Lena Björkman

Summary

Affiliation: Sahlgrenska University Hospital
Country: Sweden

Publications

  1. doi The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation
    Lena Björkman
    Sahlgrenska Academy, University of Gothenburg, Department of Rheumatology and Inflammation Research, Gothenburg, Sweden
    Arthritis Rheum 62:1660-5. 2010
  2. ncbi Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1
    Lena Björkman
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Leukoc Biol 83:245-53. 2008
  3. pmc The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide
    Huamei Fu
    Department of Rheumatology and Inflammation Research, University of Goteborg, Sweden
    BMC Cell Biol 5:50. 2004
  4. doi Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events
    Huamei Fu
    Department of Rheumatology and Inflammation Research, University of Goteborg, Guldhedsgatan 10, S 413 46 Goteborg, Sweden
    J Immunol Methods 331:50-8. 2008
  5. doi A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils
    Jennie Karlsson
    Department of Rheumatology and Inflammation Research, University of Gothenburg, Guldhedsgatan 10, 413 46 Goteborg, Sweden
    J Immunol Methods 352:45-53. 2010
  6. pmc The Human Neutrophil Subsets Defined by the Presence or Absence of OLFM4 Both Transmigrate into Tissue In Vivo and Give Rise to Distinct NETs In Vitro
    Amanda Welin
    The Phagocyte Research Group, Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden
    PLoS ONE 8:e69575. 2013
  7. ncbi Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7-sensitive pathway independent of formyl peptide receptor-like 1
    Karin Christenson
    Department of Rheumatology and Inflammation Research, Goteborg University, Guldhedsgatan 10, 413 46 Goteborg, Sweden
    J Leukoc Biol 83:139-48. 2008
  8. doi A simple skin blister technique for the study of in vivo transmigration of human leukocytes
    Lisa Davidsson
    The Phagocyte Research Group, Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at the University of Gothenburg, Sweden
    J Immunol Methods 393:8-17. 2013
  9. doi Regulation of neutrophil apoptosis differs after in vivo transmigration to skin chambers and synovial fluid: a role for inflammasome-dependent interleukin-1β release
    Karin Christenson
    The Phagocyte Research Laboratory, Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
    J Innate Immun 5:377-88. 2013
  10. pmc Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors
    Karin Christenson
    The Phagocyte Research Laboratory, Department of Rheumatology and Inflammation Research, EULAR Centre of Excellence in Rheumatology, Sahlgrenska Academy, University of Gothenburg Gothenburg, Sweden
    Front Immunol 4:92. 2013

Collaborators

Detail Information

Publications11

  1. doi The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation
    Lena Björkman
    Sahlgrenska Academy, University of Gothenburg, Department of Rheumatology and Inflammation Research, Gothenburg, Sweden
    Arthritis Rheum 62:1660-5. 2010
    ..The present study was undertaken to investigate whether SAA in the plasma of patients with RA possesses proinflammatory properties and activates neutrophils in a manner similar to that of the recombinant protein...
  2. ncbi Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1
    Lena Björkman
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Leukoc Biol 83:245-53. 2008
    ..Future identification and characterization of the SAA receptor could lead to development of novel, therapeutic targets for treatment of RA...
  3. pmc The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide
    Huamei Fu
    Department of Rheumatology and Inflammation Research, University of Goteborg, Sweden
    BMC Cell Biol 5:50. 2004
    ....
  4. doi Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events
    Huamei Fu
    Department of Rheumatology and Inflammation Research, University of Goteborg, Guldhedsgatan 10, S 413 46 Goteborg, Sweden
    J Immunol Methods 331:50-8. 2008
    ....
  5. doi A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils
    Jennie Karlsson
    Department of Rheumatology and Inflammation Research, University of Gothenburg, Guldhedsgatan 10, 413 46 Goteborg, Sweden
    J Immunol Methods 352:45-53. 2010
    ....
  6. pmc The Human Neutrophil Subsets Defined by the Presence or Absence of OLFM4 Both Transmigrate into Tissue In Vivo and Give Rise to Distinct NETs In Vitro
    Amanda Welin
    The Phagocyte Research Group, Department of Rheumatology and Inflammation Research, University of Gothenburg, Gothenburg, Sweden
    PLoS ONE 8:e69575. 2013
    ..Furthermore, we demonstrate NETs characterized by different markers for the first time, and our results open up for functions of OLFM4 itself in the extracellular space through exposure in NETs. ..
  7. ncbi Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7-sensitive pathway independent of formyl peptide receptor-like 1
    Karin Christenson
    Department of Rheumatology and Inflammation Research, Goteborg University, Guldhedsgatan 10, 413 46 Goteborg, Sweden
    J Leukoc Biol 83:139-48. 2008
    ....
  8. doi A simple skin blister technique for the study of in vivo transmigration of human leukocytes
    Lisa Davidsson
    The Phagocyte Research Group, Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at the University of Gothenburg, Sweden
    J Immunol Methods 393:8-17. 2013
    ....
  9. doi Regulation of neutrophil apoptosis differs after in vivo transmigration to skin chambers and synovial fluid: a role for inflammasome-dependent interleukin-1β release
    Karin Christenson
    The Phagocyte Research Laboratory, Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
    J Innate Immun 5:377-88. 2013
    ....
  10. pmc Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors
    Karin Christenson
    The Phagocyte Research Laboratory, Department of Rheumatology and Inflammation Research, EULAR Centre of Excellence in Rheumatology, Sahlgrenska Academy, University of Gothenburg Gothenburg, Sweden
    Front Immunol 4:92. 2013
    ..We conclude that even though recombinant SAAs can be valuable tools for studying neutrophil activation, they do not reflect the nature of the endogenous protein...
  11. pmc Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activity
    Chunsheng Jin
    Department of Medical Biochemistry, Institute of Biomedicine, University of Gothenburg, 405 30 Gothenburg, Sweden
    J Biol Chem 287:35922-33. 2012
    ..These observations suggest that lubricin is able to bind to PMN via an L-selectin-dependent and -independent manner and may play a role in PMN-mediated inflammation...