Joel Petersson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi request reprint Dietary nitrate increases gastric mucosal blood flow and mucosal defense
    Joel Petersson
    Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Gastrointest Liver Physiol 292:G718-24. 2007
  2. doi request reprint Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash
    Joel Petersson
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Free Radic Biol Med 46:1068-75. 2009
  3. pmc iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats
    Olof Schreiber
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    PLoS ONE 8:e71843. 2013
  4. pmc Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction
    Johan Dicksved
    Department of Microbiology, Uppsala BioCenter, Swedish University of Agricultural Sciences, Uppsala, Sweden
    PLoS ONE 7:e46399. 2012
  5. pmc Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
    HåKan Björne H
    Department of Anesthesiology and Intensive Care, Karolinska Hospital, Stockholm, Sweden
    J Clin Invest 113:106-14. 2004
  6. ncbi request reprint Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate
    Emmelie A Jansson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm 171 77, Sweden
    Free Radic Biol Med 42:510-8. 2007
  7. ncbi request reprint A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
    Emmelie A Jansson
    Department of Physiology and Pharmacology, Karolinska Institutet, Nanna Svartz vag 2, SE 171 77 Stockholm, Sweden
    Nat Chem Biol 4:411-7. 2008
  8. ncbi request reprint eNOS involved in colitis-induced mucosal blood flow increase
    Joel Petersson
    Dept of Medical Cell Biology, Uppsala Univ, S 751 23 Uppsala, Sweden
    Am J Physiol Gastrointest Liver Physiol 293:G1281-7. 2007
  9. pmc The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
    Malin E V Johansson
    Department of Medical Biochemistry, University of Gothenburg, 405 30 Gothenburg, Sweden
    Proc Natl Acad Sci U S A 105:15064-9. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Dietary nitrate increases gastric mucosal blood flow and mucosal defense
    Joel Petersson
    Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Gastrointest Liver Physiol 292:G718-24. 2007
    ..The gastroprotective effect likely involves a higher mucosal blood flow caused by nonenzymatic NO production. These data suggest an important physiological role of nitrate in the diet...
  2. doi request reprint Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash
    Joel Petersson
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Free Radic Biol Med 46:1068-75. 2009
    ..These results suggest that oral symbiotic bacteria modulate gastrointestinal and cardiovascular function via bioactivation of salivary nitrate. Excessive use of antiseptic mouthwashes may attenuate the bioactivity of dietary nitrate...
  3. pmc iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats
    Olof Schreiber
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    PLoS ONE 8:e71843. 2013
    ..To investigate colonic mucus thickness in vivo in health and during experimental inflammatory bowel disease...
  4. pmc Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction
    Johan Dicksved
    Department of Microbiology, Uppsala BioCenter, Swedish University of Agricultural Sciences, Uppsala, Sweden
    PLoS ONE 7:e46399. 2012
    ..However, L. reuteri decreased the bacterial translocation from the intestine to mesenteric lymph nodes during DSS treatment, which might be an important part of the mechanisms by which L. reuteri ameliorates DSS induced colitis...
  5. pmc Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
    HåKan Björne H
    Department of Anesthesiology and Intensive Care, Karolinska Hospital, Stockholm, Sweden
    J Clin Invest 113:106-14. 2004
    ..These effects are likely mediated through nonenzymatic generation of NO via activation of guanylyl cyclase. This supports a gastroprotective role of salivary nitrate/nitrite...
  6. ncbi request reprint Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate
    Emmelie A Jansson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm 171 77, Sweden
    Free Radic Biol Med 42:510-8. 2007
    ..Future studies will reveal if a diet rich in nitrate can offer an additional nutritional approach to preventing and treating peptic ulcer disease...
  7. ncbi request reprint A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
    Emmelie A Jansson
    Department of Physiology and Pharmacology, Karolinska Institutet, Nanna Svartz vag 2, SE 171 77 Stockholm, Sweden
    Nat Chem Biol 4:411-7. 2008
    ..Our findings suggest a role for mammalian nitrate reduction in regulation of nitrite and NO homeostasis...
  8. ncbi request reprint eNOS involved in colitis-induced mucosal blood flow increase
    Joel Petersson
    Dept of Medical Cell Biology, Uppsala Univ, S 751 23 Uppsala, Sweden
    Am J Physiol Gastrointest Liver Physiol 293:G1281-7. 2007
    ..iNOS and eNOS mRNA increased in both colitis models, whereas nNOS remained at the control level. TNBS- and DSS-induced colitis results in increased colonic mucosal blood flow, most probably due to increased eNOS activity...
  9. pmc The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
    Malin E V Johansson
    Department of Medical Biochemistry, University of Gothenburg, 405 30 Gothenburg, Sweden
    Proc Natl Acad Sci U S A 105:15064-9. 2008
    ..These findings show that the Muc2 mucin can build a mucus barrier that separates bacteria from the colon epithelia and suggest that defects in this mucus can cause colon inflammation...