- AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampusPontus Wasling
Department of Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
PLoS ONE 7:e34474. 2012..Our study shows that agonist binding to AMPARs is a sufficient triggering stimulus for the creation of AMPAR silent synapses at developing glutamate synapses...
- Long-term depression in the developing hippocampus: low induction threshold and synapse nonspecificityPontus Wasling
Institute of Physiology and Pharmacology, Goteborg University, SE 405 30 Goteborg, Sweden
J Neurosci 22:1823-30. 2002..They also support the notion that a brief rise in postsynaptic calcium can induce long-term potentiation (LTP) or LTD, a larger rise more likely to induce LTP, as well as that a prolonged modest increase produces selectively only LTD...
- Developmental changes in release properties of the CA3-CA1 glutamate synapse in rat hippocampusP Wasling
Institute of Physiology and Pharmacology, Department of Physiology, Goteborg University, Box 432, 405 30 Goteborg, Sweden
J Neurophysiol 92:2714-24. 2004....
- Creation of AMPA-silent synapses in the neonatal hippocampusMin Yi Xiao
Department of Physiology, Institute of Physiology and Pharmacology, Goteborg University, Box 432, 405 30 Goteborg, Sweden
Nat Neurosci 7:236-43. 2004..The AMPA silencing, possibly explained by a removal of postsynaptic AMPA receptors, could subsequently be reversed by paired presynaptic and postsynaptic activity...
- Modulation of low-frequency-induced synaptic depression in the developing CA3-CA1 hippocampal synapses by NMDA and metabotropic glutamate receptor activationJoakim Strandberg
Dept of Physiology, University of Gothenburg, Box 432, Medicinaregatan 11, 405 30 Gothenburg, Sweden
J Neurophysiol 101:2252-62. 2009..Our results seem in line with the notion that NMDARs and mGluRs may exert a bidirectional control on AMPA receptor recruitment to synapses...
- Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3Marta Pérez-Alcázar
Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation, The Sahlgrenska Academy at the University of Gothenburg, S 405 30 Gothenburg, Sweden Institute of Neuroscience and Physiology, Department of Physiology, The Sahlgrenska Academy at the University of Gothenburg, S 405 30 Gothenburg, Sweden
Exp Neurol 253:154-64. 2014..We conclude that C3 plays a role in the regulation of the number and function of glutamatergic synapses in the hippocampus and exerts negative effects on hippocampus-dependent cognitive performance. ..
- Synaptic retrogenesis and amyloid-beta in Alzheimer's diseasePontus Wasling
Department of Physiology, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
J Alzheimers Dis 16:1-14. 2009..Here, we review the literature on the possible physiological roles of Abeta and its precursor protein AbetaPP during development with special focus on electrophysiological findings...
- Antisecretory factor modulates GABAergic transmission in the rat hippocampusMalin Kim
Institute of Physiology and Pharmacology, Goteborg University, Sweden
Regul Pept 129:109-18. 2005..Our results identify AF as a neuromodulator and further raise the possibility that the hippocampus and AF are involved in a gut-brain loop controlling intestinal secretion and inflammation...