Research Topics
| B A KällénSummaryAffiliation: Tornblad Institute Country: Sweden Publications
| Collaborators
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Detail Information
Publications
Associated malformations in infants and fetuses with upper or lower neural tube defectsB Kälién
Tornblad Institute, University of Lund, Sweden
Teratology 57:56-63. 1998..These findings together with other epidemiological data support the idea that upper and lower neural tube defects may have different significance in epidemiological studies and should be treated separately...- Neonate characteristics after maternal use of antidepressants in late pregnancyBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Arch Pediatr Adolesc Med 158:312-6. 2004..Exposure to antidepressants during the third trimester of pregnancy has been associated with an increased risk for adverse birth outcomes, including preterm birth, respiratory distress, and hypoglycemia... - Use of folic acid supplementation and risk for dizygotic twinningBengt Kallen
Tornblad Institute, University of Lund, Biskopsgatan 7, SE 223 62 Lund, Sweden
Early Hum Dev 80:143-51. 2004..An increase in dizygotic twinning rate after folic acid supplementation has previously been described, but in a recent study from China, no such effect was seen... - In vitro fertilization (IVF) in Sweden: risk for congenital malformations after different IVF methodsBengt Kallen
Tornblad Institute, University of Lund, Biskopsgatan 7, SE 223 62 Lund, Sweden
Birth Defects Res A Clin Mol Teratol 73:162-9. 2005..This population based study is aimed at analyzing the presence of congenital malformations in a large group of infants born after IVF and to compare malformation risk both with that of all infants born and according to IVF method used... 
Temporal trends in multiple births after in vitro fertilisation in Sweden, 1982-2001: a register studyBengt Kallen
Centre for Reproduction Epidemiology, Tornblad Institute, University of Lund, Biskopsgatan 7, S 223 62 Lund, Sweden
BMJ 331:382-3. 2005- Methodological issues in the epidemiological study of the teratogenicity of drugsBengt A J Källén
Center for Reproduction Epidemiology, Tornblad Institute, University of Lund, SE 223 62 Lund, Sweden
Congenit Anom (Kyoto) 45:44-51. 2005..Nearly every finding of a risk increase, if not extremely strong, should only be regarded as a tentative signal to be tested in independent studies... - Is erythromycin therapy teratogenic in humans?Bengt A J Källén
Tornblad Institute, Lund University, Biskospgatan 7, SE 22362 Lund, Sweden
Reprod Toxicol 20:209-14. 2005..Potent blocking drugs cause as a class effect cardiac defects in animal experiments... - The epidemiology of anophthalmia and microphthalmia in SwedenBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Eur J Epidemiol 20:345-50. 2005..Maternal smoking in early pregnancy seemed to increase the risk for anophthalmia or microphthalmia in the absence of a coloboma... - In vitro fertilization in Sweden: child morbidity including cancer riskBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Fertil Steril 84:605-10. 2005..To study long-term morbidity among children conceived by IVF... - Maternal drug use, fertility problems, and infant craniostenosisBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Cleft Palate Craniofac J 42:589-93. 2005..In order to validate some findings, data from the Central-East France Registry were studied for first trimester drug exposure in 235 infants, and use of ovarian stimulation in 315 infants with craniostenosis... - In vitro fertilization in Sweden: maternal characteristicsBengt Kallen
Tornblad Institute, University of Lund, Biskopsgatan 7, SE 223 62 Lund, Sweden
Acta Obstet Gynecol Scand 84:1185-91. 2005..Deliveries among women who had an in vitro fertilization (IVF) are characterized by increased risks for both the mother and the infant/child. Part of these effects may be due to maternal characteristics... - Valproic acid is known to cause hypospadias in man but does not reduce anogenital distance or causes hypospadias in ratsBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Basic Clin Pharmacol Toxicol 94:51-4. 2004..The mechanism through which valproic acid causes hypospadias in man and affects testicular development in rat is unknown. Hypospadias caused by valproic acid in man is apparently not due to anti-androgenic properties of the drug... - Maternal drug use and infant cleft lip/palate with special reference to corticoidsBengt Kallen
Tornblad Institute, University of Lund, Sweden
Cleft Palate Craniofac J 40:624-8. 2003..To study the association between maternal drug use in early pregnancy and orofacial cleft in the infant... - Congenital malformations after the use of inhaled budesonide in early pregnancyB Kallen
Tornblad Institute, and the Department of Obstetrics and Gynecology, University of Lund, Sweden
Obstet Gynecol 93:392-5. 1999..To study possible teratogenic risks with the use of an inhaled glucocorticoid, budesonide, in early pregnancy... - Asthma during pregnancy--a population based studyB Kallen
Tornblad Institute, Lund, Sweden
Eur J Epidemiol 16:167-71. 2000..An association with preeclampsia, gestational diabetes, and infant hypoglycemia was verified. Maternal asthma appears to be a risk factor for preterm and postterm births and increases the risk for some pregnancy complications... - Drinking water chlorination and delivery outcome-a registry-based study in SwedenB A Källén
Tornblad Institute, University of Lund, S 223 62, Lund, Sweden
Reprod Toxicol 14:303-9. 2000..Because the exposure information in this study was based on the chlorination method and not the amount of byproducts in the water, the general lack of significant effects could be due to a low concentration of such byproducts... - Use of omeprazole during pregnancy--no hazard demonstrated in 955 infants exposed during pregnancyB A Källén
Tornblad Institute, University of Lund, Biskopsgatan 7, S 223 63, Lund, Sweden
Eur J Obstet Gynecol Reprod Biol 96:63-8. 2001..To evaluate the magnitude of possible fetal risks involved in maternal use of omeprazole during pregnancy... - Use of folic acid and delivery outcome: a prospective registry studyBengt A J Källén
Tornblad Institute, University of Lund, Lund, Sweden
Reprod Toxicol 16:327-32. 2002..Our results support the scepticism recently expressed in the literature on the beneficial effect of folic acid in preventing congenital malformations, especially of a non-neural tube defect type... - Neonatal outcome in pregnancies from ovarian stimulationB Kallen
Tornblad Institute, University of Lund, Sweden
Obstet Gynecol 100:414-9. 2002..The outcomes studied were multiple birth, preterm birth, and low birth weight among singletons, congenital malformations, and infant death... - Maternal drug use in early pregnancy and infant cardiovascular defectBengt A J Källén
Center of Reproduction Epidemiology, Tornblad Institute, University of Lund, Biskopsgatan 7, SE 223 62, Lund, Sweden
Reprod Toxicol 17:255-61. 2003..Some of these associations are probably due to confounding from underlying disease or complaint, some may be due to multiple testing, some may be true drug effects. Further studies are needed to verify or reject these associations... - Delivery outcome after the use of meclozine in early pregnancyBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Eur J Epidemiol 18:665-9. 2003..If anything, delivery outcome is better than expected when the mother used meclozine. These beneficial effects are probably secondary to NVP. Meclozine can apparently be used without risk at this condition... - Relationship between vitamin use, smoking, and nausea and vomiting of pregnancyBengt Kallen
Tornblad Institute, University of Lund, Lund, Sweden
Acta Obstet Gynecol Scand 82:916-20. 2003..Nausea and vomiting in pregnancy (NVP) is a common complaint but risk factors for NVP are not well characterized... - Use of oral decongestants during pregnancy and delivery outcomeBengt A J Källén
Tornblad Institute, University of Lund, Lund, Sweden
Am J Obstet Gynecol 194:480-5. 2006..The purpose of this study was to evaluate delivery outcome after maternal use of oral decongestants... - A modified method for the epidemiological analysis of registry data on infants with multiple malformationsK B Källén
Tornblad Institute, University of Lund, Sweden
Int J Epidemiol 28:701-10. 1999..Various methods for the analysis of multimalformed infants have been tried...