Erik Axelsson

Summary

Affiliation: Uppsala University
Country: Sweden

Publications

  1. doi request reprint The genomic signature of dog domestication reveals adaptation to a starch-rich diet
    Erik Axelsson
    Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 75237 Uppsala, Sweden
    Nature 495:360-4. 2013
  2. pmc Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome
    Erik Axelsson
    Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 75237 Uppsala, Sweden
    Genome Res 22:51-63. 2012
  3. ncbi request reprint Strong regional biases in nucleotide substitution in the chicken genome
    Matthew T Webster
    Department of Evolution, Genomics and Systematics, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 23:1203-16. 2006
  4. doi request reprint Natural selection in avian protein-coding genes expressed in brain
    Erik Axelsson
    Department of Evolutionary Biology, Uppsala University, Norbyvagen 18D, SE 752 36 Uppsala, Sweden
    Mol Ecol 17:3008-17. 2008
  5. ncbi request reprint Rapid evolution of female-biased, but not male-biased, genes expressed in the avian brain
    Judith E Mank
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 24:2698-706. 2007
  6. pmc Fast-X on the Z: rapid evolution of sex-linked genes in birds
    Judith E Mank
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18 D, SE 752 36 Uppsala, Sweden
    Genome Res 17:618-24. 2007
  7. doi request reprint Quantification of adaptive evolution of genes expressed in avian brain and the population size effect on the efficacy of selection
    Erik Axelsson
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 26:1073-9. 2009
  8. ncbi request reprint Substitution rate heterogeneity and the male mutation bias
    Sofia Berlin
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18 D, Uppsala, SE 752 36, Sweden
    J Mol Evol 62:226-33. 2006
  9. pmc Comparison of the chicken and turkey genomes reveals a higher rate of nucleotide divergence on microchromosomes than macrochromosomes
    Erik Axelsson
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, SE 752 36 Uppsala, Sweden
    Genome Res 15:120-5. 2005

Detail Information

Publications9

  1. doi request reprint The genomic signature of dog domestication reveals adaptation to a starch-rich diet
    Erik Axelsson
    Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 75237 Uppsala, Sweden
    Nature 495:360-4. 2013
    ..Our results indicate that novel adaptations allowing the early ancestors of modern dogs to thrive on a diet rich in starch, relative to the carnivorous diet of wolves, constituted a crucial step in the early domestication of dogs...
  2. pmc Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome
    Erik Axelsson
    Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, 75237 Uppsala, Sweden
    Genome Res 22:51-63. 2012
    ..The genetic determinants of recombination hotspots in the dog genome may thus reflect a fundamental process of relevance to diverse animal species...
  3. ncbi request reprint Strong regional biases in nucleotide substitution in the chicken genome
    Matthew T Webster
    Department of Evolution, Genomics and Systematics, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 23:1203-16. 2006
    ..The results suggest that an interaction between increased mutability at CpG motifs and fixation biases due to BGC could explain increased levels of divergence in GC-rich regions...
  4. doi request reprint Natural selection in avian protein-coding genes expressed in brain
    Erik Axelsson
    Department of Evolutionary Biology, Uppsala University, Norbyvagen 18D, SE 752 36 Uppsala, Sweden
    Mol Ecol 17:3008-17. 2008
    ..Moreover, colouration genes evolve faster in birds than in mammals, which may have been driven by sexual selection for extravagant plumage characteristics...
  5. ncbi request reprint Rapid evolution of female-biased, but not male-biased, genes expressed in the avian brain
    Judith E Mank
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 24:2698-706. 2007
    ....
  6. pmc Fast-X on the Z: rapid evolution of sex-linked genes in birds
    Judith E Mank
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18 D, SE 752 36 Uppsala, Sweden
    Genome Res 17:618-24. 2007
    ..104) and on the autosomes (0.0908). In conjunction, these results suggest that evolution proceeds more quickly on the Z chromosome, where hemizygous exposure of beneficial nondominant mutations increases the rate of fixation...
  7. doi request reprint Quantification of adaptive evolution of genes expressed in avian brain and the population size effect on the efficacy of selection
    Erik Axelsson
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 26:1073-9. 2009
    ..Overall, these results highlight the link between the effective population size and positive as well as negative selection...
  8. ncbi request reprint Substitution rate heterogeneity and the male mutation bias
    Sofia Berlin
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvagen 18 D, Uppsala, SE 752 36, Sweden
    J Mol Evol 62:226-33. 2006
    ..68, p = 0.04). Our results suggest the importance of using extensive data sets from several genomic regions to avoid the effects of regional mutation rate variation and to ensure accurate estimates of alpha(m)...
  9. pmc Comparison of the chicken and turkey genomes reveals a higher rate of nucleotide divergence on microchromosomes than macrochromosomes
    Erik Axelsson
    Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, SE 752 36 Uppsala, Sweden
    Genome Res 15:120-5. 2005
    ..094) are significantly lower than those of macrochromosomes (average, 0.185; P = 0.025), suggesting that the proteins of genes on microchromosomes are under greater evolutionary constraint...