Michael J Williams
Affiliation: Uppsala University
Williams M, Almén M, Fredriksson R, Schioth H. What model organisms and interactomics can reveal about the genetics of human obesity. Cell Mol Life Sci. 2012;69:3819-34 pubmed publisher
Krishnan A, Dnyansagar R, AlmÃ©n M, Williams M, Fredriksson R, Manoj N, et al
. The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals. BMC Evol Biol. 2014;14:270 pubmed publisher
..In summary, this study provides a framework to perform future experimental and comparative studies to further verify and understand the roles of GPCRs that predates the divergence of bilaterian and eumetazoan lineages. ..
Eriksson A, Williams M, Voisin S, Hansson I, Krishnan A, Philippot G, et al
. Implication of coronin 7 in body weight regulation in humans, mice and flies. BMC Neurosci. 2015;16:13 pubmed publisher
..We conclude that coronin 7 is involved in the regulation of energy homeostasis and this role stems, to some degree, from the effect on feeding for calories and reward. ..
Krishnan A, Mustafa A, AlmÃ©n M, Fredriksson R, Williams M, SchiÃ¶th H. Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families. Mol Phylogenet Evol. 2015;91:27-40 pubmed publisher
..Our robust classification/hierarchy is essential to further understand the differential roles of GPCR/G protein mediated intracellular signaling system across various metazoan lineages. ..
Cinege G, ZsÃ¡mboki J, Vidal Quadras M, Uv A, CsordÃ¡s G, Honti V, et al
. Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. Insect Biochem Mol Biol. 2017;87:45-54 pubmed publisher
..Here we show that, unlike the Nimrod candidates, the Vajk proteins are expressed in cuticular structures of the late embryo and the late pupa, indicating that they contribute to cuticular barrier functions. ..