Research Topics
| J RonnelidSummaryAffiliation: Uppsala University Country: Sweden Publications
| Collaborators
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Detail Information
Publications
Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritisHeidi Kokkonen
Departments of Public Health and Clinical Medicine Rheumatology, Umea University, SE 90185 Umeå, Sweden
Arthritis Res Ther 13:R13. 2011....
Immune complexes from rheumatoid arthritis synovial fluid induce FcgammaRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-alpha by peripheral blood mononuclear cellsLinda Mathsson
Unit of Clinical Immunology, Uppsala University, Uppsala, Sweden
Arthritis Res Ther 8:R64. 2006..Suppression of monocytes/macrophages in RA joints or blockade of the primate-specific activating FcgammaRIIa receptor might be ways to reduce IC-induced TNF-alpha production in the joints of seropositive RA patients...
Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FcgammaRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLEJ Ronnelid
Department of Clinical Immunology, Rudbeck Laboratory, University Hospital, Uppsala University, S 751 85 Uppsala, Sweden
Ann Rheum Dis 62:37-42. 2003..These immune complexes can then stimulate cellular reactions through Fc and complement receptors...
[Antibodies against citrullinated proteins--a breakthrough in rheumatologic diagnostics]Johan Ronnelid
Enheten för klinisk immunologi, klinisk immunologi och transfusionsmedicin, Uppsala universitet Akademiska sjukhuset
Lakartidningen 101:4092-6. 2004..Due to its considerably higher specificity, the authors recommend that anti-CP antibody analysis should replace the RF test in primary healthcare when investigating cases of clinically suspect RA...
Longitudinal analysis of citrullinated protein/peptide antibodies (anti-CP) during 5 year follow up in early rheumatoid arthritis: anti-CP status predicts worse disease activity and greater radiological progressionJ Ronnelid
Unit of Clinical Immunology, Rudbeck Laboratory C5, SE 75185 Uppsala, Sweden
Ann Rheum Dis 64:1744-9. 2005....
Immune complex-mediated cytokine production is regulated by classical complement activation both in vivo and in vitroJohan Ronnelid
Unit of Clinical Immunology, Uppsala University, Uppsala, Sweden
Adv Exp Med Biol 632:187-201. 2008..If IC are formed in vivo, the results have to be interpreted in the context of classical complement activation in vivo as well as the occurrence of IC-associated autoantibodies at the time of serum sampling...
Use of a commercial line blot assay as a screening test for autoantibodies in inflammatory myopathiesJohan Ronnelid
Unit of Clinical Immunology, Uppsala University and Uppsala University Hospital, SE 75185 Uppsala, Sweden
Autoimmun Rev 9:58-61. 2009..To evaluate the clinical utility of a commercial immunoblot assay for the detection of myositis-specific autoantibodies...
Cytokine induction by circulating immune complexes and signs of in-vivo complement activation in systemic lupus erythematosus are associated with the occurrence of anti-Sjögren's syndrome A antibodiesL Mathsson
Department of Clinical Immunology, Uppsala University, Uppsala, Sweden
Clin Exp Immunol 147:513-20. 2007..Our results indicate that anti-SSA and possibly anti-SSB antibodies influence IC formation and subsequent IC-induced cytokine induction, and that they thereby participate in the inflammatory process in active SLE...
Autoantibodies associated with RNA are more enriched than anti-dsDNA antibodies in circulating immune complexes in SLEE Ahlin
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
Lupus 21:586-95. 2012..These finding have implications in understanding mechanisms of differential autoantibody accumulation in target organs in SLE...
