Martin Adiels

Summary

Affiliation: Sahlgrenska University Hospital
Country: Sweden

Publications

  1. ncbi request reprint A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions
    Martin Adiels
    Mathematical Sciences, Chalmers University of Technology, 412 96 Goteborg, Sweden
    J Lipid Res 46:58-67. 2005
  2. ncbi request reprint Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia
    Martin Adiels
    Department of Mathematical Sciences, Chalmers University of Technology, Goteborg, Sweden
    Arterioscler Thromb Vasc Biol 25:1697-703. 2005
  3. doi request reprint Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity
    Martin Adiels
    Sahlgrenska Center for Cardiovascular and Metabolic Research Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden
    Atherosclerosis 222:222-8. 2012
  4. doi request reprint Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins
    Martin Adiels
    Wallenberg Laboratory Sahlgrenska Center for Cardiovascular and Metabolic Research, Goteborg University, 413 45 Goteborg, Sweden
    Rapid Commun Mass Spectrom 24:586-92. 2010
  5. ncbi request reprint Fatty liver, insulin resistance, and dyslipidemia
    Martin Adiels
    Wallenberglaboratoriet, Bruna Straket 16, Sahlgrenska University Hospital, 41345 Goteborg, Sweden
    Curr Diab Rep 8:60-4. 2008
  6. doi request reprint Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome
    Martin Adiels
    Wallenberg Laboratory, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden
    Arterioscler Thromb Vasc Biol 28:1225-36. 2008
  7. doi request reprint Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
    Carlo Pirazzi
    Sahlgrenska Center for Cardiovascular and Metabolic Research Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden
    J Hepatol 57:1276-82. 2012
  8. doi request reprint Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles
    Marcus Ståhlman
    Sahlgrenska Center for Cardiovascular and Metabolic Research Wallenberg Laboratory, Goteborg University, Goteborg, Sweden
    Biochim Biophys Acta 1831:1609-17. 2013
  9. doi request reprint Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations
    Martin Berglund
    Department of Mathematical Sciences, University of Gothenburg, Gothenburg, Sweden
    Math Med Biol 29:361-84. 2012
  10. doi request reprint PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals
    Maria Antonella Burza
    Department of Molecular and Clinical Medicine and Center for Cardiovascular and Metabolic Research, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Dig Liver Dis 44:1037-41. 2012

Collaborators

Detail Information

Publications12

  1. ncbi request reprint A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions
    Martin Adiels
    Mathematical Sciences, Chalmers University of Technology, 412 96 Goteborg, Sweden
    J Lipid Res 46:58-67. 2005
    ..These observations are consistent with a sequential assembly model of VLDL and suggest that the TG is added to a primordial apoB-containing particle in the liver...
  2. ncbi request reprint Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia
    Martin Adiels
    Department of Mathematical Sciences, Chalmers University of Technology, Goteborg, Sweden
    Arterioscler Thromb Vasc Biol 25:1697-703. 2005
    ..We sought to compare the synthesis and metabolism of VLDL1 and VLDL2 in patients with type 2 diabetes mellitus (DM2) and nondiabetic subjects...
  3. doi request reprint Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity
    Martin Adiels
    Sahlgrenska Center for Cardiovascular and Metabolic Research Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden
    Atherosclerosis 222:222-8. 2012
    ..To better understand the postprandial clearance of triglyceride-rich lipoproteins (TRLs) and its relation to the fasting kinetics of TRLs...
  4. doi request reprint Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins
    Martin Adiels
    Wallenberg Laboratory Sahlgrenska Center for Cardiovascular and Metabolic Research, Goteborg University, 413 45 Goteborg, Sweden
    Rapid Commun Mass Spectrom 24:586-92. 2010
    ..We now have a robust method to measure glycerol isotopic enrichment by GC/EI-MS that can be used to rule out the known problem of tracer recycling in studies of VLDL kinetics...
  5. ncbi request reprint Fatty liver, insulin resistance, and dyslipidemia
    Martin Adiels
    Wallenberglaboratoriet, Bruna Straket 16, Sahlgrenska University Hospital, 41345 Goteborg, Sweden
    Curr Diab Rep 8:60-4. 2008
    ..In this article, we review recent findings on the development of fatty liver and its role in the diabetic dyslipidemia pathogenesis...
  6. doi request reprint Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome
    Martin Adiels
    Wallenberg Laboratory, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden
    Arterioscler Thromb Vasc Biol 28:1225-36. 2008
    ..Finally, we briefly discuss current treatments for lipid management of dyslipidemia and potential future therapeutic targets...
  7. doi request reprint Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro
    Carlo Pirazzi
    Sahlgrenska Center for Cardiovascular and Metabolic Research Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden
    J Hepatol 57:1276-82. 2012
    ....
  8. doi request reprint Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: impact on small HDL particles
    Marcus Ståhlman
    Sahlgrenska Center for Cardiovascular and Metabolic Research Wallenberg Laboratory, Goteborg University, Goteborg, Sweden
    Biochim Biophys Acta 1831:1609-17. 2013
    ..Furthermore, dyslipidemia alters the cargo of bioactive lipids, with implications for HDL function. ..
  9. doi request reprint Investigations of a compartmental model for leucine kinetics using non-linear mixed effects models with ordinary and stochastic differential equations
    Martin Berglund
    Department of Mathematical Sciences, University of Gothenburg, Gothenburg, Sweden
    Math Med Biol 29:361-84. 2012
    ..In conclusion, NLME models offers improved estimates for model parameters in complex models based on tracer/tracee data and may be a suitable tool to reduce data sampling in clinical studies...
  10. doi request reprint PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals
    Maria Antonella Burza
    Department of Molecular and Clinical Medicine and Center for Cardiovascular and Metabolic Research, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Dig Liver Dis 44:1037-41. 2012
    ..In the present study we examined the association between the PNPLA3 I148M genetic variant and hepatocellular carcinoma in obese individuals from the Swedish Obese Subjects cohort (n = 4047)...
  11. ncbi request reprint Diabetic dyslipidaemia
    Martin Adiels
    Sahlgrenska Center for Metabolism and Cardiovascular Research, Wallenberg Laboratory for Cardiovascular Research and the Department of Metabolism and Cardiovascular Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Curr Opin Lipidol 17:238-46. 2006
    ..This review discusses the pathophysiology of very low density lipoprotein metabolism in type 2 diabetes and recent concepts of lipid management of diabetic dyslipidaemia...
  12. ncbi request reprint How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant hypercholesterolemia?
    Pernilla Jirholt
    Arterioscler Thromb Vasc Biol 24:1334-6. 2004