Affiliation: Sahlgrenska University Hospital
Rizell M, Mattson J, Cahlin C, Hafström L, Lindner P, Olausson M. Isolated hepatic perfusion for liver metastases of malignant melanoma. Melanoma Res. 2008;18:120-6 pubmed publisher
..The maximum tolerated dose for melphalan in the perfusate was surpassed with a 2 mg/kg body weight. By modifying the technique and restricting the allowed tumor burden, the response rate remained high and the mortality was reduced. ..
HÃ¶gberg J, Rizell M, Hultborn R, Svensson J, Henrikson O, MÃ¶lne J, et al
. Increased absorbed liver dose in Selective Internal Radiation Therapy (SIRT) correlates with increased sphere-cluster frequency and absorbed dose inhomogeneity. EJNMMI Phys. 2015;2:10 pubmed publisher
..Sphere clusters were located in both arterioles and small arteries and increased in size with increasing sphere concentration, resulting in increased absorbed dose inhomogeneity, which contradicts earlier modelling studies. ..
Rizell M, Lindner P. Inhibition of mTOR suppresses experimental liver tumours. Anticancer Res. 2005;25:789-93 pubmed
..01). The three tumours studied, an nitrosoguanidin-induced adenocarcinoma, a Leydig cell sarcoma and a hepatoma, all responded, establishing sirolimus as a promising anticancer drug. ..
Schnitzbauer A, Zuelke C, Graeb C, Rochon J, Bilbao I, Burra P, et al
. A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma. BMC Cancer. 2010;10:190 pubmed publisher
..A positive outcome will likely change the standard of posttransplant immunosuppressive care for LT patients with HCC. Trial registered at http://www.clinicaltrials.gov: NCT00355862(EudraCT Number: 2005-005362-36). ..
Rizell M, Hellstrand K, Lindner P, Naredi P. Monotherapy with histamine dihydrochloride suppresses in vivo growth of a rat sarcoma in liver and subcutis. Anticancer Res. 2002;22:1943-8 pubmed