Elena Jazin

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Inflammation-related genes up-regulated in schizophrenia brains
    Peter Saetre
    Department of Development and Genetics, Uppsala University, Sweden
    BMC Psychiatry 7:46. 2007
  2. pmc Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain
    Julia Lindberg
    Evolutionary Biology Centre, Department of Evolution, Genomics and Systematics, Uppsala University, Norbyvagen 18D, Uppsala, Sweden
    BMC Neurosci 8:34. 2007
  3. doi request reprint Sex differences in molecular neuroscience: from fruit flies to humans
    Elena Jazin
    Department of Genetics and Development, Evolutionary Biology Centre, Uppsala University, SE 75236, Sweden
    Nat Rev Neurosci 11:9-17. 2010
  4. pmc Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome
    Björn Reinius
    Department of Organismal Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    BMC Genomics 13:607. 2012
  5. doi request reprint RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes
    Katarzyna J Radomska
    Department of Evolution and Development, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Hum Mol Genet 22:1373-82. 2013
  6. pmc Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse
    Björn Reinius
    Department of Evolution and Development, EBC, Uppsala University, Sweden
    BMC Genomics 11:614. 2010
  7. ncbi request reprint Human QKI, a new candidate gene for schizophrenia involved in myelination
    Karolina Aberg
    Department of Evolution, Genomics and Systematics, Uppsala University, Norbyvagen 18D, 752 36 Uppsala, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:84-90. 2006
  8. ncbi request reprint Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels
    Anja Castensson
    Department of Evolution, Genomics and Systematics, Evolutionary Biology Centre EBC, Uppsala University, Uppsala, Sweden
    Am J Med Genet B Neuropsychiatr Genet 134:84-9. 2005
  9. doi request reprint Support for schizophrenia susceptibility locus on chromosome 2q detected in a Swedish isolate using a dense map of microsatellites and SNPs
    Karolina Aberg
    Department of Evolution, Genomics and Systematics, Uppsala University, Uppsala, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:1238-44. 2008
  10. pmc Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia
    Karolina Aberg
    Department of Evolution, Genomics and Systematics, Uppsala University, SE 75236 Uppsala, Sweden
    Proc Natl Acad Sci U S A 103:7482-7. 2006

Detail Information

Publications14

  1. pmc Inflammation-related genes up-regulated in schizophrenia brains
    Peter Saetre
    Department of Development and Genetics, Uppsala University, Sweden
    BMC Psychiatry 7:46. 2007
    ..However, disentangling disease effects from alterations caused by medication is a challenging task. The main goal of this study is to find transcriptional alterations in schizophrenia that are independent of neuroleptic treatment...
  2. pmc Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain
    Julia Lindberg
    Evolutionary Biology Centre, Department of Evolution, Genomics and Systematics, Uppsala University, Norbyvagen 18D, Uppsala, Sweden
    BMC Neurosci 8:34. 2007
    ..However, little is known about molecular alterations downstream of the hypocretin signals...
  3. doi request reprint Sex differences in molecular neuroscience: from fruit flies to humans
    Elena Jazin
    Department of Genetics and Development, Evolutionary Biology Centre, Uppsala University, SE 75236, Sweden
    Nat Rev Neurosci 11:9-17. 2010
    ..The overriding conclusion is that, as for neuroscience in general, molecular neuroscience has to take into account potential sex influences that might modify signalling pathways...
  4. pmc Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome
    Björn Reinius
    Department of Organismal Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    BMC Genomics 13:607. 2012
    ..We performed a large-scale sex-bias expression analysis of genes on the X-chromosome in six different somatic tissues from mouse...
  5. doi request reprint RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes
    Katarzyna J Radomska
    Department of Evolution and Development, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Hum Mol Genet 22:1373-82. 2013
    ..Our findings for QKI, together with its well-known role in myelination, suggest that QKI is a hub regulator of glia function in humans...
  6. pmc Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse
    Björn Reinius
    Department of Evolution and Development, EBC, Uppsala University, Sweden
    BMC Genomics 11:614. 2010
    ....
  7. ncbi request reprint Human QKI, a new candidate gene for schizophrenia involved in myelination
    Karolina Aberg
    Department of Evolution, Genomics and Systematics, Uppsala University, Norbyvagen 18D, 752 36 Uppsala, Sweden
    Am J Med Genet B Neuropsychiatr Genet 141:84-90. 2006
    ..Taken together, we propose QKI as a possible target for functional studies related to the role of myelination in schizophrenia...
  8. ncbi request reprint Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels
    Anja Castensson
    Department of Evolution, Genomics and Systematics, Evolutionary Biology Centre EBC, Uppsala University, Uppsala, Sweden
    Am J Med Genet B Neuropsychiatr Genet 134:84-9. 2005
    ..The disease related changes in HTR2C expression are not related to the promoter variants typed in our sample, but could be due to other regulatory variants or trans-acting factors...
  9. doi request reprint Support for schizophrenia susceptibility locus on chromosome 2q detected in a Swedish isolate using a dense map of microsatellites and SNPs
    Karolina Aberg
    Department of Evolution, Genomics and Systematics, Uppsala University, Uppsala, Sweden
    Am J Med Genet B Neuropsychiatr Genet 147:1238-44. 2008
    ..Haplotype sharing in families helped to delimit the detected regions that potentially are susceptibility loci for schizophrenia...
  10. pmc Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia
    Karolina Aberg
    Department of Evolution, Genomics and Systematics, Uppsala University, SE 75236 Uppsala, Sweden
    Proc Natl Acad Sci U S A 103:7482-7. 2006
    ..Moreover, we hypothesize that previously observed decreased activity of myelin-related genes in schizophrenia might be caused by disturbed QKI splicing...
  11. ncbi request reprint From wild wolf to domestic dog: gene expression changes in the brain
    Peter Saetre
    Department of Evolution, Genomics and Systematics, Uppsala University, Norbyvagen 18D, S 752 36 Uppsala, Sweden
    Brain Res Mol Brain Res 126:198-206. 2004
    ..Instead, they may provide a common mechanism for rapid adaptive changes during speciation, particularly in cases that present strong selective pressures on behavioral characters...
  12. pmc Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells
    Lin Jiang
    Department of Development and Genetics, Uppsala University, Sweden
    BMC Pharmacol 9:6. 2009
    ..Messenger RNA expression levels of splice variants QKI-5, QKI-6 and QKI-7 were measured by Real-Time PCR...
  13. pmc An evolutionarily conserved sexual signature in the primate brain
    Björn Reinius
    Department of Development and Genetics, Uppsala University, Uppsala, Sweden
    PLoS Genet 4:e1000100. 2008
    ..Genes within sexual expression profiles may underlie important functional differences between the sexes, with possible importance during primate evolution...
  14. ncbi request reprint Decrease of serotonin receptor 2C in schizophrenia brains identified by high-resolution mRNA expression analysis
    Anja Castensson
    Department of Evolutionary Biology, Uppsala University, Uppsala, Sweden
    Biol Psychiatry 54:1212-21. 2003
    ..We measured messenger RNA expression levels of 16 candidate genes in brain samples from 55 schizophrenia patients and 55 controls. This is the largest sample so far used to identify genes differentially expressed in schizophrenia brains...