Roland Rosmond

Summary

Affiliation: Sahlgrenska University Hospital
Country: Sweden

Publications

  1. ncbi request reprint Polymorphism in exon 4 of the human 3 beta-hydroxysteroid dehydrogenase type I gene (HSD3B1) and blood pressure
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Biochem Biophys Res Commun 293:629-32. 2002
  2. ncbi request reprint 5-HT2A receptor gene promoter polymorphism in relation to abdominal obesity and cortisol
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Obes Res 10:585-9. 2002
  3. ncbi request reprint The CYP19 gene and associations with androgens and abdominal obesity in premenopausal women
    Fariba Baghaei
    The Cardiovascular Institute, Sahlgrenska University Hospital, Goteborg, Sweden
    Obes Res 11:578-85. 2003
  4. ncbi request reprint Increased abdominal obesity, insulin and glucose levels in nondiabetic subjects with a T29C polymorphism of the transforming growth factor-beta1 gene
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Horm Res 59:191-4. 2003
  5. ncbi request reprint Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Biochim Biophys Acta 1588:103-5. 2002
  6. doi request reprint A 5-year follow-up study of 3 polymorphisms in the human glucocorticoid receptor gene in relation to obesity, hypertension, and diabetes
    Roland Rosmond
    Cardiovascular Institute, Sahlgrenska University Hospital, Goteborg, Sweden
    J Cardiometab Syndr 3:132-5. 2008
  7. ncbi request reprint Dyslipidemia and high waist-hip ratio in women with self-reported social anxiety
    Mikael Landen
    Department of Psychiatry, Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg University, SE 431 80 Molndal, Sweden
    Psychoneuroendocrinology 29:1037-46. 2004
  8. ncbi request reprint The Pro12Ala PPARgamma2 gene missense mutation is associated with obesity and insulin resistance in Swedish middle-aged men
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Diabetes Metab Res Rev 19:159-63. 2003
  9. ncbi request reprint Polymorphisms in exon 3 of the proopiomelanocortin gene in relation to serum leptin, salivary cortisol, and obesity in Swedish men
    Roland Rosmond
    Department of Internal Medicine, Research Centre for Endocrinology and Metabolism, Goteborg University, Grona Straket 8, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Metabolism 51:642-4. 2002
  10. doi request reprint Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men
    Kristina Annerbrink
    Institute of Neuroscience and Physiology, Goteborg University, and Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, S 405 30 Goteborg, Sweden
    Metabolism 57:708-11. 2008

Detail Information

Publications22

  1. ncbi request reprint Polymorphism in exon 4 of the human 3 beta-hydroxysteroid dehydrogenase type I gene (HSD3B1) and blood pressure
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Biochem Biophys Res Commun 293:629-32. 2002
    ..The pathogenic mechanism underlying this association is, however, uncertain from the present data and further studies are warranted...
  2. ncbi request reprint 5-HT2A receptor gene promoter polymorphism in relation to abdominal obesity and cortisol
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Obes Res 10:585-9. 2002
    ....
  3. ncbi request reprint The CYP19 gene and associations with androgens and abdominal obesity in premenopausal women
    Fariba Baghaei
    The Cardiovascular Institute, Sahlgrenska University Hospital, Goteborg, Sweden
    Obes Res 11:578-85. 2003
    ..Polymorphisms of a tetranucleotide repeat [TTTA](n) in the fourth intron of the CYP19 gene are associated with endocrine-dependent diseases and were examined in relation to hormone levels and disease risk factors in premenopausal women...
  4. ncbi request reprint Increased abdominal obesity, insulin and glucose levels in nondiabetic subjects with a T29C polymorphism of the transforming growth factor-beta1 gene
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Horm Res 59:191-4. 2003
    ....
  5. ncbi request reprint Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Biochim Biophys Acta 1588:103-5. 2002
    ..From these data, we conclude that the C-->T substitution in exon 4 of the UCP2 gene does not contribute to the predisposition to be affected by the Metabolic Syndrome...
  6. doi request reprint A 5-year follow-up study of 3 polymorphisms in the human glucocorticoid receptor gene in relation to obesity, hypertension, and diabetes
    Roland Rosmond
    Cardiovascular Institute, Sahlgrenska University Hospital, Goteborg, Sweden
    J Cardiometab Syndr 3:132-5. 2008
    ..It is concluded that the genetic information about GRL would be useful for further genetic study of obesity, diabetes, and related metabolic diseases...
  7. ncbi request reprint Dyslipidemia and high waist-hip ratio in women with self-reported social anxiety
    Mikael Landen
    Department of Psychiatry, Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Goteborg University, SE 431 80 Molndal, Sweden
    Psychoneuroendocrinology 29:1037-46. 2004
    ..83+/-0.06 vs. 0.80+/-0.07, P=0.016), BMI did not differ between the groups. Our data suggest that self-reported social anxiety is associated with two established risk factors for cardiovascular disease: dyslipidemia and increased WHR...
  8. ncbi request reprint The Pro12Ala PPARgamma2 gene missense mutation is associated with obesity and insulin resistance in Swedish middle-aged men
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Diabetes Metab Res Rev 19:159-63. 2003
    ..The Pro12Ala PPARgamma2 polymorphism has been variably associated with obesity, insulin sensitivity, and dyslipidemia...
  9. ncbi request reprint Polymorphisms in exon 3 of the proopiomelanocortin gene in relation to serum leptin, salivary cortisol, and obesity in Swedish men
    Roland Rosmond
    Department of Internal Medicine, Research Centre for Endocrinology and Metabolism, Goteborg University, Grona Straket 8, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Metabolism 51:642-4. 2002
    ..This association might reflect variations in melanocortin expression and/or activity, because exon 3 contains, among others, the coding sequences for melanocortins...
  10. doi request reprint Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men
    Kristina Annerbrink
    Institute of Neuroscience and Physiology, Goteborg University, and Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, S 405 30 Goteborg, Sweden
    Metabolism 57:708-11. 2008
    ....
  11. ncbi request reprint Increased abdominal obesity in subjects with a mutation in the 5-HT(2A) receptor gene promoter
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Ann N Y Acad Sci 967:571-5. 2002
    ..The pathophysiology could involve stress factors that destabilize the serotonin-hypothalamic-pituitary-adrenal systems in those with genetic vulnerability in the serotonin receptor gene...
  12. ncbi request reprint Association between a variant at the GABA(A)alpha6 receptor subunit gene, abdominal obesity, and cortisol secretion
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Ann N Y Acad Sci 967:566-70. 2002
    ..The pathophysiology may involve various environmental factors, particularly stress, that destabilize the GABA-hypothalamic-pituitary-adrenal systems in those with genetic vulnerability...
  13. ncbi request reprint A brief update of glucocorticoid receptor variants and obesity risk
    Roland Rosmond
    The Cardiovascular Institute, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
    Ann N Y Acad Sci 1083:153-64. 2006
    ..In this article, we will estimate the risk by which such gene polymorphism mediates a role in obesity...
  14. ncbi request reprint Depression and anxiety symptoms in relation to anthropometry and metabolism in men
    Ann Charlotte Ahlberg
    Department of Psychiatry, Sahlgrenska University Hospital, University of Goteborg, Sweden
    Psychiatry Res 112:101-10. 2002
    ..We conclude that men with abdominal obesity have symptoms of depression and anxiety...
  15. ncbi request reprint Stress induced disturbances of the HPA axis: a pathway to Type 2 diabetes?
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Med Sci Monit 9:RA35-9. 2003
    ..The HPA axis perturbations associated with visceral obesity can be accounted for, in part, by increased environmental stress that destabilizes the hypothalamic-pituitary system in individuals with genetic susceptibility...
  16. ncbi request reprint The glucocorticoid receptor gene and its association to metabolic syndrome
    Roland Rosmond
    Department of Clinical Chemistry, Sahlgrenska University Hospital, Goteborg, Sweden
    Obes Res 10:1078-86. 2002
    ..Further studies focusing on the most compelling GR mutations might offer a better understanding of metabolic syndrome pathogenesis and progression, aiding in the development of more effective treatments for this condition...
  17. ncbi request reprint Interleukin-6 gene polymorphism -174G/C influences plasma lipid levels in women
    Susanne Henningsson
    Department of Pharmacology, The Sahlgrenska Academy at Goteborg University, Box 431, SE 405 30 Goteborg, Sweden
    Obesity (Silver Spring) 14:1868-73. 2006
    ..None of the associations between IL-6 genotype and lipid pattern seemed to result from an effect of the polymorphism on IL-6 plasma levels...
  18. ncbi request reprint Angiotensin-related genes in patients with panic disorder
    Marie Olsson
    Department of Pharmacology, Goteborg University, Gothenburg, Sweden
    Am J Med Genet B Neuropsychiatr Genet 127:81-4. 2004
    ..005), but not female, panic disorder patients than in controls. The results of this investigation provide preliminary evidence for the suggestion that angiotensin-related genes may be associated with panic disorder in men...
  19. ncbi request reprint A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women
    Jonas Melke
    Departments of Pharmacology, Goteborg University, Goteborg, Sweden
    Arch Gen Psychiatry 60:1017-23. 2003
    ..A polymorphism (C178T) in the 5' region of the HTR3A gene has recently been identified and suggested to be of functional importance...
  20. ncbi request reprint Polymorphisms in oestrogen and progesterone receptor genes: possible influence on prolactin levels in women
    Lars Westberg
    Department of Pharmacology, Goteborg University, Goteborg, Sweden
    Clin Endocrinol (Oxf) 61:216-23. 2004
    ....
  21. ncbi request reprint Sex steroid-related genes and male-to-female transsexualism
    Susanne Henningsson
    Department of Pharmacology, Institute of Physiology and Pharmacology, Goteborg University, Goteborg, Sweden
    Psychoneuroendocrinology 30:657-64. 2005
    ..Further study of the putative role of these and other sex steroid-related genes for the development of transsexualism may, however, be worthwhile...
  22. ncbi request reprint The lean woman
    Fariba Baghaei
    Department of Heart and Lung Diseases, University of Goteborg, Goteborg, Sweden
    Obes Res 10:115-21. 2002
    ..In the current obesity epidemic, the ability to remain lean is beginning to be uncommon. Therefore, it was considered of interest to characterize such subjects...