Ulf Riserus

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi request reprint Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome
    Ulf Riserus
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Diabetes Care 25:1516-21. 2002
  2. ncbi request reprint Long-term predictors of insulin resistance: role of lifestyle and metabolic factors in middle-aged men
    Ulf Riserus
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala Science Park, 751 85 Uppsala, Sweden
    Diabetes Care 30:2928-33. 2007
  3. ncbi request reprint [Trans fats not a big problem in Sweden. But the food industry should eliminate them completely from all products]
    Ulf Riserus
    Lakartidningen 104:658-9. 2007
  4. doi request reprint Fatty acids and insulin sensitivity
    Ulf Riserus
    Clinical Nutrition and Metabolism, Uppsala University, Faculty of Medicine, Uppsala, Sweden
    Curr Opin Clin Nutr Metab Care 11:100-5. 2008
  5. ncbi request reprint Trans fatty acids and insulin resistance
    Ulf Riserus
    Clinical Nutrition and Metabolism, Uppsala University, Faculty of Medicine, Sweden
    Atheroscler Suppl 7:37-9. 2006
  6. ncbi request reprint Alcohol intake, insulin resistance, and abdominal obesity in elderly men
    Ulf Riserus
    Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism Geriatrics, Uppsala Science Park, 751 85 Uppsala, Sweden
    Obesity (Silver Spring) 15:1766-73. 2007
  7. pmc Dietary fats and prevention of type 2 diabetes
    Ulf Riserus
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Faculty of Medicine, Uppsala University, Uppsala Science Park, 75185 Uppsala, Sweden
    Prog Lipid Res 48:44-51. 2009
  8. ncbi request reprint Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men
    Ulf Riserus
    Clinical Nutrition Research Unit, Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Box 609, 75125 Uppsala, Sweden
    Am J Clin Nutr 80:279-83. 2004
  9. ncbi request reprint Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance
    Ulf Riserus
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Circulation 106:1925-9. 2002
  10. pmc Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study
    Elisabet Nerpin
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, SE 751 85, Uppsala, Sweden
    BMC Res Notes 5:537. 2012

Detail Information

Publications42

  1. ncbi request reprint Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome
    Ulf Riserus
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Diabetes Care 25:1516-21. 2002
    ..The aim of this study was to investigate whether t10c12 CLA or a commercial CLA mixture could improve insulin sensitivity, lipid metabolism, or body composition in obese men with signs of the metabolic syndrome...
  2. ncbi request reprint Long-term predictors of insulin resistance: role of lifestyle and metabolic factors in middle-aged men
    Ulf Riserus
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala Science Park, 751 85 Uppsala, Sweden
    Diabetes Care 30:2928-33. 2007
    ..Few researchers have measured insulin sensitivity directly and compared different metabolic and lifestyle predictors in a large population...
  3. ncbi request reprint [Trans fats not a big problem in Sweden. But the food industry should eliminate them completely from all products]
    Ulf Riserus
    Lakartidningen 104:658-9. 2007
  4. doi request reprint Fatty acids and insulin sensitivity
    Ulf Riserus
    Clinical Nutrition and Metabolism, Uppsala University, Faculty of Medicine, Uppsala, Sweden
    Curr Opin Clin Nutr Metab Care 11:100-5. 2008
    ..The effects of different types of dietary fatty acids on insulin sensitivity in humans are discussed, with focus on recent controlled studies...
  5. ncbi request reprint Trans fatty acids and insulin resistance
    Ulf Riserus
    Clinical Nutrition and Metabolism, Uppsala University, Faculty of Medicine, Sweden
    Atheroscler Suppl 7:37-9. 2006
    ..Large controlled trials have been required to demonstrate adverse effects of saturated fat on insulin sensitivity, and similar efforts will probably be needed to clarify the effect of TFA on insulin sensitivity...
  6. ncbi request reprint Alcohol intake, insulin resistance, and abdominal obesity in elderly men
    Ulf Riserus
    Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism Geriatrics, Uppsala Science Park, 751 85 Uppsala, Sweden
    Obesity (Silver Spring) 15:1766-73. 2007
    ..Insulin resistance, insulin secretion, and abdominal obesity are major predictors of diabetes, but the links with alcohol intake remain contradictory because of limited data...
  7. pmc Dietary fats and prevention of type 2 diabetes
    Ulf Riserus
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Faculty of Medicine, Uppsala University, Uppsala Science Park, 75185 Uppsala, Sweden
    Prog Lipid Res 48:44-51. 2009
    ..Consumption of partially hydrogenated fats should be minimized. Additional controlled, long-term studies are needed to improve our knowledge on the optimal proportion of different types of fats to prevent diabetes...
  8. ncbi request reprint Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men
    Ulf Riserus
    Clinical Nutrition Research Unit, Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Box 609, 75125 Uppsala, Sweden
    Am J Clin Nutr 80:279-83. 2004
    ..Because c9,t11 CLA is the predominant CLA isomer in foods and is included in dietary weight-loss products, it is important to conduct randomized controlled studies that use c9,t11 CLA preparations...
  9. ncbi request reprint Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance
    Ulf Riserus
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Circulation 106:1925-9. 2002
    ..The aim of the present study was to examine whether CLA has isomer-specific effects on oxidative stress or inflammatory biomarkers and to investigate the relationship between these factors and induced insulin resistance...
  10. pmc Inflammation, oxidative stress, glomerular filtration rate, and albuminuria in elderly men: a cross-sectional study
    Elisabet Nerpin
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, SE 751 85, Uppsala, Sweden
    BMC Res Notes 5:537. 2012
    ....
  11. ncbi request reprint Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: a population-based prospective study
    Eva Warensjo
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Am J Clin Nutr 88:203-9. 2008
    ..Desaturase indexes, as markers of endogenous fatty acid desaturation, and a characteristic serum fatty acid (FA) composition are related to cardiovascular and metabolic diseases, but the relation to mortality is poorly investigated...
  12. ncbi request reprint Metabolic effects of conjugated linoleic acid in humans: the Swedish experience
    Ulf Riserus
    Unit for Clinical Nutrition Research, Department of Public Health and Caring Sciences, University of Uppsala, Uppsala, Sweden
    Am J Clin Nutr 79:1146S-1148S. 2004
    ..In addition, CLA markedly elevated lipid peroxidation. Thus, the metabolic effects of CLA in humans seem complex, and further studies, especially of specific isomers and of longer duration, are needed...
  13. pmc Serum cathepsin S is associated with decreased insulin sensitivity and the development of type 2 diabetes in a community-based cohort of elderly men
    Elisabeth Jobs
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    Diabetes Care 36:163-5. 2013
    ..To investigate associations between serum cathepsin S, impaired insulin sensitivity, defective insulin secretion, and diabetes risk in a community-based sample of elderly men without diabetes...
  14. pmc Sagittal abdominal diameter as a marker of inflammation and insulin resistance among immigrant women from the Middle East and native Swedish women: a cross-sectional study
    Helena Petersson
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala, Sweden
    Cardiovasc Diabetol 6:10. 2007
    ..To investigate the predictive role of SAD compared to other anthropometric measures, we examined a random sample of native-Swedes and immigrant women from the Middle East living in Sweden...
  15. ncbi request reprint Serum fatty acid composition and indices of stearoyl-CoA desaturase activity are associated with systemic inflammation: longitudinal analyses in middle-aged men
    Helena Petersson
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, 751 85 Uppsala, Sweden
    Br J Nutr 99:1186-9. 2008
    ....
  16. ncbi request reprint Relationships between serum fatty acid composition and multiple markers of inflammation and endothelial function in an elderly population
    Helena Petersson
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, 75185 Uppsala, Sweden
    Atherosclerosis 203:298-303. 2009
    ..This study investigates the associations between serum FA composition, including SCD-1 index, and various inflammatory and endothelial function markers...
  17. pmc Adipose tissue stearoyl-CoA desaturase 1 index is increased and linoleic acid is decreased in obesity-prone rats fed a high-fat diet
    Jonathan Cedernaes
    Department of Neuroscience, Uppsala University, BMC, Uppsala, Sweden
    Lipids Health Dis 12:2. 2013
    ..Our aim was to test whether desaturase activity and FA composition are linked to an obese phenotype in rats that are either obesity prone (OP) or resistant (OR) on a high-fat diet (HFD)...
  18. doi request reprint Serum fatty acid composition and insulin resistance are independently associated with liver fat markers in elderly men
    Helena Petersson
    Department of Public Health and Caring Sciences Clinical Nutrition and Metabolism, Uppsala University, Uppsala Science Park, 75185 Uppsala, Sweden
    Diabetes Res Clin Pract 87:379-84. 2010
    ..To investigate the relationships of serum fatty acid (FA) composition and estimated desaturase activities with the liver fat marker alanine aminotransferase (ALT)...
  19. doi request reprint The combined contribution of albuminuria and glomerular filtration rate to the prediction of cardiovascular mortality in elderly men
    Elisabet Nerpin
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Nephrol Dial Transplant 26:2820-7. 2011
    ..Yet, data on whether the combined addition of albuminuria and estimated glomerular filtration rate (eGFR) improves cardiovascular risk prediction in individuals without CVD in the community is scarce...
  20. ncbi request reprint Low-grade albuminuria and the incidence of heart failure in a community-based cohort of elderly men
    Erik Ingelsson
    Section of Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, Uppsala, Sweden
    Eur Heart J 28:1739-45. 2007
    ..To investigate associations of urinary albumin excretion rate (UAER) and heart failure (HF) incidence in a community-based sample...
  21. doi request reprint Effects of dietary fat modification on oxidative stress and inflammatory markers in the LIPGENE study
    Helena Petersson
    Department of Public Health and Caring Sciences Clinical Nutrition and Metabolism, Uppsala University, Uppsala Science Park, 75185 Uppsala, Sweden
    Br J Nutr 104:1357-62. 2010
    ..In conclusion, a 12-week dietary fat modification did not affect the investigated markers of oxidative stress and inflammation among subjects with the MetS in the LIPGENE study...
  22. doi request reprint Association between glomerular filtration rate and endothelial function in an elderly community cohort
    Elisabet Nerpin
    Department of Public Health and Caring Sciences Geriatrics, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Atherosclerosis 224:242-6. 2012
    ..However, the association between glomerular filtration rate and endothelial function in the community is unclear and needs to be investigated in the general population...
  23. ncbi request reprint Antioxidant intake, oxidative stress and inflammation among immigrant women from the Middle East living in Sweden: associations with cardiovascular risk factors
    Achraf Daryani
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, 751 85 Uppsala, Sweden
    Nutr Metab Cardiovasc Dis 17:748-56. 2007
    ..We also investigated relationships between F(2)-isoprostanes, CRP and cardiovascular risk factors...
  24. doi request reprint Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial
    Helena Bjermo
    Department of Public Health, Uppsala University, Uppsala, Sweden
    Am J Clin Nutr 95:1003-12. 2012
    ..Replacing SFAs with vegetable PUFAs has cardiometabolic benefits, but the effects on liver fat are unknown. Increased dietary n-6 PUFAs have, however, also been proposed to promote inflammation-a yet unproven theory...
  25. pmc Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance
    Eva Warensjo
    Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden
    Lipids Health Dis 8:37. 2009
    ..D5D in PL was inversely related to obesity and insulin resistance, whereas D6D index showed positive associations...
  26. ncbi request reprint Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity
    Eva Warensjo
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, 751 85 Uppsala, Sweden
    Obesity (Silver Spring) 15:1732-40. 2007
    ..Further, SCD1-deficent mice are protected against obesity and insulin resistance. We hypothesized that genetic polymorphisms in the SCD1 gene would be associated with obesity, insulin sensitivity, and estimated SCD activity in humans...
  27. ncbi request reprint Sagittal abdominal diameter is a strong anthropometric marker of insulin resistance and hyperproinsulinemia in obese men
    Ulf Riserus
    Clinical Nutrition Research Unit, Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Diabetes Care 27:2041-6. 2004
    ..Sagittal abdominal diameter (SAD) or "supine abdominal height" is a simple anthropometric measure previously shown to predict mortality in men, but its association with insulin resistance and hyperproinsulinemia is unknown...
  28. doi request reprint Effects of saturated and unsaturated fatty acids on estimated desaturase activities during a controlled dietary intervention
    Eva Warensjo
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Nutr Metab Cardiovasc Dis 18:683-90. 2008
    ..Data on how the markers of desaturase activities are modified by changes in dietary fat quality are lacking and therefore warrant examination...
  29. pmc Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly
    Olga E Titova
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Age (Dordr) 35:1495-505. 2013
    ..These cross-sectional findings suggest that dietary intake of EPA and DHA may be linked to improved cognitive health in late life but must be confirmed in patient studies...
  30. ncbi request reprint CLA and body weight regulation in humans
    Ulf Riserus
    Unit for Clinical Nutrition Research, Department of Public Health and Caring Sciences, University of Uppsala, Uppsala, Sweden
    Lipids 38:133-7. 2003
    ..In addition, CLA markedly elevated lipid peroxidation. Thus, the metabolic effects of CLA in humans seem complex; further studies, especially of isomer-specific effects and for longer time periods, are warranted...
  31. doi request reprint Role of hepatic desaturases in obesity-related metabolic disorders
    Helena Bjermo
    Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden
    Curr Opin Clin Nutr Metab Care 13:703-8. 2010
    ..This review aims to address the latest research on hepatic desaturases and metabolic disorders, with focus on stearoyl-CoA desaturase-1 (SCD-1) indices in observational studies...
  32. doi request reprint Association between serum cathepsin S and mortality in older adults
    Elisabeth Jobs
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    JAMA 306:1113-21. 2011
    ..However, prospective data concerning a potential association between circulating cathepsin S levels and mortality are lacking...
  33. ncbi request reprint Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans
    Fredrik Rosqvist
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Diabetes 63:2356-68. 2014
    ..In conclusion, overeating SFAs promotes hepatic and visceral fat storage, whereas excess energy from PUFAs may instead promote lean tissue in healthy humans. ..
  34. doi request reprint An environmental wide association study (EWAS) approach to the metabolic syndrome
    P Monica Lind
    Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
    Environ Int 55:1-8. 2013
    ..Environmental contaminants have previously been linked to components of the Metabolic Syndrome (MetS). However, exposure to environmental contaminants is in part determined by various lifestyle factors...
  35. ncbi request reprint Kidney injury molecule (KIM)-1 is associated with insulin resistance: Results from two community-based studies of elderly individuals
    Axel C Carlsson
    Centre for Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden Electronic address
    Diabetes Res Clin Pract 103:516-21. 2014
    ..The role of insulin resistance in the development of kidney tubular damage is not previously reported. Thus, we aimed to investigate the associations between insulin sensitivity (assessed by HOMA) and urinary KIM-1...
  36. pmc The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924
    Josefin A Jacobsson
    Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden
    BMC Med Genet 10:131. 2009
    ..Here we set out to examine the association of the FTO variant rs9939609 with BMI in a 32 year follow up study of men born 1920-1924. Moreover, we analyzed the effect of physical activity on the different genotypes...
  37. ncbi request reprint A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men
    Johan Arnlov
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Am Heart J 149:902-7. 2005
    ..The novel myocardial performance index (MPI, also denoted as Tei-Doppler index) has been suggested to reflect both left ventricular (LV) systolic and diastolic function...
  38. pmc Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans
    Pawel K Olszewski
    Functional Pharmacology Unit, Department of Neuroscience, Uppsala University, Uppsala, Sweden
    PLoS Genet 8:e1002568. 2012
    ..Our study emphasizes the importance of neural mechanisms in body weight control and points out NBEA as a potential risk gene in human obesity...
  39. ncbi request reprint Myocardial performance index, a Doppler-derived index of global left ventricular function, predicts congestive heart failure in elderly men
    Johan Arnlov
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    Eur Heart J 25:2220-5. 2004
    ..Myocardial performance index (MPI, also denoted TEI-Doppler index) reflects both left ventricular (LV) systolic and diastolic function...
  40. pmc Clinical Correlates of Insulin Sensitivity and Its Association with Mortality among Men with CKD Stages 3 and 4
    Hong Xu
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden, Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China, Division of Nephrology, Peking University Shenzhen Hospital, Peking University, Shenzhen, China, Department of Public Health and Caring Sciences, Section of Geriatrics, and, Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden, School of Health and Social Studies, Dalarna University, Falun, Sweden, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    Clin J Am Soc Nephrol 9:690-7. 2014
    ..CKD patients have impaired insulin sensitivity, but the clinical correlates and outcome associations of impaired insulin sensitivity in this vulnerable population are not well defined...
  41. doi request reprint Hypertriglyceridemic waist phenotype is associated with decreased insulin sensitivity and incident diabetes in elderly men
    Axel C Carlsson
    Center for Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden Department of Public Health and Caring Sciences Section of Geriatrics Uppsala University, Uppsala, Sweden
    Obesity (Silver Spring) 22:526-9. 2014
    ....