Lars Holmberg

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi request reprint Coffee, tea, and caffeine consumption and breast cancer incidence in a cohort of Swedish women
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Ann Epidemiol 12:21-6. 2002
  2. pmc Differences in management of older women influence breast cancer survival: results from a population-based database in Sweden
    Sonja Eaker
    Regional Oncologic Centre ROC, University Hospital, SE 751 85 Uppsala, Sweden
    PLoS Med 3:e25. 2006
  3. ncbi request reprint [Insufficient studies of diagnostic cancer tests. Neither systematic review nor original studies come up to expectations]
    Lars Holmberg
    Regionalt onkologiskt centrum, Akademiska sjukhuset, Uppsala
    Lakartidningen 104:1308-9. 2007
  4. ncbi request reprint Prognostic markers under watchful waiting and radical prostatectomy
    Lars Holmberg
    Regional Oncologic Center, University Hospital, Uppsala, Sweden
    Hematol Oncol Clin North Am 20:845-55. 2006
  5. ncbi request reprint Reducing cancer drug doses in obese patients: dogma disputed
    Lars Holmberg
    Regional Oncologic Centre, University Hospital, S 751 85 Uppsala, Sweden
    Lancet 366:1056-7. 2005
  6. pmc Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial
    Anna Bill-Axelson
    Department of Urology, University Hospital, Uppsala, Sweden
    J Natl Cancer Inst 100:1144-54. 2008
  7. doi request reprint Radical prostatectomy versus watchful waiting in early prostate cancer
    Anna Bill-Axelson
    Department of Urology, University Hospital, Uppsala, Sweden
    N Engl J Med 364:1708-17. 2011
  8. ncbi request reprint Radical prostatectomy versus watchful waiting in early prostate cancer
    Anna Bill-Axelson
    Department of Urology, University Hospital, Uppsala, Sweden
    N Engl J Med 352:1977-84. 2005
  9. doi request reprint Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trial
    Eva Johansson
    Department of Surgical Sciences, University Hospital of Uppsala, Uppsala, Sweden
    Lancet Oncol 12:891-9. 2011
  10. doi request reprint Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation
    Johan Botling
    Departments of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
    Clin Cancer Res 19:194-204. 2013

Detail Information

Publications69

  1. ncbi request reprint Coffee, tea, and caffeine consumption and breast cancer incidence in a cohort of Swedish women
    Karin B Michels
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Ann Epidemiol 12:21-6. 2002
    ..Prior epidemiologic evidence has not supported an overall association between consumption of caffeinated beverages and risk of breast cancer, but consumption in some studies was low...
  2. pmc Differences in management of older women influence breast cancer survival: results from a population-based database in Sweden
    Sonja Eaker
    Regional Oncologic Centre ROC, University Hospital, SE 751 85 Uppsala, Sweden
    PLoS Med 3:e25. 2006
    ..We sought to investigate whether differences in the management of older women with breast cancer are associated with survival...
  3. ncbi request reprint [Insufficient studies of diagnostic cancer tests. Neither systematic review nor original studies come up to expectations]
    Lars Holmberg
    Regionalt onkologiskt centrum, Akademiska sjukhuset, Uppsala
    Lakartidningen 104:1308-9. 2007
  4. ncbi request reprint Prognostic markers under watchful waiting and radical prostatectomy
    Lars Holmberg
    Regional Oncologic Center, University Hospital, Uppsala, Sweden
    Hematol Oncol Clin North Am 20:845-55. 2006
    ..Because overall prognostic information obtained by these parameters or by tumor stage was not provided in our publication, we now present these data in the two study arms separately...
  5. ncbi request reprint Reducing cancer drug doses in obese patients: dogma disputed
    Lars Holmberg
    Regional Oncologic Centre, University Hospital, S 751 85 Uppsala, Sweden
    Lancet 366:1056-7. 2005
  6. pmc Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial
    Anna Bill-Axelson
    Department of Urology, University Hospital, Uppsala, Sweden
    J Natl Cancer Inst 100:1144-54. 2008
    ..In 2005, we reported that radical prostatectomy improved prostate cancer survival compared with watchful waiting after a median of 8.2 years of follow-up. We now report results after 3 more years of follow-up...
  7. doi request reprint Radical prostatectomy versus watchful waiting in early prostate cancer
    Anna Bill-Axelson
    Department of Urology, University Hospital, Uppsala, Sweden
    N Engl J Med 364:1708-17. 2011
    ..In 2008, we reported that radical prostatectomy, as compared with watchful waiting, reduces the rate of death from prostate cancer. After an additional 3 years of follow-up, we now report estimated 15-year results...
  8. ncbi request reprint Radical prostatectomy versus watchful waiting in early prostate cancer
    Anna Bill-Axelson
    Department of Urology, University Hospital, Uppsala, Sweden
    N Engl J Med 352:1977-84. 2005
    ..In 2002, we reported the initial results of a trial comparing radical prostatectomy with watchful waiting in the management of early prostate cancer. After three more years of follow-up, we report estimated 10-year results...
  9. doi request reprint Long-term quality-of-life outcomes after radical prostatectomy or watchful waiting: the Scandinavian Prostate Cancer Group-4 randomised trial
    Eva Johansson
    Department of Surgical Sciences, University Hospital of Uppsala, Uppsala, Sweden
    Lancet Oncol 12:891-9. 2011
    ..We report results for quality of life for men in the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) after a median follow-up of more than 12 years...
  10. doi request reprint Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation
    Johan Botling
    Departments of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
    Clin Cancer Res 19:194-204. 2013
    ..So far, the value of these multigene signatures in clinical practice is unclear, and the biologic importance of individual genes is difficult to assess, as the published signatures virtually do not overlap...
  11. doi request reprint Social differences in breast cancer survival in relation to patient management within a National Health Care System (Sweden)
    Sonja Eaker
    Department of Surgery, Uppsala University, Uppsala, Sweden
    Int J Cancer 124:180-7. 2009
    ....
  12. pmc Serum levels of selenium and smoking habits at age 50 influence long term prostate cancer risk; a 34 year ULSAM follow-up
    Birgitta Grundmark
    Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
    BMC Cancer 11:431. 2011
    ..We investigated the relation between s-Se, smoking and non-screening detected PrCa and explored if polymorphisms in two DNA repair genes: OGG1 and MnSOD, influenced any effect of s-Se...
  13. doi request reprint Borderline ovarian tumors in Sweden 1960-2005: trends in incidence and age at diagnosis compared to ovarian cancer
    Ingiridur Skirnisdottir
    Department of Women s and Children s Health, Obstetrics and Gynecology, Uppsala University, Uppsala, Sweden
    Int J Cancer 123:1897-901. 2008
    ....
  14. doi request reprint Long-term distress after radical prostatectomy versus watchful waiting in prostate cancer: a longitudinal study from the Scandinavian Prostate Cancer Group-4 randomized clinical trial
    Anna Bill-Axelson
    Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
    Eur Urol 64:920-8. 2013
    ..Yet, overcoming patient selection forces is a formidable challenge for observational studies comparing treatment groups...
  15. ncbi request reprint [Radical prostatectomy reduces the risk of death in prostatic cancer. The effect on total mortality can not be established yet as shown in a randomized controlled trial]
    Anna Bill-Axelson
    Urologiska kliniken, Akademiska sjukhuset, Uppsala
    Lakartidningen 100:1714-6. 2003
  16. doi request reprint Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer
    Patrick Micke
    Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
    J Thorac Oncol 6:1833-40. 2011
    ..To maximize the chance to identify clinically relevant events, we applied a strategy involving two prognostically extreme patient groups...
  17. doi request reprint Season of diagnosis and prognosis in breast and prostate cancer
    Lars Holmberg
    Regional Oncologic Center and Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
    Cancer Causes Control 20:663-70. 2009
    ..Patients with breast or prostate cancer diagnosed during the summer season have been observed to have better survival. The extent to which this is due to biological and/or health care system related factors is unclear...
  18. ncbi request reprint Non-genital tract metastases to the ovaries presented as ovarian tumors in Sweden 1990-2003: occurrence, origin and survival compared to ovarian cancer
    Ingiridur Skirnisdottir
    Department of Women s and Children s Health, Obstetrics and Gynecology, Akademiska University Hospital, Uppsala, Sweden
    Gynecol Oncol 105:166-71. 2007
    ..Origin of metastases and time of detection in relation to surgery were recorded. Age at diagnosis, survival for ovarian metastasis compared to ovarian cancer and prognostic factors were evaluated...
  19. doi request reprint Time, symptom burden, androgen deprivation, and self-assessed quality of life after radical prostatectomy or watchful waiting: the Randomized Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) clinical trial
    Eva Johansson
    Department of Urology, Uppsala University Hospital, Uppsala, Sweden
    Eur Urol 55:422-30. 2009
    ..Quality-of-life outcomes are important in the choice of treatment strategy for men with localized prostate cancer...
  20. doi request reprint Distribution of coronary artery stenosis after radiation for breast cancer
    Greger Nilsson
    Uppsala University, University Hospital, SE 751 85 Uppsala, Sweden
    J Clin Oncol 30:380-6. 2012
    ..To study distribution of coronary artery stenosis among patients with breast cancer (BC) and to assess correlation between radiotherapy (RT) and location of stenosis...
  21. doi request reprint Dietary Patterns and Prostate Cancer Risk: Report from the Population Based ULSAM Cohort Study of Swedish Men
    Erika Ax
    a Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden
    Nutr Cancer 66:77-87. 2014
    ..In this study, a LCHP diet was associated with lower prostate cancer incidence. Relations emerged in adequate reporters, underscoring the importance of high-quality dietary data. ..
  22. ncbi request reprint Regional differences in breast cancer survival despite common guidelines
    Sonja Eaker
    Department of Surgery, Regional Oncologic Centre, University Hospital of Uppsala, SE 751 85 Uppsala, Sweden
    Cancer Epidemiol Biomarkers Prev 14:2914-8. 2005
    ..We therefore examined breast cancer survival in relation to differences in diagnostic activity, tumor characteristics, and treatment in seven Swedish counties within a single health care region...
  23. doi request reprint Increased risk of recurrence after hormone replacement therapy in breast cancer survivors
    Lars Holmberg
    Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
    J Natl Cancer Inst 100:475-82. 2008
    ..We present results after extended follow-up...
  24. doi request reprint Experiences of randomization: interviews with patients and clinicians in the SPCG-IV trial
    Anna Bill-Axelson
    Department of Urology, Uppsala University Hospital, Uppsala, Sweden
    Scand J Urol Nephrol 42:358-63. 2008
    ..This study investigated patients' and clinicians' experiences of randomization with the aim of facilitating trial participation in the future...
  25. pmc The metabolic syndrome and the risk of prostate cancer under competing risks of death from other causes
    Birgitta Grundmark
    Regional Oncologic Centre, Uppsala University Hospital, Uppsala, Sweden
    Cancer Epidemiol Biomarkers Prev 19:2088-96. 2010
    ..Using the National Cholesterol Education Program Adult Treatment panel III (NCEP) and International Diabetes Federation (IDF) definitions of the MetS, we investigated such associations taking competing risks of death into consideration...
  26. ncbi request reprint A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer
    Lars Holmberg
    Regional Oncologic Center, University Hospital, Uppsala, Sweden
    N Engl J Med 347:781-9. 2002
    ..Radical prostatectomy is widely used in the treatment of early prostate cancer. The possible survival benefit of this treatment, however, is unclear. We conducted a randomized trial to address this question...
  27. doi request reprint CD99 is a novel prognostic stromal marker in non-small cell lung cancer
    Karolina Edlund
    Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
    Int J Cancer 131:2264-73. 2012
    ..The results support the concept that stromal properties have an important impact on tumour progression...
  28. pmc Birth outcome in women with previously treated breast cancer--a population-based cohort study from Sweden
    Kristina Dalberg
    Department of Surgery and the Regional Oncologic Centre, Uppsala University Hospital, Uppsala, Sweden
    PLoS Med 3:e336. 2006
    ..The aim of this study was to assess the risk of adverse birth outcomes in women previously treated for invasive breast cancer compared with the general population of mothers...
  29. ncbi request reprint No increased prostate cancer incidence after negative transrectal ultrasound guided multiple biopsies in men with increased prostate specific antigen and/or abnormal digital rectal examination
    Anna Bill-Axelson
    Department of Urology, Uppsala University Hospital, Uppsala, Sweden
    J Urol 170:1180-3. 2003
    ..We investigated the incidence of prostate cancer after negative transrectal ultrasound (TRUS) guided multiple biopsies. Our secondary aim was to calculate the sensitivity of the extended protocol used...
  30. ncbi request reprint Increased incidence of stroke in women with breast cancer
    Greger Nilsson
    Section of Oncology, Department of Oncology, Radiology and Clinical Immunology, University Hospital, SE 751 85 Uppsala, Sweden
    Eur J Cancer 41:423-9. 2005
    ..A statistically significant increase in the risk of stroke was seen among women with a history of breast cancer. Whether this risk is associated with the breast cancer disease per se or related to any treatment requires further study...
  31. doi request reprint Cyclin B is an immunohistochemical proliferation marker which can predict for breast cancer death in low-risk node negative breast cancer
    Anthoula Koliadi
    Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden
    Acta Oncol 49:816-20. 2010
    ..Cyclin B is a proliferative marker easily assessed by immunohistochemistry. We wanted to examine cyclin B as a prognostic factor in low-risk breast cancer patients...
  32. ncbi request reprint Neoadjuvant cisplatin-methotrexate chemotherapy for invasive bladder cancer -- Nordic cystectomy trial 2
    Amir Sherif
    Department of Urology, Akademiska University Hospital, Uppsala, Sweden
    Scand J Urol Nephrol 36:419-25. 2002
    ..The aim of this study was to investigate if solely neoadjuvant chemotherapy could influence survival in patients with advanced urothelial bladder cancer undergoing cystectomy...
  33. pmc Survival endpoints in colorectal cancer and the effect of second primary other cancer on disease free survival
    Helgi Birgisson
    Department of Surgical Sciences, Colorectal Surgery, Uppsala University, Uppsala, Sweden
    BMC Cancer 11:438. 2011
    ..The aim of this study was to compare different survival endpoints in patients with primary colorectal cancer (CRC) and to understand the effect of second primary other cancer on disease-free survival (DFS) calculations...
  34. doi request reprint Regional differences in treatment and outcome in non-small cell lung cancer: a population-based study (Sweden)
    Gunnar Myrdal
    Department of Thoracic and Cardiovascular Surgery, Uppsala University Hospital, Uppsala, Sweden
    Lung Cancer 63:16-22. 2009
    ..Despite common guidelines there were marked differences in treatment activity between the counties. Treatment activity was associated with survival. Survival benefits may follow improvement in compliance to guidelines...
  35. doi request reprint Plasma vitamin D and mortality in older men: a community-based prospective cohort study
    Karl Michaelsson
    Department of Surgical Sciences and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden
    Am J Clin Nutr 92:841-8. 2010
    ..Vitamin D status is known to be important for bone health but may also affect the development of several chronic diseases, including cancer and cardiovascular diseases, which are 2 major causes of death...
  36. ncbi request reprint The role of the primary-care physician in oncology care. Primary healthcare and specialist cancer services
    Lars Holmberg
    Regional Oncologic Centre, Uppsala, Sweden
    Lancet Oncol 6:121-2. 2005
  37. doi request reprint A 9-year follow-up study of participants and nonparticipants in sigmoidoscopy screening: importance of self-selection
    Johannes Blom
    Division of Surgery, Department for Clinical Science, Intervention and Technology, Karolinska Institutet at Karolinska University Hospital, K53, Huddinge, 141 86 Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 17:1163-8. 2008
    ..Self-selection may compromise cost-effectiveness of screening programs. We hypothesized that nonparticipants have generally higher morbidity and mortality than participants...
  38. ncbi request reprint Clinical characteristics and primary treatment of prostate cancer in Sweden between 1996 and 2005
    Jan Adolfsson
    Oncological Centre, Karolinska University Hospital, CLINTEC, Karolinska Institute, Stockholm, Sweden
    Scand J Urol Nephrol 41:456-77. 2007
    ..The incidence of prostate cancer is rising rapidly in Sweden and there is a need to better understand the pattern of diagnosis, tumor characteristics and treatment...
  39. pmc Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts
    Yudi Pawitan
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Breast Cancer Res 7:R953-64. 2005
    ..Breast cancer expression profiling has so far mainly been used to identify women with a poor prognosis as candidates for adjuvant therapy but without demonstrated value for therapy prediction...
  40. ncbi request reprint The National Prostate Cancer Register in Sweden 1998-2002: trends in incidence, treatment and survival
    Eberhard Varenhorst
    Department of Urology, Faculty of Health Sciences, University Hospital Linkoping, Linkoping, Sweden
    Scand J Urol Nephrol 39:117-23. 2005
    ..To provide a descriptive review of the establishment of the National Prostate Cancer Register (NPCR) in Sweden, to present clinical characteristics at diagnosis and to calculate the relative survival of different risk groups after 5 years...
  41. ncbi request reprint Long-term survival of patients with small intestinal carcinoid tumors
    Niklas Zar
    Department of Surgery, Ryhov County Hospital, SE 551 85 Jonkoping, Sweden
    World J Surg 28:1163-8. 2004
    ..The divergence between cause-specific and relative survival implies the need for a more detailed analysis of the causes of death of these patients...
  42. ncbi request reprint [Registries contribute to better breast cancer care]
    Leif Bergkvist
    Kirurgkliniken och Centrum för klinisk forskning, Centrallasarettet, Vasteras
    Lakartidningen 101:2579-81. 2004
  43. ncbi request reprint [Prostatic cancer in Sweden 1998-2003. Drastic change of the disease panorama]
    Eberhard Varenhorst
    Halsouniversitetet i Linkoping
    Lakartidningen 103:285-8. 2006
  44. ncbi request reprint SweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening
    Stefan O Emdin
    Department of Surgery, Umea University Hospital, Umea, Sweden
    Acta Oncol 45:536-43. 2006
    ..Women undergoing sector resection for DCIS under conditions of population based screening mammography benefit from postoperative RT to the breast. Seven patients needed RT-treatment to prevent one recurrence...
  45. pmc Lung cancer incidence in never smokers
    Heather A Wakelee
    Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, USA
    J Clin Oncol 25:472-8. 2007
    ..However, data on this topic, particularly lung cancer incidence rates in never smokers, are limited...
  46. ncbi request reprint Prostate-specific antigen levels as a predictor of lethal prostate cancer
    Katja Fall
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, S 171 77 Stockholm, Sweden
    J Natl Cancer Inst 99:526-32. 2007
    ..Rates of long-term survival among patients with untreated localized prostate cancer are high. To avoid unnecessary treatment, tools are needed to identify the small proportion of patients who are destined to develop lethal prostate cancer...
  47. ncbi request reprint Natural history of early, localized prostate cancer
    Jan Erik Johansson
    Department of Urology, Orebro University Hospital, Orebro, Sweden
    JAMA 291:2713-9. 2004
    ..However, little is known about disease progression and mortality beyond 10 to 15 years of watchful waiting...
  48. ncbi request reprint Neoadjuvant cisplatinum based combination chemotherapy in patients with invasive bladder cancer: a combined analysis of two Nordic studies
    Amir Sherif
    Department of Urology, Akademiska University Hospital, SE 751 85 Uppsala, Sweden
    Eur Urol 45:297-303. 2004
    ..We analyzed overall survival in all patients and in prespecified subgroups defined by preoperative T-stage, gender and age...
  49. ncbi request reprint [Quicker reporting to the Cancer Registry is required, according to a new regulation]
    Lotti Barlow
    Epidemiologiskt centrum, Socialstyrelsen, Stockholm
    Lakartidningen 100:3152-4. 2003
  50. ncbi request reprint Alcohol intake and colorectal cancer: a pooled analysis of 8 cohort studies
    Eunyoung Cho
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Harvard School of Public Health, and Harvard Center for Cancer Prevention, Boston, Massachusetts 02115, USA
    Ann Intern Med 140:603-13. 2004
    ..However, findings related to specific alcoholic beverages or different anatomic sites in the large bowel have been inconsistent...
  51. ncbi request reprint Determinants of cancer patients' utilization of hospital care within two years after diagnosis
    Birgitta B K Johansson
    Department of Oncology, Radiology and Clinical Immunology, the Section of Caring Sciences, Uppsala University, Sweden
    Acta Oncol 43:536-44. 2004
    ..The results suggest that thorough assessment can identify patients at diagnosis with an increased need for follow-up, e.g. intensified home care services...
  52. ncbi request reprint Overexpression of cyclin E protein is associated with specific mutation types in the p53 gene and poor survival in human breast cancer
    Thomas Lindahl
    Department of Oncology and Pathology, Radiumhemmet, Karolinska Hospital and Institute R8 03, S 171 76 Stockholm, Sweden
    Carcinogenesis 25:375-80. 2004
    ..4, 95% confidence interval 1.3-4.5). In summary, our findings demonstrate that overexpression of cyclin E is associated with an aggressive tumor phenotype and specific types of p53 mutations...
  53. ncbi request reprint Dietary calcium and vitamin D intake and risk of colorectal cancer: a prospective cohort study in women
    Paul Terry
    Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
    Nutr Cancer 43:39-46. 2002
    ..Vitamin D intake was not clearly associated with risk. In sum, our data suggest that high calcium intake may lower colorectal cancer risk...
  54. ncbi request reprint Quality of life after radical prostatectomy or watchful waiting
    Gunnar Steineck
    Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden
    N Engl J Med 347:790-6. 2002
    ..We evaluated symptoms and self-assessments of quality of life in men with localized prostate cancer who participated in a randomized comparison between radical prostatectomy and watchful waiting...
  55. ncbi request reprint The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish counties
    Stephen W Duffy
    Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, PO Box 123, Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    Cancer 95:458-69. 2002
    ..e., nonattenders) after the initiation of organized screening...
  56. ncbi request reprint Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish Mammography Cohort
    Susanna C Larsson
    Division of Nutritional Epidemiology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 113:829-34. 2005
    ..04). These findings suggest that high consumption of red meat may substantially increase the risk of distal colon cancer. Future investigations on red meat and colorectal cancer risk should consider cancer subsites separately...
  57. ncbi request reprint Ductal carcinoma in situ of the breast with different histopathological grades and corresponding new breast tumour events: analysis of loss of heterozygosity
    Johanna Smeds
    Department of Oncology Pathology, Radiumhemmet Cancer Centre Karolinska, Karolinska Institute and Hospital, S 171 76 Stockholm, Sweden
    Acta Oncol 44:41-9. 2005
    ..Also observed was a complete heterogeneity of LOH in the primary DCIS and their corresponding new events, suggesting that these events probably developed from genetically divergent clones...
  58. ncbi request reprint The National Penile Cancer Register in Sweden 2000-2003
    Beata Persson
    Departments of Urology, Orebro University Hospital, Orebro, Sweden
    Scand J Urol Nephrol 41:278-82. 2007
    ..The register elicits treatment disparities between regions, and aims to determine the impact of clinical practice guidelines introduced in Sweden...
  59. ncbi request reprint Colorectal cancer survival in the Nordic countries and the United Kingdom: excess mortality risk analysis of 5 year relative period survival in the period 1999 to 2000
    Gerda Engholm
    Department of Cancer Prevention and Documentation, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 121:1115-22. 2007
    ..Use of more detailed age-intervals than conventionally applied in survival studies proved to be important in statistical modelling and is recommended for future studies...
  60. ncbi request reprint Toward understanding nonparticipation in sigmoidoscopy screening for colorectal cancer
    Johannes Blom
    Division of Surgery, Department for Clinical Science, Intervention and Technology, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Int J Cancer 122:1618-23. 2008
    ..To increase compliance, invitations must appeal to men, unmarried or divorced people and people with low socioeconomic status...
  61. doi request reprint Nine-gene molecular signature is not associated with prostate cancer death in a watchful waiting cohort
    Lorelei A Mucci
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:249-51. 2008
    ..We quantified protein expression of the nine genes in tumors to classify progression risk. Accounting for clinical prognostic factors, the nine-gene model did not provide discrimination to predict lethal and indolent prostate cancer...
  62. doi request reprint Risk of second primary malignancies and causes of death in patients with adenocarcinoma and carcinoid of the small intestine
    Niklas Zar
    Department of Surgery, Ryhov County Hospital, Jonkoping, Sweden
    Eur J Cancer 44:718-25. 2008
    ..A detailed analysis of causes of death in a population-based cohort of small intestinal malignancies has not been presented before in the literature...
  63. doi request reprint Absolute risk reductions for local recurrence after postoperative radiotherapy after sector resection for ductal carcinoma in situ of the breast
    Lars Holmberg
    Division of Cancer Studies, Thomas Guy House, 3rd Floor, King s College London, Guy s Campus, London SE1 9RT, United Kingdom
    J Clin Oncol 26:1247-52. 2008
    ..Evaluate the effects of radiotherapy after sector resection for ductal carcinoma in situ of the breast (DCIS) in patient groups as defined by age, size of the lesion, focality, completeness of excision and mode of detection...
  64. doi request reprint Active surveillance for early-stage prostate cancer: review of the current literature
    Marc A Dall'Era
    Department of Urology, University of California at San Francisco Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 1695, USA
    Cancer 112:1650-9. 2008
    ..The best candidates for active surveillance are being defined, as are predictors of active treatment. The psychosocial ramifications of surveillance for prostate cancer can be profound and future needs and unmet goals will be discussed...
  65. pmc Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD)
    Sandra L Haberichter
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA
    Blood 111:4979-85. 2008
    ..The systematic assay of both plasma VWF and the VWF propeptide in moderately severe type 1 VWD patients may identify patients with a reduced VWF survival phenotype...
  66. ncbi request reprint Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD)
    Anne Goodeve
    The Academic Unit of Haematology, University of Sheffield, United Kingdom
    Blood 109:112-21. 2007
    ..About one third of the type 1 VWD cases recruited could be reconsidered as type 2. The remaining group could be considered "true" type 1 VWD, although mutations were found in only 55%...
  67. ncbi request reprint The usefulness of a multidisciplinary educational programme after breast cancer surgery: a prospective and comparative study
    IngaLill Koinberg
    Department of Research 3D, Varberg Hospital, S 432 81 Varberg, Sweden
    Eur J Oncol Nurs 10:273-82. 2006
    ..A multidisciplinary educational programme may be an alternative to traditional follow-up by a physician after breast cancer surgery, but more research is needed about the financial benefits and effectiveness of such a programme...
  68. ncbi request reprint Residual adverse changes in arterial endothelial function and LDL oxidation after a mild systemic inflammation induced by influenza vaccination
    Petru Liuba
    Paediatric Cardiology, Lund University Hospital, Lund, Sweden
    Ann Med 39:392-9. 2007
    ....
  69. ncbi request reprint Breast cancer patients' satisfaction with a spontaneous system of check-up visits to a specialist nurse
    Inga Lill Koinberg
    Oncology Clinic, Varberg Hospital, Varberg, Sweden
    Scand J Caring Sci 16:209-15. 2002
    ..To describe breast cancer patients' satisfaction with a spontaneous system of check-up visits to a specialist nurse...