Emma Lundberg

Summary

Affiliation: Royal Institute of Technology
Country: Sweden

Publications

  1. doi request reprint Creation of an antibody-based subcellular protein atlas
    Emma Lundberg
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, Stockholm, Sweden
    Proteomics 10:3984-96. 2010
  2. doi request reprint Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP)
    Linn Fagerberg
    Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden
    J Proteome Res 12:2439-48. 2013
  3. doi request reprint Antibody performance in western blot applications is context-dependent
    Cajsa Algenäs
    Division of Proteomics, School of Biotechnology, AlbaNova University Center, KTH Royal Institute of Technology, Stockholm, Sweden
    Biotechnol J 9:435-45. 2014
  4. pmc Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model
    Frida Danielsson
    Science for Life Laboratory, Royal Institute of Technology KTH, SE 17121 Solna, Sweden
    Proc Natl Acad Sci U S A 110:6853-8. 2013
  5. doi request reprint Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
    Charlotte Stadler
    KTH Royal Institute of Technology, Science for Life Laboratory, School of Biotechnology, Stockholm, Sweden
    Nat Methods 10:315-23. 2013
  6. doi request reprint Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy
    Charlotte Stadler
    Science for Life Laboratory, Royal Institute of Technology, Stockholm, SE 171 65, Sweden
    J Proteomics 75:2236-51. 2012
  7. doi request reprint The correlation between cellular size and protein expression levels--normalization for global protein profiling
    Emma Lundberg
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, SE 106 91 Stockholm, Sweden
    J Proteomics 71:448-60. 2008
  8. doi request reprint Selection and characterisation of affibody molecules inhibiting the interaction between Ras and Raf in vitro
    Sebastian Grimm
    Division of Molecular Biotechnology, Royal Institute of Technology, Stockholm, Sweden
    N Biotechnol 27:766-73. 2010
  9. ncbi request reprint Mapping the subcellular protein distribution in three human cell lines
    Linn Fagerberg
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, Stockholm, SE 106 91, Sweden
    J Proteome Res 10:3766-77. 2011
  10. pmc Generation of monospecific antibodies based on affinity capture of polyclonal antibodies
    Barbara Hjelm
    Department of Biotechnology, AlbaNova University Center, Royal Institute of Technology, 10691 Stockholm, Sweden
    Protein Sci 20:1824-35. 2011

Collaborators

Detail Information

Publications18

  1. doi request reprint Creation of an antibody-based subcellular protein atlas
    Emma Lundberg
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, Stockholm, Sweden
    Proteomics 10:3984-96. 2010
    ..The considerations made when creating the subcellular protein atlas and critical parameters of this approach are discussed...
  2. doi request reprint Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP)
    Linn Fagerberg
    Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden
    J Proteome Res 12:2439-48. 2013
    ..The status for each gene with regards to protein evidence is visualized in a chromosome-centric manner as part of a new version of the Human Protein Atlas ( www.proteinatlas.org )...
  3. doi request reprint Antibody performance in western blot applications is context-dependent
    Cajsa Algenäs
    Division of Proteomics, School of Biotechnology, AlbaNova University Center, KTH Royal Institute of Technology, Stockholm, Sweden
    Biotechnol J 9:435-45. 2014
    ..Our data implicate that solely using one platform for antibody validation might give misleading information and therefore at least one additional method should be used to verify the achieved data. ..
  4. pmc Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model
    Frida Danielsson
    Science for Life Laboratory, Royal Institute of Technology KTH, SE 17121 Solna, Sweden
    Proc Natl Acad Sci U S A 110:6853-8. 2013
    ..This shows that this comprehensive demonstration of the molecular changes underlying malignant transformation is a relevant model to study the process of tumor formation...
  5. doi request reprint Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
    Charlotte Stadler
    KTH Royal Institute of Technology, Science for Life Laboratory, School of Biotechnology, Stockholm, Sweden
    Nat Methods 10:315-23. 2013
    ..These results show that both IF and FP tagging are reliable techniques and demonstrate the usefulness of an integrative approach for a complete investigation of the subcellular human proteome...
  6. doi request reprint Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy
    Charlotte Stadler
    Science for Life Laboratory, Royal Institute of Technology, Stockholm, SE 171 65, Sweden
    J Proteomics 75:2236-51. 2012
    ..With a large fraction of the human proteome still unexplored, we suggest this approach to be of great importance under the continued work of mapping the human proteome on a subcellular level...
  7. doi request reprint The correlation between cellular size and protein expression levels--normalization for global protein profiling
    Emma Lundberg
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, SE 106 91 Stockholm, Sweden
    J Proteomics 71:448-60. 2008
    ..The results demonstrate the value of large-scale, automated proteome analysis using immunohistochemistry, in revealing functional correlations and establishing methods to interpret and mine proteomic data...
  8. doi request reprint Selection and characterisation of affibody molecules inhibiting the interaction between Ras and Raf in vitro
    Sebastian Grimm
    Division of Molecular Biotechnology, Royal Institute of Technology, Stockholm, Sweden
    N Biotechnol 27:766-73. 2010
    ..Possible intracellular applications of the selected affibody molecules are discussed...
  9. ncbi request reprint Mapping the subcellular protein distribution in three human cell lines
    Linn Fagerberg
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, Stockholm, SE 106 91, Sweden
    J Proteome Res 10:3766-77. 2011
    ..Our results show distinct organelle proteomes, well conserved across the cell types, and demonstrate that biochemically similar organelles are grouped together...
  10. pmc Generation of monospecific antibodies based on affinity capture of polyclonal antibodies
    Barbara Hjelm
    Department of Biotechnology, AlbaNova University Center, Royal Institute of Technology, 10691 Stockholm, Sweden
    Protein Sci 20:1824-35. 2011
    ....
  11. pmc Defining the transcriptome and proteome in three functionally different human cell lines
    Emma Lundberg
    Science for Life Laboratory, Royal Institute of Technology, Stockholm, Sweden
    Mol Syst Biol 6:450. 2010
    ..Thus, this study shows a path to characterize the transcriptome and proteome in human cells from different origins...
  12. doi request reprint A single fixation protocol for proteome-wide immunofluorescence localization studies
    Charlotte Stadler
    School of Biotechnology, AlbaNova University Center, Royal Institute of Technology KTH, SE 106 91 Stockholm, Sweden
    J Proteomics 73:1067-78. 2010
    ....
  13. pmc Analysis of transcript and protein overlap in a human osteosarcoma cell line
    Daniel Klevebring
    Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, SE 171 65 Solna, Sweden
    BMC Genomics 11:684. 2010
    ....
  14. doi request reprint A genecentric Human Protein Atlas for expression profiles based on antibodies
    Lisa Berglund
    Department of Proteomics, School of Biotechnology, AlbaNova University Center, Royal Institute of Technology, Stockholm, Sweden
    Mol Cell Proteomics 7:2019-27. 2008
    ..The new version of the protein atlas thus is a resource for many areas of biomedical research, including protein science and biomarker discovery...
  15. ncbi request reprint Affibody-mediated retention of the epidermal growth factor receptor in the secretory compartments leads to inhibition of phosphorylation in the kinase domain
    Erik Vernet
    Department of Molecular Biotechnology, Royal Institute of Technology KTH, AlbaNova University Center, 10691 Stockholm, Sweden
    N Biotechnol 25:417-23. 2009
    ..Surface depletion of EGFR led to a dramatic decrease in the amount of kinase domain phosphorylated EGFR, coincident with a significant decrease in the proliferation rate...
  16. doi request reprint Selection and characterization of Affibody ligands to the transcription factor c-Jun
    Emma Lundberg
    School of Biotechnology, AlbaNova University Center, Kungliga Tekniska Högskolan, Stockholm, Sweden
    Biotechnol Appl Biochem 52:17-27. 2009
    ..The potential intracellular use of Affibody ligands directed against transcription factors and other oncogenic factors is discussed...
  17. ncbi request reprint Toward a confocal subcellular atlas of the human proteome
    Laurent Barbe
    Department of Biotechnology, AlbaNova University Center, Royal Institute of Technology, SE 106 91 Stockholm, Sweden
    Mol Cell Proteomics 7:499-508. 2008
    ..The results suggest that this approach might be a valuable tool in conjunction with predictive models for protein localization...
  18. pmc Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs
    Beata Werne Solnestam
    KTH Royal Institute of Technology, Science for Life Laboratory SciLifeLab Stockholm, School of Biotechnology, Division of Gene Technology, SE 171 65, Solna, Sweden
    BMC Genomics 13:574. 2012
    ..In this study, mRNA fractions from the cytoplasm and from whole cells (total RNA) were prepared from three human cell lines and sequenced using massive parallel sequencing...