Arunkumar Krishnan

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Identification of distant Agouti-like sequences and re-evaluation of the evolutionary history of the Agouti-related peptide (AgRP)
    Åke Västermark
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    PLoS ONE 7:e40982. 2012
  2. doi The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus
    Åke Västermark
    Department of Neuroscience, BMC, Uppsala University, 751 24 Uppsala, Sweden
    Eur J Pharmacol 660:61-9. 2011
  3. pmc Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae
    Åke Västermark
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Box 593, 751 24, Uppsala, Sweden
    BMC Evol Biol 11:123. 2011
  4. doi Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire
    Arunkumar Krishnan
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Box 593, 751 24 Uppsala, Sweden Electronic address
    Gene 526:122-33. 2013
  5. doi Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)
    Ravisankar Valsalan
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC Uppsala, Sweden
    Gen Comp Endocrinol 188:123-32. 2013
  6. pmc The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi
    Arunkumar Krishnan
    Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden
    PLoS ONE 7:e29817. 2012

Collaborators

Detail Information

Publications6

  1. pmc Identification of distant Agouti-like sequences and re-evaluation of the evolutionary history of the Agouti-related peptide (AgRP)
    Åke Västermark
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    PLoS ONE 7:e40982. 2012
    ....
  2. doi The early origin of melanocortin receptors, agouti-related peptide, agouti signalling peptide, and melanocortin receptor-accessory proteins, with emphasis on pufferfishes, elephant shark, lampreys, and amphioxus
    Åke Västermark
    Department of Neuroscience, BMC, Uppsala University, 751 24 Uppsala, Sweden
    Eur J Pharmacol 660:61-9. 2011
    ..rubripes) has both genes. This study shows that the most ancient presence of these melanocortin-related sequences is found in elephant shark and lampreys considering the current available sequence data...
  3. pmc Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae
    Åke Västermark
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Box 593, 751 24, Uppsala, Sweden
    BMC Evol Biol 11:123. 2011
    ..We use a method that combines the strengths of hidden Markov models and maximum likelihood to find relationships between drug/metabolite transporter families, and branches within families...
  4. doi Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire
    Arunkumar Krishnan
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Box 593, 751 24 Uppsala, Sweden Electronic address
    Gene 526:122-33. 2013
    ....
  5. doi Early vertebrate origin of melanocortin 2 receptor accessory proteins (MRAPs)
    Ravisankar Valsalan
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC Uppsala, Sweden
    Gen Comp Endocrinol 188:123-32. 2013
    ..An evolutionary rate shift analysis indicated that these genes were under high purifying selection. Overall, this study provides a comprehensive analysis of the evolution and gene repertoire of MRAP and MRAP2...
  6. pmc The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi
    Arunkumar Krishnan
    Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden
    PLoS ONE 7:e29817. 2012
    ..Overall, this study provides the first evidence of the presence of four of the five main GRAFS families in Fungi and clarifies the early evolutionary history of the GPCR superfamily...