Christian Benedict

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. pmc Brain insulin signaling and Alzheimer's disease: current evidence and future directions
    Helgi B Schioth
    Department of Neuroscience, Uppsala University, Box 593, Husargatan 3, Uppsala, Sweden
    Mol Neurobiol 46:4-10. 2012
  2. pmc Acute sleep deprivation delays the glucagon-like peptide 1 peak response to breakfast in healthy men
    C Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Nutr Diabetes 3:e78. 2013
  3. pmc Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence
    Jessica Freiherr
    Department of Diagnostic and Interventional Neuroradiology, RWTH Aachen University, Pauwelsstr 30, 52074 Aachen, Germany
    CNS Drugs 27:505-14. 2013
  4. doi request reprint Association between physical activity and brain health in older adults
    Christian Benedict
    Uppsala University, Department of Neuroscience, Uppsala, Sweden
    Neurobiol Aging 34:83-90. 2013
  5. pmc Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study
    Samantha J Brooks
    Section of Eating Disorders, Institute of Psychiatry, King s College London, London, SE5 8AF UK
    BMC Psychiatry 11:179. 2011
  6. doi request reprint Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study
    Christian Benedict
    Department of Neuroscience, Uppsala University, Box 593, SE 751 24 Uppsala, Sweden
    J Clin Endocrinol Metab 97:E443-7. 2012
  7. pmc Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Diabetes Care 35:488-94. 2012
  8. ncbi request reprint Diurnal rhythm of circulating nicotinamide phosphoribosyltransferase (Nampt/visfatin/PBEF): impact of sleep loss and relation to glucose metabolism
    Christian Benedict
    Department of Neuroscience, Uppsala University, Box 593, SE 751 24 Uppsala, Sweden
    J Clin Endocrinol Metab 97:E218-22. 2012
  9. pmc Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    BMC Immunol 13:1. 2012
  10. doi request reprint The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Neurobiol Aging 32:1159.e1-5. 2011

Detail Information

Publications26

  1. pmc Brain insulin signaling and Alzheimer's disease: current evidence and future directions
    Helgi B Schioth
    Department of Neuroscience, Uppsala University, Box 593, Husargatan 3, Uppsala, Sweden
    Mol Neurobiol 46:4-10. 2012
    ....
  2. pmc Acute sleep deprivation delays the glucagon-like peptide 1 peak response to breakfast in healthy men
    C Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Nutr Diabetes 3:e78. 2013
    ..02).Conclusions:Results indicate that acute TSD exerts a mild, but discernible effect on the postprandial dynamics of circulating GLP-1 concentrations in healthy men. ..
  3. pmc Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence
    Jessica Freiherr
    Department of Diagnostic and Interventional Neuroradiology, RWTH Aachen University, Pauwelsstr 30, 52074 Aachen, Germany
    CNS Drugs 27:505-14. 2013
    ....
  4. doi request reprint Association between physical activity and brain health in older adults
    Christian Benedict
    Uppsala University, Department of Neuroscience, Uppsala, Sweden
    Neurobiol Aging 34:83-90. 2013
    ..These present cross-sectional results indicate that PA is a lifestyle factor that is linked to brain structure and function in late life...
  5. pmc Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study
    Samantha J Brooks
    Section of Eating Disorders, Institute of Psychiatry, King s College London, London, SE5 8AF UK
    BMC Psychiatry 11:179. 2011
    ..This study aimed to provide preliminary extensions of this data by examining how different levels of appetitive restraint impact on brain volume...
  6. doi request reprint Acute sleep deprivation enhances the brain's response to hedonic food stimuli: an fMRI study
    Christian Benedict
    Department of Neuroscience, Uppsala University, Box 593, SE 751 24 Uppsala, Sweden
    J Clin Endocrinol Metab 97:E443-7. 2012
    ..Sleep deprivation is associated with an increase in food consumption and appetite. However, the brain regions that are most susceptible to sleep deprivation-induced changes when processing food stimuli are unknown...
  7. pmc Impaired insulin sensitivity as indexed by the HOMA score is associated with deficits in verbal fluency and temporal lobe gray matter volume in the elderly
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Diabetes Care 35:488-94. 2012
    ....
  8. ncbi request reprint Diurnal rhythm of circulating nicotinamide phosphoribosyltransferase (Nampt/visfatin/PBEF): impact of sleep loss and relation to glucose metabolism
    Christian Benedict
    Department of Neuroscience, Uppsala University, Box 593, SE 751 24 Uppsala, Sweden
    J Clin Endocrinol Metab 97:E218-22. 2012
    ..However, it is unknown whether circulating Nampt concentrations, which are elevated in type 2 diabetes and obesity, display a diurnal rhythm in humans...
  9. pmc Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    BMC Immunol 13:1. 2012
    ..The specific antibody titer in serum was assayed by the hemagglutination inhibition test on the days 5, 10, 17, and 52 following vaccination...
  10. doi request reprint The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Neurobiol Aging 32:1159.e1-5. 2011
    ..This effect was not observed for a measure of general cognitive performance (i.e., Mini-Mental State Examination score), thereby indicating that the FTO gene primarily affects frontal lobe-dependent cognitive processes in elderly men...
  11. doi request reprint Intranasal insulin as a therapeutic option in the treatment of cognitive impairments
    Christian Benedict
    Department of Neuroscience, University of Uppsala, Uppsala, Sweden
    Exp Gerontol 46:112-5. 2011
    ....
  12. ncbi request reprint Mediterranean diet habits in older individuals: associations with cognitive functioning and brain volumes
    Olga E Titova
    Department of Neuroscience, Uppsala University, Sweden Electronic address
    Exp Gerontol 48:1443-8. 2013
    ..Further, they suggest that the MeDi score is a construct that may mask possible associations of single MeDi features with brain health domains in elderly populations. ..
  13. doi request reprint Acute sleep deprivation increases food purchasing in men
    Colin D Chapman
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Obesity (Silver Spring) 21:E555-60. 2013
    ..To investigate if acute sleep deprivation affects food purchasing choices in a mock supermarket...
  14. pmc Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly
    Olga E Titova
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Age (Dordr) 35:1495-505. 2013
    ..These cross-sectional findings suggest that dietary intake of EPA and DHA may be linked to improved cognitive health in late life but must be confirmed in patient studies...
  15. pmc Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly
    Josefin A Jacobsson
    Department of Neuroscience, Functional Pharmacology, Uppsala University, Uppsala, Sweden
    PLoS ONE 6:e20158. 2011
    ..In contrast, this association was not found in elderly men. BMI is a measure of overweight in relation to the individuals' height, but offers no insight into the regional body fat composition or distribution...
  16. doi request reprint Genome wide analysis reveals association of a FTO gene variant with epigenetic changes
    Markus Sällman Almén
    Department of Neuroscience, Functional Pharmacology, Uppsala University, BMC, Uppsala, Sweden
    Genomics 99:132-7. 2012
    ..Our findings suggest that the effect of the FTO obesity risk allele may be mediated through epigenetic changes. Further, these sites might prove to be valuable biomarkers for the understanding of obesity and its comorbidites...
  17. pmc Watching TV and Food Intake: The Role of Content
    Colin D Chapman
    Dept of Neuroscience, Uppsala University, Uppsala, Sweden
    PLoS ONE 9:e100602. 2014
    ..Additionally, they suggest that emotional content (e.g. boring vs. engaging) may be more associated than modality (e.g. TV vs. text) with concurrent intake. ..
  18. ncbi request reprint Acute sleep deprivation increases portion size and affects food choice in young men
    Pleunie S Hogenkamp
    Department of Neuroscience, Uppsala University, 751 24 Uppsala, Sweden Electronic address
    Psychoneuroendocrinology 38:1668-74. 2013
    ..Further, they show that portion size choice after sleep loss depend on both an individual's hunger status, and the type of food offered...
  19. ncbi request reprint Increased impulsivity in response to food cues after sleep loss in healthy young men
    Jonathan Cedernaes
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Obesity (Silver Spring) 22:1786-91. 2014
    ..To investigate whether acute total sleep deprivation (TSD) leads to decreased cognitive control when food cues are presented during a task requiring active attention, by assessing the ability to cognitively inhibit prepotent responses...
  20. pmc Late-life alcohol consumption and cognitive function in elderly men
    Pleunie S Hogenkamp
    Department of Neuroscience, Uppsala University, Box 593, 751 24, Uppsala, Sweden
    Age (Dordr) 36:243-9. 2014
    ..Thus, our findings do not support the view that daily moderate alcohol consumption is a recommendable strategy to slow cognitive aging in elderly populations. ..
  21. pmc Intranasal treatment of central nervous system dysfunction in humans
    Colin D Chapman
    Department of Neuroscience, Uppsala University, Box 593, Husargatan 3, Uppsala, Sweden
    Pharm Res 30:2475-84. 2013
    ....
  22. pmc Lifestyle determinants of the drive to eat: a meta-analysis
    Colin Daniel Chapman
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Am J Clin Nutr 96:492-7. 2012
    ..In addition, studies that investigated the acute impact of these factors on food intake have reported a wide variety of effect sizes, from highly positive to slightly negative...
  23. pmc Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men
    Christian Benedict
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Sleep 37:195-8. 2014
    ..A reduced plasma ratio of Aβ peptides 1-42 to 1-40 is considered an indirect measure of increased deposition of Aβ 1-42 peptide in the brain...
  24. doi request reprint The influence of active and passive smoking during pregnancy on umbilical cord blood levels of vitamins A and E and neonatal anthropometric indices
    Olga E Titova
    Department of Neuroscience, Uppsala University, Box 593, 75124 Uppsala, Sweden
    Br J Nutr 108:1341-5. 2012
    ..However, due to the cross-sectional nature of our observation, this line of reasoning definitely requires validation in cause-effect experiments in the future...
  25. ncbi request reprint Insulin to treat Alzheimer's disease: just follow your nose?
    Helgi B Schioth
    Uppsala University, Department of Neuroscience, Uppsala, Sweden
    Expert Rev Clin Pharmacol 5:17-20. 2012
    ....
  26. pmc A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?
    Samantha Jane Brooks
    Department of Neuroscience, University of Uppsala, Box 593, Uppsala, Sweden
    BMC Psychiatry 12:76. 2012
    ..However, future diagnoses for eating disorders will rely on current advances in the fields of neuroimaging and genetics for classification of symptoms that will ultimately improve treatment...