Affiliation: Uppsala University
- Stroke and plasma markers of milk fat intake--a prospective nested case-control studyEva Warensjo
Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden
Nutr J 8:21. 2009..The fatty acids 15:0 and 17:0 of plasma lipids are biomarkers of milk fat intake. The aim of the present study was to evaluate the risk of a first-ever stroke in relation to the plasma milk fat biomarkers...
- Conjugated linoleic acid supplementation in humans--metabolic effectsA Smedman
Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Sweden
Lipids 36:773-81. 2001..These results suggest that supplementation with CLA may reduce the proportion of body fat in humans and that CLA affects fatty acid metabolism. No effects on body weight, serum lipids, glucose metabolism, or PAI-1 were seen...
- Conjugated linoleic acid increased C-reactive protein in human subjectsAnnika Smedman
Unit for Clinical Nutrition Research, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
Br J Nutr 94:791-5. 2005..CLA supplementation increased levels of C-reactive protein (P=0.003) compared with the control group. However, no changes in TNF-alpha, TNF-alpha receptors 1 and 2, and vascular cell adhesion molecule-1 were detected...
- Conjugated linoleic acid induces lipid peroxidation in humansS Basu
Section of Geriatrics Clinical Nutrition Research, Faculty of Medicine, Uppsala University, Box 609, SE 751 25, Uppsala, Sweden
FEBS Lett 468:33-6. 2000..Thus, CLA may induce both non-enzymatic and enzymatic lipid peroxidation in vivo. Further studies of the mechanism behind, and the possible consequences of, the increased lipid peroxidation after CLA supplementation are urgently needed...
- Metabolic effects of conjugated linoleic acid in humans: the Swedish experienceUlf Riserus
Unit for Clinical Nutrition Research, Department of Public Health and Caring Sciences, University of Uppsala, Uppsala, Sweden
Am J Clin Nutr 79:1146S-1148S. 2004..In addition, CLA markedly elevated lipid peroxidation. Thus, the metabolic effects of CLA in humans seem complex, and further studies, especially of specific isomers and of longer duration, are needed...
- Plasminogen activator inhibitor-1 and relations to fatty acid composition in the diet and in serum cholesterol estersL Byberg
Sections of Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
Arterioscler Thromb Vasc Biol 21:2086-92. 2001..The associations present between PAI-1 activity and the fatty acid proportions in serum cholesterol esters are partly influenced by metabolic syndrome-related factors...
- Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitorAnnika Smedman
Unit for Clinical Nutrition Research, Department for Public Health and Caring Sciences/Geriatrics, Uppsala University, PO Box 609, S-751 25 Uppsala, Sweden
Clin Sci (Lond) 106:67-73. 2004..The CLA-induced production of PGF2alpha metabolites is probably partially mediated by COX-2. Levels of the induced lipid peroxidation may be dependent on the isomeric property of CLA...