Erik Ingellson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study
    Christopher J O'Donnell
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S4. 2007
  2. ncbi Polymorphisms in the estrogen receptor alpha gene and endothelial function in resistance and conduit arteries in the elderly
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Atherosclerosis 199:162-71. 2008
  3. doi Endothelium-dependent vasodilation in conduit and resistance vessels in relation to the endothelial nitric oxide synthase gene
    E Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    J Hum Hypertens 22:569-78. 2008
  4. doi Inflammatory markers in relation to insulin resistance and the metabolic syndrome
    E Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Eur J Clin Invest 38:502-9. 2008
  5. pmc The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    BMC Cardiovasc Disord 8:37. 2008
  6. ncbi Sleep disturbances independently predict heart failure in overweight middle-aged men
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Eur J Heart Fail 9:184-90. 2007
  7. ncbi Diurnal blood pressure pattern and risk of congestive heart failure
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    JAMA 295:2859-66. 2006
  8. pmc Metabolic syndrome and risk for heart failure in middle-aged men
    E Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Heart 92:1409-13. 2006
  9. ncbi The validity of a diagnosis of heart failure in a hospital discharge register
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Box 609, SE 75125 Uppsala, Sweden
    Eur J Heart Fail 7:787-91. 2005
  10. ncbi Novel metabolic risk factors for heart failure
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    J Am Coll Cardiol 46:2054-60. 2005

Detail Information

Publications46

  1. pmc Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study
    Christopher J O'Donnell
    The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
    BMC Med Genet 8:S4. 2007
    ..We conducted a genome-wide association study (GWAS) for SCA measurements in the community-based Framingham Heart Study...
  2. ncbi Polymorphisms in the estrogen receptor alpha gene and endothelial function in resistance and conduit arteries in the elderly
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Atherosclerosis 199:162-71. 2008
    ..Our aim was to examine the relations of single nucleotide polymorphisms (SNPs) in the estrogen receptor alpha gene (ESR1) to endothelium-dependent vasodilation...
  3. doi Endothelium-dependent vasodilation in conduit and resistance vessels in relation to the endothelial nitric oxide synthase gene
    E Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    J Hum Hypertens 22:569-78. 2008
    ..This SNP has previously been related to coronary heart disease, and our findings should stimulate to replication and exploration of the association of NOS3 variation with endothelial function in other settings...
  4. doi Inflammatory markers in relation to insulin resistance and the metabolic syndrome
    E Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    Eur J Clin Invest 38:502-9. 2008
    ..Inflammation has repeatedly been demonstrated to be associated with the metabolic syndrome (MetS) and insulin resistance, but the relative importance of different aspects of the inflammatory process is largely unexplored...
  5. pmc The PPARGC1A Gly482Ser polymorphism is associated with left ventricular diastolic dysfunction in men
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    BMC Cardiovasc Disord 8:37. 2008
    ....
  6. ncbi Sleep disturbances independently predict heart failure in overweight middle-aged men
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Eur J Heart Fail 9:184-90. 2007
    ..Sleep disturbances are associated with manifest heart failure (HF). However, the relationship between sleep disturbances and incident HF has been less studied...
  7. ncbi Diurnal blood pressure pattern and risk of congestive heart failure
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    JAMA 295:2859-66. 2006
    ..High blood pressure is the most important risk factor for congestive heart failure (CHF) at a population level, but the relationship of an altered diurnal blood pressure pattern to risk of subsequent CHF is unknown...
  8. pmc Metabolic syndrome and risk for heart failure in middle-aged men
    E Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala Science Park, SE 751 85 Uppsala, Sweden
    Heart 92:1409-13. 2006
    ..To explore metabolic syndrome as a possible risk factor for development of heart failure (HF)...
  9. ncbi The validity of a diagnosis of heart failure in a hospital discharge register
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Box 609, SE 75125 Uppsala, Sweden
    Eur J Heart Fail 7:787-91. 2005
    ..The accuracy of a diagnosis of heart failure (HF) in hospital discharge registers is largely unknown. We aimed to determine the validity of such a diagnosis in the Swedish hospital discharge register...
  10. ncbi Novel metabolic risk factors for heart failure
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    J Am Coll Cardiol 46:2054-60. 2005
    ..Our objectives were to explore novel metabolic risk factors for development of heart failure (HF)...
  11. ncbi Insulin resistance and risk of congestive heart failure
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    JAMA 294:334-41. 2005
    ..Diabetes and obesity are established risk factors for congestive heart failure (CHF) and are both associated with insulin resistance...
  12. ncbi Inflammation, as measured by the erythrocyte sedimentation rate, is an independent predictor for the development of heart failure
    Erik Ingelsson
    Public Health and Caring Sciences, Uppsala, Sweden
    J Am Coll Cardiol 45:1802-6. 2005
    ..Our objective was to explore inflammation, measured as erythrocyte sedimentation rate (ESR), as a predictor for the development of heart failure (HF)...
  13. pmc Serum cystatin C and the risk of Alzheimer disease in elderly men
    J Sundelof
    Uppsala University, Department of Public Health Geriatrics, Uppsala Science Park, Uppsala, Sweden
    Neurology 71:1072-9. 2008
    ..Multiple lines of research suggest that increased cystatin C activity in the brain protects against the development of Alzheimer disease (AD)...
  14. ncbi Relative importance and conjoint effects of obesity and physical inactivity for the development of insulin resistance
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur J Cardiovasc Prev Rehabil 16:28-33. 2009
    ..Obesity and physical inactivity are related to the development of insulin resistance, but their relative importance and conjoint effects are unclear...
  15. pmc Altered blood pressure progression in the community and its relation to clinical events
    Erik Ingelsson
    Framingham Heart Study, 73 Mount Wayte Ave, Ste 2, Framingham, MA 01702 5803, USA
    Arch Intern Med 168:1450-7. 2008
    ..Long-term blood pressure (BP) progression and its importance as a predictor of clinical outcome have not been well characterized across different periods...
  16. ncbi Risk associated with the metabolic syndrome versus the sum of its individual components
    Johan Sundstrom
    Department of Medical Sciences, Uppsala University Hospital, SE 751 85 Uppsala, Sweden
    Diabetes Care 29:1673-4. 2006
  17. doi Use of multiple biomarkers to improve the prediction of death from cardiovascular causes
    Bjorn Zethelius
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    N Engl J Med 358:2107-16. 2008
    ..The incremental usefulness of adding multiple biomarkers from different disease pathways for predicting the risk of death from cardiovascular causes has not, to our knowledge, been evaluated among the elderly...
  18. doi Plasma parathyroid hormone and the risk of cardiovascular mortality in the community
    Emil Hagström
    Uppsala Clinical Research Center, Uppsala University, Sweden
    Circulation 119:2765-71. 2009
    ..However, data on the prospective association between circulating PTH levels and cardiovascular mortality in the community are lacking...
  19. ncbi Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study
    Erik Ingelsson
    Framingham Heart Study, Boston University School of Medicine, Framingham, MA 01702 5803, USA
    Circulation 116:984-92. 2007
    ..We evaluated the relative contributions of circulating biomarkers representing distinct biological pathways to the incidence of MetS and to longitudinal changes of its constituent risk factors...
  20. doi Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study
    Johan Sundelöf
    Uppsala University, Department of Public Health and Geriatrics, Uppsala Science Park, Dag Hammarskölds väg 14B, Uppsala, Sweden
    Arch Neurol 65:256-63. 2008
    ..Beta amyloid (Abeta) protein accumulates in the brains of individuals with Alzheimer disease (AD) and is detectable in cerebrospinal fluid and plasma...
  21. pmc Impact of BMI and the metabolic syndrome on the risk of diabetes in middle-aged men
    Johan Arnlov
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
    Diabetes Care 34:61-5. 2011
    ..We aimed to investigate associations between combinations of BMI categories and metabolic syndrome and risk of type 2 diabetes in middle-aged men...
  22. doi Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men
    Johan Arnlov
    Department of Public Health and Caring Sciences Geriatrics, Uppsala University, SE 751 85 Uppsala, Sweden
    Circulation 121:230-6. 2010
    ..The purpose of this study was to investigate associations between combinations of body mass index (BMI) categories and metabolic syndrome (MetS) and the risk of cardiovascular disease and death in middle-aged men...
  23. ncbi Alcohol intake, insulin resistance, and abdominal obesity in elderly men
    Ulf Riserus
    Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism Geriatrics, Uppsala Science Park, 751 85 Uppsala, Sweden
    Obesity (Silver Spring) 15:1766-73. 2007
    ..Insulin resistance, insulin secretion, and abdominal obesity are major predictors of diabetes, but the links with alcohol intake remain contradictory because of limited data...
  24. ncbi Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity
    Eva Warensjo
    Clinical Nutrition and Metabolism, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, 751 85 Uppsala, Sweden
    Obesity (Silver Spring) 15:1732-40. 2007
    ..Further, SCD1-deficent mice are protected against obesity and insulin resistance. We hypothesized that genetic polymorphisms in the SCD1 gene would be associated with obesity, insulin sensitivity, and estimated SCD activity in humans...
  25. doi Conjoint effects of serum calcium and phosphate on risk of total, cardiovascular, and noncardiovascular mortality in the community
    Tobias E Larsson
    Department of Nephrology, Karolinska University Hospital, Stockholm, Sweden
    Arterioscler Thromb Vasc Biol 30:333-9. 2010
    ..Hyperphosphatemia is a cardiovascular risk factor in patients with chronic kidney disease. Relations of circulating calcium (Ca) and phosphorus (Pi) to long-term mortality risk in the community require further investigation...
  26. ncbi Myocardial performance index, a Doppler-derived index of global left ventricular function, predicts congestive heart failure in elderly men
    Johan Arnlov
    Department of Public Health and Caring Sciences, Section of Geriatrics, Uppsala University, Uppsala, Sweden
    Eur Heart J 25:2220-5. 2004
    ..Myocardial performance index (MPI, also denoted TEI-Doppler index) reflects both left ventricular (LV) systolic and diastolic function...
  27. pmc Aortic root diameter and longitudinal blood pressure tracking
    Erik Ingelsson
    Framingham Heart Study, Boston University School of Medicine, Framingham, Massachusetts 01702 5803, USA
    Hypertension 52:473-7. 2008
    ..Our prospective study does not support the notion that a smaller AoR predisposes to hypertension...
  28. doi Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Atherosclerosis 206:239-44. 2009
    ..Our aim was to examine relations of serum retinol-binding protein 4 (RBP4) to cardiovascular risk factors, and prevalent metabolic syndrome (MetS) and cardiovascular disease (CVD) in a large community-based sample of elderly...
  29. ncbi Low-grade albuminuria and the incidence of heart failure in a community-based cohort of elderly men
    Erik Ingelsson
    Section of Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala Science Park, Uppsala, Sweden
    Eur Heart J 28:1739-45. 2007
    ..To investigate associations of urinary albumin excretion rate (UAER) and heart failure (HF) incidence in a community-based sample...
  30. doi Cardiac troponin-I and risk of heart failure: a community-based cohort study
    Johan Sundstrom
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Eur Heart J 30:773-81. 2009
    ..We examined if circulating levels of cardiac troponin-I (cTnI) predict subsequent heart failure in the community...
  31. doi Adiponectin and cardiac geometry and function in elderly: results from two community-based cohort studies
    Stefan Gustafsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
    Eur J Endocrinol 162:543-50. 2010
    ..Our objective was to investigate such associations in two large community-based studies of elderly...
  32. pmc Insulin sensitivity measured with euglycemic clamp is independently associated with glomerular filtration rate in a community-based cohort
    Elisabet Nerpin
    Department of Health and Social Sciences, Högskolan Dalarna, Falun, Sweden
    Diabetes Care 31:1550-5. 2008
    ..To investigate the association between insulin sensitivity and glomerular filtration rate (GFR) in the community, with prespecified subgroup analyses in normoglycemic individuals with normal GFR...
  33. ncbi Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes
    Erik Ingelsson
    National Heart, Lung, and Blood Institute s Framingham Study, Framingham, Massachusetts 01702 5803, USA
    Diabetes 56:1718-26. 2007
    ..93 [1.15-3.24]). In our community-based sample, individuals with MetS have a high prevalence of subclinical atherosclerosis that likely contributes to the increased risk of overt CVD associated with the condition...
  34. ncbi Clinical correlates of circulating visfatin levels in a community-based sample
    Erik Ingelsson
    Framingham Study, Boston University School of Medicine, Framingham, Massachusetts, Framingham, MA 01702 5803, USA
    Diabetes Care 30:1278-80. 2007
  35. pmc Vitamin D deficiency and risk of cardiovascular disease
    Thomas J Wang
    Framingham Heart Study, Framingham, Mass, USA
    Circulation 117:503-11. 2008
    ..A growing body of evidence suggests that vitamin D deficiency may adversely affect the cardiovascular system, but data from longitudinal studies are lacking...
  36. ncbi Socioeconomic factors as predictors of incident heart failure
    Erik Ingelsson
    Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
    J Card Fail 12:540-5. 2006
    ..Further, it is unknown if these factors predict incident HF independently of myocardial infarction and other established risk factors for HF...
  37. pmc Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes 59:1266-75. 2010
    ..Our findings emphasize the importance of detailed physiological characterization of such loci for improved understanding of pathways associated with alterations in glucose homeostasis and eventually type 2 diabetes...
  38. doi Associations of circulating adiponectin with measures of vascular function and morphology
    Stefan Gustafsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    J Clin Endocrinol Metab 95:2927-34. 2010
    ....
  39. pmc Circulating retinol-binding protein 4 and subclinical cardiovascular disease in the elderly
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes Care 32:733-5. 2009
    ..We evaluated associations of serum retinol-binding protein 4 (RBP4) with subclinical cardiovascular disease (CVD)...
  40. ncbi Heritability, linkage, and genetic associations of exercise treadmill test responses
    Erik Ingelsson
    Framingham Study, Framingham, Mass, USA
    Circulation 115:2917-24. 2007
    ..The blood pressure (BP) and heart rate responses to exercise treadmill testing predict incidence of cardiovascular disease, but the genetic determinants of hemodynamic and chronotropic responses to exercise are largely unknown...
  41. pmc Circulating ghrelin, leptin, and soluble leptin receptor concentrations and cardiometabolic risk factors in a community-based sample
    Erik Ingelsson
    The Framingham Study, Boston University School of Medicine, Framingham, Massachusetts 01702 5803, USA
    J Clin Endocrinol Metab 93:3149-57. 2008
    ..The conjoint effects and relative importance of ghrelin, leptin, and soluble leptin receptor (sOB-R), adipokines involved in appetite control and energy expenditure in mediating cardiometabolic risk, is unknown...
  42. ncbi Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals
    Erik Ingelsson
    Framingham Heart Study, 73 Mount Wayte Ave, Framingham, MA 01702 5803, USA
    Circulation 116:375-84. 2007
    ..The burden and prognostic importance of subclinical cardiovascular disease (CVD) in obesity has not been investigated systematically...
  43. doi Effects of trans10cis12CLA-induced insulin resistance on retinol-binding protein 4 concentrations in abdominally obese men
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Diabetes Res Clin Pract 82:e23-4. 2008
    ..Further, there were no associations between CLA-induced insulin resistance and changes in RBP4...
  44. ncbi Adiponectin and risk of congestive heart failure
    Erik Ingelsson
    JAMA 295:1772-4. 2006
  45. ncbi Clinical utility of different lipid measures for prediction of coronary heart disease in men and women
    Erik Ingelsson
    Framingham Heart Study, 73 Mount Wayte Ave, Suite 2, Framingham, MA 01702 5803
    JAMA 298:776-85. 2007
    ..Evidence is conflicting regarding the performance of apolipoproteins vs traditional lipids for predicting coronary heart disease (CHD) risk...
  46. ncbi Associations of serum adiponectin with skeletal muscle morphology and insulin sensitivity
    Erik Ingelsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden
    J Clin Endocrinol Metab 94:953-7. 2009
    ..Skeletal muscle morphology and function are strongly associated with insulin sensitivity...