Research Topics
| Styrbjorn FrimanSummaryAffiliation: Sahlgrenska University Hospital Country: Sweden Publications
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Detail Information
Publications
Recurrence of disease after liver transplantationS Friman
Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden Electronic address
Transplant Proc 45:1178-81. 2013..This overview reports follow up, diagnosis, and treatment of recurrences...
Recurrence of hepatitis C after liver transplantationS Friman
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
Transplant Proc 37:3311-2. 2005..Today there is growing concern as to the prognosis of these patients and how we should treat them. This is an overview of the developments in this field concerning treatment of recurrence and the role of preemptive treatment...
Liver transplantation for cholangiocarcinoma: selection is essential for acceptable resultsStyrbjorn Friman
Transplant Institute, Sahlgrenska University Hospital, Goteborg, Sweden
Scand J Gastroenterol 46:370-5. 2011..The aim of this study has been to report our results as well as to explore factors that influence patient survival after liver transplantation for CCA...
Cholangiocarcinoma--current treatment optionsS Friman
Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden
Scand J Surg 100:30-4. 2011..The lack of effective medical treatment makes a radical surgical resection or hepatectomy the only therapeutic option. Most of the CCAs are unresectable at presentation and the prognosis for these patients is dismal...
Sotrastaurin, a novel small molecule inhibiting protein-kinase C: randomized phase II study in renal transplant recipientsS Friman
Transplant Institute, Sahlgrenska University Hospital, Goteborg, Sweden
Am J Transplant 11:1444-55. 2011..Ongoing studies are evaluating alternative sotrastaurin regimens...
Orthotopic liver or multivisceral transplantation as treatment of metastatic neuroendocrine tumorsMichael Olausson
Sahlgrenska Transplant Institute, Sahlgrenska Academy, University of Goteborg, Goteborg, Sweden
Liver Transpl 13:327-33. 2007..In conclusion, the critical prognosticators for long-term outcome still remain to be defined. The experience with multivisceral transplantation for patients with endocrine tumors of the pancreatic head is still limited...
Stable long-term renal function after pediatric liver transplantationGustaf Herlenius
Transplant Institute, Sahlgrenska University Hospital, Goteborg, Sweden
Pediatr Transplant 14:409-16. 2010..05). At one, three and five yr post-transplantation there was no longer a statistically significant difference between these cohorts. Our findings suggest that there can be a long-term recovery of renal function after LT in children...
Early renal function post-liver transplantation is predictive of progressive chronic kidney diseaseGustaf Herlenius
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Scand J Gastroenterol 43:344-9. 2008....
Chronic kidney disease--a common and serious complication after intestinal transplantationGustaf Herlenius
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transplantation 86:108-13. 2008..We describe long-term renal function after intestinal transplantation by serial measurements of glomerular filtration rates (GFR) with Chromium EDTA clearance...
Sympathetic nerves do not affect experimental ischemia-reperfusion injury of rat liverS Friman
Transplant Institute, Sahlgrenska University Hospital, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Transplant Proc 41:743-5. 2009..We investigated whether sympathetic, noradrenergic nerves participate in experimental acute ischemia-reperfusion injury of the rat liver...
[Treatment of patients with liver metastases from colorectal cancer. More patients can benefit from the treatment!]Per Lindner
Verksamhetsområde kirurgi och transplantation, Sahlgrenska Universitetssjukhuset, Goteborg
Lakartidningen 100:2684-8. 2003..A surgeon with liver surgery competence should see patients with a presumably resectable cancer...
[Liver dialysis using MARS in acute hepatic failure. Promising results in a pilot setting]Marie Felldin
Enheten för transplantation och leverkirurgi, Sahlgrenska Universitetssjukhuset, Goteborg
Lakartidningen 100:3836-8, 3841. 2003..In these cases the MARS-treatment seemed to have positive effects on the course and outcome of the disease but there are a need for controlled trials to clearly prove the benefit of the treatment...
Late mortality in 679 consecutive liver transplant recipients: the Gothenburg liver transplant experienceD J Lukes
Department of Surgery and Transplantation, Sahlgrenska University Hospital, Goteborg, Sweden
Transplant Proc 38:2671-2. 2006..We analyzed causes of late death (>/=2 years post-OLT) in 679 consecutive primary recipients in our institution...
Retransplantation of the liverB I Gustafsson
Transplantation and Liver Surgery Unit, Department of Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transplant Proc 38:1438-9. 2006..In summary, liver re-TX is a complicated procedure associated with significant mortality and morbidity, but considering that the actual patient group has a poor prognosis without re-TX, the results are nevertheless encouraging...
Extended right-sided liver resection for colorectal liver metastases--impact of percutaneous portal venous embolisationP Lindner
Department of Surgery and Radiology, Sahlgrenska University Hospital, S 413 45 Goteborg, Sweden
Eur J Surg Oncol 32:292-6. 2006..To compare the outcome after extended right liver lobe resection (ERL) for patients with liver metastases from colorectal cancer with preceding portal vein embolisation (PVE) with a non-PVE-group...
Nitric oxide-mediated effects on liver blood flowB I Gustafsson
Transplantation and Liver Surgery Unit, Dept of Surgery, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden
Transplant Proc 37:3338-9. 2005..Upon unclamping, there was no difference in ALT levels, PLBF, or MAP. To conclude, NO displayed a positive tonic effect on liver blood flow, reduction of which with l-NAME did not aggravate mild ischemia/reperfusion injury in this model...
Pharmacological preconditioning of rat liver by up-regulation of heme oxygenase 1J Heiman
Department of Surgery, Sahlgrenska University Hospital, , , Sweden
Transplant Proc 38:2705-7. 2006..CONCLUSION: Pretreatment with PDTC attenuated the disturbance of hepatic microcirculation, but not parenchymal injury, in the early phase of IRI...
Effect of remote preconditioning on mild or severe ischemia-reperfusion injury to rat liverB I Gustafsson
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transplant Proc 38:2708-9. 2006..Thus, a beneficial effect of RIPC was demonstrated in protocol I with relative hypoxemia to the liver. However, the effect could not be demonstrated in protocol II, which induced a more severe IR injury...
[Liver transplantation from a living donor is now possible. The first cases in Sweden completed with good results]M Olausson
Transplantation och leverkirurgi, Sahlgrenska Universitetssjukhuset, Goteborg
Lakartidningen 96:452-5. 1999..The technique will improve the outcome of liver transplantation in children, and reduce the risk of death due to long waiting lists...
Interventional treatment of gastrointestinal neuroendocrine tumoursH Ahlman
Department of Surgery, Radiology and Pathology at the Lundberg Laboratory for Cancer Research, Sahlgrenska University Hospital, Goteborg University, Sweden
Digestion 62:59-68. 2000..Such studies are hampered by the lack of strict surgical programs running over long periods and the relative rarity of NE tumours. Liver transplantation may be another treatment modality in selected cases...
Liver transplantation for polycystic liver disease--indications and outcomeB I Gustafsson
Transplantation and Liver Surgery Unit, Department of Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 35:813-4. 2003
The liver protective effect of ischemic preconditioning may be mediated by adenosineB Nilsson
Department of Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transpl Int 13:S558-61. 2000..This effect was abolished by pretreatment with 8-PT. Adenosine appears to be a crucial effector in IPC. Clinical studies need to be undertaken to explore a possible effect of IPC in liver transplantation...
Treatment with the molecular adsorbent recirculating system in patients with acute liver failureM Felldin
Transplantation and Liver Surgery Unit, , Sweden
Transplant Proc 35:822-3. 2003
Liver transplantation for metastatic neuroendocrine tumor diseaseC Cahlin
Transplantation and Liver Surgery Unit, Department of Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 35:809-10. 2003
Treatment of hepatitis C virus infection: updated Swedish Consensus recommendationsMartin Lagging
Department of Infectious Diseases and Virology, Sahlgrenska University Hospital, Goteborg
Scand J Infect Dis 41:389-402. 2009..For liver transplant patients pre-emptive therapy is not recommended; hence, treatment should be deferred until histological recurrence...
Preemptive therapy with pegylated interferon alpha-2b and ribavirin after liver transplantation for hepatitis C cirrhosisM Castedal
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 37:3313-4. 2005..CONCLUSION: In patients liver-transplanted due to HCV-cirrhosis, combination therapy with pegylated interferon and ribavirin can be effective and safe in the early posttransplant period, thus preventing recurrent hepatitis C...
Preconditioning protects against ischemia/reperfusion injury of the liverB Nilsson
Department of Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
J Gastrointest Surg 4:44-9. 2000..In our experimental model of ischemia/reperfusion injury in the rat liver, we found an equally beneficial effect with ischemic and pharmacologic preconditioning. Adenosine appears to be a crucial factor in IPC...
Combination therapy of interferon alpha-2B and ribavirin for recurrent hepatitis C after liver transplantationM Castedal
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 35:820-1. 2003
Adult ABO-incompatible liver transplantation, using A and B donorsUlrika Skogsberg
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Xenotransplantation 13:154-9. 2006..This applies in both urgent situations and for elective patients. We report on our experience with ABO-incompatible liver transplantation using A2 and B non-secretor donors here...
Survival after liver transplantation for cholangiocarcinoma has increased during the last decadeP Lindner
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transplant Proc 35:811-2. 2003
Calculation and comparison of the model for end-stage liver disease (MELD) score in patients accepted for liver transplantation in 1999 and 2004A Floden
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
Transplant Proc 39:385-6. 2007..We analyzed the gender, age, and MELD score associated with different indications for OLT during this period...
Liver transplantation for treatment of metastatic neuroendocrine tumorsHakan Ahlman
Department of Surgery and Department of Pathology, Goteborg University, Sahlgrenska University Hospital, Goteborg, Sweden
Ann N Y Acad Sci 1014:265-9. 2004..The experience with multivisceral transplantation is still limited...
Auxiliary liver and combined kidney transplantation prevents hyperacute kidney rejection in highly sensitized patientsM Olausson
Department of Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 34:3106-7. 2002
Pseudoaneurysm of the hepatic artery following liver transplantationJ Fistouris
Department of Transplantation and Liver Surgery Sahlgrenska University Hospital, Gothenburg, Sweden
Transplant Proc 38:2679-82. 2006....
Successful ABO-incompatible liver transplantation using A2 donorsU Skogsberg
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transplant Proc 38:2667-70. 2006..We herein have reported our experience with ABO-incompatible liver transplantation using A(2) donors to blood group O recipients...
The cadaveric organ donor program at Sahlgrenska University Hospital, 1977 to 2005C Lovén
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Goteborg, Sweden
Transplant Proc 38:2631-2. 2006..9 organs per donor. These results may be explained by improved organ donor care and organization, and by increased awareness of potential donors among elderly patients...
Outcome of renal transplantation subsequent to liver, heart, or lung transplantationH Tarnow
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 38:2649-50. 2006..The outcome of renal transplantation subsequent to liver, heart, or lung transplantation is good with satisfactory renal function in this study population...
Conversion to sirolimus after kidney and liver transplantation: indications and outcomesL Wramner
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
Transplant Proc 35:791. 2003
Acetazolamide inhibits stimulated feline liver and gallbladder bicarbonate secretionB Nilsson
Department of Surgery, Sahlgrenska University Hospital, , Sweden
Acta Physiol Scand 174:117-23. 2002..The presence of CA II in the gallbladder was demonstrated by immunoblotting. Biliary CA activity has an important function in the regulation of VIP- and secretin-stimulated bicarbonate secretion across the gallbladder mucosa...
Successful combined partial auxiliary liver and kidney transplantation in highly sensitized cross-match positive recipientsM Olausson
Department of Transplantation and Liver Surgery, Sahlgrenska Universith Hospital, Goteborg, Sweden
Am J Transplant 7:130-6. 2007....
MELD [corrected] score in patients accepted for liver transplantation 1994 to 2004A Floden
Department of Transplantation and Liver Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
Transplant Proc 38:2673-4. 2006..Patients with acute hepatic failure had the highest MELD scores while patients undergoing OLT because of malignancy had the lowest MELD score. MELD score seemed to be a useful tool for retrospective analyzes of potential OLT recipients...
Initial experience with multivisceral, cluster, and combined liver and small bowel transplantation in SwedenG Herlenius
Department of Liver and Transplant Surgery, Sahlgrenska University Hospital, , Sweden
Transplant Proc 34:865. 2002
Early recurrence of nephrotic syndrome (immunoglobulin m nephropathy) after renal transplantation successfully treated with combinations of plasma exchanges, immunoglobulin, and rituximabS Westphal
Department of Pediatrics, The Queen Silvia Children s Hospital, Goteborg, Sweden
Transplant Proc 38:2659-60. 2006..Successful treatment included a combination of plasma exchanges, rituximab, immunoglobulin, and antithymocyte globulin...
[Liver transplantation--from experiment to routine care. Experiences from the first 500 liver transplantations in Gothenburg]M Olausson
,
Lakartidningen 98:4556-62, 4564. 2001..This article also describes our experience of in situ splitting and living-related liver transplantation as well as other innovations such as cavoportal hemitransposition and multivisceral transplantation...
Outcome following liver transplantation for primary sclerosing cholangitis in the Nordic countriesB Brandsaeter
Dept of Medicine, Rikshospitalet, Oslo, Norway
Scand J Gastroenterol 38:1176-83. 2003..Because these patients are difficult to evaluate with regard to timing of liver transplantation, it is important to establish predictors of post-transplant survival...
Hepatobiliary carcinoma in primary sclerosing cholangitis: a case control studyM Leidenius
Transplantation and Liver Surgery, Helsinki University Hospital, Finland
J Hepatol 34:792-8. 2001..0005). CONCLUSIONS: The relatively short duration of PSC and the absence of varices in patients with BDC suggest that BDC, unlike HCC, is not necessarily a late complication of end-stage PSC, as was previously assumed...
Highly urgent liver transplantation: possible impact of donor-recipient ABO matching on the outcome after transplantationK Bjøro
Department of Medicine, Rikshospitalet, Oslo, Norway
Transplantation 75:347-53. 2003..Survival after liver transplantation for fulminant hepatic failure has been reported to be less favorable than survival for patients with chronic liver diseases...
Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantationF Vincenti
Kidney Transplant Service, UCSF, San Francisco, California 94143, USA
Transplant Proc 37:1001-4. 2005..At 3 months, median GFR (Nankivell) was 63.7 mL/min; median serum creatinine was 137 micromol/L. Full complete results are expected in December 2005...
