Hans Henrik Fuxelius

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Visualization of pseudogenes in intracellular bacteria reveals the different tracks to gene destruction
    Hans Henrik Fuxelius
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, S 752 36 Uppsala, Sweden
    Genome Biol 9:R42. 2008
  2. ncbi request reprint Intracellular pathogens go extreme: genome evolution in the Rickettsiales
    Alistair C Darby
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, S 752 36 Uppsala, Sweden
    Trends Genet 23:511-20. 2007
  3. ncbi request reprint The genomic and metabolic diversity of Rickettsia
    Hans Henrik Fuxelius
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, S 752 36 Uppsala, Sweden
    Res Microbiol 158:745-53. 2007
  4. ncbi request reprint The complete genome sequence of Francisella tularensis, the causative agent of tularemia
    Par Larsson
    Swedish Defence Research Agency, SE 901 82 Umea, Sweden
    Nat Genet 37:153-9. 2005
  5. pmc The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes
    Nam Hyuk Cho
    Department of Microbiology and Immunology, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 799, Republic of Korea
    Proc Natl Acad Sci U S A 104:7981-6. 2007

Collaborators

  • Siv Ge Andersson
  • Nam Hyuk Cho
  • B W Wren
  • Peter Karp
  • Richard W Titball
  • Alistair C Darby
  • Par Larsson
  • Joakim Westberg
  • Daniel Johansson
  • Jonathan K Wagg
  • Nick Thompson
  • Karen E Isherwood
  • Luther E Lindler
  • Melanie Duffield
  • Richard Prior
  • Ying Liu
  • Joann Prior
  • Lisa Vergez
  • Eva Larsson
  • Petra C F Oyston
  • Anders Sjostedt
  • Greger Hälltorp
  • May C Chu
  • Mats Forsman
  • Stephanie Malfatti
  • Kerstin Svensson
  • Stephen Michell
  • Emilio Garcia
  • Patrick Chain

Detail Information

Publications5

  1. pmc Visualization of pseudogenes in intracellular bacteria reveals the different tracks to gene destruction
    Hans Henrik Fuxelius
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, S 752 36 Uppsala, Sweden
    Genome Biol 9:R42. 2008
    ..carry substantial fractions of pseudogenes. Until recently, horizontal gene transfers were considered to be rare events in obligate host-associated bacteria...
  2. ncbi request reprint Intracellular pathogens go extreme: genome evolution in the Rickettsiales
    Alistair C Darby
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, S 752 36 Uppsala, Sweden
    Trends Genet 23:511-20. 2007
    ..Here, we explore the genomic differences between members of the Rickettsiales and ask what are the changes that enable infectious agents to emerge from seemingly harmless bacteria...
  3. ncbi request reprint The genomic and metabolic diversity of Rickettsia
    Hans Henrik Fuxelius
    Department of Molecular Evolution, Evolutionary Biology Center, Uppsala University, Norbyvagen 18C, S 752 36 Uppsala, Sweden
    Res Microbiol 158:745-53. 2007
    ..These contradictory evolutionary forces highlight the influence of chance, adaptation and host-cell exploitation during the evolution of intracellular bacteria...
  4. ncbi request reprint The complete genome sequence of Francisella tularensis, the causative agent of tularemia
    Par Larsson
    Swedish Defence Research Agency, SE 901 82 Umea, Sweden
    Nat Genet 37:153-9. 2005
    ..tularensis is an obligate host-dependent bacterium in its natural life cycle. Our results have implications for our understanding of how highly virulent human pathogens evolve and will expedite strategies to combat them...
  5. pmc The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes
    Nam Hyuk Cho
    Department of Microbiology and Immunology, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 799, Republic of Korea
    Proc Natl Acad Sci U S A 104:7981-6. 2007
    ..Diversifying selection on host-cell interaction genes along with repeated population bottlenecks may drive rare genome variants to fixation, thereby short-circuiting selection for low complexity in bacterial genomes...