M Abedi-Valugerdi

Summary

Affiliation: Stockholm University
Country: Sweden

Publications

  1. pmc Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice
    M Abedi-Valugerdi
    Department of Biochemistry and Biophysics, Arrhenius Laboratories for the Natural Sciences, Stockholm University, S 106 91 Stockholm, Sweden
    Clin Exp Immunol 141:238-47. 2005
  2. pmc Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?
    M Abedi-Valugerdi
    Department of Biochemistry and Biophysics, Arrhenius Laboratories for the Natural Sciences, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 155:117-24. 2009
  3. ncbi request reprint Longevity of immune complexes and abnormal germinal centre formation in NZB mice
    E Nordstrom
    Department of Immunology, Arrhenius Laboratories for Natural Sciences, Stockholm University, Sweden
    Scand J Immunol 52:477-82. 2000
  4. doi request reprint GVHD after chemotherapy conditioning in allogeneic transplanted mice
    B Sadeghi
    Experimental Cancer Medicine, Institution for Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Bone Marrow Transplant 42:807-18. 2008
  5. ncbi request reprint Mercuric chloride induces a strong immune activation, but does not accelerate the development of dermal fibrosis in tight skin 1 mice
    M Hansson
    Department of Immunology, The Wenner Gren Institute, Arrhenius Laboratories for the Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 59:469-77. 2004
  6. doi request reprint Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?
    B Sadeghi
    Experimental Cancer Medicine, Institution for Laboratory Medicine, Karolinska Institute, Stockholm, Sweden
    Bone Marrow Transplant 48:284-93. 2013
  7. pmc Xenobiotic metal-induced autoimmunity: mercury and silver differentially induce antinucleolar autoantibody production in susceptible H-2s, H-2q and H-2f mice
    M Hansson
    Department of Immunology, The Wenner Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 131:405-14. 2003
  8. doi request reprint Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion
    S al Hashmi
    Experimental Cancer Medicine ECM, Department for Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Bone Marrow Transplant 48:843-8. 2013
  9. ncbi request reprint Spontaneous downregulation of antibody/autoantibody synthesis in susceptible mice upon chronic exposure to mercuric chloride is not owing to a general immunosuppression
    S Roether
    Department of Immunology, The Wenner Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 55:493-502. 2002
  10. ncbi request reprint Genetic control of resistance to mercury-induced immune/autoimmune activation
    M Abedi-Valugerdi
    Department of Immunology, The Wenner-Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 54:190-7. 2001

Collaborators

Detail Information

Publications15

  1. pmc Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice
    M Abedi-Valugerdi
    Department of Biochemistry and Biophysics, Arrhenius Laboratories for the Natural Sciences, Stockholm University, S 106 91 Stockholm, Sweden
    Clin Exp Immunol 141:238-47. 2005
    ..In summary, our findings indicate that activation of the innate immune system plays a key role in both the induction and severity of chemically induced autoimmunity...
  2. pmc Mercury and silver induce B cell activation and anti-nucleolar autoantibody production in outbred mouse stocks: are environmental factors more important than the susceptibility genes in connection with autoimmunity?
    M Abedi-Valugerdi
    Department of Biochemistry and Biophysics, Arrhenius Laboratories for the Natural Sciences, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 155:117-24. 2009
    ..Thus, the findings of this study suggest that long-term exposure to certain environmental factors can activate the immune system to produce autoimmunity per se, without requiring specific susceptible genes...
  3. ncbi request reprint Longevity of immune complexes and abnormal germinal centre formation in NZB mice
    E Nordstrom
    Department of Immunology, Arrhenius Laboratories for Natural Sciences, Stockholm University, Sweden
    Scand J Immunol 52:477-82. 2000
    ..The clearance of immune complexes from the spleen coincided with the decline in serum levels of IgG1-RF, indicating that prolonged retention of immune complexes is responsible for the sustained IgG1-RF response...
  4. doi request reprint GVHD after chemotherapy conditioning in allogeneic transplanted mice
    B Sadeghi
    Experimental Cancer Medicine, Institution for Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Bone Marrow Transplant 42:807-18. 2008
    ..We report a mouse model of GVHD using BU-CY conditioning that represents the most common myeloablative-conditioning regimen in clinical SCT. This model can be utilized to study the role of conditioning on mechanisms underlying GVHD...
  5. ncbi request reprint Mercuric chloride induces a strong immune activation, but does not accelerate the development of dermal fibrosis in tight skin 1 mice
    M Hansson
    Department of Immunology, The Wenner Gren Institute, Arrhenius Laboratories for the Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 59:469-77. 2004
    ..Thus, exposure to mercury accelerates the immune dysregulation, but not the development of skin fibrosis in Tsk1/+ mice...
  6. doi request reprint Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?
    B Sadeghi
    Experimental Cancer Medicine, Institution for Laboratory Medicine, Karolinska Institute, Stockholm, Sweden
    Bone Marrow Transplant 48:284-93. 2013
    ..Moreover, gene expression profile and histopathological findings in the kidney are similar to those observed in the liver of GVHD mice...
  7. pmc Xenobiotic metal-induced autoimmunity: mercury and silver differentially induce antinucleolar autoantibody production in susceptible H-2s, H-2q and H-2f mice
    M Hansson
    Department of Immunology, The Wenner Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 131:405-14. 2003
    ..Our findings also suggest that the ability of a xenobiotic metal merely to create cryptic self-peptides may not be sufficient for the induction of an ANolA response...
  8. doi request reprint Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion
    S al Hashmi
    Experimental Cancer Medicine ECM, Department for Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden
    Bone Marrow Transplant 48:843-8. 2013
    ..We conclude that food supplements should be considered in patients undergoing BMT and/or chemotherapy treatment...
  9. ncbi request reprint Spontaneous downregulation of antibody/autoantibody synthesis in susceptible mice upon chronic exposure to mercuric chloride is not owing to a general immunosuppression
    S Roether
    Department of Immunology, The Wenner Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 55:493-502. 2002
    ..Our findings show that the autoregulation of mercury-induced immune/autoimmune responses observed after chronic treatment with mercury is not owing to a general immunosuppression...
  10. ncbi request reprint Genetic control of resistance to mercury-induced immune/autoimmune activation
    M Abedi-Valugerdi
    Department of Immunology, The Wenner-Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 54:190-7. 2001
    ..Thus, while in DBA/2 mice, gene(s) in the H-2 loci strictly contribute to the inheritance of resistance to ANolA production; non-H-2 genes mainly govern the inheritance of unresponsiveness regarding other characteristics...
  11. ncbi request reprint Immune complex-induced chronic and intense IL-4 independent IgG1-rheumatoid factor production in NZB mice
    E Nordstrom
    Department of Immunology, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 53:32-9. 2001
    ..It was, however, found that the cross-reactivity with IgG of human, goat and rabbit origin did not change between the two time points...
  12. doi request reprint Characterization of the hepatic and splenic immune status and immunoglobulin synthesis in aged male mice lacking the peroxisome proliferator-activated receptor-alpha (PPARĪ±)
    M R Qazi
    Department of Biochemistry and Biophysics, Arrhenius Laboratories for the Natural Sciences, Stockholm University, Stockholm, Sweden
    Scand J Immunol 73:198-207. 2011
    ..Thus, our findings indicate that upon ageing, PPARĪ± plays a crucial role in regulating the total numbers, compositions and functions of immune cells in both lymphoid and non-lymphoid immune organs of mice...
  13. doi request reprint The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model
    B Sadeghi
    Experimental Cancer Medicine, Department of Laboratory Medicine, Karolinska Institutet and Clinical Research Center Novum, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Bone Marrow Transplant 41:895-904. 2008
    ....
  14. pmc Isolation of murine intrahepatic immune cells employing a modified procedure for mechanical disruption and functional characterization of the B, T and natural killer T cells obtained
    K G Blom
    Department of Biochemistry and Biophysics, Arrhenius Laboratories for the Natural Sciences, Stockholm University, Stockholm, Sweden
    Clin Exp Immunol 155:320-9. 2009
    ..Thus, the simple procedure for the mechanical disruption of mouse liver described here results in more efficient isolation of functionally competent IHIC for various types of investigation...
  15. pmc Analysis of mercury-induced immune activation in nonobese diabetic (NOD) mice
    N Brenden
    Hagedorn Research Institute, Gentofte, Denmark
    Clin Exp Immunol 125:202-10. 2001
    ..Thus, mercury-induced immune activation can counter-regulate the Th1 cell-mediated autoimmune responses and confer a partial protection against autoimmune diabetes in NOD mice...