Research Topics
| B LagerqvistSummaryAffiliation: University Hospital Country: Sweden Publications
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Detail Information
Publications
Is early invasive treatment of unstable coronary artery disease equally effective for both women and men? FRISC II Study Group InvestigatorsB Lagerqvist
Department of Cardiology, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 38:41-8. 2001....- A long-term perspective on the protective effects of an early invasive strategy in unstable coronary artery disease: two-year follow-up of the FRISC-II invasive studyBo Lagerqvist
Department of Cardiology, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 40:1902-14. 2002..We sought to report the first and repeat events and to separate spontaneous and procedure-related events over two years in the Fast Revascularization during InStability in Coronary artery disease (FRISC-II) invasive trial... 
FRISC score for selection of patients for an early invasive treatment strategy in unstable coronary artery diseaseB Lagerqvist
Department of Medical Sciences, Cardiology, University Hospital, Uppsala, Sweden
Heart 91:1047-52. 2005..To develop a scoring system for risk stratification and evaluation of the effect of an early invasive strategy for treatment of unstable coronary artery disease (CAD)...- Outcome at 1 year after an invasive compared with a non-invasive strategy in unstable coronary-artery disease: the FRISC II invasive randomised trial. FRISC II Investigators. Fast Revascularisation during Instability in Coronary artery diseaseL Wallentin
Department of Cardiology, University Hospital, Uppsala, Sweden
Lancet 356:9-16. 2000..The Fragmin and Fast Revascularisation during Instability in Coronary artery disease II trial (FRISC II) compared an early invasive with an early non-invasive strategy in unstable coronary-artery disease. We report outcome at 1 year... - Mechanisms behind the prognostic value of troponin T in unstable coronary artery disease: a FRISC II substudyB Lindahl
Department of Cardiology, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 38:979-86. 2001..This study was designed to elucidate possible mechanisms for the prognostic value of troponin T (tnT)... 
Long-term safety and efficacy of drug-eluting versus bare-metal stents in SwedenStefan K James
Department of Cardiology, Uppsala University Hospital, Uppsala, Sweden
N Engl J Med 360:1933-45. 2009..The long-term safety and efficacy of drug-eluting coronary stents have been questioned...- Effects on mortality of abciximab in ST-elevation myocardial infarction treated with percutaneous coronary intervention including stent implantationP Tornvall
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
J Intern Med 260:363-8. 2006..To investigate the effects of abciximab on mortality in ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) including stent implantation... - Clinical and angiographic follow-up after coronary drug-eluting and bare metal stent implantation. Do drug-eluting stents hold the promise?J Jensen
Department of Cardiology, Karolinska University Hospital, Solna, Stockholm, Sweden
J Intern Med 260:118-24. 2006..To investigate the influence of drug-eluting stent (DES) implantation on clinical and angiographic restenosis... - Renal failure in 57 925 patients undergoing coronary procedures using iso-osmolar or low-osmolar contrast mediaP Liss
Institute of Radiology, University of Uppsala, Uppsala, Sweden
Kidney Int 70:1811-7. 2006..9%) as ioxaglate. In conclusion, risk of developing renal failure and required dialysis after coronary procedures is higher when patients received iodixanol than ioxaglate or iohexol... - ST depression in ECG at entry indicates severe coronary lesions and large benefits of an early invasive treatment strategy in unstable coronary artery disease; the FRISC II ECG substudy. The Fast Revascularisation during InStability in Coronary artery disE Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Eur Heart J 23:41-9. 2002..In these patients an early invasive strategy substantially decreases death/myocardial infarction... - Early invasive treatment benefits patients with renal dysfunction in unstable coronary artery diseaseNina Johnston
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
Am Heart J 152:1052-8. 2006..Few studies have investigated the effects of an early revascularization in relation to renal function in patients with unstable coronary artery disease (CAD)... - Growth differentiation factor 15 for risk stratification and selection of an invasive treatment strategy in non ST-elevation acute coronary syndromeKai C Wollert
Department of Cardiology and Angiology, Hannover University Medical School, Hannover, Germany
Circulation 116:1540-8. 2007..We hypothesized that the circulating level of growth differentiation factor 15 (GDF-15) may improve risk stratification... - 5-year outcomes in the FRISC-II randomised trial of an invasive versus a non-invasive strategy in non-ST-elevation acute coronary syndrome: a follow-up studyBo Lagerqvist
Department of Cardiology and Uppsala Clinical Research Center, University Hospital, S-751 85 Uppsala, Sweden
Lancet 368:998-1004. 2006..INTERPRETATION: The 5-year outcome of this trial indicates sustained benefit of an early invasive strategy in patients with non-ST-elevation acute coronary syndrome at moderate to high risk... - Early invasive vs conservative treatment strategies in women and men with unstable angina and non-ST-segment elevation myocardial infarction: a meta-analysisMichelle O'Donoghue
TIMI Study Group, Brigham and Women s Hospital, 350 Longwood Ave, First Floor, Boston, MA 02115, USA
JAMA 300:71-80. 2008..Although an invasive strategy is frequently used in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS), data from some trials suggest that this strategy may not benefit women... - Pathophysiologic mechanisms of persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndromeKai M Eggers
Department of Medical Sciences, Cardiology, Uppsala University Hospital, Uppsala, Sweden
Am Heart J 156:588-94. 2008..We now have studied the associations of persistently elevated cTnI levels to cardiac performance, inflammation, coagulation, coronary status, and treatment strategy in these patients... - Oxidized low-density lipoprotein as a predictor of outcome in patients with unstable coronary artery diseaseNina Johnston
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, 751 85 Uppsala, Sweden
Int J Cardiol 113:167-73. 2006..The prognostic value of circulating oxidized low-density lipoprotein (OxLDL) in patients with unstable coronary artery disease (CAD) is unknown... - The prognostic and therapeutic implications of increased troponin T levels and ST depression in unstable coronary artery disease: the FRISC II invasive troponin T electrocardiogram substudyErik Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Am Heart J 143:760-7. 2002.... - Quantitative analysis of the admission electrocardiogram identifies patients with unstable coronary artery disease who benefit the most from early invasive treatmentLene Holmvang
The Heart Center 2141, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
J Am Coll Cardiol 41:905-15. 2003..The present study is a sub-study of the previously published Fast Revascularization during InStability in Coronary artery disease trial (FRISC-II)... - Clinical and analytical performance of the liaison cardiac troponin I assay in unstable coronary artery disease, and the impact of age on the definition of reference limits. A FRISC-II substudyPer Venge
Department of Medical Sciences, University of Uppsala, SE 751 85 Uppsala, Sweden
Clin Chem 49:880-6. 2003..Our aim was to evaluate the clinical and analytical performance of the Liaison cardiac troponin I (cTnI) assay... - The relation of QT dispersion and localized QT difference to coronary pathology in a population with unstable coronary artery diseaseMilos Kesek
Department of Cardiology, Norrland University Hospital, 90185 Umea, Sweden
Ann Noninvasive Electrocardiol 8:22-9. 2003..In order to elucidate a possible local mechanism, we investigated the relation between QT dispersion, an ECG parameter reflecting the local dispersion, and angiographical measures in a population with unstable coronary artery disease... - Effects of an early invasive strategy on ischemia and exercise tolerance among patients with unstable coronary artery diseaseErik Diderholm
Department of Cardiology, University Hospital, Uppsala, Sweden
Am J Med 115:606-12. 2003..An early invasive approach after an episode of unstable coronary artery disease has beneficial effects on mortality and myocardial infarction, but its effects on exercise capacity and ischemia have not been investigated... - N-terminal pro-brain natriuretic peptide in relation to inflammation, myocardial necrosis, and the effect of an invasive strategy in unstable coronary artery diseaseTomas Jernberg
Department of Medical Sciences, Cardiology, Cardiothoracic Center, University Hospital, Uppsala, Sweden
J Am Coll Cardiol 42:1909-16. 2003.... - Diabetes mellitus: the major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularizationAnna Norhammar
Department of Cardiology, Karolinska Hospital, Stockholm, Sweden
J Am Coll Cardiol 43:585-91. 2004..This study was designed to study the influence of diabetes on the outcome of unstable coronary artery disease (CAD)... - Consideration of the total ST-segment deviation on the initial electrocardiogram for predicting final acute posterior myocardial infarct size in patients with maximum ST-segment deviation as depression in leads V1 through V3. A FRISC II substudyRasmus S Ripa
Division of Cardiology, Duke University Medical Center, Durham, NC 27705, USA
J Electrocardiol 38:180-6. 2005..The formula derived could be valuable for selecting patients who fail to meet strict ST-elevation AMI criteria for emergency intravenous or intracoronary reperfusion therapy... - Long-term outcomes with drug-eluting stents versus bare-metal stents in SwedenBo Lagerqvist
Uppsala Clinical Research Center, Uppsala University Hospital, Uppsala, Sweden
N Engl J Med 356:1009-19. 2007..Recent reports have indicated that there may be an increased risk of late stent thrombosis with the use of drug-eluting stents, as compared with bare-metal stents... - Cardiovascular risk factors for stable angina pectoris versus unheralded myocardial infarctionKristina Dunder
Department of Public Health and Caring Sciences Geriatrics, Uppsala University, Uppsala, Sweden
Am Heart J 147:502-8. 2004..This study compared baseline risk factors between subjects in whom stable angina pectoris developed and subjects in whom unheralded fatal or nonfatal MI developed during the follow-up period... - Persistent cardiac troponin I elevation in stabilized patients after an episode of acute coronary syndrome predicts long-term mortalityKai M Eggers
Department of Medical Sciences, Cardiology, University Hospital Uppsala, S 751 85 Uppsala, Sweden
Circulation 116:1907-14. 2007..However, the prevalence and prognostic importance of persistent troponin elevation in stabilized patients after an episode of non-ST-elevation acute coronary syndrome are unknown and were therefore assessed in this study... - Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkersNina Johnston
The Division of Medical Sciences, Department of Cardiology, University Hospital, Uppsala, Sweden
Am J Cardiol 97:640-5. 2006.... - Genetic variations in the tissue factor gene are associated with clinical outcome in acute coronary syndrome and expression levels in human monocytesAnders Malarstig
Division of Clinical Chemistry, Department of Medical Sciences, Uppsala University, Uppsala, Sweden
Arterioscler Thromb Vasc Biol 25:2667-72. 2005..Moreover, we wanted to investigate the impact of associated TF SNPs on mRNA production in human monocytes...