Birgitta Stegmayr

..The WHO initiated, 20 years ago, the MONICA Project. The aim of the study was to measure trends in coronary heart disease and stroke and to assess the extent to which these were related to changes in known risk factors...

..In most MONICA populations, the study has covered a period of 10 years or more...

..The aim of this prospective study was to determine if iron status and HFE genotypes constitute risk factors for stroke...

..Our data indicate that telomere length is associated with an "obesity-phenotype" but only in women...

..To investigate whether subjects with daytime sleepiness who snore or report witnessed sleep apneas drive more than others...

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..The authors describe the occurrence of diabetes and obesity in the population of Northern Sweden and the role of diabetes in cardiovascular disease...

..To compare the levels of the main cardiovascular risk factors in communities of different sizes in northern Sweden...

..Leptin, an important hormone for body weight regulation, may be involved in the pathogenesis of cardiovascular manifestations of obesity. We tested whether leptin may be an independent risk marker for stroke in a case-referent study...

..We studied how heparin treatment for progressive stroke has been discarded in Sweden...

..The development and maintenance of this sustainable national register is described...

..Thus, acute and early mortality inflict prognosis on long-term outcome. In order to give a more robust analysis of long-term survival after the acute period we chose to start our observation with 3-month survivors...

..Using a candidate region approach, we wanted to test the validity of these findings in a different population from northern Sweden...

..Secondly, some examples are given of studies on cardiovascular disease and diabetes with a focus on the biomarker programme. The cohort has been positioned as a national and international resource for scientific research...

..The purpose of this study was to explore whether the use of snuff, a smokeless tobacco product, increases the risk of stroke in men...

..For several aspects, eg, comparisons between outcome in clinical studies and observational studies, we determined to see whether the functional outcome, as assessed in a quality register, can be transformed into mRS grades...

..2% (CI 1.4-3.4%) by 2004. For the first time snus use is also associated with a decrease in smoking prevalence among women. These patterns of tobacco use have implications for all smoking-dominated societies...

..The study examines trends in food and nutrient intake, serum cholesterol and body mass index (BMI) from 1986 to 2010 in northern Sweden...

..Riks-Stroke, the Swedish national quality register on stroke care, provides unique opportunities to evaluate stroke units in routine clinical care...

..We aimed to analyze the relationship between snoring, witnessed sleep apnea and diabetes mellitus and to analyze possible gender related differences in an unselected population...

..Fatigue is common among stroke patients. This study determined the prevalence of fatigue among long-term survivors after stroke and what impact fatigue had on various aspects of daily life and on survival...

..92; 95% CI, 1.33-6.39; P = 0.007). Our results indicate that blood RTL may serve as a prognostic indicator in breast cancer patients with advanced disease...

..To explore the stability of sense of coherence (SOC) over time in a normal population and to examine its relation to gender and psychosocial factors...

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..A multivariate partial least square analysis showed that poorer health, pain, and adverse aspects of emotional support and social networks contributed significantly to the pattern of poor sleep...

..We found no significant differences concerning BMI, marital status, educational level, smoking habits, psychosocial work situation on the Karasek questionnaire or physical activity during leisure time or at work...

..Therefore, it is very important to reduce or eliminate risk factors for stroke. Preventing a stroke saves much suffering for both patients and relatives and reduces the economic burden for the society...

..To examine how self-rated ill-health interacts with biomedical stroke risk factors in predicting stroke and to explore differences between men and women and educational groups...

..In this study, trends in incidence, 28-day case fatality (CF), and mortality in SAH were followed over a 16-year period...

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..This study analyzed the potential association between shift work and ischemic stroke...

..The objective of this study was to verify and explain differences between men and women in management and outcome after stroke in a national perspective...

..Obesity, especially abdominal, is a risk factor for many diseases. This study explored trends in the prevalence of general and abdominal obesity, 1986-2004, in northern Sweden...

..Polymorphisms in involved genes have been described and implicated in stroke. The aim of this study was to investigate two polymorphisms in two genes in the renin-angiotensin system and the risk of stroke...

..Risk equations estimated by statistical methods are another way of predicting cardiovascular risk...

..The implication of this finding for national prevention strategies should be vigorously explored...

..3%) wanted to be informed and give their concent to every new specific project. All the others gave a general concent provided that an Ethics Committee had approved the research...

..18; CI, 0.05 to 0.69). No significant association was found for VWF. We suggest that the novel finding of an inverse relation between sTM and hemorrhagic stroke should be investigated in a larger study...

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..Low treatment and control rates in Europe, combined with a higher prevalence of hypertension, could contribute to a higher burden of cardiovascular disease risk attributable to elevated blood pressure compared with that in North America...

..Depressive mood after a cardiac event is common with serious consequences for the patient...

..Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. Materials and..

..However, understanding what determines an individual's dietary preferences and how to change his/her behavior remains limited. The aim of the present study was to evaluate associations between dietary intake and SOC in adults...

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..No clear time trends were found in physical activity or in the use of tobacco...

..The aim of this study was to investigate the common functional 4/5 guanosine (4G/5G) polymorphism in the promoter region of the PAI-1 gene and the risk of stroke...

..In the subsequent surveys, the quality of cholesterol data was good. CONCLUSIONS: Great effort was put in to ensure good data quality and Northern Sweden is one of the MONICA units with very good quality of data...

..To further improve the health status in Sweden, it is important to decrease the pollution of Cd, and actions against smoking in the community are important...

..Thirty percent could stay alone less than half a day. These results will be used for improving rehabilitation for the stroke patients and support for their spouses...

..To examine the incidence and outcome of acute myocardial infarction (AMI) in patients with rheumatoid arthritis compared with the general population, and to examine whether care and treatment of an AMI differs between patients and controls...

..Taking advantage of low genetic variations in northern Sweden, we performed a genome-wide linkage scan to investigate the susceptibility loci for common forms of stroke...

..Increased levels of EPA and DHA do not decrease the risk for stroke and there is no association between stroke risk and Hg at these low levels...

..The aims of this study were to describe gender differences in patients with burnout and compare these patients with a general population with respect to physical, psychosocial and work variables...