Research Topics
| Jonas WarringerSummaryCountry: Sweden Publications
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Detail Information
Publications
A Partial Least Squares based algorithm for parsimonious variable selectionTahir Mehmood
Biostatistics, Department of Chemistry, Biotechnology and Food Sciences, Norwegian University of Life Sciences, Norway
Algorithms Mol Biol 6:27. 2011..abstract:..
Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wideEun Hee Park
Laboratory of Gene Regulation and Development, Eunice K, Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
BMC Genomics 12:68. 2011....
Mining for genotype-phenotype relations in Saccharomyces using partial least squaresTahir Mehmood
Biostatistics, Department of Chemistry, Biotechnology and Food Sciences, Norwegian University of Life Sciences, Norway
BMC Bioinformatics 12:318. 2011..We introduce a methodology based on a BLAST approach for extracting information from genomic sequences and Soft- Thresholding Partial Least Squares (ST-PLS) for mapping genotype-phenotype relations...
Trait variation in yeast is defined by population historyJonas Warringer
Department of Cell and Molecular Biology, University of Gothenburg, Gothenburg, Sweden
PLoS Genet 7:e1002111. 2011..Overall, this study represents a step towards an in-depth understanding of the causal relationship between co-variation in ecology, selection pressure, natural traits, molecular mechanism, and alleles in a key model organism...
PROPHECY--a yeast phenome database, update 2006Luciano Fernandez Ricaud
Department of Cell and Molecular Biology, Lundberg Laboratory, Goteborg University, Medicinaregatan 9c SE 41390 Göteborg, Sweden
Nucleic Acids Res 35:D463-7. 2007..We have also extended the arsenal of data analysis tools to include dynamic visualization of phenotypes along individual chromosomes. PROPHECY is an initiative to enhance the growing field of phenome bioinformatics...
PROPHECY--a database for high-resolution phenomicsLuciano Fernandez-Ricaud
Department of Cell and Molecular Biology, Lundberg Laboratory, , , Sweden
Nucleic Acids Res 33:D369-73. 2005..PROPHECY is publicly accessible at http://prophecy.lundberg.gu.se...
The HOG pathway dictates the short-term translational response after hyperosmotic shockJonas Warringer
Department of Cell and Molecular Biology, Lundberg Laboratory, University of Gothenburg, S 40530 Göteborg, Sweden
Mol Biol Cell 21:3080-92. 2010..Our results show the importance of translational control for fine tuning of the adaptive responses...
Genetic pleiotropy in Saccharomyces cerevisiae quantified by high-resolution phenotypic profilingElke Ericson
Department of Cell and Molecular Biology, , Medicinaregatan 9C, Box 462, 40530, , Sweden
Mol Genet Genomics 275:605-14. 2006..Thus, the here reported features of pleiotropy both have implications on our understanding of evolutionary processes as well as the mechanisms underlying disease...
Sulfate assimilation mediates tellurite reduction and toxicity in Saccharomyces cerevisiaeLars Göran Ottosson
Department of Cell and Molecular Biology, University of Gothenburg, Sweden
Eukaryot Cell 9:1635-47. 2010..The results reported here represent a robust base from which to attack the mechanistic details of Te(IV) toxicity and reduction in a eukaryotic organism...
Quantitative proteomics of yeast post-Golgi vesicles reveals a discriminating role for Sro7p in protein secretionAnnabelle Forsmark
Department of Cell and Molecular Biology, Microbiology, University of Gothenburg, Box 462, SE 405 30 Gothenburg, Sweden
Traffic 12:740-53. 2011....
mRNA stability changes precede changes in steady-state mRNA amounts during hyperosmotic stressClaes Molin
Department of Cell and Molecular Biology, University of Gothenburg, Sweden
RNA 15:600-14. 2009..Conversely, stabilization of stress-repressed mRNAs permits their rapid accumulation in the recovery phase. Our results show that mRNA turnover is coordinated with transcriptional induction...
The Ashbya gossypii EF-1α promoter of the ubiquitously used MX cassettes is toxic to Saccharomyces cerevisiaeRoja Babazadeh
Department of Cell and Molecular Biology, University of Gothenburg, Gothenburg, Sweden
FEBS Lett 585:3907-13. 2011..Toxicity could be eliminated by promoter replacement or exclusion of the marker cassette. To our knowledge, this is the first report of toxicity caused by introduction of a heterologous promoter alone...
Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotypingJonathan Esguerra
Department of Cell and Molecular Biology, Goteborg University, 405 30 Goteborg, Sweden
RNA 14:649-56. 2008..Our data indicate that individual rRNA ribose methylations can play either distinct or general roles in the workings of the ribosome...
Evolutionary constraints on yeast protein sizeJonas Warringer
Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University Medicinaregatan 9c, 41390 Goteborg, Sweden
BMC Evol Biol 6:61. 2006..Data on yeast protein size was compared to global experimental data on protein expression, phenotypic pleiotropy, protein-protein interactions, protein evolutionary rate and biochemical classification...
Physiological importance and identification of novel targets for the N-terminal acetyltransferase NatBRobert Caesar
Department of Cell and Molecular Biology, Lundberg Laboratory, Goteborg University, Medicinaregatan 9C, 413 90 Goteborg, Sweden
Eukaryot Cell 5:368-78. 2006..By this procedure we predicted functional importance of the N-terminal acetylation for 31 proteins...
Robustness and fragility in the yeast high osmolarity glycerol (HOG) signal-transduction pathwayMarcus Krantz
Department of Cell and Molecular Biology, University of Gothenburg, Goteborg, Sweden
Mol Syst Biol 5:281. 2009..Thus, in vivo robustness data can be used to discriminate and improve mathematical models...
Involvement of yeast YOL151W/GRE2 in ergosterol metabolismJonas Warringer
Department of Cell and Molecular Biology, Lundberg Laboratory, Göteborg University Medicinaregatan 9c, 41390 Goteborg, Sweden
Yeast 23:389-98. 2006....
High-resolution yeast phenomics resolves different physiological features in the saline responseJonas Warringer
Department of Cell and Molecular Biology, Göteborg University Medicinaregatan 9c, 41390 Goteborg, Sweden
Proc Natl Acad Sci U S A 100:15724-9. 2003..In contrast, no correlation was found between gene dispensability and gene expression. It is proposed that high-resolution phenomics will be instrumental in systemwide descriptions of intragenomic functional networks...
The tumor suppressor homolog in fission yeast, myh1(+), displays a strong interaction with the checkpoint gene rad1(+)Kristina Jansson
Department of Cell and Molecular Biology, Lundberg Laboratory, Goteborg University, P O Box 462, Göteborg SE 405 30, Sweden
Mutat Res 644:48-55. 2008..Our results implicate fission yeast Myh1 in repair of a wider range of DNA damage than previously thought, and functionally link it to the checkpoint pathway...
Automated screening in environmental arrays allows analysis of quantitative phenotypic profiles in Saccharomyces cerevisiaeJonas Warringer
Department of Cell and Molecular Biology, Lundberg Laboratory, , Medicinaregatan 9C, , Sweden
Yeast 20:53-67. 2003..We propose the utilization of this methodology in large-scale screening of the complete collection of yeast deletion mutants...
