C Janson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Can spirometric norms be set using pre- or post- bronchodilator test results in older people?
    Bernet Kato
    Respiratory Epidemiology and Public Health, National Heart and Lung Institute, Imperial College, London, UK
    Respir Res 13:102. 2012
  2. pmc Association of biomarkers of inflammation and cell adhesion with lung function in the elderly: a population-based study
    Antje Kuhlmann
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala University Hospital, 751 85, Uppsala, Sweden
    BMC Geriatr 13:82. 2013
  3. pmc Pneumonia and pneumonia related mortality in patients with COPD treated with fixed combinations of inhaled corticosteroid and long acting β2 agonist: observational matched cohort study (PATHOS)
    Christer Janson
    Department of Medical Sciences, Respiratory Medicine, Uppsala University, Uppsala, Sweden
    BMJ 346:f3306. 2013
  4. pmc Transient receptor potential genes, smoking, occupational exposures and cough in adults
    Lidwien A M Smit
    INSERM, CESP Centre for research in Epidemiology and Population Health, U1018, Respiratory and environmental epidemiology Team, Villejuif F 94807, France
    Respir Res 13:26. 2012
  5. pmc Early life environment and snoring in adulthood
    Karl A Franklin
    Department of Respiratory Medicine and Allergology, University Hospital, Umea, Sweden
    Respir Res 9:63. 2008
  6. pmc Performance of a new hand-held device for exhaled nitric oxide measurement in adults and children
    K Alving
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 17177 Stockholm, Sweden
    Respir Res 7:67. 2006
  7. pmc Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics
    Kawa Amin
    Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden
    Respir Res 6:110. 2005
  8. pmc Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity
    Gunnar Gudmundsson
    Department of Respiratory Medicine, Allergy and Sleep, Landspitali University Hospital, Reykjavik, Iceland
    Respir Res 7:109. 2006
  9. pmc IgE sensitisation in relation to flow-independent nitric oxide exchange parameters
    Andrei Malinovschi
    Department of Medical Cell Biology Integrative Physiology, Uppsala University, Uppsala, Sweden
    Respir Res 7:92. 2006
  10. pmc Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge
    Mary Kämpe
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Clin Mol Allergy 9:3. 2011

Detail Information

Publications115 found, 100 shown here

  1. pmc Can spirometric norms be set using pre- or post- bronchodilator test results in older people?
    Bernet Kato
    Respiratory Epidemiology and Public Health, National Heart and Lung Institute, Imperial College, London, UK
    Respir Res 13:102. 2012
    ..Chronic Obstructive Pulmonary Disease (COPD) is defined by post-bronchodilator spirometry. Data on "normal values" come predominantly from pre-bronchodilator spirometry. The effects of this on diagnosis are unknown...
  2. pmc Association of biomarkers of inflammation and cell adhesion with lung function in the elderly: a population-based study
    Antje Kuhlmann
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala University Hospital, 751 85, Uppsala, Sweden
    BMC Geriatr 13:82. 2013
    ..The aim of the study was to analyse associations of biomarkers and combinations of biomarkers with lung function in an elderly general population...
  3. pmc Pneumonia and pneumonia related mortality in patients with COPD treated with fixed combinations of inhaled corticosteroid and long acting β2 agonist: observational matched cohort study (PATHOS)
    Christer Janson
    Department of Medical Sciences, Respiratory Medicine, Uppsala University, Uppsala, Sweden
    BMJ 346:f3306. 2013
    ..To investigate the occurrence of pneumonia and pneumonia related events in patients with chronic obstructive pulmonary disease (COPD) treated with two different fixed combinations of inhaled corticosteroid/long acting β2 agonist...
  4. pmc Transient receptor potential genes, smoking, occupational exposures and cough in adults
    Lidwien A M Smit
    INSERM, CESP Centre for research in Epidemiology and Population Health, U1018, Respiratory and environmental epidemiology Team, Villejuif F 94807, France
    Respir Res 13:26. 2012
    ..The aim was to study the influence of single nucleotide polymorphisms (SNPs) in TRP genes and irritant exposures on cough...
  5. pmc Early life environment and snoring in adulthood
    Karl A Franklin
    Department of Respiratory Medicine and Allergology, University Hospital, Umea, Sweden
    Respir Res 9:63. 2008
    ..To our knowledge, no studies of the possible association of early life environment with snoring in adulthood have been published. We aimed to investigate whether early life environment is associated with snoring later in life...
  6. pmc Performance of a new hand-held device for exhaled nitric oxide measurement in adults and children
    K Alving
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 17177 Stockholm, Sweden
    Respir Res 7:67. 2006
    ..In this study, the performance of a new electrochemical hand-held device for exhaled NO measurements (NIOX MINO) was compared with a standard stationary chemiluminescence unit (NIOX)...
  7. pmc Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics
    Kawa Amin
    Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden
    Respir Res 6:110. 2005
    ..The aim was to characterize the presence of Laminin chains in the SEBM and epithelium in allergic and non-allergic asthmatics...
  8. pmc Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity
    Gunnar Gudmundsson
    Department of Respiratory Medicine, Allergy and Sleep, Landspitali University Hospital, Reykjavik, Iceland
    Respir Res 7:109. 2006
    ....
  9. pmc IgE sensitisation in relation to flow-independent nitric oxide exchange parameters
    Andrei Malinovschi
    Department of Medical Cell Biology Integrative Physiology, Uppsala University, Uppsala, Sweden
    Respir Res 7:92. 2006
    ....
  10. pmc Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge
    Mary Kämpe
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Clin Mol Allergy 9:3. 2011
    ..abstract:..
  11. pmc Systemic and local eosinophil inflammation during the birch pollen season in allergic patients with predominant rhinitis or asthma
    Mary Kämpe
    Department of Medical Sciences, Respiratory Medicine and Allergology University Hospital, Uppsala, Sweden
    Clin Mol Allergy 5:4. 2007
    ..The aim of the study was to investigate inflammation during the birch pollen season in patients with rhinitis or asthma...
  12. pmc Impact of patient characteristics, education and knowledge on emergency room visits in patients with asthma and COPD: a descriptive and correlative study
    Margareta Emtner
    Department of Neuroscience, Physiotherapy, Uppsala University, SE 751 85 Uppsala, Sweden
    BMC Pulm Med 9:43. 2009
    ....
  13. pmc Associations of ECP (eosinophil cationic protein)-gene polymorphisms to allergy, asthma, smoke habits and lung function in two Estonian and Swedish sub cohorts of the ECRHS II study
    Ulla Britt Jönsson
    Department of Medical Sciences, Clinical Chemistry, University of Uppsala, Uppsala, Sweden
    BMC Pulm Med 10:36. 2010
    ..The aim was to study the relationship of these ECP gene polymorphisms to signs and symptoms of allergy and asthma in a community based cohort (The European Community Respiratory Health Survey (ECRHS))...
  14. pmc Persistent Chlamydia Pneumoniae serology is related to decline in lung function in women but not in men. Effect of persistent Chlamydia pneumoniae infection on lung function
    Thorarinn Gislason
    University of Iceland, Faculty of Medicine, Reykjavik, Iceland
    BMC Pulm Med 10:44. 2010
    ..Aim: To estimate the long term respiratory effects of C pn with change in forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) as a main outcome variable...
  15. ncbi request reprint The effect of passive smoking on respiratory health in children and adults
    C Janson
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Int J Tuberc Lung Dis 8:510-6. 2004
    ..Passive smoking is a widespread, important and avoidable risk factor for respiratory symptoms in both children and adults. Reducing passive smoking in the community will have a large positive effect on respiratory health...
  16. ncbi request reprint An Internet survey of asthma treatment
    Christer Janson
    Department of Medical Sciences, Respiratory Medicine, and Allergology, Uppsala University, Uppsala, Sweden
    J Asthma 41:49-55. 2004
    ..We find that many asthmatics have a low level of asthma control, and the survey indicates that underuse of inhaled steroids is one of the reasons why the goals set up in asthma guidelines so far have not been reached...
  17. pmc Insomnia is more common among subjects living in damp buildings
    C Janson
    Department of Medical sciences Respiratory Medicine and Allergology, Akademiska sjukhuset, SE 751 85 Uppsala, Sweden
    Occup Environ Med 62:113-8. 2005
    ..Insomnia is a condition with a high prevalence and a great impact on quality of life. Little is known about the relation between and sleep disturbances and the home environment...
  18. doi request reprint Phenotypes of obstructive lung disease
    C Janson
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden
    Clin Respir J 2:88-91. 2008
    ..Better phenotyping in asthma will hopefully enable us to make progress in this area. Phenotyping is also important for assessment of prognosis in both asthma and COPD...
  19. doi request reprint The importance of airway remodelling in the natural course of asthma
    Christer Janson
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden
    Clin Respir J 4:28-34. 2010
    ..Asthma is associated with airflow limitation and increased decline in lung function. The underlying mechanism for this was probably that persisting inflammation leads to remodelling of the airways...
  20. ncbi request reprint Circulating adhesion molecules in allergic and non-allergic asthma
    Christer Janson
    Department of Medical Sciences, Respiratory Medicine and Allergology, Akademiska sjukhuset, Uppsala University, Uppsala SE 75185, Sweden
    Respir Med 99:45-51. 2005
    ..sVCAM-1 was reduced by inhaled steroids (P<0.01). Our results indicate that endothelial cells are activated in asthma and that this activity has a bearing on airflow variability and bronchial responsiveness in NA...
  21. doi request reprint Risk factors associated with allergic and non-allergic asthma in adolescents
    Christer Janson
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Clin Respir J 1:16-22. 2007
    ..The aim of this investigation was to investigate risk factors associated with allergic and non-allergic asthma in adolescents...
  22. ncbi request reprint Changes in active and passive smoking in the European Community Respiratory Health Survey
    C Janson
    Dept of Medical Sciences, Respiratory Medicine and Allergology, Akademiska sjukhuset, SE 751 85 University of Uppsala, Sweden, and Department of Thoracic Medicine, Haukeland Hospital, Bergen, Norway
    Eur Respir J 27:517-24. 2006
    ..Exposure to other peoples smoking decreased quitting rates and increased the risk of starting to smoke...
  23. ncbi request reprint Changes in the use of anti-asthmatic medication in an international cohort
    C Janson
    Dept of Medical Sciences, Respiratory Medicine and Allergology, Akademiska sjukhuset, SE 751 85 Uppsala, Sweden
    Eur Respir J 26:1047-55. 2005
    ..However, despite increased use of inhaled corticosteroids, a large majority of subjects with symptomatic asthma do not use this treatment on a daily basis, particularly males and smokers with asthma...
  24. ncbi request reprint Effect of passive smoking on respiratory symptoms, bronchial responsiveness, lung function, and total serum IgE in the European Community Respiratory Health Survey: a cross-sectional study
    C Janson
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden
    Lancet 358:2103-9. 2001
    ..This analysis aimed to estimate the effect of passive smoking on respiratory symptoms, bronchial responsiveness, lung function, and total serum IgE in the European Community Respiratory Health Survey...
  25. ncbi request reprint Exhaled nitric oxide levels in school children in relation to IgE sensitisation and window pane condensation
    Christer Janson
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, 751 85 Uppsala, Sweden
    Respir Med 99:1015-21. 2005
    ..A positive relation between exhaled nitric oxide (NO) levels and allergen exposure has been found in some studies whereas there is less information on how non-allergen environmental factors influences exhaled NO...
  26. ncbi request reprint Insomnia in men-a 10-year prospective population based study
    C Janson
    Department of Medical Sciences, Akademiska sjukhuset, Uppsala University, Sweden
    Sleep 24:425-30. 2001
    ..to prospectively analyze changes in the prevalence of insomnia and the relationship between insomnia, aging, lifestyle, and medical disorders..
  27. ncbi request reprint Inflammatory markers in acute exacerbations of obstructive pulmonary disease: predictive value in relation to smoking history
    I Dahlén
    Department of Medical Sciences, Uppsala University, Sweden
    Respir Med 93:744-51. 1999
    ..No correlation was found between neutrophil markers and changes in lung function. We conclude that patients with obstructive pulmonary disease with acute exacerbations and high levels of eosinophil markers respond well to treatment...
  28. ncbi request reprint Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms
    M I Gunnbjörnsdóttir
    Dept of Medical Sciences Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Eur Respir J 24:116-21. 2004
    ..This study adds evidence to an independent relationship between obesity, nocturnal gastro-oesophageal reflux and habitual snoring and the onset of asthma and respiratory symptoms in adults...
  29. pmc Prevalence and incidence of respiratory symptoms in relation to indoor dampness: the RHINE study
    M I Gunnbjörnsdóttir
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Thorax 61:221-5. 2006
    ..An association between indoor dampness and respiratory symptoms has been reported, but dampness as a risk factor for the onset or remission of respiratory symptoms and asthma is not well documented...
  30. ncbi request reprint Inflammation and structural changes in the airways of patients with primary Sjögren's syndrome
    K Amin
    Department of Medical Sciences, Asthma Research Centre, University of Uppsala, Sweden
    Respir Med 95:904-10. 2001
    ..The structural findings, but not the pattern of inflammatory cells, are shared with atopic asthma and may relate to the increased bronchial hyper-responsiveness seen in both diseases...
  31. doi request reprint Asthma symptoms and nasal congestion as independent risk factors for insomnia in a general population: results from the GA(2)LEN survey
    F Sundbom
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Allergy 68:213-9. 2013
    ..The aim of this study was to further analyse the association between asthma, nasal symptoms and insomnia and to identify risk factors for sleep disturbance among patients with asthma, in a large population-based set of material...
  32. ncbi request reprint The European Community Respiratory Health Survey: what are the main results so far? European Community Respiratory Health Survey II
    C Janson
    Dept of Medical Science Respiratory Medicine and Allergology, Uppsala University, Sweden
    Eur Respir J 18:598-611. 2001
    ....
  33. ncbi request reprint Determinants of cough in young adults participating in the European Community Respiratory Health Survey
    C Janson
    Dept of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Sweden
    Eur Respir J 18:647-54. 2001
    ..Females are more likely to report nocturnal and nonproductive cough than males. Cough was related to treatable disorders, like asthma and rhinitis, as well as avoidable factors, such as tobacco smoking and environmental tobacco smoke...
  34. doi request reprint What can we learn about asthma and allergy from the follow-up of the RHINE and the ECRHS studies?
    E Omenaas
    Respiratory Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Clin Respir J 2:45-52. 2008
    ..The aim of the present review is to focus on longitudinal results with regard incidence and net change of asthma and asthma-like symptoms, risk factors and management of asthma, with special reference to the Nordic-Baltic countries...
  35. ncbi request reprint Serum eosinophil cationic protein (S-ECP) in a population with low prevalence of atopy
    R Jogi
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden
    Respir Med 96:525-9. 2002
    ..Our results indicate that the level of eosinophil activation is low in a population with a low prevalence of atopy, even when BHR is common...
  36. ncbi request reprint The association between birth size and atopy in young North-European adults
    B N Laerum
    Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway
    Clin Exp Allergy 35:1022-7. 2005
    ..There is evidence that atopic disorders may begin in intra-uterine life; however, studies of birth characteristics and atopy show conflicting results...
  37. doi request reprint Both allergic and nonallergic asthma are associated with increased FE(NO) levels, but only in never-smokers
    A Malinovschi
    Department of Medical Cell Biology Integrative Physiology, Uppsala University, Uppsala, Sweden
    Allergy 64:55-61. 2009
    ..The aim of this study is to analyze the effect of having allergic or nonallergic asthma on exhaled nitric oxide levels, with special regard to smoking history...
  38. ncbi request reprint Prevalence of sleep disturbances among young adults in three European countries
    C Janson
    Department of Lung Medicine, Akademiska sjukhuset, Uppsala, Sweden
    Sleep 18:589-97. 1995
    ..The significant correlation between reported GER and subjective quality of sleep should be followed up in studies using objective measurements...
  39. doi request reprint Onset of mucosal, dermal, and general symptoms in relation to biomarkers and exposures in the dwelling: a cohort study from 1992 to 2002
    B Sahlberg
    Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University Hospital and Uppsala University, Uppsala, Sweden
    Indoor Air 22:331-8. 2012
    ..97). In conclusion, female gender, dampness or indoor molds, indoor painting, and biomarkers of allergy and inflammation were associated with a higher incidence of SBS symptoms, in particular mucosal symptoms...
  40. ncbi request reprint Role of snoring and daytime sleepiness in occupational accidents
    E Lindberg
    Department of Medical Sciences, Respiratory Medicine and Allergology, Akademiska sjukhuset, Uppsala, Sweden
    Am J Respir Crit Care Med 164:2031-5. 2001
    ..We conclude that sleepy, male snorers have an increased risk of occupational accidents. The results indicate that early identification and treatment of sleep-disordered breathing may reduce the number of injuries at work...
  41. ncbi request reprint Relationship of fish and cod oil intake with adult asthma
    B N Laerum
    Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway
    Clin Exp Allergy 37:1616-23. 2007
    ..However, previous studies show conflicting results and no studies have assessed the potential long-term effects of childhood fish intake on adult asthma...
  42. ncbi request reprint Sleep-disordered breathing and glucose metabolism in hypertensive men: a population-based study
    A Elmasry
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden
    J Intern Med 249:153-61. 2001
    ..Sleep breathing disorders, independent of central obesity, may influence plasma insulin and glycaemia...
  43. ncbi request reprint Changes in inflammatory markers following treatment of acute exacerbations of obstructive pulmonary disease
    I Dahlén
    Deptartment of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University Hospital, Sweden
    Respir Med 95:891-7. 2001
    ..This study indicates that following eosinophil markers is more useful in patients with asthma than patients with COPD...
  44. ncbi request reprint Eczema, atopy and allergen exposure in adults: a population-based study
    J Harrop
    School of Medicine, King s College London, London UK, and Department of Allergy, Respiratory Medicine and Sleep, University Hospital E7, Reykjavik, Iceland
    Clin Exp Allergy 37:526-35. 2007
    ..There are few published studies on geographical variation in prevalence of eczema in adults or its association with recognised risk factors for allergic disease...
  45. ncbi request reprint The relationship between indicators of building dampness and respiratory health in young Swedish adults
    M I Gunnbjörnsdóttir
    Department of Medical Sciences, Respiratory Medicine and Allergology, Akademiska University Hospital, Uppsala, Sweden
    Respir Med 97:302-7. 2003
    ..3-5.6)) compared to subjects reporting no water damage or molds. Long-term cough was also more common in this group (OR 2.2 (95% CI 1.2-4.0)). This study adds evidence to a relationship between damp buildings and respiratory symptoms...
  46. ncbi request reprint Sleep disturbances in a young adult population: can gender differences be explained by differences in psychological status?
    E Lindberg
    Department of Lung Medicine, Uppsala University, Akademiska sjukhuset, Sweden
    Sleep 20:381-7. 1997
    ..The higher prevalence of anxiety among females alone cannot explain the gender differences in sleep disturbances seen in this population...
  47. ncbi request reprint Exhaled nitric oxide in a population-based study of asthma and allergy in schoolchildren
    S L Nordvall
    Department of Women s and Children s Health, Uppsala University, Uppsala, Sweden
    Allergy 60:469-75. 2005
    ..As most asthma cases in a population are mild, the findings suggest that exhaled NO is a sensitive marker of asthma and allergy...
  48. doi request reprint Increased exhaled nitric oxide predicts new-onset rhinitis and persistent rhinitis in adolescents without allergic symptoms
    A Malinovschi
    Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden
    Clin Exp Allergy 42:433-40. 2012
    ..We have previously suggested that elevated FE(NO) levels in the absence of asthma symptoms may be a sign of 'early asthma'. In the present study, we hypothesize that elevated exhaled NO levels may also precede rhinitis symptoms...
  49. ncbi request reprint Increased adhesion to vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 of eosinophils from patients with asthma
    L Hakansson
    Department of Clinical Chemistry, University Hospital, Uppsala, Sweden
    J Allergy Clin Immunol 96:941-50. 1995
    ....
  50. ncbi request reprint Current asthma and biochemical signs of inflammation in relation to building dampness in dwellings
    D Norback
    Department of Occupational and Environmental Medicine, Uppsala University, Sweden
    Int J Tuberc Lung Dis 3:368-76. 1999
    ..Study of current asthma in adults in relation to the indoor environment...
  51. ncbi request reprint Obstructive sleep apnoea and urine catecholamines in hypertensive males: a population-based study
    A Elmasry
    Dept of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Sweden
    Eur Respir J 19:511-7. 2002
    ..Elevated sympathoadrenal activity may explain the increased cardiovascular morbidity associated with obstructive sleep apnoea...
  52. ncbi request reprint The extracellular deposition of mast cell products is increased in hypertrophic airways smooth muscles in allergic asthma but not in nonallergic asthma
    K Amin
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    Allergy 60:1241-7. 2005
    ..The aim of this investigation was to study the distribution of mast cells in different compartments in the bronchial mucosa of allergic and nonallergic asthma in relation to airways remodeling...
  53. ncbi request reprint Symptoms related to the sick building syndrome in a general population sample: associations with atopy, bronchial hyper-responsiveness and anxiety
    E Bjornsson
    Department of Lung Medicine and Asthma Research Centre, Uppsala University, Akademiska sjukhuset, Sweden
    Int J Tuberc Lung Dis 2:1023-8. 1998
    ..The aim of this study was to investigate the characteristics of subjects from the general population that report SBS-related symptoms...
  54. pmc Prevalence of sleep apnoea and snoring in hypertensive men: a population based study
    C Sjostrom
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Sweden
    Thorax 57:602-7. 2002
    ..If so, we further wanted to investigate whether this effect is age dependent...
  55. ncbi request reprint Dyspnea in relation to symptoms of anxiety and depression: A prospective population study
    Asa Neuman
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, SE 751 85 Uppsala, Sweden
    Respir Med 100:1843-9. 2006
    ..Respiratory symptoms are related to anxiety and depression in several cross-sectional studies but the association has not been explored in longitudinal studies...
  56. ncbi request reprint Lung function changes in relation to menstrual cycle in females with cystic fibrosis
    M Johannesson
    Uppsala CF Center, Department of Paediatrics, Uppsala University Hospital, Sweden
    Respir Med 94:1043-6. 2000
    ..These changes are probably related to changes in progesterone levels during the menstrual cycles. This result warrants further studies to understand the complexity of CF lung disease in women...
  57. doi request reprint Quantitative PCR analysis of fungal DNA in Swedish day care centers and comparison with building characteristics and allergen levels
    G H Cai
    Dept of Medical Science, Occupational and Environmental Medicine, University Hospital, Uppsala University, Sweden
    Indoor Air 19:392-400. 2009
    ..The high prevalence of reported dampness/molds and the common occurrence of fungal DNA indicate the need to improve the indoor environment of Swedish day care centers...
  58. ncbi request reprint Effect of smoking on exhaled nitric oxide and flow-independent nitric oxide exchange parameters
    A Malinovschi
    Dept of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Eur Respir J 28:339-45. 2006
    ..The association between snus (oral tobacco) use and reduced nitric oxide concentrations in the airways and increased nitric oxide transfer from the airways warrants further studies...
  59. doi request reprint Oral contraception, body mass index, and asthma: a cross-sectional Nordic-Baltic population survey
    Ferenc Macsali
    Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
    J Allergy Clin Immunol 123:391-7. 2009
    ..Emerging evidence suggests that sex steroid hormones may influence airways obstruction, and that metabolic status may modify potential effects...
  60. doi request reprint Indoor environment in three North European cities in relationship to atopy and respiratory symptoms
    María Ingibjörg Gunnbjörnsdóttir
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Clin Respir J 3:85-94. 2009
    ....
  61. ncbi request reprint Snoring and daytime sleepiness as risk factors for hypertension and diabetes in women--a population-based study
    Eva Lindberg
    Department of Medical Sciences, Respiratory Medicine and Allergology, Akademiska sjukhuset, SE 75185 Uppsala, Sweden
    Respir Med 101:1283-90. 2007
    ..These differences might indicate differences in pathophysiologic mechanisms underlying the association between sleep-disordered breathing and hypertension and diabetes respectively...
  62. pmc Association between Chlamydia pneumoniae antibodies and wheezing in young children and the influence of sex
    E Normann
    Department of Women s and Children s Health, Uppsala University, Sweden
    Thorax 61:1054-8. 2006
    ..The proposed association between Chlamydia pneumoniae (Cpn) infection and wheezing needs further clarification...
  63. doi request reprint Obstructive sleep apnoea is associated with decreased insulin sensitivity in females
    J Theorell-Haglöw
    Dept of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, SE 751 85 Uppsala, Sweden
    Eur Respir J 31:1054-60. 2008
    ..14-0.99 and 95% CI 0.28-6.47, respectively). Obstructive sleep apnoea was found to be independently associated with decreased insulin sensitivity in the present population-based sample of females...
  64. ncbi request reprint Delayed type of hypersensitivity and late allergic reactions in patients with stable COPD
    I Dahlén
    Department of Medical Sciences, Respiratory Medicine, and Allergology, Akademiska sjukhuset, Uppsala University, Sweden
    Chest 116:1625-31. 1999
    ..DTH is known to be and late allergic reaction (LAR) has been suggested to be dependent on T-lymphocyte function...
  65. ncbi request reprint Lung function, respiratory symptoms, and the menopausal transition
    Francisco Gómez Real
    Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
    J Allergy Clin Immunol 121:72-80.e3. 2008
    ..There is limited information on potential changes in respiratory health when women enter the menopausal transition...
  66. pmc Gender differences in the association between C-reactive protein, lung function impairment, and COPD
    Inga Sif Olafsdóttir
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Uppsala, Sweden
    Int J Chron Obstruct Pulmon Dis 2:635-42. 2007
    ..Higher CRP values are significantly associated with COPD and lower lung function in men and women. In men higher CRP values are related to a larger decline in FEV1...
  67. pmc Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen
    Mohammad Alimohammadi
    Department of Medical Sciences, University Hospital, Uppsala University, 751 85 Uppsala, Sweden
    Proc Natl Acad Sci U S A 106:4396-401. 2009
    ..These findings may facilitate the recognition, diagnosis, characterization, and understanding of the pulmonary manifestations of APS-1...
  68. pmc Physical activity and quality of life in subjects with chronic disease: chronic obstructive pulmonary disease compared with rheumatoid arthritis and diabetes mellitus
    Mats Arne
    Primary Care Research Unit, County Council of Varmland, Karlstad, Sweden
    Scand J Prim Health Care 27:141-7. 2009
    ....
  69. doi request reprint How often is diagnosis of COPD confirmed with spirometry?
    Mats Arne
    Primary Care Research Unit, County Council of Varmland, Universitetsgatan 3, SE 656 37, Karlstad, Sweden
    Respir Med 104:550-6. 2010
    ..Diagnosis is customarily confirmed with spirometry, but there are few studies on documented spirometry use in everyday clinical practice...
  70. doi request reprint High BMI is related to higher incidence of asthma, while a fish and fruit diet is related to a lower- Results from a long-term follow-up study of three age groups in Sweden
    Monica Uddenfeldt
    Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
    Respir Med 104:972-80. 2010
    ..52 (0.35-0.77)]. No significant difference was found in the impact of risk factors between men and women. Weight loss, smoking cessation and a diet rich in fruit and fish may be of importance in preventing onset of adult asthma...
  71. doi request reprint Asthma management and asthma control in São Paulo, Brazil and Uppsala, Sweden: a questionnaire-based comparison
    Paul Skorup
    Section for Infectious Diseases, Department of Medical Science, Akademiska sjukhuset, University Hospital, Uppsala, Sweden
    Clin Respir J 3:22-8. 2009
    ..The aim of the present study was to compare asthma management and asthma control in São Paulo, Brazil and Uppsala, Sweden...
  72. ncbi request reprint What are the important risk factors for daytime sleepiness and fatigue in women?
    Jenny Theorell-Haglöw
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Sweden
    Sleep 29:751-7. 2006
    ..To analyze the relation between different risk factors and excessive daytime sleepiness (EDS) and fatigue in women from a general-population sample...
  73. pmc Associations between short sleep duration and central obesity in women
    Jenny Theorell-Haglöw
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Sweden
    Sleep 33:593-8. 2010
    ..The aim was to assess associations between sleep duration, sleep stages, and central obesity in women...
  74. ncbi request reprint Anxiety and depression are related to the outcome of emergency treatment in patients with obstructive pulmonary disease
    Inger Dahlén
    Department of Medical Sciences, Respiratory Medicine, and Allergology, Uppsala University Hospital, Sweden
    Chest 122:1633-7. 2002
    ..To investigate whether psychological factors predict outcome after emergency treatment for obstructive pulmonary disease...
  75. doi request reprint Serum levels of matrix metalloproteinase-9, tissue inhibitors of metalloproteinase-1 and their ratio are associated with impaired lung function in the elderly: a population-based study
    Inga S Olafsdóttir
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University Hospital, SE 751 85 Uppsala, Sweden
    Respirology 15:530-5. 2010
    ..The aim of this study was to investigate the associations of serum MMP-9 and TIMP-1 with lung function...
  76. ncbi request reprint Walking distance is a predictor of exacerbations in patients with chronic obstructive pulmonary disease
    Margareta I Emtner
    Pulmonary Medicine and Allergology, Medical Sciences, Uppsala University, Akademiska sjukhuset, Entrance 50, 751 85 Uppsala, Sweden
    Respir Med 101:1037-40. 2007
    ..Physiological measures of lung function often fail to describe the impact the symptoms have on exacerbations, days of hospitalisation, and on a patient's health...
  77. ncbi request reprint The effect of infectious burden on the prevalence of atopy and respiratory allergies in Iceland, Estonia, and Sweden
    Christer Janson
    Respiratory Medicine and Allergology, Akademiska sjukhuset, Uppsala, Sweden
    J Allergy Clin Immunol 120:673-9. 2007
    ..Epidemiologic reports on the effect of microbe exposure on the development of atopy and allergic asthma are inconsistent...
  78. ncbi request reprint Nutritional status and long-term mortality in hospitalised patients with chronic obstructive pulmonary disease (COPD)
    Runa Hallin
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, SE 751 85 Uppsala, Sweden
    Respir Med 101:1954-60. 2007
    ..Further studies are needed in order to show whether identifying and treating weight loss and depletion of fat-free mass (FFM) is a way forward in improving the prognosis for hospitalised COPD patients...
  79. ncbi request reprint What characterizes patients who are unable to tolerate continuous positive airway pressure (CPAP) treatment?
    C Janson
    Department of Medical sciences Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Sweden
    Respir Med 94:145-9. 2000
    ....
  80. doi request reprint Non-respiratory symptoms and well-being in asthmatics from a general population sample
    Mai Leander
    Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala, University, Uppsala, Sweden
    J Asthma 46:552-9. 2009
    ..The generic instrument Gothenburg Quality of Life (GQL) was used. A secondary aim was to study if GQL had any prognostic value in asthma...
  81. ncbi request reprint Risk factors associated with snoring in women with special emphasis on body mass index: a population-based study
    Malin Svensson
    Otorhinolaryngology and Head and Neck Surgery, Akademiska sjukhuset, SE 751 85 Uppsala, Sweden
    Chest 129:933-41. 2006
    ..Design and setting: A cross-sectional, epidemiologic, population-based study was performed by using a postal questionnaire that was sent to a randomly selected sample of 6,817 women >/= 20 years of age in Uppsala, Sweden...
  82. ncbi request reprint CPAP treatment of a population-based sample--what are the benefits and the treatment compliance?
    Eva Lindberg
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, and Sleep Laboratory, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
    Sleep Med 7:553-60. 2006
    ..Another purpose was to investigate the compliance to CPAP in this population...
  83. ncbi request reprint Nutritional status, dietary energy intake and the risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD)
    Runa Hallin
    Department of Medical Sciences, Respiratory Medicine and Allergology, Uppsala University, Akademiska sjukhuset, Uppsala, Sweden
    Respir Med 100:561-7. 2006
    ..003 and 0.006, respectively). We conclude that, in patients who are hospitalised because of COPD, underweight and weight loss during the follow-up period are related to a higher risk of having new exacerbations...
  84. doi request reprint Basal and induced NO formation in the pharyngo-oral tract influences estimates of alveolar NO levels
    Andrei Malinovschi
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    J Appl Physiol (1985) 106:513-9. 2009
    ..These findings were robust for TMAD...
  85. ncbi request reprint Ultrastructure of bronchial biopsies from patients with allergic and non-allergic asthma
    S Shahana
    Department of Medical Cell Biology, Uppsala University, P O Box 571, SE 75123 Uppsala, Sweden
    Respir Med 99:429-43. 2005
    ..Reduced desmosomal contact may be an important factor in the epithelial shedding observed in patients with asthma...
  86. doi request reprint Health-related quality of life predicts onset of asthma in a longitudinal population study
    Mai Leander
    Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden
    Respir Med 103:194-200. 2009
    ..The purpose of this study was to investigate if a set of quality of life measures could predict onset of asthma...
  87. doi request reprint Associations between mortality, asthma, and health-related quality of life in an elderly cohort of Swedes
    Mai Leander
    Department of Medical Sciences, Occupational and Environmental Medicine, UppsalaUniversity, Uppsala, Sweden
    J Asthma 47:627-32. 2010
    ..The primary aim of this study was to investigate whether low HRQL was a predictor of mortality in elderly subjects and whether such an association differed between subjects with and without asthma...
  88. doi request reprint Experimental and seasonal exposure to birch pollen in allergic rhinitis and allergic asthma with regard to the inflammatory response
    Mary Kämpe
    Department of Medical Sciences, Respiratory Medicine and Allergology, University Hospital, Uppsala, Sweden
    Clin Respir J 4:37-44. 2010
    ..The second aim was to compare the responses of patients with allergic rhinitis and allergic asthma, respectively to both types of allergen exposure...
  89. ncbi request reprint The relation of adult bronchial responsiveness to serious childhood respiratory illness in the ECRHS
    Susan Chinn
    Department Public Health Sciences, King s College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK
    Respir Med 101:983-8. 2007
    ..Respiratory symptoms in adulthood have been found to be associated with childhood respiratory infection, but few studies have analyzed adult bronchial responsiveness (BHR) with adequate adjustment for known risk factors...
  90. pmc Physical activity and bronchial hyperresponsiveness: European Community Respiratory Health Survey II
    Rafea Shaaban
    INSERM U700, Epidémiologie des Maladies Respiratoires, Faculte Xavier Bichat, BP 416, 16 rue Henri Huchard, 75018 Paris, France
    Thorax 62:403-10. 2007
    ..The relationship between physical activity and BHR in men and women aged 28.0-56.5 years randomly selected from 24 centres in 11 countries participating in the European Community Respiratory Health Survey II was investigated...
  91. ncbi request reprint Perennial non-infectious rhinitis--an independent risk factor for sleep disturbances in Asthma
    Johan Hellgren
    Department of Oto Rhino Laryngology and Head and Neck Surgery, Lundby Hospital, Goteborg, Sweden
    Respir Med 101:1015-20. 2007
    ..To evaluate if perennial non-infectious rhinitis is associated with sleep disturbances in asthma...
  92. ncbi request reprint Incidence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm
    Roberto de Marco
    Sezione di Epidemiologia and Statistica Medica, Dipartimento di Medicina e Sanita Pubblica, Universita degli Studi di Verona, c o Istituti Biologici II, Strada Le Grazie 8 37134, Verona, Italy
    Am J Respir Crit Care Med 175:32-9. 2007
    ..The few prospective studies aimed at assessing the incidence of chronic obstructive pulmonary disease (COPD) in relation to the presence of chronic cough/phlegm have produced contrasting results...
  93. ncbi request reprint An increase in bronchial responsiveness is associated with continuing or restarting smoking
    Susan Chinn
    Department of Public Health Sciences, King s College London, London, UK
    Am J Respir Crit Care Med 172:956-61. 2005
    ..Bronchial responsiveness (BHR) has been found to be associated with smoking, atopy, and lower lung function in cross-sectional studies, but there is little information on determinants of change in adults...
  94. ncbi request reprint Seroprevalence of Helicobacter pylori and cagA antibodies in Iceland, Estonia and Sweden
    Bjarni Thjodleifsson
    Medical Department, Landspitali University Hospital, Iceland
    Scand J Infect Dis 39:683-9. 2007
    ..Overall, socioeconomic development during the childhood period seems to be the most important factor for the prevalence of H. pylori infection. In adults, smoking may be a contributory factor...
  95. ncbi request reprint Respiratory symptoms and nocturnal gastroesophageal reflux: a population-based study of young adults in three European countries
    Thorarinn Gislason
    Department of Lung Medicine, Vifilsstadir Hospital, Gardabaer, Iceland
    Chest 121:158-63. 2002
    ..To estimate the possible association between reported symptoms of gastroesophageal reflux (GER) after bedtime, sleep-disordered breathing, respiratory symptoms, and asthma...
  96. ncbi request reprint Prognostic factors of asthma severity: a 9-year international prospective cohort study
    Roberto de Marco
    University of Verona, Department of Medicine and Public Health, Unit of Epidemiology and Medical Statistics, Verona, Italy
    J Allergy Clin Immunol 117:1249-56. 2006
    ..The natural history of asthma severity is poorly known...
  97. ncbi request reprint The control of asthma in Italy. A multicentre descriptive study on young adults with doctor diagnosed current asthma
    Roberto de Marco
    Unit of Epidemiology and Medical Statistics, University of Verona, Verona, Italy
    Allergy 58:221-8. 2003
    ..Few data are available on the management of asthma in the general population. The aim of this study was to evaluate the level of asthma control in Italian patients, a decade after the publication of the international guidelines...
  98. ncbi request reprint The prevalence and predictors of respiratory-related work limitation and occupational disability in an international study
    Paul D Blanc
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco, 350 Parnassus Avenue, No 609, San Francisco, CA 94117, USA
    Chest 124:1153-9. 2003
    ..To investigate this problem, we analyzed data on respiratory symptoms related to the workplace and occupational disability from the European Community Respiratory Health Survey (ECRHS)...
  99. ncbi request reprint Smoking cessation, lung function, and weight gain: a follow-up study
    Susan Chinn
    Department of Public Health Sciences, King s College London, 5th Floor Capital House, 42 Weston Street, London SE1 3QD, UK
    Lancet 365:1629-35; discussion 1600-1. 2005
    ..We estimated the net benefit of smoking cessation, and the independent effects of smoking and weight change on change in ventilatory lung function in the international European Community Respiratory Health Survey...
  100. ncbi request reprint Asthma control in Europe: a real-world evaluation based on an international population-based study
    Lucia Cazzoletti
    Unit of Epidemiology and Medical Statistics, Department of Medicine and Public Health, University of Verona, Verona, Italy
    J Allergy Clin Immunol 120:1360-7. 2007
    ..Epidemiologic evidence related to asthma control in patients from the general population is scanty...
  101. ncbi request reprint Menstrual irregularity and asthma and lung function
    Francisco Gómez Real
    Environmental Respiratory Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
    J Allergy Clin Immunol 120:557-64. 2007
    ..Oligomenorrhea was associated with more asthma (Respiratory Health in Northern Europe study), but a possible association with lung function has not been investigated previously...