Ann Sofi Johansson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi request reprint Physiochemical characterization of the Alzheimer's disease-related peptides A beta 1-42Arctic and A beta 1-42wt
    Ann Sofi Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Rudbeck Laboratory, Sweden
    FEBS J 273:2618-30. 2006
  2. ncbi request reprint Docosahexaenoic acid stabilizes soluble amyloid-beta protofibrils and sustains amyloid-beta-induced neurotoxicity in vitro
    Ann Sofi Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Rudbeck Laboratory, Sweden
    FEBS J 274:990-1000. 2007
  3. ncbi request reprint Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay
    Charlotte Stenh
    Department of Public Health Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    Ann Neurol 58:147-50. 2005
  4. ncbi request reprint Docosahexaenoic acid stimulates non-amyloidogenic APP processing resulting in reduced Abeta levels in cellular models of Alzheimer's disease
    Charlotte Sahlin
    Department of Public Health and Caring Sciences, Rudbeck Laboratory, Uppsala University, Dag Hammarskjölds väg 20, SE 751 85 Uppsala, Sweden
    Eur J Neurosci 26:882-9. 2007
  5. ncbi request reprint Attenuated amyloid-beta aggregation and neurotoxicity owing to methionine oxidation
    Ann Sofi Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Neuroreport 18:559-63. 2007
  6. ncbi request reprint Sensitive ELISA detection of amyloid-beta protofibrils in biological samples
    Hillevi Englund
    Department of Public Health Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    J Neurochem 103:334-45. 2007
  7. ncbi request reprint The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics
    Pontus Aspenstrom
    Ludwig Institute for Cancer Research, Biomedical Center, Uppsala University, Box 595, S 751 24 Uppsala, Sweden
    Exp Cell Res 312:2180-94. 2006

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Physiochemical characterization of the Alzheimer's disease-related peptides A beta 1-42Arctic and A beta 1-42wt
    Ann Sofi Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Rudbeck Laboratory, Sweden
    FEBS J 273:2618-30. 2006
    ....
  2. ncbi request reprint Docosahexaenoic acid stabilizes soluble amyloid-beta protofibrils and sustains amyloid-beta-induced neurotoxicity in vitro
    Ann Sofi Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Rudbeck Laboratory, Sweden
    FEBS J 274:990-1000. 2007
    ..Consequently, AbetaArctic-induced toxicity could not be sustained using docosahexaenoic acid. These results provide new insights into the toxicity of different Abeta aggregates and how endogenous lipids can affect Abeta aggregation...
  3. ncbi request reprint Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay
    Charlotte Stenh
    Department of Public Health Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    Ann Neurol 58:147-50. 2005
    ..Our findings might be of relevance for many neurodegenerative disorders in which soluble protein aggregates are the main neurotoxic species...
  4. ncbi request reprint Docosahexaenoic acid stimulates non-amyloidogenic APP processing resulting in reduced Abeta levels in cellular models of Alzheimer's disease
    Charlotte Sahlin
    Department of Public Health and Caring Sciences, Rudbeck Laboratory, Uppsala University, Dag Hammarskjölds väg 20, SE 751 85 Uppsala, Sweden
    Eur J Neurosci 26:882-9. 2007
    ..In conclusion, our results suggest that the proposed protective role of DHA in Alzheimer's disease pathogenesis might be mediated by altered APP processing and Abeta production...
  5. ncbi request reprint Attenuated amyloid-beta aggregation and neurotoxicity owing to methionine oxidation
    Ann Sofi Johansson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Neuroreport 18:559-63. 2007
    ..We conclude that oxidation of Met-35 significantly attenuates aggregation of Abeta1-42 and Abeta1-40Arctic, and thereby reduces neurotoxicity...
  6. ncbi request reprint Sensitive ELISA detection of amyloid-beta protofibrils in biological samples
    Hillevi Englund
    Department of Public Health Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
    J Neurochem 103:334-45. 2007
    ..This assay provides a novel tool for investigating the role of Abeta protofibrils in AD and has the potential of becoming an important diagnostic assay...
  7. ncbi request reprint The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics
    Pontus Aspenstrom
    Ludwig Institute for Cancer Research, Biomedical Center, Uppsala University, Box 595, S 751 24 Uppsala, Sweden
    Exp Cell Res 312:2180-94. 2006
    ..Taken together, our data indicate that DAAM1 communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system...