Anders Fredriksson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Brief alcohol intervention in a psychiatric outpatient setting: a randomized controlled study
    Christina Nehlin
    Department of Neuroscience, Psychiatry, Uppsala University, Uppsala, Sweden
    Addict Sci Clin Pract 7:23. 2012
  2. ncbi request reprint Neurofunctional deficits and potentiated apoptosis by neonatal NMDA antagonist administration
    Anders Fredriksson
    Department of Neuroscience, Psychiatry Ulleraker, Uppsala University, SE 750 17 Uppsala, Sweden
    Behav Brain Res 153:367-76. 2004
  3. ncbi request reprint Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits
    Anders Fredriksson
    Department of Neuroscience, Psychiatry Ulleraker, Uppsala University, Uppsala, Sweden
    Anesthesiology 107:427-36. 2007
  4. ncbi request reprint Coexposure of neonatal mice to a flame retardant PBDE 99 (2,2',4,4',5-pentabromodiphenyl ether) and methyl mercury enhances developmental neurotoxic defects
    Celia Fischer
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36 Uppsala, Sweden
    Toxicol Sci 101:275-85. 2008
  5. ncbi request reprint Functional consequences of iron overload in catecholaminergic interactions: the Youdim factor
    Trevor Archer
    Department of Neuroscience and Psychiatry, Ulleraker, University of Uppsala, Uppsala, 750 17, Sweden
    Neurochem Res 32:1625-39. 2007
  6. doi request reprint Neonatal ketamine exposure results in changes in biochemical substrates of neuronal growth and synaptogenesis, and alters adult behavior irreversibly
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Uppsala, Sweden
    Toxicology 249:153-9. 2008
  7. ncbi request reprint Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 75236 Uppsala, Sweden
    Toxicol Appl Pharmacol 192:95-106. 2003
  8. doi request reprint Neonatal exposure to propofol affects BDNF but not CaMKII, GAP-43, synaptophysin and tau in the neonatal brain and causes an altered behavioural response to diazepam in the adult mouse brain
    Emma Pontén
    Department of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Sweden
    Behav Brain Res 223:75-80. 2011
  9. ncbi request reprint Changes in spontaneous behaviour and altered response to nicotine in the adult rat, after neonatal exposure to the brominated flame retardant, decabrominated diphenyl ether (PBDE 209)
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE 75236 Uppsala, Sweden
    Neurotoxicology 28:136-42. 2007
  10. ncbi request reprint Polybrominated diphenyl ethers, a group of brominated flame retardants, can interact with polychlorinated biphenyls in enhancing developmental neurobehavioral defects
    Per Eriksson
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36 Uppsala, Sweden
    Toxicol Sci 94:302-9. 2006

Detail Information

Publications33

  1. pmc Brief alcohol intervention in a psychiatric outpatient setting: a randomized controlled study
    Christina Nehlin
    Department of Neuroscience, Psychiatry, Uppsala University, Uppsala, Sweden
    Addict Sci Clin Pract 7:23. 2012
    ..By using clinical psychiatric staff to perform the interventions, we sought to collect information of the usefulness of BI in the clinical setting...
  2. ncbi request reprint Neurofunctional deficits and potentiated apoptosis by neonatal NMDA antagonist administration
    Anders Fredriksson
    Department of Neuroscience, Psychiatry Ulleraker, Uppsala University, SE 750 17 Uppsala, Sweden
    Behav Brain Res 153:367-76. 2004
    ..The potentiated apoptosis induced by ketamine and diazepam may have implications for the selection of drugs used in neonatal paediatric anaesthesia...
  3. ncbi request reprint Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits
    Anders Fredriksson
    Department of Neuroscience, Psychiatry Ulleraker, Uppsala University, Uppsala, Sweden
    Anesthesiology 107:427-36. 2007
    ..This study examined whether different anesthetic agents, alone and in combination, administered to neonate mice, can trigger apoptosis and whether behavioral deficits occur later in adulthood...
  4. ncbi request reprint Coexposure of neonatal mice to a flame retardant PBDE 99 (2,2',4,4',5-pentabromodiphenyl ether) and methyl mercury enhances developmental neurotoxic defects
    Celia Fischer
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36 Uppsala, Sweden
    Toxicol Sci 101:275-85. 2008
    ..This is of vital importance, as the levels of PBDEs are increasing in mother's milk and in the environment generally...
  5. ncbi request reprint Functional consequences of iron overload in catecholaminergic interactions: the Youdim factor
    Trevor Archer
    Department of Neuroscience and Psychiatry, Ulleraker, University of Uppsala, Uppsala, 750 17, Sweden
    Neurochem Res 32:1625-39. 2007
    ..These findings suggest an essential neonatal iron overload, termed "the Youdim factor", directing a DA-NA interactive component in co-morbid disorders of nigrostriatal-limbic brain regions...
  6. doi request reprint Neonatal ketamine exposure results in changes in biochemical substrates of neuronal growth and synaptogenesis, and alters adult behavior irreversibly
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Uppsala, Sweden
    Toxicology 249:153-9. 2008
    ....
  7. ncbi request reprint Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 75236 Uppsala, Sweden
    Toxicol Appl Pharmacol 192:95-106. 2003
    ..The observed developmental neurotoxic effects seen for PBDE 153 are similar to those seen for PBDE 99 and for certain PCBs. Furthermore, PBDEs appear to as potent as the PCBs...
  8. doi request reprint Neonatal exposure to propofol affects BDNF but not CaMKII, GAP-43, synaptophysin and tau in the neonatal brain and causes an altered behavioural response to diazepam in the adult mouse brain
    Emma Pontén
    Department of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Sweden
    Behav Brain Res 223:75-80. 2011
    ..These changes may be due to neonatal alterations in BDNF levels...
  9. ncbi request reprint Changes in spontaneous behaviour and altered response to nicotine in the adult rat, after neonatal exposure to the brominated flame retardant, decabrominated diphenyl ether (PBDE 209)
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE 75236 Uppsala, Sweden
    Neurotoxicology 28:136-42. 2007
    ..It is also clear from the present study and from recent studies from our research group that both lower and higher brominated diphenyl ethers can cause similar developmental neurotoxic effects in both mice and rats...
  10. ncbi request reprint Polybrominated diphenyl ethers, a group of brominated flame retardants, can interact with polychlorinated biphenyls in enhancing developmental neurobehavioral defects
    Per Eriksson
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36 Uppsala, Sweden
    Toxicol Sci 94:302-9. 2006
    ..The neurobehavioral defects were also seen to worsen with age in mice neonatally exposed to PCB 52 + PBDE 99...
  11. ncbi request reprint 2,6-dichlorophenyl methylsulphone induced behavioural impairments in rats and mice in relation to olfactory mucosal metaplasia
    Carina Carlsson
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE 752 36, Sweden
    Pharmacol Toxicol 93:156-68. 2003
    ..We propose that the observed hyperactivity and radial arm maze acquisition deficits originated from a direct effect of 2,6-diClPh-MeSO2 in the brain rather than being a consequence of the olfactory mucosal lesion...
  12. ncbi request reprint Neurobehavioral derangements in adult mice receiving decabrominated diphenyl ether (PBDE 209) during a defined period of neonatal brain development
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvägen, Uppsala, Sweden
    Toxicol Sci 76:112-20. 2003
    ..We conclude that more attention should be focused on the highly brominated PBDEs as possible developmental neurotoxic agents...
  13. ncbi request reprint Investigations of strain and/or gender differences in developmental neurotoxic effects of polybrominated diphenyl ethers in mice
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 75236 Uppsala, Sweden
    Toxicol Sci 81:344-53. 2004
    ..Furthermore, the effects of PBDEs appear to be as potent in female mice as in male mice, and as potent in C57/Bl mice as in NMRI mice, concerning developmental neurotoxicity...
  14. ncbi request reprint Increased susceptibility to adult paraoxon exposure in mice neonatally exposed to nicotine
    Emma Ankarberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE 752 36, Uppsala, Sweden
    Toxicol Sci 82:555-61. 2004
    ..Animals neonatally exposed to nicotine and exposed to paraoxon as adults showed a deranged spontaneous motor behavior, including hyperactivity and lack of habituation...
  15. pmc VGLUT2 in dopamine neurons is required for psychostimulant-induced behavioral activation
    Carolina Birgner
    Unit of Developmental Genetics, Department of Neuroscience, Uppsala University, S 751 24 Uppsala, Sweden
    Proc Natl Acad Sci U S A 107:389-94. 2010
    ..Our results show that VGLUT2 expression in DA neurons is required for normal emotional reactivity as well as for psychostimulant-mediated behavioral activation...
  16. ncbi request reprint Neonatal co-exposure to low doses of an ortho-PCB (PCB 153) and methyl mercury exacerbate defective developmental neurobehavior in mice
    Celia Fischer
    Department of Environmental Toxicology, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18A, S 752 36 Uppsala, Sweden
    Toxicology 244:157-65. 2008
    ..These effects are manifested as disrupted spontaneous behavior, lack of habituation, and reduced cognitive functions. These effects occur at doses within the same order of magnitude as reported for exposed children...
  17. doi request reprint Interaction of gamma-radiation and methyl mercury during a critical phase of neonatal brain development in mice exacerbates developmental neurobehavioural effects
    Per Eriksson
    Department of Environmental Toxicology, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18A, Uppsala, Sweden
    Neurotoxicology 31:223-9. 2010
    ..The study shows that gamma-radiation and MeHg can interact and significantly exacerbate developmental neurotoxic effects, as manifested by disrupted spontaneous behaviour, lack of habituation, and impaired learning and memory functions...
  18. doi request reprint Dose-dependent behavioral disturbances after a single neonatal Bisphenol A dose
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE 75236 Uppsala, Sweden
    Toxicology 290:187-94. 2011
    ..The present findings show similarities with effects earlier reported after pre- and perinatal exposure to Bisphenol A, and also with effects seen after a single postnatal exposure to other POPs, such as PBDEs, PCBs and PFCs...
  19. ncbi request reprint Neonatal exposure to higher brominated diphenyl ethers, hepta-, octa-, or nonabromodiphenyl ether, impairs spontaneous behavior and learning and memory functions of adult mice
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, S 752 36 Uppsala, Sweden
    Toxicol Sci 92:211-8. 2006
    ..It is important to consider the fact that different PBDE congeners can have differing degrees of potency, when comparing levels of PBDEs in the environment and in mother's milk...
  20. ncbi request reprint Brain lipid composition in postnatal iron-induced motor behavior alterations following chronic neuroleptic administration in mice
    Giorgis Isaac
    Department of Analytical Chemistry, Biomedical Center, Uppsala University, Sweden
    FEBS J 273:2232-43. 2006
    ..In conclusion our results support the hypothesis that an association between psychiatric disorders and lipid and behavior abnormalities in the brain exists...
  21. doi request reprint Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function
    Asa Wallen-Mackenzie
    Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden
    J Neurosci 29:2238-51. 2009
    ..The present study provides support for the existence of a neurocircuitry that connects changes in VGLUT2-mediated neurotransmission to alterations in the dopaminergic system with schizophrenia-like behavioral deficits as a major outcome...
  22. ncbi request reprint Effect of postnatal iron administration on MPTP-induced behavioral deficits and neurotoxicity: behavioral enhancement by L-Dopa-MK-801 co-administration
    Anders Fredriksson
    Department of Neuroscience and Psychiatry, University of Uppsala, Ulleraker, SE 750 17, Uppsala, Sweden
    Behav Brain Res 139:31-46. 2003
    ....
  23. ncbi request reprint Behavioural changes related to olfactory mucosal metaplasia and bulbar glial fibrillary acidic protein (GFAP) induction in methylsulphonyl-dichlorobenzene-treated mice
    Carina Carlsson
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, 752 36, Uppsala, Sweden
    Arch Toxicol 76:474-83. 2002
    ..A targeted uptake of metabolites into the olfactory bulb could also contribute to the GFAP induction and/or behaviour response...
  24. doi request reprint Running wheel activity restores MPTP-induced functional deficits
    Anders Fredriksson
    Department of Neuroscience Psychiatry, Uppsala University, 751 85, Uppsala, Sweden
    J Neural Transm 118:407-20. 2011
    ..BDNF protein level in the parietal cortex was elevated by the MPTP insult and increased further by physical exercise. Physical running wheel exercise alleviated both the functional and biomarker expressions of MPTP-induced parkinsonism...
  25. doi request reprint A randomized controlled trial of the illness management and recovery program for persons with schizophrenia
    Rickard Färdig
    Department of Neuroscience Psychiatry, Uppsala University Hospital, Ing 15, SE 75185 Uppsala, Sweden
    Psychiatr Serv 62:606-12. 2011
    ..The aim of the study was to evaluate the effects of the illness management and recovery (IMR) program on symptoms and psychosocial functioning of individuals with schizophrenia or schizoaffective disorder in an outpatient setting in Sweden...
  26. ncbi request reprint Neonatal exposure to the brominated flame retardant 2,2',4,4',5-pentabromodiphenyl ether causes altered susceptibility in the cholinergic transmitter system in the adult mouse
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE 75236 Uppsala, Sweden
    Toxicol Sci 67:104-7. 2002
    ..This indicates that PBDE 99 can affect the cholinergic system and might thereby interact with other environmental toxicants...
  27. doi request reprint Neonatal exposure to sucralose does not alter biochemical markers of neuronal development or adult behavior
    Henrik Viberg
    Department of Environmental Toxicology, Uppsala University, Sweden
    Nutrition 27:81-5. 2011
    ..The proteins calcium/calmodulin-dependent protein kinase II, growth-associated protein-43, synaptophysin, and tau play important roles during brain growth and development...
  28. ncbi request reprint Effects of acute administration of DA agonists on locomotor activity: MPTP versus neonatal intracerebroventricular 6-OHDA treatment
    Trevor Archer
    Department of Psychology, P O Box 500, University of Goteborg, Göteborg SE 405 30, Sweden
    Neurotox Res 5:95-110. 2003
    ....
  29. ncbi request reprint Behavioural supersensitivity following neonatal 6-hydroxydopamine: attenuation by MK-801
    T Archer
    Department of Psychology, University of Goteborg, Sweden
    Neurotox Res 12:113-24. 2007
    ..The present findings confirm the influence of non-competitive glutamate antagonists in attenuating the behavioural supersensitivity to dopamine antagonists...
  30. ncbi request reprint Hyperactivity following postnatal NMDA antagonist treatment: reversal by D-amphetamine
    Anders Fredriksson
    University of Uppsala, Department of Neuroscience and Psychiatry, Ulleraker, SE 750 17 Uppsala, Sweden
    Neurotox Res 5:549-64. 2003
    ....
  31. ncbi request reprint Neurobehavioural deficits associated with apoptotic neurodegeneration and vulnerability for ADHD
    Anders Fredriksson
    Department of Neuroscience and Psychiatry, University of Uppsala, Ulleraker, SE 750 17 Uppsala, Sweden
    Neurotox Res 6:435-56. 2004
    ....
  32. ncbi request reprint Dose-response modeling and benchmark calculations from spontaneous behavior data on mice neonatally exposed to 2,2',4,4',5-pentabromodiphenyl ether
    Salomon Sand
    Institute of Environmental Medicine, Karolinska Institutet, P O Box 210, 17177 Stockholm, Sweden
    Toxicol Sci 81:491-501. 2004
    ..Using this methodology, the BMD was defined as corresponding to an excess risk of 5 or 10% of falling below cutoff points representing adverse levels of fractional response...
  33. ncbi request reprint Subchronic administration of haloperidol influences the functional deficits of postnatal iron administration in mice
    Anders Fredriksson
    University of Uppsala, Department of Neuroscience and Psychiatry, Ulleraker, SE 750 17 Uppsala, Sweden
    Neurotox Res 9:305-12. 2006
    ..In the context of these and other observations, it is suggested that subchronic administration of haloperidol interacting with postnatal iron induces different expressions of dopamine neuron comorbidity underlying movement disorder...