Research Topics
Genomes and Genes | S IwataSummaryAffiliation: Uppsala University Country: Sweden Publications
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Publications
Structure and function of bacterial cytochrome c oxidaseS Iwata
Uppsala University, Department of Biochemistry, Biomedical Center, BOX 756 S 75123 Uppsala, Sweden
J Biochem 123:369-75. 1998..Structural features of Paracoccus oxidase have been summarized in the light of these mutagenesis studies and other structural works...- Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complexS Iwata
Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA
Science 281:64-71. 1998..These "core" subunits are related to the matrix processing peptidase, and the structure unveils how mitochondrial targeting presequences are recognized... - Structure of cytochrome c oxidase: a comparison of the bacterial and mitochondrial enzymesJ Abramson
Department of Biochemistry, Upssala Univeristy, Biomedical Center, Sweden
Biochim Biophys Acta 1544:1-9. 2001..In this article, we revisit the original structures of bacterial and mitochondrial oxidases and try to clarify similarities as well as differences between the two structures... - The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding siteJ Abramson
Uppsala University, Department of Biochemistry, Biomedical Center Box 576, Uppsala S 75123, Sweden
Nat Struct Biol 7:910-7. 2000..In light of these findings we suggest specific roles for these polar residues in electron and proton transfer in ubiquinol oxidase... - T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric controlS Iwata
Department of Agricultural Chemistry, University of Tokyo, Japan
Nat Struct Biol 1:176-85. 1994..The proposed mechanism can explain activation by chemical modification and mutagenesis, as well as suggesting why vertebrate counterparts are not allosteric... - A regular 1:1 complex of two allosteric states in the single crystal of L-lactate dehydrogenase from Bifidobacterium longumS Iwata
Department of Agricultural Chemistry, University of Tokyo, Japan
J Mol Biol 236:958-9. 1994..5 A spacing. A crystallographic study showed that the asymmetric unit contains two subunits and that one of them belongs to the T-state tetramer and the other to the R-state tetramer... - Structure of a water soluble fragment of the 'Rieske' iron-sulfur protein of the bovine heart mitochondrial cytochrome bc1 complex determined by MAD phasing at 1.5 A resolutionS Iwata
Max Planck Institut fur Biophysik, Abt Molekulare Membranbiologie, Frankfurt Main, Germany
Structure 4:567-79. 1996..A 129-residue water soluble fragment containing the intact [2Fe-2S] cluster was isolated following proteolytic digestion of the bc1 complex and used for structural studies... - Purification, crystallization and preliminary crystallographic studies of an integral membrane protein, cytochrome bo3 ubiquinol oxidase from Escherichia coliJ Abramson
Uppsala University Department of Biochemistry, BMC BOX 576, S 75123 Uppsala, Sweden
Acta Crystallogr D Biol Crystallogr 56:1076-8. 2000.... - Enamel tensile bond strength and morphology of resin-enamel interface created by acid etching system with or without moisture and self-etching priming systemY Torii
Department of Operative Dentistry, Okayama University Dental School, Japan
J Oral Rehabil 29:528-33. 2002..These results indicate that the traditional system with phosphoric acid etching exhibits the most stable enamel adhesion although the enamel-bonding promoting abilities of these adhesive systems are equivalent to each other... - Demonstration of the interaction of thioredoxin with p40phox, a phagocyte oxidase component, using a yeast two-hybrid systemA Nishiyama
Department of Biological Responses, Institute for Virus Research, Kyoto University, Sakyo, Japan
Immunol Lett 68:155-9. 1999..These results showed that p40phox interacts with TRX and indicated the possibility of TRX-dependent regulation of phagocyte oxidase activity... - Crystallization of and preliminary crystallographic data for allosteric L-lactate dehydrogenase from Bifidobacterium longumS Iwata
Department of Agricultural Chemistry, University of Tokyo
J Biochem 106:558-9. 1989..8 A. Those of the type III and type IV crystals were a = 106.4 A, b = 131.4 A, and c = 63.8 A. The type III crystals diffract X-rays to beyond 2.5 A spacing. The type II and type III crystals were stable as to X-ray irradiation... 
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1K Hirota
Department of Anesthesia, Kyoto University Hospital, Japan
Proc Natl Acad Sci U S A 94:3633-8. 1997..This report presents an example of a cascade in cellular redox regulation...- Molecular basis of allosteric activation of bacterial L-lactate dehydrogenaseS Iwata
Photon Factory, National Laboratory for High Energy Physics, Ibaraki Ken, Japan
J Mol Biol 230:21-7. 1993..This T to R transition is the first example for a tetrameric allosteric protein where the rotations occur around each of three axes of symmetry... - A furin-defective cell line is able to process correctly the gp160 of human immunodeficiency virus type 1Y Ohnishi
Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Japan
J Virol 68:4075-9. 1994..Our present study thus raises a further need to search for and identify the proteinases involved in human immunodeficiency virus type 1 gp160 processing rather than supporting the notion that furin is responsible... - Prooxidant action of gallic acid compounds: copper-dependent strand breaks and the formation of 8-hydroxy-2'-deoxyguanosine in DNAM Yoshino
Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi 480 1195, Japan
Toxicol In Vitro 16:705-9. 2002..The cytotoxic effect of gallate compounds can be explained by their prooxidant action dependent on the reducing activity...