Research Topics
| T JernbergSummaryAffiliation: Uppsala University Country: Sweden Publications
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Publications
Observer variability and optimal criteria of transient ischemia during ST monitoring with continuous 12-lead ECGTomas Jernberg
Department of Cardiology, Cardiothoracic Center, University Hospital, 751 85 Uppsala, Sweden
Ann Noninvasive Electrocardiol 7:181-90. 2002..However, the method lacks documentation on optimal criteria for episodes of transient ischemia and on observer variability...
NT-proBNP in unstable coronary artery disease--experiences from the FAST, GUSTO IV and FRISC II trialsTomas Jernberg
Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, University Hospital, Uppsala 751 85, Sweden
Eur J Heart Fail 6:319-25. 2004..e. unstable angina or non-ST-elevation myocardial infarction. This article focuses on the emerging role of N-terminal pro brain natriuretic peptide (NT-proBNP) and the results from the FAST, GUSTO IV and FRISC II trials...
N-terminal pro-brain natriuretic peptide in relation to inflammation, myocardial necrosis, and the effect of an invasive strategy in unstable coronary artery diseaseTomas Jernberg
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 42:1909-16. 2003....
Natriuretic peptides in unstable coronary artery diseaseTomas Jernberg
Department of Medical Sciences, Cardiology and Uppsala Research Center, Sweden
Eur Heart J 25:1486-93. 2004..Before a routine use of BNP or NT-proBNP in unstable CAD can be recommended, the cost-effectiveness of adding these new markers to the currently routine markers and their impact on selection of treatment needs further evaluation...
Comparison between second and third generation troponin T assay in patients with symptoms suggestive of an acute coronary syndrome but without ST segment elevationTomas Jernberg
Department of Medical Sciences, Cardiology, University Hospital, Uppsala, Sweden
Cardiology 100:29-35. 2003..02 microg/l) and thereby an increased risk of future events. We conclude that the improved precision of the 3rd generation assay does have some clinical implications in terms of improved accuracy of triage and improved prognostic value...
Cystatin C: a novel predictor of outcome in suspected or confirmed non-ST-elevation acute coronary syndromeTomas Jernberg
Department of Medical Sciences, Cardiology, Uppsala Research Center, University Hospital, 751 85 Uppsala, Sweden
Circulation 110:2342-8. 2004..Cystatin C is a new and better marker of renal function than creatinine. The aim was therefore to evaluate the prognostic value of cystatin C in this population...
A combination of troponin T and 12-lead electrocardiography: a valuable tool for early prediction of long-term mortality in patients with chest pain without ST-segment elevationTomas Jernberg
Department of Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
Am Heart J 144:804-10. 2002..However, there are few studies about the combination of these 2 methods as a means of predicting long-term outcome...
N-terminal pro brain natriuretic peptide on admission for early risk stratification of patients with chest pain and no ST-segment elevationTomas Jernberg
Department of Medical Sciences, Cardiology, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 40:437-45. 2002..The study evaluated the prognostic value of single measurement of N-terminal pro brain natriuretic peptide (NT-proBNP) obtained on admission in patients with symptoms suggestive of an acute coronary syndrome and no ST-segment elevation...
Usefulness of plasma N-terminal proatrial natriuretic peptide (proANP) as an early predictor of outcome in unstable angina pectoris or non-ST-elevation acute myocardial infarctionTomas Jernberg
Department of Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
Am J Cardiol 89:64-6. 2002
Comparison of continuous vectorcardiography and continuous 12-lead electrocardiography of patients with unstable coronary artery disease: do they identify the same population?T Jernberg
Department of Cardiology, Cardiothoracic Center, University Hospital, Ostra, Goteborg, Sweden
Coron Artery Dis 12:187-95. 2001..Continuous vectorcardiography (cVCG) and continuous 12-lead electrocardiography (c12ECG) are important tools for assessing patients with unstable coronary artery disease...
Comparison between strategies using creatine kinase-MB(mass), myoglobin, and troponin T in the early detection or exclusion of acute myocardial infarction in patients with chest pain and a nondiagnostic electrocardiogramT Jernberg
Department of Cardiology, Cardiothroacic Center, University Hospital, Uppsala, Sweden
Am J Cardiol 86:1367-71, A5. 2000..We conclude that a combination of creatine kinase-MB and troponin T during the first 6 hours enables early detection or exclusion of acute myocardial infarction in this population...
Admission N-terminal pro-brain natriuretic peptide and its interaction with admission troponin T and ST segment resolution for early risk stratification in ST elevation myocardial infarctionE Bjorklund
Department of Cardiology, University Hospital of Uppsala, Uppsala, Sweden
Heart 92:735-40. 2006....
Continuous multilead ST-monitoring identifies patients with unstable coronary artery disease who benefit from extended antithrombotic treatmentT Jernberg
Department of Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
Eur Heart J 23:1093-101. 2002....
Serial analyses of N-terminal pro-B-type natriuretic peptide in patients with non-ST-segment elevation acute coronary syndromes: a Fragmin and fast Revascularisation during In Stability in Coronary artery disease (FRISC)-II substudyBertil Lindahl
Department of Medical Sciences and Cardiology, Uppsala Clinical Research Center, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 45:533-41. 2005....
ST depression in ECG at entry indicates severe coronary lesions and large benefits of an early invasive treatment strategy in unstable coronary artery disease; the FRISC II ECG substudy. The Fast Revascularisation during InStability in Coronary artery disE Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Eur Heart J 23:41-9. 2002..In these patients an early invasive strategy substantially decreases death/myocardial infarction...
ST-segment monitoring with continuous 12-lead ECG improves early risk stratification in patients with chest pain and ECG nondiagnostic of acute myocardial infarctionT Jernberg
Department of Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 34:1413-9. 1999....
The prognostic and therapeutic implications of increased troponin T levels and ST depression in unstable coronary artery disease: the FRISC II invasive troponin T electrocardiogram substudyErik Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Am Heart J 143:760-7. 2002....
Myocardial infarction with normal coronary arteries is common and associated with normal findings on cardiovascular magnetic resonance imaging: results from the Stockholm Myocardial Infarction with Normal Coronaries studyO Collste
Department of Cardiology, Sodersjukhuset, Stockholm, Sweden
J Intern Med 273:189-96. 2013..Cardiovascular magnetic resonance (CMR) imaging has the potential to clarify the underlying pathology in patients with MINCA. The objective of this study was to investigate the diagnostic value of CMR imaging in this group of patients...
Biochemical indicators of cardiac and renal function in a healthy elderly populationNina Johnston
Department of Medical Sciences, Cardiology, University Hospital, Uppsala, Sweden
Clin Biochem 37:210-6. 2004..To examine the distributions of NT-proBNP and cystatin C and their relation to age, gender, and other physiological factors in an apparently healthy elderly population...
Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkersNina Johnston
The Division of Medical Sciences, Department of Cardiology, University Hospital, Uppsala, Sweden
Am J Cardiol 97:640-5. 2006....
Oxidized low-density lipoprotein as a predictor of outcome in patients with unstable coronary artery diseaseNina Johnston
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, 751 85 Uppsala, Sweden
Int J Cardiol 113:167-73. 2006..The prognostic value of circulating oxidized low-density lipoprotein (OxLDL) in patients with unstable coronary artery disease (CAD) is unknown...
QT dispersion measured by an automatic continuous method early in patients admitted for chest painMilos Kesek
Department of Cardiology, Akademiska Hospital, 751 85 Uppsala, Sweden
Int J Cardiol 85:217-24; discussion 225-7. 2002..A problem with the manual measurement of QTd is operator dependency. This can be avoided by using an automatic method. We investigated QTd, derived from multiple automatic measurements, as a risk marker in a population with chest pain...
The relation of QT dispersion and localized QT difference to coronary pathology in a population with unstable coronary artery diseaseMilos Kesek
Department of Cardiology, Norrland University Hospital, 90185 Umea, Sweden
Ann Noninvasive Electrocardiol 8:22-9. 2003..In order to elucidate a possible local mechanism, we investigated the relation between QT dispersion, an ECG parameter reflecting the local dispersion, and angiographical measures in a population with unstable coronary artery disease...
Effects of an early invasive strategy on ischemia and exercise tolerance among patients with unstable coronary artery diseaseErik Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Am J Med 115:606-12. 2003..An early invasive approach after an episode of unstable coronary artery disease has beneficial effects on mortality and myocardial infarction, but its effects on exercise capacity and ischemia have not been investigated...
Admission Troponin T and measurement of ST-segment resolution at 60 min improve early risk stratification in ST-elevation myocardial infarctionErik Bjorklund
Department of Cardiology, University Hospital of Uppsala, Sweden
Eur Heart J 25:113-20. 2004..However, the combination of these two early available markers for predicting risk has not been evaluated...
Non-dipolar content of the T-wave as a measure of repolarization inhomogeneity in ST-elevation myocardial infarctionMilos Kesek
Department of Cardiology, Heart Centre, University Hospital, Umea, Sweden
Clin Physiol Funct Imaging 26:362-70. 2006..Resolution of the ST-elevation is associated with a decrease. The increased non-dipolar content reflects a property of the repolarization phase, which is related to but separated from the ST-elevation...
Early invasive treatment benefits patients with renal dysfunction in unstable coronary artery diseaseNina Johnston
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
Am Heart J 152:1052-8. 2006..Few studies have investigated the effects of an early revascularization in relation to renal function in patients with unstable coronary artery disease (CAD)...
Ticagrelor versus clopidogrel in patients with acute coronary syndromesLars Wallentin
Uppsala Clinical Research Center, Uppsala, Sweden
N Engl J Med 361:1045-57. 2009..Ticagrelor is an oral, reversible, direct-acting inhibitor of the adenosine diphosphate receptor P2Y12 that has a more rapid onset and more pronounced platelet inhibition than clopidogrel...
Principal component analysis of the T wave in patients with chest pain and conduction disturbancesMilos Kesek
Department of Cardiology, Norrland University Hospital, Umea, Sweden
Pacing Clin Electrophysiol 27:1378-87. 2004..The nondipolar PCA component contained a moderate amount of prognostic information not present in a simple ECG diagnosis of a conduction disturbance...
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery diseaseTomas Jernberg
Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, University Hospital, 751 85 Uppsala, Sweden
Eur Heart J 27:1166-73. 2006..0007). CONCLUSION: In this population, prasugrel (40-60 mg LD and 10-15 mg MD) achieves greater IPA and a lower proportion of pharmacodynamic non-responders compared with the approved clopidogrel dosing...
[BNP or NT-proBNP should be analyzed in suspected heart failure. Guidelines for analysis and interpretation]Tomas Jernberg
, Karolinska Universitetssjukhuset, Stockholm
Lakartidningen 103:1289-92, 1295. 2006
NT-ProBNP in non-ST-elevation acute coronary syndromeTomas Jernberg
Department of Medical Sciences and Cardiology and the Uppsala Clinical Research Center, Sweden
J Card Fail 11:S54-8. 2005..CONCLUSION: Before routine use of NT-proBNP in NSTACS, the extra cost of adding this new marker to the current routine markers and its impact on selection of treatment should be considered...
Prognostic value of ST-segment resolution-when and what to measurePer Johanson
Clinical Experimental Research Laboratory, Sahlgrenska University Hospital Ostra, SE 41685 Goteborg, Sweden
Eur Heart J 24:337-45. 2003..We now set out to compare the prognostic value of previously suggested cut-offs for ST-segment resolution, and determine the times to measure these...
