Elisabeth Tarkowski

Summary

Country: Sweden

Publications

  1. ncbi Correlation between intrathecal sulfatide and TNF-alpha levels in patients with vascular dementia
    E Tarkowski
    Department of Rheumatology, University of Goteborg, Goteborg, Sweden
    Dement Geriatr Cogn Disord 15:207-11. 2003
  2. ncbi Cerebral pattern of pro- and anti-inflammatory cytokines in dementias
    Elisabeth Tarkowski
    Department of Rheumatology, Section of Neurology and Neurochemistry, University of Goteborg, S 413 46 Goteborg, Sweden
    Brain Res Bull 61:255-60. 2003
  3. ncbi Local and systemic GM-CSF increase in Alzheimer's disease and vascular dementia
    E Tarkowski
    Department of Rheumatology, University of Goteborg, Sweden
    Acta Neurol Scand 103:166-74. 2001
  4. ncbi Decreased levels of intrathecal interleukin 1 receptor antagonist in Alzheimer's disease
    E Tarkowski
    Department of Rheumatology, Department of Clinical Neurosciences, University of Goteborg, Guldhedsgatan 10, S 413 46 Goteborg, Sweden
    Dement Geriatr Cogn Disord 12:314-7. 2001
  5. ncbi Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia
    Elisabeth Tarkowski
    Department of Rheumatology, University of Goteborg, Goteborg, Sweden
    Neurobiol Aging 23:237-43. 2002
  6. ncbi Normal pressure hydrocephalus triggers intrathecal production of TNF-alpha
    E Tarkowski
    Department of Rheumatology and Neurology, University of Goteborg, Guldhedsgatan 10, S 413 46, Goteborg, Sweden
    Neurobiol Aging 24:707-14. 2003
  7. pmc Intrathecal inflammation precedes development of Alzheimer's disease
    E Tarkowski
    Department of Rheumatology, University of Goteborg, Goteborg, Sweden
    J Neurol Neurosurg Psychiatry 74:1200-5. 2003
  8. ncbi Cytokines in dementias
    Elisabeth Tarkowski
    Department of Rheumatology, University of Goteborg, Guldhedsgatan 10, S 413 46 Goteborg, Sweden
    Curr Drug Targets Inflamm Allergy 1:193-200. 2002

Detail Information

Publications8

  1. ncbi Correlation between intrathecal sulfatide and TNF-alpha levels in patients with vascular dementia
    E Tarkowski
    Department of Rheumatology, University of Goteborg, Goteborg, Sweden
    Dement Geriatr Cogn Disord 15:207-11. 2003
    ..The intrathecal TNF-alpha levels were related to the clinical symptoms of dementia, as well as to intrathecal levels of sulfatide, a marker of white matter degradation, and of neurofilament, a marker of neuronal degeneration...
  2. ncbi Cerebral pattern of pro- and anti-inflammatory cytokines in dementias
    Elisabeth Tarkowski
    Department of Rheumatology, Section of Neurology and Neurochemistry, University of Goteborg, S 413 46 Goteborg, Sweden
    Brain Res Bull 61:255-60. 2003
    ..Our results, which show for the first time strikingly increased CSF levels of TNF-alpha but not of TNF-beta, IL-1beta or IL-6 in AD and VAD, may form a conceptual framework for further studies of neuroprotective mechanisms in dementias...
  3. ncbi Local and systemic GM-CSF increase in Alzheimer's disease and vascular dementia
    E Tarkowski
    Department of Rheumatology, University of Goteborg, Sweden
    Acta Neurol Scand 103:166-74. 2001
    ..It is suggested that GM-CSF once secreted induces programmed cell death in the brain tissue of patients with dementia...
  4. ncbi Decreased levels of intrathecal interleukin 1 receptor antagonist in Alzheimer's disease
    E Tarkowski
    Department of Rheumatology, Department of Clinical Neurosciences, University of Goteborg, Guldhedsgatan 10, S 413 46 Goteborg, Sweden
    Dement Geriatr Cogn Disord 12:314-7. 2001
    ..Our study demonstrates a decreased production of the anti-inflammatory compound IL-1ra, suggesting a propensity towards inflammation in patients with AD...
  5. ncbi Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia
    Elisabeth Tarkowski
    Department of Rheumatology, University of Goteborg, Goteborg, Sweden
    Neurobiol Aging 23:237-43. 2002
    ..In addition, we show in AD and VAD an intrathecal production of TGF-beta, a cytokine exerting on one hand anti-inflammatory and angiogenic properties, but on the other promoting amyloidogenesis...
  6. ncbi Normal pressure hydrocephalus triggers intrathecal production of TNF-alpha
    E Tarkowski
    Department of Rheumatology and Neurology, University of Goteborg, Guldhedsgatan 10, S 413 46, Goteborg, Sweden
    Neurobiol Aging 24:707-14. 2003
    ..The positive correlation between preoperative TNF-alpha and sulfatide levels in the CSF suggest that intrathecal TNF-alpha may contribute to the damage of the white matter known to occur in patients with NPH...
  7. pmc Intrathecal inflammation precedes development of Alzheimer's disease
    E Tarkowski
    Department of Rheumatology, University of Goteborg, Goteborg, Sweden
    J Neurol Neurosurg Psychiatry 74:1200-5. 2003
    ....
  8. ncbi Cytokines in dementias
    Elisabeth Tarkowski
    Department of Rheumatology, University of Goteborg, Guldhedsgatan 10, S 413 46 Goteborg, Sweden
    Curr Drug Targets Inflamm Allergy 1:193-200. 2002
    ..This review will focus on the production of pro-inflammatory and anti-inflammatory cytokines in dementia, and their putative role for glia cell activation, amyloidogenesis, vascular changes, white matter damage and neurodegeneration...