B Tyrberg

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Endocrinology 137:5694-9. 1996
  2. ncbi Human islets in mixed islet grafts protect mouse pancreatic beta-cells from alloxan toxicity
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Pharmacol Toxicol 85:269-75. 1999
  3. ncbi Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets: effects of the ob gene and compensatory growth of the implantation organ
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Diabetes 50:301-7. 2001
  4. ncbi Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Uppsala, SE 751 23, Sweden
    Gen Comp Endocrinol 122:238-51. 2001
  5. ncbi Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death
    C A Delaney
    Department of Medical Cell Biology, Uppsala University, Sweden Carol
    FEBS Lett 394:300-6. 1996
  6. ncbi Microcirculation of human pancreatic islets transplanted under the renal capsule of nude mice
    L Jansson
    Department of Medical Cell Biology, Uppsala University, Sweden
    Transplantation 72:730-2. 2001
  7. ncbi Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes
    M Flodstrom
    Department of Medical Cell Biology, Uppsala University, Sweden
    Diabetes 48:706-13. 1999

Collaborators

Detail Information

Publications7

  1. ncbi Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Endocrinology 137:5694-9. 1996
    ..Moreover, beta-cells from adult human donors respond with increased proliferation to glucose in vitro and show a decreased proliferation in vivo with increasing donor age...
  2. ncbi Human islets in mixed islet grafts protect mouse pancreatic beta-cells from alloxan toxicity
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Pharmacol Toxicol 85:269-75. 1999
    ..Alloxan-insensitive human islets protect mouse beta-cells against alloxan-induced lesions, suggesting that yet to be identified extracellular factors are involved in human islet resistance to alloxan toxicity...
  3. ncbi Stimulated endocrine cell proliferation and differentiation in transplanted human pancreatic islets: effects of the ob gene and compensatory growth of the implantation organ
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Sweden
    Diabetes 50:301-7. 2001
    ..Altogether, these data and previous results from our laboratory suggest that human beta-cell neogenesis becomes more dependent on differentiation and less dependent on proliferation with increasing age...
  4. ncbi Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan
    B Tyrberg
    Department of Medical Cell Biology, Uppsala University, Uppsala, SE 751 23, Sweden
    Gen Comp Endocrinol 122:238-51. 2001
    ..Finally, no correlation between high alloxan sensitivity and high lysosomal enzyme activity was found. Thus, the beta-cell lysosomes are hardly specific targets for alloxan...
  5. ncbi Sensitivity of human pancreatic islets to peroxynitrite-induced cell dysfunction and death
    C A Delaney
    Department of Medical Cell Biology, Uppsala University, Sweden Carol
    FEBS Lett 394:300-6. 1996
    ..This study demonstrates for the first time that cultured human pancreatic islets are susceptible to the noxious effects of peroxynitrite...
  6. ncbi Microcirculation of human pancreatic islets transplanted under the renal capsule of nude mice
    L Jansson
    Department of Medical Cell Biology, Uppsala University, Sweden
    Transplantation 72:730-2. 2001
    ..The aim was to measure the capillary blood pressure in transplanted human islets...
  7. ncbi Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes
    M Flodstrom
    Department of Medical Cell Biology, Uppsala University, Sweden
    Diabetes 48:706-13. 1999
    ..In conclusion, the present study provides evidence that iNOS may contribute to beta-cell damage after exposure to IL-1beta in vitro and treatment with MLDS in vivo...