Kai M Eggers

Summary

Affiliation: Uppsala University Hospital
Country: Sweden

Publications

  1. ncbi Associations of mid-regional pro-adrenomedullin levels to cardiovascular and metabolic abnormalities, and mortality in an elderly population from the community
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Sweden Electronic address
    Int J Cardiol 168:3537-42. 2013
  2. ncbi Clinical and prognostic implications of circulating pentraxin 3 levels in non ST-elevation acute coronary syndrome
    Kai M Eggers
    Dept of Medical Sciences, Cardiology, Uppsala University, 75237 Uppsala, Sweden Electronic address
    Clin Biochem 46:1655-9. 2013
  3. doi High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden Electronic address
    Am Heart J 166:541-8. 2013
  4. doi Change in growth differentiation factor 15 concentrations over time independently predicts mortality in community-dwelling elderly individuals
    Kai M Eggers
    Department of Medical Sciences and Uppsala Clinical Research Center, Uppsala University, Sweden
    Clin Chem 59:1091-8. 2013
  5. doi Factors influencing the 99th percentile of cardiac troponin I evaluated in community-dwelling individuals at 70 and 75 years of age
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, S 751 85 Uppsala, Sweden
    Clin Chem 59:1068-73. 2013
  6. doi A novel approach to cardiac troponins to improve the diagnostic work-up in chest pain patients
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Crit Pathw Cardiol 11:199-205. 2012
  7. doi Cardiac troponin I levels measured with a high-sensitive assay increase over time and are strong predictors of mortality in an elderly population
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    J Am Coll Cardiol 61:1906-13. 2013
  8. doi Mid-regional pro-atrial natriuretic peptide levels in the elderly: clinical and prognostic implications, and comparison to B-type natriuretic peptides
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Clin Chim Acta 419:62-6. 2013
  9. doi Prognostic usefulness of the change in N-terminal pro B-type natriuretic peptide levels to predict mortality in a single community cohort aged ≥ 70 years
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Am J Cardiol 111:131-6. 2013
  10. doi High-sensitive cardiac troponin T outperforms novel diagnostic biomarkers in patients with acute chest pain
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Clin Chim Acta 413:1135-40. 2012

Detail Information

Publications34

  1. ncbi Associations of mid-regional pro-adrenomedullin levels to cardiovascular and metabolic abnormalities, and mortality in an elderly population from the community
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Sweden Electronic address
    Int J Cardiol 168:3537-42. 2013
    ..We investigated MR-proADM levels and their changes over 5 years in elderly community-dwellers, together with the underlying cardiovascular and metabolic conditions, and the prognostic implications of these measurements...
  2. ncbi Clinical and prognostic implications of circulating pentraxin 3 levels in non ST-elevation acute coronary syndrome
    Kai M Eggers
    Dept of Medical Sciences, Cardiology, Uppsala University, 75237 Uppsala, Sweden Electronic address
    Clin Biochem 46:1655-9. 2013
    ..The aim of the present analysis was to investigate the implications of PTX3 levels in a fairly large sample of NSTE-ACS patients and in comparison to levels of C-reactive protein (CRP)...
  3. doi High-sensitive cardiac troponin T and its relations to cardiovascular risk factors, morbidity, and mortality in elderly men
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden Electronic address
    Am Heart J 166:541-8. 2013
    ..Cardiac troponin is emerging as risk indicator in community-dwelling populations. In this study, we investigated the associations of cardiac troponin T (cTnT) to cardiovascular (CV) disease and outcome in elderly men...
  4. doi Change in growth differentiation factor 15 concentrations over time independently predicts mortality in community-dwelling elderly individuals
    Kai M Eggers
    Department of Medical Sciences and Uppsala Clinical Research Center, Uppsala University, Sweden
    Clin Chem 59:1091-8. 2013
    ..We investigated GDF-15 concentrations and their changes over 5 years in elderly individuals from the community, together with the underlying conditions and prognostic implications of these measurements...
  5. doi Factors influencing the 99th percentile of cardiac troponin I evaluated in community-dwelling individuals at 70 and 75 years of age
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, S 751 85 Uppsala, Sweden
    Clin Chem 59:1068-73. 2013
    ..We aimed to investigate the effects of sex, prevalent cardiovascular disease (CVD), and aging on the 99th percentile of cardiac troponin I (cTnI)...
  6. doi A novel approach to cardiac troponins to improve the diagnostic work-up in chest pain patients
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Crit Pathw Cardiol 11:199-205. 2012
    ..This could facilitate the early diagnostic work-up of chest pain patients, thereby improving patient flow and reducing overcrowding in healthcare facilities...
  7. doi Cardiac troponin I levels measured with a high-sensitive assay increase over time and are strong predictors of mortality in an elderly population
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    J Am Coll Cardiol 61:1906-13. 2013
    ..This study sought to assess changes in troponin levels, underlying conditions, and the prognostic implications in elderly subjects from the community...
  8. doi Mid-regional pro-atrial natriuretic peptide levels in the elderly: clinical and prognostic implications, and comparison to B-type natriuretic peptides
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Clin Chim Acta 419:62-6. 2013
    ..However, there are only sparse data on its clinical value relative to the B-type natriuretic peptides in the general population...
  9. doi Prognostic usefulness of the change in N-terminal pro B-type natriuretic peptide levels to predict mortality in a single community cohort aged ≥ 70 years
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Am J Cardiol 111:131-6. 2013
    ....
  10. doi High-sensitive cardiac troponin T outperforms novel diagnostic biomarkers in patients with acute chest pain
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Clin Chim Acta 413:1135-40. 2012
    ..However, the information obtained from hs-cTnT levels might be improved when combined with results of other biomarkers of myocardial injury...
  11. doi Relations of growth-differentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects
    Kai M Eggers
    Department of Medical Sciences Cardiology and Clinical Chemistry and Clinical Research Center, Uppsala University, Uppsala, Sweden
    Scand J Clin Lab Invest 72:45-51. 2012
    ..GDF-15 is commonly related to cardiovascular risk factors, inflammatory activity and cardiac abnormalities. However, it is not clear whether it might be an indicator of vascular pathologies as well...
  12. doi Utility of B-type natriuretic peptides and cardiac troponins for population screening regarding cardiac abnormalities
    Kai M Eggers
    Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Pathology 44:129-38. 2012
    ..This review focuses on the utility of the B-type natriuretic peptides (NP) and the cardiac troponins (cTns) for this purpose...
  13. doi High-sensitive troponin T and I are related to invasive hemodynamic data and mortality in patients with left-ventricular dysfunction and precapillary pulmonary hypertension
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
    Clin Chim Acta 412:1582-8. 2011
    ....
  14. doi Improving long-term risk prediction in patients with acute chest pain: the Global Registry of Acute Coronary Events (GRACE) risk score is enhanced by selected nonnecrosis biomarkers
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Center, Uppsala, Sweden
    Am Heart J 160:88-94. 2010
    ..However, there is limited knowledge regarding the utility of this score for long-term risk prediction in unselected patients with acute chest pain and whether it might be improved by the integration of nonnecrosis biomarkers...
  15. doi ST2 and mortality in non-ST-segment elevation acute coronary syndrome
    Kai M Eggers
    Department of Medical Sciences, Uppsala University, Sweden
    Am Heart J 159:788-94. 2010
    ....
  16. doi Growth-differentiation factor-15 for long-term risk prediction in patients stabilized after an episode of non-ST-segment-elevation acute coronary syndrome
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Center, Uppsala, Sweden
    Circ Cardiovasc Genet 3:88-96. 2010
    ..This study assessed the time course and the long-term prognostic relevance of GDF-15 levels measured repetitively in patients with non-ST-segment-elevation acute coronary syndrome during 6 months after the acute event...
  17. doi Myeloperoxidase is not useful for the early assessment of patients with chest pain
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Center, Uppsala, Sweden
    Clin Biochem 43:240-5. 2010
    ..Myeloperoxidase (MPO) has been listed as a potentially useful risk marker in acute coronary syndrome. However, its clinical utility in patients with acute chest pain is not yet defined...
  18. doi Prognostic value of biomarkers during and after non-ST-segment elevation acute coronary syndrome
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Centre, Uppsala, Sweden
    J Am Coll Cardiol 54:357-64. 2009
    ..The aim of this study was to assess risk prediction by different biomarkers in patients with an ongoing non-ST-segment elevation acute coronary syndrome (NSTE-ACS) and after clinical stabilization...
  19. doi B-type natriuretic peptides and their relation to cardiovascular structure and function in a population-based sample of subjects aged 70 years
    Kai M Eggers
    Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala, Sweden
    Am J Cardiol 103:1032-8. 2009
    ....
  20. doi Will the universal definition of myocardial infarction criteria result in an overdiagnosis of myocardial infarction?
    Kai M Eggers
    Department of Medical Sciences, Uppsala University Hospital, Sweden
    Am J Cardiol 103:588-91. 2009
    ..In conclusion, our results emphasized the importance of a significant change in cardiac troponin to avoid misdiagnosis of AMI...
  21. doi Value of cardiac troponin I cutoff concentrations below the 99th percentile for clinical decision-making
    Kai M Eggers
    Department of Medical Sciences, Uppsala University Hospital, Sweden
    Clin Chem 55:85-92. 2009
    ....
  22. doi Prevalence and pathophysiological mechanisms of elevated cardiac troponin I levels in a population-based sample of elderly subjects
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital, S 751 85 Uppsala, Sweden
    Eur Heart J 29:2252-8. 2008
    ....
  23. pmc Growth-differentiation factor-15 for early risk stratification in patients with acute chest pain
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital, Uppsala, Sweden
    Eur Heart J 29:2327-35. 2008
    ..We explored the usefulness of GDF-15 for early risk stratification in 479 unselected patients with acute chest pain...
  24. ncbi Risk prediction in chest pain patients by biochemical markers including estimates of renal function
    Kai M Eggers
    Department of Medical Sciences, Cardiology, University Hospital Uppsala, S 751 85 Uppsala, Sweden
    Int J Cardiol 128:207-13. 2008
    ..Early risk stratification of patients with chest pain may be improved by combining cardiac Troponin I (cTnI) results and ECG findings with markers of left-ventricular dysfunction, inflammation or renal function...
  25. doi Pathophysiologic mechanisms of persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital, Uppsala, Sweden
    Am Heart J 156:588-94. 2008
    ..We now have studied the associations of persistently elevated cTnI levels to cardiac performance, inflammation, coagulation, coronary status, and treatment strategy in these patients...
  26. doi Unrecognized myocardial scars detected by delayed-enhanced MRI are associated with increased levels of NT-proBNP
    Raquel Espregueira Themudo
    Department of ORKI, Section of Radiology, Uppsala University Hospital, Sweden
    Coron Artery Dis 22:158-64. 2011
    ..The second aim was to compare whether the TnI levels differed in those two groups...
  27. ncbi Artificial neural network algorithms for early diagnosis of acute myocardial infarction and prediction of infarct size in chest pain patients
    Kai M Eggers
    Department of Medical Sciences, Cardiology, University Hospital Uppsala, S 751 85 Uppsala, Sweden
    Int J Cardiol 114:366-74. 2007
    ..To prospectively validate artificial neural network (ANN)-algorithms for early diagnosis of myocardial infarction (AMI) and prediction of 'major infarct' size in patients with chest pain and without ECG changes diagnostic for AMI...
  28. doi Clinical implications of the change of cardiac troponin I levels in patients with acute chest pain - an evaluation with respect to the Universal Definition of Myocardial Infarction
    Kai M Eggers
    Department of Medical Sciences, Cardiology, Uppsala University Hospital, Sweden
    Clin Chim Acta 412:91-7. 2011
    ..We sought to evaluate the clinical implications of the relative change of cardiac troponin I (cTnI) levels with respect to the Universal Definition in patients with acute chest pain...
  29. ncbi Persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome predicts long-term mortality
    Kai M Eggers
    Department of Medical Sciences, Cardiology, University Hospital Uppsala, S 751 85 Uppsala, Sweden
    Circulation 116:1907-14. 2007
    ..However, the prevalence and prognostic importance of persistent troponin elevation in stabilized patients after an episode of non-ST-elevation acute coronary syndrome are unknown and were therefore assessed in this study...
  30. ncbi Combining different biochemical markers of myocardial ischemia does not improve risk stratification in chest pain patients compared to troponin I alone
    Kai M Eggers
    Department of Cardiology, University Hospital, Uppsala, Sweden
    Coron Artery Dis 16:315-9. 2005
    ..A multimarker strategy applying results of early measurements of different biochemical markers of cardiac necrosis in combination may improve risk prediction in chest pain patients...
  31. pmc GDF-15 for prognostication of cardiovascular and cancer morbidity and mortality in men
    Lars Wallentin
    Uppsala Clinical Research Center UCR and Department of Medical Sciences, Uppsala University, Uppsala, Sweden
    PLoS ONE 8:e78797. 2013
    ..001). In conclusion, in elderly men, GDF-15 improves prognostication of both cardiovascular, cancer mortality and morbidity beyond established risk factors and biomarkers of cardiac, renal dysfunction and inflammation. ..
  32. ncbi Risk prediction in patients with chest pain: early assessment by the combination of troponin I results and electrocardiographic findings
    Kai M Eggers
    Department of Cardiology, University Hospital, Uppsala, Sweden
    Coron Artery Dis 16:181-9. 2005
    ..To evaluate the prognostic value of point of care troponin I (TnI) results in combination with findings from the admission electrocardiogram (ECG) in patients with chest pain...
  33. doi Autoantibodies to cardiac troponin in acute coronary syndromes
    Bertil Lindahl
    Department of Medical Sciences and Uppsala Clinical Research Center, University of Uppsala, Sweden
    Clin Chim Acta 411:1793-8. 2010
    ..However, the prognostic importance of the occurrence of cTnaAb is unknown...
  34. ncbi Prognostic implications of changes in cardiac troponin I levels in patients with non-ST elevation acute coronary syndrome
    Kai M Eggers
    Cardiology Unit, Department of Medical Sciences, Faculty of Medicine, Uppsala University, Uppsala, Sweden and
    Biomarkers 18:668-72. 2013
    ..Information is limited on the prognostic implications of cardiac troponin I (cTnI) changes during the first days of non-ST elevation acute coronary syndrome (NSTE-ACS)...