Pinelopi Lundquist

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi Potential of [11C]DASB for measuring endogenous serotonin with PET: binding studies
    Pinelopi Lundquist
    Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, SE 751 24 Uppsala, Sweden
    Nucl Med Biol 32:129-36. 2005
  2. ncbi 5-Hydroxy-L-[beta-11C]tryptophan versus alpha-[11C]methyl-L-tryptophan for positron emission tomography imaging of serotonin synthesis capacity in the rhesus monkey brain
    Pinelopi Lundquist
    Department of Pharmaceutical Biosciences, Division of Pharmacokinetics and Drug Therapy, Uppsala University, Uppsala, Sweden
    J Cereb Blood Flow Metab 27:821-30. 2007
  3. ncbi Effect on [11C]DASB binding after tranylcypromine-induced increase in serotonin concentration: positron emission tomography studies in monkeys and rats
    Pinelopi Lundquist
    Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, SE 751 24 Uppsala, Sweden
    Synapse 61:440-9. 2007
  4. ncbi Validation studies on the 5-hydroxy-L-[beta-11C]-tryptophan/PET method for probing the decarboxylase step in serotonin synthesis
    Pinelopi Lundquist
    Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-751 24 Uppsala, Sweden
    Synapse 59:521-31. 2006

Detail Information

Publications4

  1. ncbi Potential of [11C]DASB for measuring endogenous serotonin with PET: binding studies
    Pinelopi Lundquist
    Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, SE 751 24 Uppsala, Sweden
    Nucl Med Biol 32:129-36. 2005
    ..Ex vivo experiments performed after tranylcypromine injection (3 or 15 mg/kg) showed a dose-dependent trend in radioactivity uptake and suggested that serotonin may compete with [11C]DASB for transporter binding...
  2. ncbi 5-Hydroxy-L-[beta-11C]tryptophan versus alpha-[11C]methyl-L-tryptophan for positron emission tomography imaging of serotonin synthesis capacity in the rhesus monkey brain
    Pinelopi Lundquist
    Department of Pharmaceutical Biosciences, Division of Pharmacokinetics and Drug Therapy, Uppsala University, Uppsala, Sweden
    J Cereb Blood Flow Metab 27:821-30. 2007
    ..This suggests that the regional net accumulation rates obtained with these two PET tracers will be of different magnitude, which might be related to the activity of each targeted enzyme...
  3. ncbi Effect on [11C]DASB binding after tranylcypromine-induced increase in serotonin concentration: positron emission tomography studies in monkeys and rats
    Pinelopi Lundquist
    Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, SE 751 24 Uppsala, Sweden
    Synapse 61:440-9. 2007
    ..The possibility of using [(11)C]DASB as a tool for monitoring changes in endogenous serotonin concentrations merits further investigation...
  4. ncbi Validation studies on the 5-hydroxy-L-[beta-11C]-tryptophan/PET method for probing the decarboxylase step in serotonin synthesis
    Pinelopi Lundquist
    Division of Pharmacokinetics and Drug Therapy, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-751 24 Uppsala, Sweden
    Synapse 59:521-31. 2006
    ..e., the conversion of HTP to serotonin). Elimination of the radiotracer metabolite [(11)C]HIAA from the brain may be considered negligible if the PET study is limited to 60 min...