U Uhlin

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi Glycyl radical enzymes: a conservative structural basis for radicals
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Biomedical Center, Box 590, Uppsala, S 751 24, Sweden
    Structure 7:R257-62. 1999
  2. ncbi Structure and function of the radical enzyme ribonucleotide reductase
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Box 590, S 751 24, Uppsala, Sweden
    Prog Biophys Mol Biol 77:177-268. 2001
  3. ncbi Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding
    M Eriksson
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    Structure 5:1077-92. 1997
  4. ncbi Crystallization and crystallographic investigations of ribonucleotide reductase protein R1 from Escherichia coli
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    FEBS Lett 336:148-52. 1993
  5. ncbi Structure of ribonucleotide reductase protein R1
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala
    Nature 370:533-9. 1994

Collaborators

  • M Fontecave
  • H Eklund
  • M Eriksson
  • D T Logan
  • P Nordlund
  • M Farnegardh
  • M Ekberg
  • S Ramaswamy
  • K Regnstrom
  • B M Sjoberg

Detail Information

Publications5

  1. ncbi Glycyl radical enzymes: a conservative structural basis for radicals
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Biomedical Center, Box 590, Uppsala, S 751 24, Sweden
    Structure 7:R257-62. 1999
    ..This work provides new insights into the structure and chemistry of glycyl radical sites...
  2. ncbi Structure and function of the radical enzyme ribonucleotide reductase
    H Eklund
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Box 590, S 751 24, Uppsala, Sweden
    Prog Biophys Mol Biol 77:177-268. 2001
    ..RNRs are also allosterically regulated, for which the structural molecular background is now starting to be revealed...
  3. ncbi Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding
    M Eriksson
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    Structure 5:1077-92. 1997
    ..Our aim has been to crystallographically demonstrate substrate binding and to locate the two effector-binding sites...
  4. ncbi Crystallization and crystallographic investigations of ribonucleotide reductase protein R1 from Escherichia coli
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center, Sweden
    FEBS Lett 336:148-52. 1993
    ..The dimer is thin in the middle around the molecular two-fold axis. The subunit is shaped like a bowl, probably with the active site in its center...
  5. ncbi Structure of ribonucleotide reductase protein R1
    U Uhlin
    Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala
    Nature 370:533-9. 1994
    ..The fifth cysteine, in a loop in the centre of the barrel, is positioned to initiate the radical reaction...