Research Topics
Species | Bo LagerqvistSummaryAffiliation: Uppsala University Hospital Country: Sweden Publications
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Detail Information
Publications
Long-term outcomes with drug-eluting stents versus bare-metal stents in SwedenBo Lagerqvist
Uppsala Clinical Research Center, Uppsala University Hospital, Uppsala, Sweden
N Engl J Med 356:1009-19. 2007..Recent reports have indicated that there may be an increased risk of late stent thrombosis with the use of drug-eluting stents, as compared with bare-metal stents...
N-terminal pro-brain natriuretic peptide in relation to inflammation, myocardial necrosis, and the effect of an invasive strategy in unstable coronary artery diseaseTomas Jernberg
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 42:1909-16. 2003....
Pathophysiologic mechanisms of persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndromeKai M Eggers
Department of Medical Sciences, Cardiology, Uppsala University Hospital, Uppsala, Sweden
Am Heart J 156:588-94. 2008..We now have studied the associations of persistently elevated cTnI levels to cardiac performance, inflammation, coagulation, coronary status, and treatment strategy in these patients...
Long-term safety and efficacy of drug-eluting versus bare-metal stents in SwedenStefan K James
Department of Cardiology, Uppsala University Hospital, Uppsala, Sweden
N Engl J Med 360:1933-45. 2009..The long-term safety and efficacy of drug-eluting coronary stents have been questioned...
Prognostic value of biomarkers during and after non-ST-segment elevation acute coronary syndromeKai M Eggers
Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Centre, Uppsala, Sweden
J Am Coll Cardiol 54:357-64. 2009..The aim of this study was to assess risk prediction by different biomarkers in patients with an ongoing non-ST-segment elevation acute coronary syndrome (NSTE-ACS) and after clinical stabilization...
Stent thrombosis in Sweden: a report from the Swedish Coronary Angiography and Angioplasty RegistryBo Lagerqvist
Uppsala Clinical Research Centre, Uppsala University Hospital, Uppsala, Sweden
Circ Cardiovasc Interv 2:401-8. 2009..The objective was to evaluate the role of risk factors and stent type for stent thrombosis (ST) using a large real world registry...
Growth-differentiation factor-15 for long-term risk prediction in patients stabilized after an episode of non-ST-segment-elevation acute coronary syndromeKai M Eggers
Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Center, Uppsala, Sweden
Circ Cardiovasc Genet 3:88-96. 2010..This study assessed the time course and the long-term prognostic relevance of GDF-15 levels measured repetitively in patients with non-ST-segment-elevation acute coronary syndrome during 6 months after the acute event...
Effects of an early invasive strategy on ischemia and exercise tolerance among patients with unstable coronary artery diseaseErik Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Am J Med 115:606-12. 2003..An early invasive approach after an episode of unstable coronary artery disease has beneficial effects on mortality and myocardial infarction, but its effects on exercise capacity and ischemia have not been investigated...
Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkersNina Johnston
The Division of Medical Sciences, Department of Cardiology, University Hospital, Uppsala, Sweden
Am J Cardiol 97:640-5. 2006....
Relationship between clopidogrel-induced platelet P2Y12 inhibition and stent thrombosis or myocardial infarction after percutaneous coronary intervention-a case-control studyChristoph Varenhorst
Uppsala Clinical Research Center, Department of Medical Sciences, Cardiology, Uppsala University, Sweden
Am Heart J 162:363-71. 2011..On-clopidogrel platelet reactivity was investigated in patients with previous angiographically confirmed STh, myocardial infarction (MI), and controls...
Early invasive treatment benefits patients with renal dysfunction in unstable coronary artery diseaseNina Johnston
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
Am Heart J 152:1052-8. 2006..Few studies have investigated the effects of an early revascularization in relation to renal function in patients with unstable coronary artery disease (CAD)...
Eptifibatide is noninferior to abciximab in primary percutaneous coronary intervention: results from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry)Axel Akerblom
Department of Cardiology, UppsalaClinical Research Center, Uppsala University, Uppsala, Sweden
J Am Coll Cardiol 56:470-5. 2010..The aim of this study was to test the noninferiority of eptifibatide relative to abciximab in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI)...
Lower risk of stent thrombosis and restenosis with unrestricted use of 'new-generation' drug-eluting stents: a report from the nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR)Giovanna Sarno
Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden
Eur Heart J 33:606-13. 2012..To compare the long-term outcome after percutaneous coronary intervention with 'new-generation' drug-eluting stents (n-DES) to 'older generation' DES (o-DES), and bare-metal stents (BMS) in a real-world population...
Cardiovascular risk factors for stable angina pectoris versus unheralded myocardial infarctionKristina Dunder
Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
Am Heart J 147:502-8. 2004..This study compared baseline risk factors between subjects in whom stable angina pectoris developed and subjects in whom unheralded fatal or nonfatal MI developed during the follow-up period...
Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytesAnders Malarstig
Division of Clinical Chemistry, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
Arterioscler Thromb Vasc Biol 25:2667-72. 2005..Moreover, we wanted to investigate the impact of associated TF SNPs on mRNA production in human monocytes...
A long-term perspective on the protective effects of an early invasive strategy in unstable coronary artery disease: two-year follow-up of the FRISC-II invasive studyBo Lagerqvist
Department of Cardiology, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 40:1902-14. 2002..We sought to report the first and repeat events and to separate spontaneous and procedure-related events over two years in the Fast Revascularization during InStability in Coronary artery disease (FRISC-II) invasive trial...
The prognostic and therapeutic implications of increased troponin T levels and ST depression in unstable coronary artery disease: the FRISC II invasive troponin T electrocardiogram substudyErik Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Am Heart J 143:760-7. 2002....
Persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome predicts long-term mortalityKai M Eggers
Department of Medical Sciences, Cardiology, University Hospital Uppsala, S 751 85 Uppsala, Sweden
Circulation 116:1907-14. 2007..However, the prevalence and prognostic importance of persistent troponin elevation in stabilized patients after an episode of non-ST-elevation acute coronary syndrome are unknown and were therefore assessed in this study...
Quantitative analysis of the admission electrocardiogram identifies patients with unstable coronary artery disease who benefit the most from early invasive treatmentLene Holmvang
The Heart Center 2141, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
J Am Coll Cardiol 41:905-15. 2003..The present study is a sub-study of the previously published Fast Revascularization during InStability in Coronary artery disease trial (FRISC-II)...
Diabetes mellitus: the major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularizationAnna Norhammar
Department of Cardiology, Karolinska Hospital, Stockholm, Sweden
J Am Coll Cardiol 43:585-91. 2004..This study was designed to study the influence of diabetes on the outcome of unstable coronary artery disease (CAD)...
Consideration of the total ST-segment deviation on the initial electrocardiogram for predicting final acute posterior myocardial infarct size in patients with maximum ST-segment deviation as depression in leads V1 through V3. A FRISC II substudyRasmus S Ripa
Division of Cardiology, Duke University Medical Center, Durham, NC 27705, USA
J Electrocardiol 38:180-6. 2005..The formula derived could be valuable for selecting patients who fail to meet strict ST-elevation AMI criteria for emergency intravenous or intracoronary reperfusion therapy...
Oxidized low-density lipoprotein as a predictor of outcome in patients with unstable coronary artery diseaseNina Johnston
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, 751 85 Uppsala, Sweden
Int J Cardiol 113:167-73. 2006..The prognostic value of circulating oxidized low-density lipoprotein (OxLDL) in patients with unstable coronary artery disease (CAD) is unknown...
5-year outcomes in the FRISC-II randomised trial of an invasive versus a non-invasive strategy in non-ST-elevation acute coronary syndrome: a follow-up studyBo Lagerqvist
Department of Cardiology and Uppsala Clinical Research Center, University Hospital, S-751 85 Uppsala, Sweden
Lancet 368:998-1004. 2006..INTERPRETATION: The 5-year outcome of this trial indicates sustained benefit of an early invasive strategy in patients with non-ST-elevation acute coronary syndrome at moderate to high risk...
Early invasive vs conservative treatment strategies in women and men with unstable angina and non-ST-segment elevation myocardial infarction: a meta-analysisMichelle O'Donoghue
TIMI Study Group, Brigham and Women s Hospital, 350 Longwood Ave, First Floor, Boston, MA 02115, USA
JAMA 300:71-80. 2008..Although an invasive strategy is frequently used in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS), data from some trials suggest that this strategy may not benefit women...
Outcome of percutaneous coronary intervention in hospitals with and without on-site cardiac surgery standbyJorg Carlsson
Department of Internal Medicine, Division of Cardiology, Lanssjukhuset, Kalmar, Sweden
Heart 93:335-8. 2007..To compare characteristics and outcome of patients undergoing percutaneous coronary intervention (PCI) in clinics with (WSB) or without (NOSB) on-site cardiac surgery backup...
