Research Topics
Species | Anna DahlénSummaryAffiliation: University Hospital Country: Sweden Publications
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Detail Information
Publications
Analysis of the distribution and frequency of trisomy 7 in vivo in synovia from patients with osteoarthritis and pigmented villonodular synovitisA Dahlen
Department of Clinical Genetics, University Hospital, SE 221 85, Lund, Sweden
Cancer Genet Cytogenet 131:19-24. 2001..By hematoxylin-eosin staining of the slides used for FISH analysis it could be shown that the clustered trisomic cells were proliferating synoviocytes within villous extensions of the synovial membrane...
Clustering of deletions on chromosome 13 in benign and low-malignant lipomatous tumorsAnna Dahlén
Department of Clinical Genetics, University Hospital, Lund, Sweden
Int J Cancer 103:616-23. 2003..Our findings strongly indicate that deletion of a limited region (approximately 2.5 Mbp) within 13q14, distal to the RB1-locus, is of importance in the development of a subset of lipomatous tumors...
Fusion, disruption, and expression of HMGA2 in bone and soft tissue chondromasAnna Dahlén
Department of Clinical Genetics, University Hospital, Lund, Sweden
Mod Pathol 16:1132-40. 2003..A truncated or full-length transcript was found in 8 of 13 chondrosarcomas, 4 of which displayed 12q rearrangements. Possibly, cryptic rearrangements were present among the many complex marker chromosomes in the remaining 4 cases...
Activation of the GLI oncogene through fusion with the beta-actin gene (ACTB) in a group of distinctive pericytic neoplasms: pericytoma with t(7;12)Anna Dahlén
Department of Clinical Genetics, University Hospital, Lund, Sweden
Am J Pathol 164:1645-53. 2004....
Molecular genetic characterization of the genomic ACTB-GLI fusion in pericytoma with t(7;12)Anna Dahlén
Department of Clinical Genetics, University Hospital, SE 221 85 Lund, Sweden
Biochem Biophys Res Commun 325:1318-23. 2004..Whereas large repeats or recombinase recognition sequences were not detected, sequences of shared oligonucleotides, possibly important for recombination, were found in the proximity of the respective breakpoints...
Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapyJens Engleson
Department of Oncology, Lund University Hospital, SE 221 85, Lund, Sweden
BMC Cancer 6:69. 2006..This tumor affects young individuals, shows a rapidly fatal clinical course despite intensive therapy. The t(15;19) results in the fusion oncogene BRD4-NUT. Information concerning treatment of this rare disorder is scarce...
Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimeraIoannis Panagopoulos
Department of Clinical Genetics, University Hospital, Lund, Sweden
Genes Chromosomes Cancer 46:181-91. 2007..Thus, studies regarding the pathways influenced by wild-type CREB3L2 should provide valuable clues to the pathogenetic significance of the FUS/CREB3L2 chimera in low grade fibromyxoid sarcoma...
