Affiliation: Uppsala University
Krishnan A, SchiÃ¶th H. The role of G protein-coupled receptors in the early evolution of neurotransmission and the nervous system. J Exp Biol. 2015;218:562-71 pubmed publisher
Le Duc D, Renaud G, Krishnan A, AlmÃ©n M, Huynen L, Prohaska S, et al
. Kiwi genome provides insights into evolution of a nocturnal lifestyle. Genome Biol. 2015;16:147 pubmed publisher
..The kiwi genome provides a valuable genomic resource for future genome-wide comparative analyses to other extinct and extant diurnal ratites. ..
Krishnan A, Dnyansagar R, AlmÃ©n M, Williams M, Fredriksson R, Manoj N, et al
. The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals. BMC Evol Biol. 2014;14:270 pubmed publisher
..In summary, this study provides a framework to perform future experimental and comparative studies to further verify and understand the roles of GPCRs that predates the divergence of bilaterian and eumetazoan lineages. ..
Eriksson A, Williams M, Voisin S, Hansson I, Krishnan A, Philippot G, et al
. Implication of coronin 7 in body weight regulation in humans, mice and flies. BMC Neurosci. 2015;16:13 pubmed publisher
..We conclude that coronin 7 is involved in the regulation of energy homeostasis and this role stems, to some degree, from the effect on feeding for calories and reward. ..
Krishnan A, Almén M, Fredriksson R, Schioth H. Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire. Gene. 2013;526:122-33 pubmed publisher
Krishnan A, Mustafa A, AlmÃ©n M, Fredriksson R, Williams M, SchiÃ¶th H. Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families. Mol Phylogenet Evol. 2015;91:27-40 pubmed publisher
..Our robust classification/hierarchy is essential to further understand the differential roles of GPCR/G protein mediated intracellular signaling system across various metazoan lineages. ..