Hans Lithell

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial
    Hans Lithell
    Department of Public Health and Caring Sciences, Sections of Geriatrics Clinical Hypertension Research and Family Medicine, University of Uppsala, Uppsala, Sweden
    J Hypertens 21:875-86. 2003
  2. ncbi The Study on COgnition and Prognosis in the Elderly (SCOPE); outcomes in patients not receiving add-on therapy after randomization
    Hans Lithell
    Department of Public Health and Caring Sciences, Section of Geriatrics, University of Uppsala, Sweden
    J Hypertens 22:1605-12. 2004
  3. ncbi Insulin resistance, dietary fat intake and blood pressure predict left ventricular diastolic function 20 years later
    Johan Arnlov
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Nutr Metab Cardiovasc Dis 15:242-9. 2005
  4. ncbi Evaluation of a scoring scheme, including proinsulin and the apolipoprotein B/apolipoprotein A1 ratio, for the risk of acute coronary events in middle-aged men: Uppsala Longitudinal Study of Adult Men (ULSAM)
    Kristina Dunder
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Am Heart J 148:596-601. 2004
  5. ncbi The majority of nondipping men do not have increased cardiovascular risk: a population-based study
    Kristina Björklund
    Department of Public Health and Caring Sciences Section of Geriatrics, University of Uppsala, Uppsala, Sweden
    J Hypertens 20:1501-6. 2002
  6. ncbi Prognostic significance of 24-h ambulatory blood pressure characteristics for cardiovascular morbidity in a population of elderly men
    Kristina Björklund
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    J Hypertens 22:1691-7. 2004
  7. ncbi Cardiovascular risk factors for stable angina pectoris versus unheralded myocardial infarction
    Kristina Dunder
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Am Heart J 147:502-8. 2004
  8. ncbi A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men
    Johan Arnlov
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Am Heart J 149:902-7. 2005
  9. ncbi Isolated ambulatory hypertension predicts cardiovascular morbidity in elderly men
    Kristina Björklund
    Department of Public Health and Caring Sciences Section of Geriatrics, Uppsala University, Uppsala, Sweden
    Circulation 107:1297-302. 2003
  10. ncbi Smoking and the risk of fracture in older men
    Helena Olofsson
    Section of Orthopedics, Department of Surgical Sciences, University Hospital, Uppsala, Sweden
    J Bone Miner Res 20:1208-15. 2005

Detail Information

Publications34

  1. ncbi The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial
    Hans Lithell
    Department of Public Health and Caring Sciences, Sections of Geriatrics Clinical Hypertension Research and Family Medicine, University of Uppsala, Uppsala, Sweden
    J Hypertens 21:875-86. 2003
    ..The prognostic benefits of blood pressure lowering treatment in elderly hypertensive patients were established more than a decade ago, but are less clear in those with mildly to moderately elevated blood pressure...
  2. ncbi The Study on COgnition and Prognosis in the Elderly (SCOPE); outcomes in patients not receiving add-on therapy after randomization
    Hans Lithell
    Department of Public Health and Caring Sciences, Section of Geriatrics, University of Uppsala, Sweden
    J Hypertens 22:1605-12. 2004
    ..e. in patients that best reflect the original intention of a placebo-controlled trial...
  3. ncbi Insulin resistance, dietary fat intake and blood pressure predict left ventricular diastolic function 20 years later
    Johan Arnlov
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Nutr Metab Cardiovasc Dis 15:242-9. 2005
    ....
  4. ncbi Evaluation of a scoring scheme, including proinsulin and the apolipoprotein B/apolipoprotein A1 ratio, for the risk of acute coronary events in middle-aged men: Uppsala Longitudinal Study of Adult Men (ULSAM)
    Kristina Dunder
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Am Heart J 148:596-601. 2004
    ....
  5. ncbi The majority of nondipping men do not have increased cardiovascular risk: a population-based study
    Kristina Björklund
    Department of Public Health and Caring Sciences Section of Geriatrics, University of Uppsala, Uppsala, Sweden
    J Hypertens 20:1501-6. 2002
    ..To investigate whether nondipping and diabetes are independently related to metabolic risk profile and prevalence of target organ damage in a population setting...
  6. ncbi Prognostic significance of 24-h ambulatory blood pressure characteristics for cardiovascular morbidity in a population of elderly men
    Kristina Björklund
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    J Hypertens 22:1691-7. 2004
    ..This study aimed to investigate the prognostic significance of 24-h ambulatory systolic (SBP), diastolic (DBP) and pulse pressure (PP), and blood pressure (BP) variability for cardiovascular morbidity in elderly men...
  7. ncbi Cardiovascular risk factors for stable angina pectoris versus unheralded myocardial infarction
    Kristina Dunder
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Am Heart J 147:502-8. 2004
    ..This study compared baseline risk factors between subjects in whom stable angina pectoris developed and subjects in whom unheralded fatal or nonfatal MI developed during the follow-up period...
  8. ncbi A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men
    Johan Arnlov
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Am Heart J 149:902-7. 2005
    ..The novel myocardial performance index (MPI, also denoted as Tei-Doppler index) has been suggested to reflect both left ventricular (LV) systolic and diastolic function...
  9. ncbi Isolated ambulatory hypertension predicts cardiovascular morbidity in elderly men
    Kristina Björklund
    Department of Public Health and Caring Sciences Section of Geriatrics, Uppsala University, Uppsala, Sweden
    Circulation 107:1297-302. 2003
    ..This study aimed to investigate the prognostic significance of isolated ambulatory hypertension for cardiovascular morbidity in a population of elderly men...
  10. ncbi Smoking and the risk of fracture in older men
    Helena Olofsson
    Section of Orthopedics, Department of Surgical Sciences, University Hospital, Uppsala, Sweden
    J Bone Miner Res 20:1208-15. 2005
    ..Using time-dependent exposure information and analysis, smoking was detected to be a stronger, dose-dependent and a more long lasting risk factor for fracture than has previously been estimated...
  11. ncbi hUNC-93B1, a novel gene mainly expressed in the heart, is related to left ventricular diastolic function, heart failure morbidity and mortality in elderly men
    Johan Arnlov
    Department of Public Health and Caring Sciences Geriatrics, PO Box 609, S 75125 Uppsala, Sweden
    Eur J Heart Fail 7:958-65. 2005
    ..The hUNC-93B1 gene has the highest expression in the heart. We aimed to explore relationships between the hUNC-93B1 gene and cardiac function, morbidity and mortality in elderly men...
  12. ncbi Evaluation and application of the General Motor Function assessment scale in geriatric rehabilitation
    Anna Cristina Aberg
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    Disabil Rehabil 25:360-8. 2003
    ..To test General Motor Function assessment scale (GMF) for concurrent validity, to analyse the distribution of scores and its clinical sensitivity in a setting of geriatric rehabilitation...
  13. ncbi Development and reliability of the General Motor Function Assessment Scale (GMF)--a performance-based measure of function-related dependence, pain and insecurity
    Anna Cristina Aberg
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, PO Box 609 S 751 25, Uppsala, Sweden
    Disabil Rehabil 25:462-72. 2003
    ....
  14. ncbi Magnesium infusion improves endothelium-dependent vasodilation in the human forearm
    Arvo Haenni
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Sweden
    Am J Hypertens 15:10-5. 2002
    ..In conclusion, this in vivo study showed that intraarterial magnesium infusion increased EDV in the infused human forearm, which is in accordance with findings in previous in vitro and animal experiments...
  15. pmc Increase in blood glucose concentration during antihypertensive treatment as a predictor of myocardial infarction: population based cohort study
    Kristina Dunder
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, PO Box 609, SE 751 25 Uppsala, Sweden
    BMJ 326:681. 2003
    ..To investigate the impact of an increase in blood glucose on the risk of developing myocardial infarction, with particular emphasis on people taking antihypertensive drugs...
  16. ncbi Skeletal muscle magnesium content is correlated with plasma glucose concentration in patients with essential hypertension treated with lisinopril or bendrofluazide
    Arvo Haenni
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Sweden
    Am J Hypertens 15:735-8. 2002
    ..However, the Mg concentration in skeletal muscle did not significantly predict the insulin sensitivity or glucose tolerance...
  17. ncbi Proinsulin is an independent predictor of coronary heart disease: Report from a 27-year follow-up study
    Bjorn Zethelius
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Sweden
    Circulation 105:2153-8. 2002
    ....
  18. ncbi Serum retinol levels and the risk of fracture
    Karl Michaelsson
    Department of Surgical Sciences, Section of Orthopedics, University Hospital, Uppsala, Sweden
    N Engl J Med 348:287-94. 2003
    ....
  19. ncbi Different metabolic predictors of white-coat and sustained hypertension over a 20-year follow-up period: a population-based study of elderly men
    Kristina Björklund
    Department of Public Health and Caring Sciences Section of Geriatrics, University of Uppsala, Sweden
    Circulation 106:63-8. 2002
    ..The clinical significance of white-coat hypertension is still unclear. Moreover, no study has examined metabolic predictors of white-coat versus sustained hypertension...
  20. ncbi On loss of activity and independence, adaptation improves life satisfaction in old age--a qualitative study of patients' perceptions
    Anna Cristina Aberg
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Sweden
    Qual Life Res 14:1111-25. 2005
    ..Strategies for improving life satisfaction among old people in rehabilitation are suggested...
  21. ncbi Acute elevations of medium- and long-chain fatty acid have different impacts on endothelium-dependent vasodilation in humans
    Peter Steer
    Department of Medical Sciences Internal Medicine, University Hospital, SE 751 85 Uppsala, Sweden
    Lipids 38:15-9. 2003
    ..05). In conclusion, an acute elevation of LCFA attenuated EDV, whereas an elevation of both MCFA and LCFA did not influence EDV. Thus, FA composition seems to be of importance for EDV in healthy humans...
  22. ncbi Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: Study on COgnition and Prognosis in the Elderly (SCOPE)
    Ingmar Skoog
    Institute of Clinical Neurosciences, Neuropsychiatric Epidemiology Unit, Sahlgrenska Academy, Goteborg University, Goteborg, Sweden
    Am J Hypertens 18:1052-9. 2005
    ..We examined whether cognitive function at baseline affected cognitive and cardiovascular outcomes in the Study on COgnition and Prognosis in the Elderly (SCOPE), a blood pressure (BP)-lowering intervention trial...
  23. ncbi Insulin-mediated vasodilatation, but not glucose uptake or endothelium-mediated vasodilatation, is enhanced in young females compared with males
    Lars Lind
    Department of Internal Medicine, University Hospital, S 751 85 Uppsala, Sweden
    Clin Sci (Lond) 102:241-6. 2002
    ..However, no differences between the sexes were seen with regard to insulin-mediated glucose uptake and the ability of insulin to enhance endothelium-dependent vasodilatation...
  24. ncbi Fetal, developmental, and parental influences on childhood systolic blood pressure in 600 sib pairs: the Uppsala Family study
    David A Leon
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Circulation 112:3478-85. 2005
    ..A study of within- and between-family associations of birth weight with blood pressure, which collected data on both parents, would address this gap in our knowledge...
  25. ncbi The Study on COgnition and Prognosis in the Elderly (SCOPE) - major CV events and stroke in subgroups of patients
    Peter Trenkwalder
    Department of Internal Medicine, Starnberg Hospital, Ludwig Maximilian University Munich, Osswaldstrasse 1, D 82319 Starnberg, Germany
    Blood Press 14:31-7. 2005
    ..However, the benefit was particularly pronounced in patients who entered the study with a previous stroke...
  26. ncbi Cognitive function and health-related quality of life in elderly patients with hypertension--baseline data from the study on cognition and prognosis in the elderly (SCOPE)
    Alessio degl'Innocenti
    AstroZeneca R and D, Molndal, Sweden
    Blood Press 11:157-65. 2002
    ..Age and the use of psychotropic drugs, but not gender and education level, influenced this relationship significantly...
  27. ncbi Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE)
    Vasilios Papademetriou
    Hypertension and Cardiovascular Research, Veterans Administration Medical Center, Washington, DC 20422, USA
    J Am Coll Cardiol 44:1175-80. 2004
    ..The aim of this study was to test the hypothesis that the angiotensin II type 1 receptor blocker (ARB) candesartan can reduce the risk of stroke in elderly patients with isolated systolic hypertension (ISH)...
  28. ncbi Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians
    Søren K Rasmussen
    Steno Diabetes Center and Hagedorn Research Institute, Gentofte, Denmark
    Diabetes 51:3561-7. 2002
    ....
  29. ncbi Continuity of the self in later life: perceptions of informal caregivers
    Anna C Aberg
    Uppsala University, Sweden
    Qual Health Res 14:792-815. 2004
    ..This study underscores the value of informal caregiving and that the caregiving interaction should be balanced by reciprocity...
  30. ncbi The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease
    Helena Ledmyr
    King Gustaf V Research Institute, Karolinska Hospital, Stockholm, Sweden
    Circulation 109:2279-84. 2004
    ..We hypothesize that this polymorphism impacts on coronary heart disease (CHD) risk...
  31. ncbi Vitamin C, diclophenac, and L-arginine protect endothelium-dependent vasodilation against elevated circulating fatty acid levels in humans
    Peter Steer
    Department of Medical Sciences Internal Medicine, University Hospital, SE 75185 Uppsala, Sweden
    Atherosclerosis 168:65-72. 2003
    ..Administration of L-arginine, vitamin C or COX inhibition abolished this effect, suggesting that NEFAs might interact with endothelial vasodilatory function through multiple mechanisms...
  32. ncbi Normalized dyslipidaemia after parathyroidectomy in mild primary hyperparathyroidism: population-based study over five years
    Emil Hagström
    Department of Surgery, Uppsala University Hospital and AstraZeneca R and D, Molndal, Sweden
    Clin Endocrinol (Oxf) 56:253-60. 2002
    ..Secondary dyslipidaemia in pHPT has attracted little attention, although morbidity and mortality associated with cardiovascular diseases have been reported to be increased in these patients...
  33. ncbi [Pharmacogenetics--pathway to individualized antihypertensive pharmacotherapy]
    Lisa Kurland
    Medicincentrum, Akademiska sjukhuset, Uppsala
    Lakartidningen 100:600-3. 2003
    ..The article gives a background to the field, with emphasis on antihypertensive therapy, and prospects for the future...
  34. pmc Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study
    Johan Sundstrom
    Department of Medical Sciences, Uppsala University Hospital, SE 751 85 Uppsala, Sweden
    BMJ 332:878-82. 2006
    ..To find out if the presence of the metabolic syndrome increases the risk of subsequent total and cardiovascular mortality, taking into account established risk factors for cardiovascular disease...