Bethany Van Guelpen

Summary

Country: Sweden

Publications

  1. pmc The association of education with body mass index and waist circumference in the EPIC-PANACEA study
    Silke Hermann
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    BMC Public Health 11:169. 2011
  2. pmc Low folate levels may protect against colorectal cancer
    B Van Guelpen
    Department of Medical Biosciences, Building 6M, 2nd Floor, Umea University, SE 901 85 Umea, Sweden
    Gut 55:1461-6. 2006
  3. ncbi request reprint Folate in colorectal cancer, prostate cancer and cardiovascular disease
    B Van Guelpen
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Scand J Clin Lab Invest 67:459-73. 2007
  4. doi request reprint One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study
    Bethany Van Guelpen
    Department of Medical Biosciences, Pathology, Umea University, Building 6M, 2nd Floor, 90185 Umea, Sweden
    Cancer Causes Control 21:557-66. 2010
  5. doi request reprint Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal function
    B Van Guelpen
    Department of Medical Biosciences, Umea University, Umea, Sweeden
    J Intern Med 266:182-95. 2009
  6. pmc High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis
    Maria L Wikberg
    Department of Medical Biosciences, Pathology, Umea University, Umea, SE 901 85, Sweden
    Tumour Biol 34:1013-20. 2013
  7. ncbi request reprint Plasma vitamin B12 concentrations and the risk of colorectal cancer: a nested case-referent study
    Anna M Dahlin
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Int J Cancer 122:2057-61. 2008
  8. ncbi request reprint Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: a prospective, nested case-referent study of plasma concentrations and dietary intake
    Bethany Van Guelpen
    Department of Medical Biosciences, Umea University Hospital, Umea, Sweden
    Stroke 36:1426-31. 2005
  9. ncbi request reprint Iron stores and HFE genotypes are not related to increased risk of ischemic stroke. A prospective nested case-referent study
    Kim Ekblom
    Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
    Cerebrovasc Dis 24:405-11. 2007
  10. doi request reprint Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective setting
    Kim Ekblom
    Unit of Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
    Dis Colon Rectum 55:337-44. 2012

Collaborators

Detail Information

Publications23

  1. pmc The association of education with body mass index and waist circumference in the EPIC-PANACEA study
    Silke Hermann
    Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
    BMC Public Health 11:169. 2011
    ..To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  2. pmc Low folate levels may protect against colorectal cancer
    B Van Guelpen
    Department of Medical Biosciences, Building 6M, 2nd Floor, Umea University, SE 901 85 Umea, Sweden
    Gut 55:1461-6. 2006
    ..The aim of this study was to relate prediagnostic plasma folate and homocysteine concentrations and the methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms to the risk of developing CRC...
  3. ncbi request reprint Folate in colorectal cancer, prostate cancer and cardiovascular disease
    B Van Guelpen
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Scand J Clin Lab Invest 67:459-73. 2007
  4. doi request reprint One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent study
    Bethany Van Guelpen
    Department of Medical Biosciences, Pathology, Umea University, Building 6M, 2nd Floor, 90185 Umea, Sweden
    Cancer Causes Control 21:557-66. 2010
    ..We related prediagnostic plasma folate, vitamin B12, and total homocysteine concentrations, and the MTHFR 677C>T and 1298A>C polymorphisms, to the risk of colorectal cancer with and without the CpG island methylator phenotype (CIMP)...
  5. doi request reprint Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal function
    B Van Guelpen
    Department of Medical Biosciences, Umea University, Umea, Sweeden
    J Intern Med 266:182-95. 2009
    ..To investigate the relationship between plasma folate, vitamin B12 and total homocysteine concentrations, dietary intake of folate and vitamins B12, B6 and B2, and the risk of first acute myocardial infarction (MI)...
  6. pmc High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis
    Maria L Wikberg
    Department of Medical Biosciences, Pathology, Umea University, Umea, SE 901 85, Sweden
    Tumour Biol 34:1013-20. 2013
    ..Stromal FAP expression is common in colorectal cancer, and we conclude that high FAP expression in the tumor center, but not the tumor front, is an independent negative prognostic factor...
  7. ncbi request reprint Plasma vitamin B12 concentrations and the risk of colorectal cancer: a nested case-referent study
    Anna M Dahlin
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Int J Cancer 122:2057-61. 2008
    ....
  8. ncbi request reprint Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: a prospective, nested case-referent study of plasma concentrations and dietary intake
    Bethany Van Guelpen
    Department of Medical Biosciences, Umea University Hospital, Umea, Sweden
    Stroke 36:1426-31. 2005
    ....
  9. ncbi request reprint Iron stores and HFE genotypes are not related to increased risk of ischemic stroke. A prospective nested case-referent study
    Kim Ekblom
    Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
    Cerebrovasc Dis 24:405-11. 2007
    ..The aim of this prospective study was to determine if iron status and HFE genotypes constitute risk factors for stroke...
  10. doi request reprint Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective setting
    Kim Ekblom
    Unit of Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
    Dis Colon Rectum 55:337-44. 2012
    ..High iron levels can increase the formation of noxious oxygen radicals, which are thought to promote carcinogenesis...
  11. pmc A traditional Sami diet score as a determinant of mortality in a general northern Swedish population
    Lena Maria Nilsson
    Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
    Int J Circumpolar Health 71:1-12. 2012
    ..To examine the relationship between "traditional Sami" dietary pattern and mortality in a general northern Swedish population...
  12. doi request reprint Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic stroke
    Johan Hultdin
    Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
    Clin Chem Lab Med 49:1555-62. 2011
    ....
  13. doi request reprint High SMAD4 levels appear in microsatellite instability and hypermethylated colon cancers, and indicate a better prognosis
    Martin Isaksson-Mettävainio
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Int J Cancer 131:779-88. 2012
    ..The novel findings that high SMAD4 expression predicts a better prognosis suggests that SMAD4 immunohistochemistry could constitute a prognostic marker in combination with CIMP and MSI screening status...
  14. doi request reprint Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumor
    Anna M Dahlin
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Mod Pathol 24:671-82. 2011
    ..In conclusion, patients whose tumors are highly infiltrated by T cells have a beneficial prognosis, regardless of MSI, whereas the role of CIMP status in this context is less clear...
  15. ncbi request reprint Plasma folate, vitamin B12, and homocysteine and prostate cancer risk: a prospective study
    Johan Hultdin
    Department of Medical Biosciences, Clinical Chemistry, Umea University Hospital, Umea, Sweden
    Int J Cancer 113:819-24. 2005
    ..On the contrary, vitamin B12, associated with an up to 3-fold increase in risk, and possibly also folate, may even stimulate prostate cancer development. These findings are novel and should be explored further in future studies...
  16. pmc Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion
    Maria L Henriksson
    Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
    Am J Pathol 178:1387-94. 2011
    ..Our findings provide evidence of a possible molecular mechanism involved in the cross talk between cancer cells and fibroblasts leading to cancer cell invasion...
  17. doi request reprint c-Met expression in primary tumors and their corresponding distant metastases
    Martin Isaksson-Mettävainio
    Department of Medical Biosciences and Pathology, Umea University, SE 901 85 Umea, Sweden
    Mol Med Report 1:787-90. 2008
    ..Additional studies of c-Met activation and signal transduction will increase our knowledge about the role of c-Met in colorectal cancer metastasis...
  18. ncbi request reprint Diet and lifestyle of the Sami of southern Lapland in the 1930s--1950s and today
    Lena Maria Nilsson
    Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
    Int J Circumpolar Health 70:301-18. 2011
    ....
  19. doi request reprint Consumption of filtered and boiled coffee and the risk of incident cancer: a prospective cohort study
    Lena Maria Nilsson
    Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
    Cancer Causes Control 21:1533-44. 2010
    ..Despite potentially relevant chemical differences between filtered and boiled coffee, this study is the first to investigate consumption in relation to the risk of incident cancer...
  20. doi request reprint Blood sample collection and patient identification demand improvement: a questionnaire study of preanalytical practices in hospital wards and laboratories
    Olof Wallin
    Department of Nursing, Umea University, Umea, Sweden
    Scand J Caring Sci 24:581-91. 2010
    ..Most important is the risk of misidentification of patients. Quality improvement of blood sample collection is clearly needed, particularly in hospital wards...
  21. doi request reprint Preanalytical venous blood sampling practices demand improvement--a survey of test-request management, test-tube labelling and information search procedures
    Olof Wallin
    Department of Medical Biosciences, Clinical Chemistry, Umea University, Umea, Sweden
    Clin Chim Acta 391:91-7. 2008
    ..In the present study, we aimed to survey preanalytical steps in venous blood sampling, prior to actual sample collection. These steps included test-request management and test-tube labelling, as well as information search procedures...
  22. ncbi request reprint Patient-centred care--preanalytical factors demand attention: a questionnaire study of venous blood sampling and specimen handling
    O Wallin
    Department of Medical Biosciences, Clinical Chemistry, Umea University, Umea, Sweden
    Scand J Clin Lab Invest 67:836-47. 2007
    ..This survey of preanalytical procedures was designed to identify sources of error and potential targets for quality improvement strategies...
  23. ncbi request reprint Modified Mediterranean diet and survival after myocardial infarction: the EPIC-Elderly study
    A Trichopoulou
    Department of Hygiene and Epidemiology, University of Athens, Medical School, 75 Mikras Asias St, 115 27, Athens, Greece
    Eur J Epidemiol 22:871-81. 2007
    ..A diet inspired by the Mediterranean pattern that can be easily adopted by Western populations is associated with substantial reduction of total mortality of coronary patients in the community...