Research Topics
Genomes and Genes | C LarssonSummaryAffiliation: Sahlgrenska University Hospital Country: Sweden Publications
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Detail Information
Publications
Association between low concentrations of antibodies to protein alpha and Rib and invasive neonatal group B streptococcal infectionC Larsson
Department of Medical Microbiology, Lund University, Lund, Sweden
Arch Dis Child Fetal Neonatal Ed 91:F403-8. 2006..The GBS cell surface proteins alpha and Rib elicit protective immunity in animal models and have been suggested as potential antigens in a vaccine against human GBS disease...
Cross-protection between group A and group B streptococci due to cross-reacting surface proteinsM Stålhammar-Carlemalm
Department of Laboratory Medicine, Lund University, S 22362 Lund, Sweden
J Infect Dis 182:142-9. 2000..Analysis of these data suggests that cross-protection may influence the outcome of natural infections with R28-expressing GAS and Rib-expressing GBS...
A PKCbeta isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cellsU Trollér
Lund University, Molecular Medicine, Malmo University Hospital, 205 02 Malmo, Sweden
FEBS Lett 508:126-30. 2001..These data indicate that activation of a PKCbeta isoform, through a pathway involving Erk1/2, leads to increased expression of neuronal differentiation genes in neuroblastoma cells...
The 14-3-3 protein interacts directly with the C-terminal region of the plant plasma membrane H(+)-ATPaseT Jahn
Department of Plant Biochemistry, Lund University, Sweden
Plant Cell 9:1805-14. 1997..We propose that the 14-3-3 protein is a natural ligand of the plasma membrane H(+)-ATPase, regulating proton pumping by displacing the C-terminal autoinhibitory domain of the H(+)-ATPase...
Evolution of the 14-3-3 protein family: does the large number of isoforms in multicellular organisms reflect functional specificity?M Rosenquist
Department of Plant Biochemistry, Lund University, P O Box 117, SE 221 00 Lund, Sweden
J Mol Evol 51:446-58. 2000..Thus, our data suggest that one reason for the large number of isoforms found in multicellular organisms is isoform-specific functions...
A phosphothreonine residue at the C-terminal end of the plasma membrane H+-ATPase is protected by fusicoccin-induced 14-3-3 bindingA Olsson
Department of Plant Biochemistry, Lund University, P O Box 117, SE 221 00 Lund, Sweden
Plant Physiol 118:551-5. 1998..This is the first identification to our knowledge of an in vivo phosphorylation site in the plant plasma membrane H+-ATPase...
The R28 protein of Streptococcus pyogenes is related to several group B streptococcal surface proteins, confers protective immunity and promotes binding to human epithelial cellsM Stålhammar-Carlemalm
Department of Laboratory Medicine, Lund University, Solvegatan 23, 22362 Lund, Sweden
Mol Microbiol 33:208-19. 1999..We consider the hypothesis that R28 played a pathogenetic role in the well-known epidemics of childbed fever (puerperal fever), which were caused by S. pyogenes. A role for R28 in these epidemics is suggested by epidemiological data...
The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cellsC K Thodeti
Division of Experimental Pathology, Lund University, U-MAS, , SE-205 02, Sweden
Exp Cell Res 262:95-103. 2001..These data suggest that PKCepsilon plays a unique role in regulation of the LTD(4)-dependent Ca(2+) signal in intestinal epithelial cells...
Data mining the Arabidopsis genome reveals fifteen 14-3-3 genes. Expression is demonstrated for two out of five novel genesM Rosenquist
Department of Plant Biochemistry, Lund University, P O Box 117, SE 221 00 Lund, Sweden
Plant Physiol 127:142-9. 2001..In total, there are 15 14-3-3 genes (grfs 1-15) in Arabidopsis, of which 12 (grfs 1-12) now have been shown to be expressed...
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear BaxJ Karlsson
Department of Laboratory Medicine, Division of Molecular Medicine, University Hospital MAS, Lund University, Malmo, Sweden
Oncogene 26:6150-9. 2007..This model is strengthened by the observation that calpain, the protease responsible for p18 Bax generation, is present in the nuclei, and that nuclear calpain is induced by increasing As(2)O(3) and Ca(2+) levels...
Differences in early and late responses between neurotrophin-stimulated trkA- and trkC-transfected SH-SY5Y neuroblastoma cellsA Edsjö
Department of Laboratory Medicine, Lund University, University Hospital MAS, Malmo, Sweden
Cell Growth Differ 12:39-50. 2001..Our data suggest that NT-3/p145trkC and NGF/p140trkA signaling differ in some aspects in neuroblasoma cells, and that this may explain the phenotypic differences seen in the long-term neurotrophin-treated cells...
The regulatory domain of protein kinase Ctheta localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cellsA Schultz
Lund University, Molecular Medicine, Entrance 78, 3rd Floor, UMAS, 205 02 Malm, Sweden
Cell Death Differ 10:662-75. 2003..This suggests that the PKCtheta RD has apoptotic activity and that Golgi localisation may be important for this effect...
A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouseJ Lagercrantz
Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden
Biochim Biophys Acta 1398:157-63. 1998..There are at present at least three specific effectors of vascular proliferation with clear differences in their expression...
Expression of the BCL6 gene in the pre- and postnatal mouseS Bajalica-Lagercrantz
Department of Molecular Medicine, CMM L8 01, Karolinska Hospital, Stockholm, Sweden
Biochem Biophys Res Commun 247:357-60. 1998..Thus, bcl6 may be active as a regulator of gene transcription in many different cell types, including epithelial and nerve cells...
The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocationC Larsson
Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden
Genomics 24:253-8. 1994..2-p13.1, respectively, which are regions of neoplasia-associated translocation...
