L Kurland

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Single nucleotide polymorphisms in the apolipoprotein B and low density lipoprotein receptor genes affect response to antihypertensive treatment
    Ulrika Liljedahl
    Department of Medical Sciences, Uppsala University, Uppsala University Hospital, Entrance 70, 3rd Floor, 751 85 Uppsala, Sweden
    BMC Cardiovasc Disord 4:16. 2004
  2. pmc Adipocyte-derived leucine aminopeptidase genotype and response to antihypertensive therapy
    Par Hallberg
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    BMC Cardiovasc Disord 3:11. 2003
  3. ncbi request reprint Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial
    Lisa Kurland
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Am J Hypertens 17:8-13. 2004
  4. ncbi request reprint The antihypertensive response to irbesartan treatment from a pharmacogenetic perspective
    L Kurland
    Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden
    Minerva Med 94:251-8. 2003
  5. ncbi request reprint [Pharmacogenetics--pathway to individualized antihypertensive pharmacotherapy]
    Lisa Kurland
    Medicincentrum, Akademiska sjukhuset, Uppsala
    Lakartidningen 100:600-3. 2003
  6. ncbi request reprint Hypertension and SNP genotyping in antihypertensive treatment
    Lisa Kurland
    Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden
    Cardiovasc Toxicol 5:133-42. 2005
  7. ncbi request reprint Using genotyping to predict responses to anti-hypertensive treatment
    Lisa Kurland
    Department of Medical Sciences, Uppsala University Hospital, 751 85 Uppsala, Sweden
    Trends Pharmacol Sci 26:443-7. 2005
  8. doi request reprint The relationship between the plasma concentration of irbesartan and the antihypertensive response is disclosed by an angiotensin II type 1 receptor polymorphism: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs. Atenolol (
    Lisa Kurland
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Am J Hypertens 21:836-9. 2008
  9. ncbi request reprint Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial
    Lisa Kurland
    Department of Internal Medicine, Uppsala University Hospital, Sweden
    Am J Hypertens 15:389-93. 2002
  10. ncbi request reprint Polymorphisms in the angiotensinogen and angiotensin II type 1 receptor gene are related to change in left ventricular mass during antihypertensive treatment: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (
    Lisa Kurland
    Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden
    J Hypertens 20:657-63. 2002

Detail Information

Publications20

  1. pmc Single nucleotide polymorphisms in the apolipoprotein B and low density lipoprotein receptor genes affect response to antihypertensive treatment
    Ulrika Liljedahl
    Department of Medical Sciences, Uppsala University, Uppsala University Hospital, Entrance 70, 3rd Floor, 751 85 Uppsala, Sweden
    BMC Cardiovasc Disord 4:16. 2004
    ..Dyslipidemia has been associated with hypertension. The present study explored if polymorphisms in genes encoding proteins in lipid metabolism could be used as predictors for the individual response to antihypertensive treatment...
  2. pmc Adipocyte-derived leucine aminopeptidase genotype and response to antihypertensive therapy
    Par Hallberg
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    BMC Cardiovasc Disord 3:11. 2003
    ..The enzyme seems to be particularly abundant in the heart. Recently, the Arg528-encoding allele of the ALAP gene was shown to be associated with essential hypertension...
  3. ncbi request reprint Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial
    Lisa Kurland
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Am J Hypertens 17:8-13. 2004
    ..Our aim was to determine whether specific single nucleotide polymorphisms (SNPs) in RAAS genes were related to the blood pressure (BP) lowering effect of antihypertensive treatment...
  4. ncbi request reprint The antihypertensive response to irbesartan treatment from a pharmacogenetic perspective
    L Kurland
    Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden
    Minerva Med 94:251-8. 2003
    ..In addition, results from recent pharmacogenetics studies on the antihypertensive effect of the angiotensin II type 1 receptor antagonist irbesartan are presented...
  5. ncbi request reprint [Pharmacogenetics--pathway to individualized antihypertensive pharmacotherapy]
    Lisa Kurland
    Medicincentrum, Akademiska sjukhuset, Uppsala
    Lakartidningen 100:600-3. 2003
    ..The article gives a background to the field, with emphasis on antihypertensive therapy, and prospects for the future...
  6. ncbi request reprint Hypertension and SNP genotyping in antihypertensive treatment
    Lisa Kurland
    Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden
    Cardiovasc Toxicol 5:133-42. 2005
    ..We also discuss some of the novel results of pharmacodynamic studies in antihypertensive treatment, an area in its infancy...
  7. ncbi request reprint Using genotyping to predict responses to anti-hypertensive treatment
    Lisa Kurland
    Department of Medical Sciences, Uppsala University Hospital, 751 85 Uppsala, Sweden
    Trends Pharmacol Sci 26:443-7. 2005
    ..It is therefore necessary to design prospective pharmacogenetic studies that aim to identify a genetic profile that will predict the response to anti-hypertensive treatment...
  8. doi request reprint The relationship between the plasma concentration of irbesartan and the antihypertensive response is disclosed by an angiotensin II type 1 receptor polymorphism: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs. Atenolol (
    Lisa Kurland
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Am J Hypertens 21:836-9. 2008
    ..The aim of this study was to investigate the effect of the plasma concentration of irbesartan, a specific angiotensin II type 1 receptor (AT1R) antagonist, and the blood pressure response in relation to AT1R gene polymorphisms...
  9. ncbi request reprint Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial
    Lisa Kurland
    Department of Internal Medicine, Uppsala University Hospital, Sweden
    Am J Hypertens 15:389-93. 2002
    ..Our aim was to determine whether the aldosterone synthase (CYP11B2) -344 C/T polymorphism was associated with the blood pressure (BP)-lowering response to antihypertensive treatment...
  10. ncbi request reprint Polymorphisms in the angiotensinogen and angiotensin II type 1 receptor gene are related to change in left ventricular mass during antihypertensive treatment: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (
    Lisa Kurland
    Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden
    J Hypertens 20:657-63. 2002
    ..Our aim was to determine if gene polymorphisms in the renin-angiotensin-aldosterone system (RAAS) were related to the degree of change in left ventricular hypertrophy (LVH) during antihypertensive treatment...
  11. ncbi request reprint Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients
    L Kurland
    Department of Internal Medicine, Uppsala University Hospital, Uppsala, Sweden
    J Hypertens 19:1783-7. 2001
    ..To determine whether polymorphisms in the renin-angiotensin system can predict blood pressure-lowering response to antihypertensive treatment; more specifically, in response to treatment with irbesartan or atenolol...
  12. ncbi request reprint Single nucleotide polymorphisms predict the change in left ventricular mass in response to antihypertensive treatment
    Ulrika Liljedahl
    Department of Medical Sciences, Uppsala University, Sweden
    J Hypertens 22:2321-8. 2004
    ....
  13. ncbi request reprint Beta1-adrenergic receptor gene polymorphisms and response to beta1-adrenergic receptor blockade in patients with essential hypertension
    J Karlsson
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    Clin Cardiol 27:347-50. 2004
    ..Both have been associated with altered receptor activity in vitro, and with hypertension and cardiac failure in vivo...
  14. ncbi request reprint Gender-specific association between preproendothelin-1 genotype and reduction of systolic blood pressure during antihypertensive treatment--results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)
    P Hallberg
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    Clin Cardiol 27:287-90. 2004
    ..No study has yet determined the effect of this polymorphism on the change in blood pressure during antihypertensive treatment...
  15. ncbi request reprint Polymorphisms in the renin-angiotensin system and endothelium-dependent vasodilation in normotensive subjects
    L Kurland
    Department of Medical Sciences, Uppsala University Hospital, Sweden
    Clin Physiol 21:343-9. 2001
    ..This together with the observation that the AC AT1R genotype is associated with a reduction in both EDV and EIDV, supports the hypothesis that endothelial vasodilatory function is influenced by genes in the renin-angiotensinogen system...
  16. ncbi request reprint A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response
    Ulrika Liljedahl
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    Pharmacogenetics 13:7-17. 2003
    ..Our results highlight the potential of microarray-based technology for SNP genotyping in pharmacogenetics...
  17. ncbi request reprint Transforming growth factor beta1 genotype and change in left ventricular mass during antihypertensive treatment--results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)
    Par Hallberg
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    Clin Cardiol 27:169-73. 2004
    ..The TGF-beta1 G + 915C polymorphism is associated with interindividual variation in TGF-beta1 production. No study has yet determined the impact of this polymorphism on the response to antihypertensive treatment...
  18. ncbi request reprint B2 bradykinin receptor (B2BKR) polymorphism and change in left ventricular mass in response to antihypertensive treatment: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial
    Par Hallberg
    Department of Medical Sciences, Clinical Research Department 2, Uppsala University Hospital, 75185 Uppsala, Sweden
    J Hypertens 21:621-4. 2003
    ..We aimed to clarify whether the processes found in exercise-induced LV growth in normotensive people also occur in pathological LV hypertrophy...
  19. ncbi request reprint The CYP2C9 genotype predicts the blood pressure response to irbesartan: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial
    Par Hallberg
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    J Hypertens 20:2089-93. 2002
    ..However, its influence on clinical response to treatment with the AT(1) receptor antagonist, irbesartan, has not been investigated...
  20. doi request reprint The carotid artery plaque size and echogenicity are related to different cardiovascular risk factors in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study
    Jessika Andersson
    Department of Medicine, Uppsala University Hospital, 75185 Uppsala, Sweden
    Lipids 44:397-403. 2009
    ..These results suggest that plaque size and echogenicity are influenced by different risk factors...