W Engstrom

Summary

Affiliation: Swedish University of Agricultural Sciences
Country: Sweden

Publications

  1. ncbi request reprint Effects of insulin-like growth factor binding protein 7 on apoptosis in human teratocarcinoma cells in vitro
    Wilhelm Engstrom
    Division of Pathology, Pharmacology and Toxicology, Department of Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, PO Box 7028, 75007 Uppsala, Sweden
    Anticancer Res 30:911-4. 2010
  2. ncbi request reprint The expression of the insulin-like growth factor II, JIP-1 and WT1 genes in porcine nephroblastoma
    Wilhelm Engstrom
    Division of Pathology, Pharmacology and Toxicology, Department of Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, PO Box 7028, 75007 Uppsala, Sweden
    Anticancer Res 29:4999-5003. 2009
  3. doi request reprint The role of scaffold proteins in JNK signalling
    W Engstrom
    Department of Zoology, University of Oxford, Oxford, UK
    Cell Prolif 43:56-66. 2010
  4. ncbi request reprint Expression of JNK-interacting protein JIP-1 and insulin-like growth factor II in Wilms tumour cell lines and primary Wilms tumours
    Wilhelm Engstrom
    Division of Pathology, Department of Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, 75007 Uppsala, Sweden
    Anticancer Res 29:2467-72. 2009
  5. ncbi request reprint Effects of fibroblast growth factors 19 and 20 on cell multiplication and locomotion in a human embryonal carcinoma cell line (Tera-2) in vitro
    Wilhelm Engstrom
    Department of Biosciences and Veterinary Public Health, Swedish University of Agricultural Sciences, S 750 07 Uppsala, Sweden
    Anticancer Res 26:3307-10. 2006
  6. ncbi request reprint The JNK interacting protein JIP-1 and insulin like growth factor II genes are co-expressed in human embryonic tumours
    Wilhelm Engstrom
    Division of Pathology, Pharmacology and Toxicology, Department of Biomedical Sciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Anticancer Res 25:1075-8. 2005
  7. pmc Insulin-like growth factors I and II induce cell death in Wilms's tumour cells
    M Granerus
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala
    Mol Pathol 54:30-5. 2001
  8. pmc A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor
    K Otte
    Department of Pathology, Swedish University of Agricultural Sciences, PO Box 7028, 75007 Uppsala, Sweden
    Nucleic Acids Res 26:1605-12. 1998
  9. ncbi request reprint Transcriptional regulation and biological significance of the insulin like growth factor II gene
    W Engstrom
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Cell Prolif 31:173-89. 1998
  10. ncbi request reprint Cloning and sequencing of an equine insulin-like growth factor I cDNA and its expression in fetal and adult tissues
    K Otte
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Gen Comp Endocrinol 102:11-5. 1996

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Effects of insulin-like growth factor binding protein 7 on apoptosis in human teratocarcinoma cells in vitro
    Wilhelm Engstrom
    Division of Pathology, Pharmacology and Toxicology, Department of Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, PO Box 7028, 75007 Uppsala, Sweden
    Anticancer Res 30:911-4. 2010
    ..This further suggests that IGF-II rescues cells from apoptosis and that IGFBP-7 is a specific antagonist...
  2. ncbi request reprint The expression of the insulin-like growth factor II, JIP-1 and WT1 genes in porcine nephroblastoma
    Wilhelm Engstrom
    Division of Pathology, Pharmacology and Toxicology, Department of Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, PO Box 7028, 75007 Uppsala, Sweden
    Anticancer Res 29:4999-5003. 2009
    ..In this respect, porcine nephroblastomas resemble human Wilms tumours. This further suggests that JIP-1 may play a role in the regulation of IGF-II-driven tumour cell proliferation...
  3. doi request reprint The role of scaffold proteins in JNK signalling
    W Engstrom
    Department of Zoology, University of Oxford, Oxford, UK
    Cell Prolif 43:56-66. 2010
    ..We believe that some of these scaffold proteins, by virtue of their anchoring and catalytic properties contribute to a high degree of specificity of intra cellular signalling pathways that regulate the progression through the cell cycle...
  4. ncbi request reprint Expression of JNK-interacting protein JIP-1 and insulin-like growth factor II in Wilms tumour cell lines and primary Wilms tumours
    Wilhelm Engstrom
    Division of Pathology, Department of Biosciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, 75007 Uppsala, Sweden
    Anticancer Res 29:2467-72. 2009
    ..These data suggest that JIP-1 has a more complex role in the regulation of proliferation as well as programmed cell death...
  5. ncbi request reprint Effects of fibroblast growth factors 19 and 20 on cell multiplication and locomotion in a human embryonal carcinoma cell line (Tera-2) in vitro
    Wilhelm Engstrom
    Department of Biosciences and Veterinary Public Health, Swedish University of Agricultural Sciences, S 750 07 Uppsala, Sweden
    Anticancer Res 26:3307-10. 2006
    ..The effects of two recently discovered heparin binding growth factors, FGF-19 and FGF-20, on the human embryonal carcinoma derived cell line Tera 2 were examined...
  6. ncbi request reprint The JNK interacting protein JIP-1 and insulin like growth factor II genes are co-expressed in human embryonic tumours
    Wilhelm Engstrom
    Division of Pathology, Pharmacology and Toxicology, Department of Biomedical Sciences and Veterinary Public Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Anticancer Res 25:1075-8. 2005
    ..This finding further supports the notion that JIP-1 and IGF II act in concert to enhance cell proliferation...
  7. pmc Insulin-like growth factors I and II induce cell death in Wilms's tumour cells
    M Granerus
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala
    Mol Pathol 54:30-5. 2001
    ..To study the effects of insulin-like growth factors (IGFs) on the growth phenotype of a Wilms's tumour cell line (WCCS-1)...
  8. pmc A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor
    K Otte
    Department of Pathology, Swedish University of Agricultural Sciences, PO Box 7028, 75007 Uppsala, Sweden
    Nucleic Acids Res 26:1605-12. 1998
    ..Both in horse and mouse, a methylation-sensitive protein binds this structure with a strong requirement for the loop area. Furthermore, the protein might be developmentally regulated...
  9. ncbi request reprint Transcriptional regulation and biological significance of the insulin like growth factor II gene
    W Engstrom
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Cell Prolif 31:173-89. 1998
    ..This paper aims at reviewing how the transcription of the IGF genes is regulated. The biological significance of these control mechanisms will be discussed...
  10. ncbi request reprint Cloning and sequencing of an equine insulin-like growth factor I cDNA and its expression in fetal and adult tissues
    K Otte
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Gen Comp Endocrinol 102:11-5. 1996
    ..The nucleotide homology across the entire clone was 96.3% between horse and man and 91.6% between horse and rat. The isolated cDNA hybridized to the same transcripts in fetal and adult tissues...
  11. ncbi request reprint Insulin-like growth factor II in the horse: determination of a cDNA nucleotide sequence and expression in fetal and adult tissue
    K Otte
    Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala
    Gen Comp Endocrinol 96:270-5. 1994
    ..1% between horse and human and 87.8% between horse and mouse. The isolated cDNA hybridized to multiple transcripts in fetal and adult tissues, thus confirming earlier reports on developmental expression of this gene in the horse...
  12. ncbi request reprint Major ampullate spidroins from Euprosthenops australis: multiplicity at protein, mRNA and gene levels
    A Rising
    Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Insect Mol Biol 16:551-61. 2007
    ..australis. Finally, the evolution of spidroin genes is discussed in relation to phylogenetic analysis of nonrepetitive C-terminal domains from diverse species...