Research Topics
Species | Bethany Van GuelpenSummaryCountry: Sweden Publications
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Detail Information
Publications
The association of education with body mass index and waist circumference in the EPIC-PANACEA studySilke Hermann
Division of Cancer Epidemiology, German Cancer Research Centre, Heidelberg, Germany
BMC Public Health 11:169. 2011..To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
One-carbon metabolism and CpG island methylator phenotype status in incident colorectal cancer: a nested case-referent studyBethany Van Guelpen
Department of Medical Biosciences, Pathology, Umea University, Building 6M, 2nd Floor, 90185 Umea, Sweden
Cancer Causes Control 21:557-66. 2010..We related prediagnostic plasma folate, vitamin B12, and total homocysteine concentrations, and the MTHFR 677C>T and 1298A>C polymorphisms, to the risk of colorectal cancer with and without the CpG island methylator phenotype (CIMP)...
Low folate levels may protect against colorectal cancerB Van Guelpen
Department of Medical Biosciences, Building 6M, 2nd Floor, Umea University, SE 901 85 Umea, Sweden
Gut 55:1461-6. 2006..The aim of this study was to relate prediagnostic plasma folate and homocysteine concentrations and the methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C polymorphisms to the risk of developing CRC...
Folate in colorectal cancer, prostate cancer and cardiovascular diseaseB Van Guelpen
Department of Medical Biosciences, Pathology, , Ume, Sweden
Scand J Clin Lab Invest 67:459-73. 2007
Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal functionB Van Guelpen
Department of Medical Biosciences, Umea University, Umea, Sweeden
J Intern Med 266:182-95. 2009..To investigate the relationship between plasma folate, vitamin B12 and total homocysteine concentrations, dietary intake of folate and vitamins B12, B6 and B2, and the risk of first acute myocardial infarction (MI)...
Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: a prospective, nested case-referent study of plasma concentrations and dietary intakeBethany Van Guelpen
Department of Medical Biosciences, Umea University Hospital, Umea, Sweden
Stroke 36:1426-31. 2005....
Plasma vitamin B12 concentrations and the risk of colorectal cancer: a nested case-referent studyAnna M Dahlin
Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
Int J Cancer 122:2057-61. 2008....
Iron stores and HFE genotypes are not related to increased risk of ischemic stroke. A prospective nested case-referent studyKim Ekblom
Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
Cerebrovasc Dis 24:405-11. 2007..The aim of this prospective study was to determine if iron status and HFE genotypes constitute risk factors for stroke...
A traditional Sami diet score as a determinant of mortality in a general northern Swedish populationLena Maria Nilsson
Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
Int J Circumpolar Health 71:1-12. 2012..To examine the relationship between "traditional Sami" dietary pattern and mortality in a general northern Swedish population...
Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes - evidence for an association with hemorrhagic strokeJohan Hultdin
Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
Clin Chem Lab Med 49:1555-62. 2011....
Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective settingKim Ekblom
Unit of Clinical Chemistry, Department of Medical Biosciences, Umea University, Umea, Sweden
Dis Colon Rectum 55:337-44. 2012..High iron levels can increase the formation of noxious oxygen radicals, which are thought to promote carcinogenesis...
High SMAD4 levels appear in microsatellite instability and hypermethylated colon cancers, and indicate a better prognosisMartin Isaksson-Mettävainio
Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
Int J Cancer 131:779-88. 2012..The novel findings that high SMAD4 expression predicts a better prognosis suggests that SMAD4 immunohistochemistry could constitute a prognostic marker in combination with CIMP and MSI screening status...
Colorectal cancer prognosis depends on T-cell infiltration and molecular characteristics of the tumorAnna M Dahlin
Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
Mod Pathol 24:671-82. 2011..In conclusion, patients whose tumors are highly infiltrated by T cells have a beneficial prognosis, regardless of MSI, whereas the role of CIMP status in this context is less clear...
Plasma folate, vitamin B12, and homocysteine and prostate cancer risk: a prospective studyJohan Hultdin
Department of Medical Biosciences, Clinical Chemistry, , Ume, Sweden
Int J Cancer 113:819-24. 2005..On the contrary, vitamin B12, associated with an up to 3-fold increase in risk, and possibly also folate, may even stimulate prostate cancer development. These findings are novel and should be explored further in future studies...
Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasionMaria L Henriksson
Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
Am J Pathol 178:1387-94. 2011..Our findings provide evidence of a possible molecular mechanism involved in the cross talk between cancer cells and fibroblasts leading to cancer cell invasion...
c-Met expression in primary tumors and their corresponding distant metastasesMartin Isaksson-Mettävainio
Department of Medical Biosciences and Pathology, Umea University, SE 901 85 Umea, Sweden
Mol Med Report 1:787-90. 2008..Additional studies of c-Met activation and signal transduction will increase our knowledge about the role of c-Met in colorectal cancer metastasis...
Diet and lifestyle of the Sami of southern Lapland in the 1930s--1950s and todayLena Maria Nilsson
Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
Int J Circumpolar Health 70:301-18. 2011....
Consumption of filtered and boiled coffee and the risk of incident cancer: a prospective cohort studyLena Maria Nilsson
Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
Cancer Causes Control 21:1533-44. 2010..Despite potentially relevant chemical differences between filtered and boiled coffee, this study is the first to investigate consumption in relation to the risk of incident cancer...
Blood sample collection and patient identification demand improvement: a questionnaire study of preanalytical practices in hospital wards and laboratoriesOlof Wallin
Department of Nursing, Umea University, Umea, Sweden
Scand J Caring Sci 24:581-91. 2010..Most important is the risk of misidentification of patients. Quality improvement of blood sample collection is clearly needed, particularly in hospital wards...
Preanalytical venous blood sampling practices demand improvement--a survey of test-request management, test-tube labelling and information search proceduresOlof Wallin
Department of Medical Biosciences, Clinical Chemistry, Umea University, Umea, Sweden
Clin Chim Acta 391:91-7. 2008..In the present study, we aimed to survey preanalytical steps in venous blood sampling, prior to actual sample collection. These steps included test-request management and test-tube labelling, as well as information search procedures...
Patient-centred care--preanalytical factors demand attention: a questionnaire study of venous blood sampling and specimen handlingO Wallin
Department of Medical Biosciences, Clinical Chemistry, Umea University, Umea, Sweden
Scand J Clin Lab Invest 67:836-47. 2007..This survey of preanalytical procedures was designed to identify sources of error and potential targets for quality improvement strategies...
Modified Mediterranean diet and survival after myocardial infarction: the EPIC-Elderly studyA Trichopoulou
Department of Hygiene and Epidemiology, University of Athens, Medical School, 75 Mikras Asias St, 115 27, Athens, Greece
Eur J Epidemiol 22:871-81. 2007..A diet inspired by the Mediterranean pattern that can be easily adopted by Western populations is associated with substantial reduction of total mortality of coronary patients in the community...
