Research Topics
| C HansonSummaryAffiliation: Sahlgrenska University Hospital Country: Sweden Publications
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Detail Information
Publications
Sensitivity to extrinsically supplied interferon and the endogenous expression of interferon in melanoma cell linesC Hanson
Department of Oncology, Sahlgrenska University Hospital, Goteborg, Sweden
Melanoma Res 9:451-6. 1999..We hypothesize that tumours with enhanced endogenous IFN production may respond more positively to IFN treatment...
Personality traits in women with Turner syndromeUlla Wide Boman
International Pediatric Growth Research Center at the Department of Pediatrics, Goteborg University, Sweden
Scand J Psychol 47:219-23. 2006..Contrary to some previous findings, no differences in personality were found between the karyotype groups...
Transplantation of human embryonic stem cells onto a partially wounded human cornea in vitroCharles Hanson
Unit of Clinical Sciences, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, University of Gothenburg, Goteborg, Sweden
Acta Ophthalmol 91:127-30. 2013..A second aim was to study the ability of the transplanted cells to differentiate into corneal epithelial-like cells...
Re-analysis of 166 embryos not transferred after PGS with advanced reproductive maternal age as indicationC Hanson
Unit of Reproductive Medicine, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden
Hum Reprod 24:2960-4. 2009..The aim of this study was to determine how well the chromosomal constitution of one biopsied blastomere reflects the status of the entire embryo...
Human embryonic stem cells and chromosome stabilityCharles Hanson
Department of Obstetrics and Gynecology, Goteborg University, Sahlgrenska University Hospital, Goteborg, Sweden
APMIS 113:751-5. 2005..We also recommend freezing of HESC at low passage number and in larger batches after thawing and expansion in order to secure material in case mutations occur in the cell line at a later stage of culture...
Preimplantation genetic screening in women of advanced maternal age caused a decrease in clinical pregnancy rate: a randomized controlled trialT Hardarson
Fertility Centre Scandinavia, Carlanderska Hospital, Goteborg, Sweden
Hum Reprod 23:2806-12. 2008..The purpose of this study was to test whether employing preimplantation genetic screening (PGS) in AMA patients would increase the clinical pregnancy rate...
Obstetric outcomes in women with Turner karyotypeA Hagman
Institution of Clinical Sciences, Department of Medicine, Sahlgrenska University Hospital, Sahlgrenska Academy at University of Gothenburg, S 416 85 Gothenburg, Sweden
J Clin Endocrinol Metab 96:3475-82. 2011..Women with Turner syndrome (TS) have high risk of cardiovascular complications and hypertensive disorders. Few studies have analyzed obstetric outcome in women with TS...
Prevalence of Klinefelter's syndrome in male breast cancer patientsR Hultborn
Department of Oncology, Sahlgrenska University Hospital, Goteborg, Sweden
Anticancer Res 17:4293-7. 1997..The same median age at diagnosis, 72 years, was established for both groups of patients. No differences in survival were seen...
Human embryos with unevenly sized blastomeres have lower pregnancy and implantation rates: indications for aneuploidy and multinucleationT Hardarson
Department of Obstetrics and Gynaecology, , SU/Sahlgrenska, 413 45 Gothenburg, Sweden
Hum Reprod 16:313-8. 2001..In the light of the results obtained, a new approach in the current embryo scoring system, placing more emphasis on blastomere size, is recommended...
The influence of karyotype on the auricle, otitis media and hearing in Turner syndromeM L Barrenas
Department of Audiology, Sahlgrenska University Hospital, Goteborg University, S 413 45, Goteborg, Sweden
Hear Res 138:163-70. 1999..It is suggested that karyotype may be used as a predictor for future ear and hearing problems in TS...
Chromosomal integrity maintained in five human embryonic stem cell lines after prolonged in vitro cultureGunilla Caisander
Cellartis AB, Arvid Wallgrens Backe 20, SE-413 46, , Sweden
Chromosome Res 14:131-7. 2006..We discuss the most common de novo chromosomal aberrations reported in hESCs, as well as their possible origin...
Preimplantation genetic diagnosis (PGD): the Gothenburg experienceC Hanson
Department of Obstetrics and Gynecology, Sahlgrenska University Hospital and Fertilitetscentrum, , Sweden
Acta Obstet Gynecol Scand 80:331-6. 2001..Taking into account the stress caused to the parents facing late interruption of pregnancy following conventional prenatal diagnosis we are convinced that this technique is well worthwhile continuing and refining...
Testicular ultrasonography and extended chromosome analysis in men with nonmosaic Klinefelter syndrome: a prospective study of possible predictive factors for successful sperm recoveryG Westlander
Center for Reproductive Medicine, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden
Fertil Steril 75:1102-5. 2001....
A study of 45,X/46,XX mosaicism in Turner syndrome females: a novel primer pair for the (CAG)n repeat within the androgen receptor geneJ Leonova
Centre of Reproductive Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
Hereditas 131:87-92. 1999..A high sensitivity of the modified assay based on PCR-amplification of the (CAG)n repeat within AR gene proves its usefulness as a tool for studying mosaicism in Turner syndrome...
A morphological and chromosomal study of blastocysts developing from morphologically suboptimal human pre-embryos compared with control blastocystsThorir Hardarson
Department of Obstetrics and Gynaecology, Goteborg University, SU Sahlgrenska, 413 45 Gothenburg, Sweden
Hum Reprod 18:399-407. 2003..As a control group we used morphologically good quality embryos (GQE), cultured to the blastocyst stage...
A human oocyte with two sets of MII/PB-structuresThorir Hardarson
Department of Obstetrics and Gynaecology, Goteborg University, SU Sahlgrenska, 13 45 Gothenburg, Sweden
Hum Reprod 17:1892-4. 2002..We speculate that this duplication may be caused by oocyte fusion at an early stage...
Ear and hearing in relation to genotype and growth in Turner syndromeM Barrenas
Department of Audiology, Sahlgrenska University Hospital, Goteborg, University, Sweden
Hear Res 144:21-8. 2000..A new hypothesis on the pathophysiology of external, middle and inner ear disorders due to a delayed cell cycle caused by chromosomal aberrations per se and not only to the specific X chromosome deletion is presented...
Genetic analysis of mosaicism in 53 women with Turner syndromeL Hanson
Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Gothenburg, Sweden
Hereditas 134:153-9. 2001..Based on these results, we suggest the use of X/Y interphase FISH as a complement to karyotyping in order to obtain a more complete knowledge of the chromosome constitution of each individual with TS...
Derivation, characterization, and differentiation of human embryonic stem cellsNico Heins
Cellartis AB, , Sweden
Stem Cells 22:367-76. 2004..Furthermore, we clonally derived one cell line, which could be propagated in an undifferentiated pluripotent state...
Chromosomal mosaicism mitigates stigmata and cardiovascular risk factors in Turner syndromeMostafa El Mansoury
Department of Internal Medicine, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
Clin Endocrinol (Oxf) 66:744-51. 2007..To study genotype-phenotype correlations in Turner syndrome (TS) regarding body composition, cardiovascular risk factors, stigmata and age at diagnosis vs. degree of mosaicism estimated as the percentage of 45,X and 46,XX cells...
Hypothyroidism is common in turner syndrome: results of a five-year follow-upMostafa El-Mansoury
Endocrine Division, Sahlgrenska University Hospital, , Sweden
J Clin Endocrinol Metab 90:2131-5. 2005..Altogether, 34 (37%) TS women had hypothyroidism after the 5-yr follow-up. Autoimmune hypothyroidism was common, with an annual incidence of 3.2% in TS. Thyroid function should be checked regularly in TS...
Fluorescence in situ hybridisation analysis and ovarian histology of women with Turner syndrome presenting with Y-chromosomal material: a correlation between oral epithelial cells, lymphocytes and ovarian tissueLars Hanson
Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, , Sweden
Hereditas 137:1-6. 2002..We therefore conclude that FISH analysis of oral epithelial cells and/or lymphocytes is a valuable complement to karyotyping for the early detection of Y-chromosomal material in TS women...
Donor-derived myofibroblasts in the ocular surface after allogeneic haematopoietic stem cell transplantationDavid Hallberg
Department of Ophthalmology, , Gothenburg, Sweden
Acta Ophthalmol Scand 84:774-80. 2006..Whether myofibroblasts are implicated in ocular graft-versus-host disease requires further studies...
Longterm survival of transplanted human corneal epithelial cells and corneal stem cellsMaria Egarth
Institute of Clinical Neurosciences, Section of Ophthalmology, Sahlgren University Hospital, , Sweden
Acta Ophthalmol Scand 83:456-61. 2005..In combined stem cell and corneal grafts (HPCLK), donor-derived epithelial cells may also be retrieved at 1 year or beyond following surgery but the correlation between their presence and a remaining clear graft is uncertain...
Myofibroblasts in the normal ocular surfaceXimena Aguilar
Acta Ophthalmol 86:347-8. 2008
Longterm survival of transplanted human corneal epithelial cells and corneal stem cellsMaria Egarth
Institute of Clinical Neurosciences, Section of Ophthalmology, Sahlgren University Hospital, , Sweden
Acta Ophthalmol Scand 83:456-61. 2005..In combined stem cell and corneal grafts (HPCLK), donor-derived epithelial cells may also be retrieved at 1 year or beyond following surgery but the correlation between their presence and a remaining clear graft is uncertain...
Survival of transplanted human corneal stem cells. Case reportUlf Stenevi
Department of Ophthalmology, Sahlgren University Hospital, Molndal, Sweden
Acta Ophthalmol Scand 80:105-8. 2002..To report a case history involving long-term survival of transplanted human corneal stem cells...
Clonal derivation and characterization of human embryonic stem cell linesNico Heins
Cellartis AB, Arvid Wallgrens Backe 20, , Sweden
J Biotechnol 122:511-20. 2006..In addition, the combination of the parental trisomic hESC line SA002 and the diploid subclone SA002.5 provides a unique experimental system to study the molecular mechanisms underlying the pathologies associated with trisomy 13...
