Mattias Carlström

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. ncbi Role of NOX2 in the regulation of afferent arteriole responsiveness
    Mattias Carlström
    Dept of Medical Cell Biology, Biomedical Centre, Box 571, SE 75123 Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 296:R72-9. 2009
  2. ncbi Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala S 75123, Sweden
    Cardiovasc Res 89:574-85. 2011
  3. ncbi Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Renal Physiol 294:F362-70. 2008
  4. ncbi Causal link between neonatal hydronephrosis and later development of hypertension
    Mattias Carlström
    Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden
    Clin Exp Pharmacol Physiol 37:e14-23. 2010
  5. ncbi Nitric oxide deficiency and increased adenosine response of afferent arterioles in hydronephrotic mice with hypertension
    Mattias Carlström
    Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden
    Hypertension 51:1386-92. 2008
  6. ncbi Angiogenesis inhibition causes hypertension and placental dysfunction in a rat model of preeclampsia
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    J Hypertens 27:829-37. 2009
  7. ncbi SOD1 deficiency causes salt sensitivity and aggravates hypertension in hydronephrosis
    Mattias Carlström
    Dept of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 297:R82-92. 2009
  8. ncbi Superoxide dismutase 1 limits renal microvascular remodeling and attenuates arteriole and blood pressure responses to angiotensin II via modulation of nitric oxide bioavailability
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Hypertension 56:907-13. 2010
  9. ncbi Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment
    Xiang Gao
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 301:R1669-81. 2011
  10. ncbi Neuronal nitric oxide synthase-deficient mice have impaired renin release but normal blood pressure
    Johan Sällström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Hypertens 21:111-6. 2008

Detail Information

Publications14

  1. ncbi Role of NOX2 in the regulation of afferent arteriole responsiveness
    Mattias Carlström
    Dept of Medical Cell Biology, Biomedical Centre, Box 571, SE 75123 Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 296:R72-9. 2009
    ..NOX2 can be activated by elevated ANG II and may play an important role in ANG II-induced hypertension. NOX2-derived ROS scavenges nitric oxide, causing subsequent nitric oxide-deficiency...
  2. ncbi Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala S 75123, Sweden
    Cardiovasc Res 89:574-85. 2011
    ..We tested the hypothesis that dietary inorganic nitrate supplementation may have therapeutic effects in a model of renal and cardiovascular disease...
  3. ncbi Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Renal Physiol 294:F362-70. 2008
    ..Reduced NO availability in the diseased kidney in hydronephrosis, and subsequent resetting of the TGF mechanism, plays an important role in the development of hypertension...
  4. ncbi Causal link between neonatal hydronephrosis and later development of hypertension
    Mattias Carlström
    Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden
    Clin Exp Pharmacol Physiol 37:e14-23. 2010
    ..4. In view of the new knowledge regarding the long-term effects of partial ureteral obstruction, today's non-operative management of hydronephrosis should be reconsidered to prevent obstructive nephropathy and hypertension in later life...
  5. ncbi Nitric oxide deficiency and increased adenosine response of afferent arterioles in hydronephrotic mice with hypertension
    Mattias Carlström
    Department of Medical Cell Biology, Division of Integrative Physiology, Uppsala University, Uppsala, Sweden
    Hypertension 51:1386-92. 2008
    ....
  6. ncbi Angiogenesis inhibition causes hypertension and placental dysfunction in a rat model of preeclampsia
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    J Hypertens 27:829-37. 2009
    ..Preeclampsia is a serious pregnancy complication, accompanied by increased maternal and fetal morbidity. Different models have been used to study preeclampsia, but none of these display all the key features of the disease...
  7. ncbi SOD1 deficiency causes salt sensitivity and aggravates hypertension in hydronephrosis
    Mattias Carlström
    Dept of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 297:R82-92. 2009
    ..Increased superoxide formation may enhance TGF response and thereby contribute to hypertension...
  8. ncbi Superoxide dismutase 1 limits renal microvascular remodeling and attenuates arteriole and blood pressure responses to angiotensin II via modulation of nitric oxide bioavailability
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Hypertension 56:907-13. 2010
    ..This may prevent an early and exaggerated blood pressure response to angiotensin II...
  9. ncbi Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment
    Xiang Gao
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 301:R1669-81. 2011
    ..Interruption of A(1)-receptor signaling blunts l-NAME and ANG II-induced hypertension and oxidative stress and is linked to reduced responsiveness of afferent arterioles...
  10. ncbi Neuronal nitric oxide synthase-deficient mice have impaired renin release but normal blood pressure
    Johan Sällström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Am J Hypertens 21:111-6. 2008
    ..This study was conducted to further elucidate the role of neuronal nitric oxide synthase (nNOS) in blood pressure regulation and renin release in relation to different sodium loads...
  11. ncbi High-protein-induced glomerular hyperfiltration is independent of the tubuloglomerular feedback mechanism and nitric oxide synthases
    Johan Sällström
    Dept of Medical Cell Biology, Uppsala Univ, Biomedical Center, Box 571, SE 751 23 Uppsala, Sweden
    Am J Physiol Regul Integr Comp Physiol 299:R1263-8. 2010
    ..All mice developed high protein-induced hyperfiltration to a similar degree. These results demonstrate that high protein-induced glomerular hyperfiltration is independent of the TGF mechanism and NOS isoforms...
  12. ncbi Hydronephrosis causes salt-sensitive hypertension in rats
    Mattias Carlström
    Department of Medical Cell Biology, Division of Integrative Physiology, University of Uppsala, Uppsala, Sweden
    J Hypertens 24:1437-43. 2006
    ..Hypertension is a common disease in the Western world and approximately 5% of all cases are secondary to kidney malfunction. It is not clear whether unilateral hydronephrosis due to partial obstruction affects blood pressure...
  13. ncbi Uninephrectomy in young age or chronic salt loading causes salt-sensitive hypertension in adult rats
    Mattias Carlström
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Hypertension 49:1342-50. 2007
    ..In conclusion, at a young age after completed nephrogenesis, uninephrectomy or chronic salt loading causes renal and cardiovascular injury with salt-sensitive hypertension...
  14. ncbi Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash
    Joel Petersson
    Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
    Free Radic Biol Med 46:1068-75. 2009
    ..These results suggest that oral symbiotic bacteria modulate gastrointestinal and cardiovascular function via bioactivation of salivary nitrate. Excessive use of antiseptic mouthwashes may attenuate the bioactivity of dietary nitrate...