Michael Hultström

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. doi Collagen-binding proteins in age-dependent changes in renal collagen turnover: microarray analysis of mRNA expression
    Michael Hultström
    Renal Research Group, Institute of Medicine, University of Bergen, Sweden
    Physiol Genomics 44:576-86. 2012
  2. doi Development of structural kidney damage in spontaneously hypertensive rats
    Michael Hultström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    J Hypertens 30:1087-91. 2012
  3. doi Nitric oxide in afferent arterioles after uninephrectomy depends on extracellular L-arginine
    Frank Helle
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Am J Physiol Renal Physiol 304:F1088-98. 2013
  4. doi Arterial damage precedes the development of interstitial damage in the nonclipped kidney of two-kidney, one-clip hypertensive rats
    Trude Skogstrand
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    J Hypertens 31:152-9. 2013
  5. doi Norepinephrine increases calcium sensitivity of mouse afferent arteriole, thereby enhancing angiotensin II-mediated vasoconstriction
    En Yin Lai
    Division of Physiology, Department of Medical Cell Biology, University of Uppsala, Uppsala, Sweden
    Kidney Int 76:953-9. 2009
  6. doi Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats
    Liliana Monica Bivol
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Am J Physiol Regul Integr Comp Physiol 295:R1866-73. 2008
  7. pmc Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats
    Sabine Leh
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Virchows Arch 459:99-108. 2011
  8. doi Identification of a common molecular pathway in hypertensive renal damage: comparison of rat and human gene expression profiles
    Trude Skogstrand
    aRenal Research Group, Department of Clinical Medicine bDepartment of Biomedicine, University of Bergen cDepartment of Pathology, Haukeland University Hospital, Bergen, Norway dInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK eDepartment of Medicine, Haukeland University Hospital, Bergen, Norway fIntegrative Physiology, Department of Medical Cell Biology gAnaesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden Deceased Martin W McBride and Michael Hultström are co senior authors
    J Hypertens 33:584-96; discussion 596. 2015
  9. doi Distinct protein signature of hypertension-induced damage in the renal proteome of the two-kidney, one-clip rat model
    Heidrun Vethe
    aDepartment of Clinical Medicine bDepartment of Biomedicine, University of Bergen cDepartment of Medicine, Haukeland University Hospital, Bergen dDepartment of Medicine, Haugesund Hospital, Haugesund, Norway eIntegrative Physiology, Department of Medical Cell Biology fAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden gINSERM U702, Hopital Tenon, Paris, France hSpheromics, Kontiolahti, Finland
    J Hypertens 33:126-35. 2015
  10. doi Angiotensin II-induced contraction is attenuated by nitric oxide in afferent arterioles from the nonclipped kidney in 2K1C
    Frank Helle
    Renal Research Group, Institute of Medicine, University of Bergen, N 5021 Bergen, Norway
    Am J Physiol Renal Physiol 296:F78-86. 2009

Collaborators

Detail Information

Publications10

  1. doi Collagen-binding proteins in age-dependent changes in renal collagen turnover: microarray analysis of mRNA expression
    Michael Hultström
    Renal Research Group, Institute of Medicine, University of Bergen, Sweden
    Physiol Genomics 44:576-86. 2012
    ..Collagen stabilizing proteins may be essential for the control of renal ECM turnover and the pathogenesis of kidney fibrosis...
  2. doi Development of structural kidney damage in spontaneously hypertensive rats
    Michael Hultström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    J Hypertens 30:1087-91. 2012
    ..Finally, the mechanism by which reduced tubular flow leads to tubular atrophy is another important area for future research. Initial findings indicate that cilia activation may be of major importance for maintaining tubular structure...
  3. doi Nitric oxide in afferent arterioles after uninephrectomy depends on extracellular L-arginine
    Frank Helle
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Am J Physiol Renal Physiol 304:F1088-98. 2013
    ..In conclusion, NO-dependent hyperperfusion of the remaining kidney in early UNX is associated with increased NO release from the afferent arteriole, which is highly dependent on extracellular L-arginine availability...
  4. doi Arterial damage precedes the development of interstitial damage in the nonclipped kidney of two-kidney, one-clip hypertensive rats
    Trude Skogstrand
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    J Hypertens 31:152-9. 2013
    ..In other hypertensive models, damage has been found to progress from the juxtamedullary cortex (JMC) and outward, which has been attributed to early vascular effects...
  5. doi Norepinephrine increases calcium sensitivity of mouse afferent arteriole, thereby enhancing angiotensin II-mediated vasoconstriction
    En Yin Lai
    Division of Physiology, Department of Medical Cell Biology, University of Uppsala, Uppsala, Sweden
    Kidney Int 76:953-9. 2009
    ....
  6. doi Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats
    Liliana Monica Bivol
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Am J Physiol Regul Integr Comp Physiol 295:R1866-73. 2008
    ..Overall, these results indicate that, after 6 wk of treatment, TTA downregulated the COX2 activity, which have potentially important effects on the regulation of renal hemodynamics but does not explain TTAs ability to lower BP...
  7. pmc Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats
    Sabine Leh
    Renal Research Group, Institute of Medicine, University of Bergen, Bergen, Norway
    Virchows Arch 459:99-108. 2011
    ..Our data suggest that afferent arteriolopathy leads to glomerular collapse and reduced urinary flow with subsequent tubular atrophy...
  8. doi Identification of a common molecular pathway in hypertensive renal damage: comparison of rat and human gene expression profiles
    Trude Skogstrand
    aRenal Research Group, Department of Clinical Medicine bDepartment of Biomedicine, University of Bergen cDepartment of Pathology, Haukeland University Hospital, Bergen, Norway dInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK eDepartment of Medicine, Haukeland University Hospital, Bergen, Norway fIntegrative Physiology, Department of Medical Cell Biology gAnaesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden Deceased Martin W McBride and Michael Hultström are co senior authors
    J Hypertens 33:584-96; discussion 596. 2015
    ..There is a common structural progression in hypertensive renal damage with early arterial damage and fibrosis in the juxtamedullary cortex...
  9. doi Distinct protein signature of hypertension-induced damage in the renal proteome of the two-kidney, one-clip rat model
    Heidrun Vethe
    aDepartment of Clinical Medicine bDepartment of Biomedicine, University of Bergen cDepartment of Medicine, Haukeland University Hospital, Bergen dDepartment of Medicine, Haugesund Hospital, Haugesund, Norway eIntegrative Physiology, Department of Medical Cell Biology fAnaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden gINSERM U702, Hopital Tenon, Paris, France hSpheromics, Kontiolahti, Finland
    J Hypertens 33:126-35. 2015
    ..In the present exploratory study, we investigated experimental nephrosclerosis in the two-kidney, one-clip (2K1C) hypertensive rat model...
  10. doi Angiotensin II-induced contraction is attenuated by nitric oxide in afferent arterioles from the nonclipped kidney in 2K1C
    Frank Helle
    Renal Research Group, Institute of Medicine, University of Bergen, N 5021 Bergen, Norway
    Am J Physiol Renal Physiol 296:F78-86. 2009
    ..In conclusion, the Ca(i)(2+) and contractile responses to ANG II are blunted by NO release in the nonclipped kidney. This may protect the nonclipped kidney from the hypertension and elevated ANG II levels in 2K1C...