma
    Jenny Welander
    Department of Clinical and Experimental Medicine J W, O G, P S, Faculty of Health Sciences, Linkoping University, Departments of Surgery O G and Clinical Genetics P S, County Council of Ostergotland, Linköping SE 58185, Sweden Department of Oncology Pathology A A, C C J, A H, C L, Karolinska Institutet, Cancer Center Karolinska A A, C C J, A H, C L, Karolinska University Hospital Solna, and Department of Molecular Medicine and Surgery A A, C C J, M B, C L, Karolinska Institutet, Karolinska University Hospital, Stockholm SE 17176, Sweden and Wisconsin National Primate Research Center R W W, University of Wisconsin Madison, Madison, Wisconsin 53715
    J Clin Endocrinol Metab 99:E1352-60. 2014
    ..KIF1Bβ, which previously has not been investigated in a large cohort, appears to be an equally important tumor suppressor as MAX and TMEM127 and could be considered for genetic testing of these patients. ..
  5. doi request reprint Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas
    Jenny Welander
    Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, 58185 Linkoping, Sweden
    Endocr Relat Cancer 18:R253-76. 2011
    ..Further, the latest advances in elucidating the cellular pathways involved in PCC and PGL development are discussed in detail. Finally, an algorithm for genetic testing in patients with PCC and PGL is proposed...
  6. doi request reprint Role of SDHAF2 and SDHD in von Hippel-Lindau associated pheochromocytomas
    Johan Kugelberg
    Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    World J Surg 38:724-32. 2014
    ..While SDHAF2 has been shown to be mutated in patients with paragangliomas (PGLs), SDHD mutations have been found both in patients with PCCs and in patients with PGLs...