U Uhlin

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi request reprint Glycyl radical enzymes: a conservative structural basis for radicals
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Biomedical Center, Box 590, Uppsala, S 751 24, Sweden
    Structure 7:R257-62. 1999
  2. ncbi request reprint Structure and function of the radical enzyme ribonucleotide reductase
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Box 590, S 751 24, Uppsala, Sweden
    Prog Biophys Mol Biol 77:177-268. 2001
  3. ncbi request reprint Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding
    M Eriksson
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    Structure 5:1077-92. 1997
  4. ncbi request reprint Crystallization and crystallographic investigations of ribonucleotide reductase protein R1 from Escherichia coli
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    FEBS Lett 336:148-52. 1993
  5. ncbi request reprint Structure of ribonucleotide reductase protein R1
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala
    Nature 370:533-9. 1994

Collaborators

  • M Fontecave
  • H Eklund
  • M Eriksson
  • D T Logan
  • M Farnegardh
  • P Nordlund
  • K Regnstrom
  • S Ramaswamy
  • M Ekberg
  • B M Sjoberg

Detail Information

Publications5

  1. ncbi request reprint Glycyl radical enzymes: a conservative structural basis for radicals
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Biomedical Center, Box 590, Uppsala, S 751 24, Sweden
    Structure 7:R257-62. 1999
    ..This work provides new insights into the structure and chemistry of glycyl radical sites...
  2. ncbi request reprint Structure and function of the radical enzyme ribonucleotide reductase
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Box 590, S 751 24, Uppsala, Sweden
    Prog Biophys Mol Biol 77:177-268. 2001
    ..RNRs are also allosterically regulated, for which the structural molecular background is now starting to be revealed...
  3. ncbi request reprint Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding
    M Eriksson
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    Structure 5:1077-92. 1997
    ..Our aim has been to crystallographically demonstrate substrate binding and to locate the two effector-binding sites...
  4. ncbi request reprint Crystallization and crystallographic investigations of ribonucleotide reductase protein R1 from Escherichia coli
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    FEBS Lett 336:148-52. 1993
    ..The dimer is thin in the middle around the molecular two-fold axis. The subunit is shaped like a bowl, probably with the active site in its center...
  5. ncbi request reprint Structure of ribonucleotide reductase protein R1
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala
    Nature 370:533-9. 1994
    ..The fifth cysteine, in a loop in the centre of the barrel, is positioned to initiate the radical reaction...