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Species | Rose Marie AminiSummaryAffiliation: Uppsala University Country: Sweden Publications
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Publications
A population-based study of the outcome for patients with first relapse of Hodgkin's lymphomaRose Marie Amini
Department of Oncology and Regional Oncological Centre, University Hospital of Uppsala, Sweden
Eur J Haematol 68:225-32. 2002..Our aims were to evaluate the response to salvage treatment in relation to initial treatment and to evaluate prognostic factors at the time of relapse in an unselected population of relapsing patients with Hodgkin's lymphoma (HL)...
Mast cells and eosinophils in invasive breast carcinomaRose Marie Amini
Department of Genetics and Pathology, Uppsala University Hospital, Uppsala, Sweden
BMC Cancer 7:165. 2007..Inflammatory cells in the tumour stroma has gained increasing interest recently. Thus, we aimed to study the frequency and prognostic impact of stromal mast cells and tumour infiltrating eosinophils in invasive breast carcinomas...
Relationship between Hodgkin's and non-Hodgkin's lymphomasRose Marie Amini
Department of Genetics and Pathology, Uppsala University, Uppsala University Hospital, Uppsala, Sweden
Med Oncol 20:211-20. 2003..It is thus possible that a biological relationship between the disorders may exist in addition to morphological overlaps, and the purpose with this review is to summarize the different relations between HL and NHL...
A novel B-cell line (U-2932) established from a patient with diffuse large B-cell lymphoma following Hodgkin lymphomaRose Marie Amini
Department of Genetics and Pathology, Uppsala University, Uppsala University Hospital, SE 751 85 Uppsala, Sweden
Leuk Lymphoma 43:2179-89. 2002..This cell line may become a useful tool to better understand the mechanisms responsible for development of secondary NHL in patients treated for HL...
Relapsed Hodgkin's lymphoma: immunostaining patterns in relation to survivalRose Marie Amini
Department of Genetics and Pathology, University of Uppsala, Sweden
Leuk Lymphoma 43:1253-60. 2002..We found a significant relation between the expression of p53 and EBV at diagnosis and relapse, indicating a clonal relationship. We were unable to find any specific staining pattern of p53 or Rb, affecting survival...
Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosisMattias Berglund
Department of Oncology, Radiology, and Clinical Immunology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
Mod Pathol 18:1113-20. 2005..Here we confirm the prognostic importance of determining the germinal- or nongerminal center phenotype in patients with DLBCL...
IL-9 expression contributes to the cellular composition in Hodgkin lymphomaIngrid Glimelius
Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden
Eur J Haematol 76:278-83. 2006..The aim of this study was to explore if the expression of IL-9 correlates to the presence of these inflammatory cells in HL tumours...
Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphomaNorafiza Zainuddin
Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden
Leuk Res 35:438-43. 2011..048) in patients <65 years old, the significance of this finding, if any, needs to be further investigated. In conclusion, our finding questions the role of p16(INK4a) promoter methylation as a negative prognostic factor in DLBCL...
Predictors of histology, tissue eosinophilia and mast cell infiltration in Hodgkin's lymphoma--a population-based studyIngrid Glimelius
Department of Radiology, Oncology and Radiation Science Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden
Eur J Haematol 87:208-16. 2011..The aim of this study was to investigate how selected patient characteristics and genetic factors affect HL phenotype, in particular tissue eosinophilia, mast cell counts and HL histological subtype...
Long-term survival of women with basal-like ductal carcinoma in situ of the breast: a population-based cohort studyWenjing Zhou
Department of Surgical Science, Uppsala University, Uppsala, SE 75105, Sweden
BMC Cancer 10:653. 2010..However, the prognosis of basal-like ductal carcinoma in situ (DCIS) is still unknown. Our aim was to study the prognosis of basal-like DCIS in a large population-based cohort...
Characteristics of diffuse large B cell lymphomas in rheumatoid arthritisEva Baecklund
Department of Rheumatology, Akademiska Hospital, Uppsala, Sweden
Arthritis Rheum 54:3774-81. 2006..This study was undertaken to investigate whether RA displays a specific association with any of the DLBCL subtypes...
Tissue microarray and digital image analysis: a methodological study with special reference to the microenvironment in Hodgkin lymphomaIngrid Glimelius
Department of Radiology, Oncology and Radiation Science, Uppsala University, Rudbeck Laboratory, Uppsala, Sweden
Histopathology 61:26-32. 2012..The aim of this study was to compare tissue microarrays (TMA) to whole tissue sections (WS) with regard to cells in the tumour microenvironment. Manual evaluation and digital image analyses (DIA) were utilized and also compared...
Effect of eosinophil cationic protein (ECP) on Hodgkin lymphoma cell linesIngrid Glimelius
Department of Radiology, Oncology and Radiation Sciences, Uppsala University, Uppsala, Sweden
Exp Hematol 39:850-8. 2011..Our aim was to investigate the effects of eosinophil cationic protein (ECP) on HL tumor cells in vitro...
TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtypeNorafiza Zainuddin
Department of Oncology, Radiology and Clinical Immunology, Uppsala University, Uppsala, Sweden
Leuk Res 33:60-6. 2009..002 and PFS, P=0.006). Neither MDM2 SNP309 nor the TP53 codon 72 polymorphism had an impact on age of onset or survival. Altogether, our data suggests that TP53 mutations are associated with poor outcome in GC-DLBCL patients...
Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphomaGustaf Hedström
Department of Oncology, Radiology and Clincial Immunology, Uppsala University, Uppsala, Sweden
Br J Haematol 138:68-71. 2007..03 in both germinal centre (GC) and non-GC DLBCL. This supports the idea that the infiltration of mast cells is a reflection of the host inflammatory response and is related to a favourable outcome...
Low expression of microRNA-129-5p predicts poor clinical outcome in diffuse large B cell lymphoma (DLBCL)Gustav Hedström
Department of Radiology, Oncology, and Radiation Sciences, Uppsala University, Uppsala, Sweden
Int J Hematol 97:465-71. 2013..Further investigations may also help to elucidate the biological role of microRNA-129-5p in DLBCL...
Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphomaMattias Berglund
Department of Molecular Medicine and Surgery, Karolinska University Hospital Solna, Stockholm, Sweden
Mod Pathol 20:63-75. 2007..The findings support diverse genetic background between transformed and de novo DLBCL...
High expression of microRNA-200c predicts poor clinical outcome in diffuse large B-cell lymphomaMattias Berglund
Department of Radiology, Oncology and Radiation Sciences, Uppsala University, Uppsala, Sweden
Oncol Rep 29:720-4. 2013..Further investigations may also help to elucidate the biological role of microRNA-200c in DLBCL...
Bulky disease is the most important prognostic factor in Hodgkin lymphoma stage IIBIngrid Glimelius
Department of Oncology, Radiology, and Clinical Immunology, Rudbeck Laboratory, Uppsala University Hospital, Uppsala, Sweden
Eur J Haematol 71:327-33. 2003..In conclusion, we suggest that bulky disease should be taken into account when treating patients with stage IIB HL...
Cyclin A is a proliferative marker with good prognostic value in node-negative breast cancerCecilia Ahlin
Department of Oncology, Uppsala University Hospital, SE 751 85 Uppsala, Sweden
Cancer Epidemiol Biomarkers Prev 18:2501-6. 2009..Studies suggest that cyclin A is a prognostic marker with satisfying reproducibility. We investigated cyclin A as a prognostic marker in node-negative breast cancer using previously defined cutoff values. Patients and..
Neuroendocrine markers are expressed in human mammary glandsMalin Grönberg
Dept of Medical Sciences, Section of Endocrine Oncology, Uppsala University, SE 751 85 Uppsala, Sweden
Regul Pept 160:68-74. 2010..As these peptides are produced by scattered neuroendocrine cells in the epithelium of other tissues the aim of this study was to investigate whether the mammary glands express molecular markers for neuroendocrine cells...
Analysis of a clonally related mantle cell and Hodgkin lymphoma indicates Epstein-Barr virus infection of a Hodgkin/Reed-Sternberg cell precursor in a germinal centerMarianne Tinguely
Department of Pathology, University of Frankfurt, Germany
Am J Surg Pathol 27:1483-8. 2003..Importantly, the finding that only a subclone of the HRS clone, defined by a particular mutation pattern, was EBV infected represents a strong indication that EBV infection of the HRS cell precursor happened in the GC...
Subtype preference of the BCL6397G/C polymorphism in germinal-center and non-germinal-center subtypes of diffuse large B-cell lymphomaMattias Berglund
Blood 108:3623-4. 2006
Prognostic impact of immunohistochemically defined germinal center phenotype in diffuse large B-cell lymphoma patients treated with immunochemotherapyHeidi Nyman
Department of Oncology, Helsinki University Central Hospital, FIN 00029 Helsinki, Finland
Blood 109:4930-5. 2007..030; FFS, 79% vs 52%, P = .028). We conclude that rituximab in combination with chemotherapy seems to eliminate the prognostic value of immunohistochemically defined GC- and non-GC phenotypes in DLBCL...
Establishment of a cell line from a chemotherapy resistant diffuse large B-cell lymphomaMattias Berglund
Leuk Lymphoma 48:1038-41. 2007
Cigarette smoking and risk of Hodgkin lymphoma: a population-based case-control studyHenrik Hjalgrim
Department of Epidemiology Research, Statens Serum Institut, University of Copenhagen, Artillerivej 5, DK 2300 Copenhagen S, Denmark
Cancer Epidemiol Biomarkers Prev 16:1561-6. 2007..The conflicting finding may reflect etiologic heterogeneity between HL subtypes, warranting further characterization of the relationship...
Familial breast cancers without mutations in BRCA1 or BRCA2 have low cyclin E and high cyclin D1 in contrast to cancers in BRCA mutation carriersKirsimari Aaltonen
Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
Clin Cancer Res 14:1976-83. 2008..Cyclin E expression in tumors of BRCA1 or BRCA2 carriers is higher, and cyclin D1 expression lower, than in sporadic tumors. In familial non-BRCA1/2 tumors, cyclin E and cyclin D1 expression has not been studied...
