Affiliation: Sundsvall Hospital
- Serum erythropoietin (EPO) levels correlate with survival and independently predict response to EPO treatment in patients with myelodysplastic syndromesJonas Wallvik
Division of Hematology, Department of Medicine, Sundsvall Hospital, Sweden
Eur J Haematol 68:180-5. 2002..007). Our data facilitate the optimal selection of MDS patients suitable for EPO treatment and pinpoint S-EPO as a powerful predictor of response and overall survival in MDS...
- Bleeding complications during warfarin treatment in primary healthcare centres compared with anticoagulation clinicsJonas Wallvik
Division of Hematology, Department of Medicine at Sundsvall Hospital, Sundsvall, Sweden
Scand J Prim Health Care 25:123-8. 2007..To examine determinants of bleeding complications during warfarin treatment in an unselected patient population and evaluate possible differences in safety between specialized anticoagulation clinics and primary healthcare centres...
- Quality of life, physical function and MRI T2* in elderly low-risk MDS patients treated to a haemoglobin level of ≥120 g/L with darbepoetin alfa ± filgrastim or erythrocyte transfusionsHerman Nilsson-Ehle
Section of Hematology and Coagulation, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Eur J Haematol 87:244-52. 2011..The objective for this prospective phase II Nordic multicentre trial was to assess QoL, response rate and physical function in elderly anaemic MDS patients treated to a target Hb level of >120 g/L...
- Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapyMichael Grövdal
Division of Haematology, Department of Medicine, Centre for Experimental Haematology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
Br J Haematol 150:293-302. 2010..5 and 30% of the cycles, respectively, while haemoglobin levels increased during treatment. 5-azacytidine treatment is safe, feasible and may be of benefit in a subset of patients...
- Oral cladribine for B-cell chronic lymphocytic leukaemia: report of a phase II trial with a 3-d, 3-weekly schedule in untreated and pretreated patients, and a long-term follow-up of 126 previously untreated patientsKarin Karlsson
Department of Haematology, University Hospital, Linkoping, Sweden
Br J Haematol 116:538-48. 2002..Cladribine used as a single agent is an effective treatment with an acceptable safety profile for pretreated and untreated B-CLL. The achievement of complete remission was not a prerequisite for long-term survival...
- Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndromeMichael Grövdal
Division of Haematology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Denmark
Clin Cancer Res 13:7107-12. 2007..This study was designed to assess the effect of methylation status on the outcome of conventional induction chemotherapy...